Meister Bio

What Meister Bio does

Meisterbio Co., Ltd. (マイスターバイオ株式会社) is a private Japanese health foods, cosmetics, and drug development company founded on April 8, 2008, in Okayama, Japan. The company is led by founder Professor Hiroki Hamada, who holds a doctorate in science from Hiroshima University and serves concurrently as President, CEO, and CTO. Meister Bio operates at the intersection of preventive-medicine research and consumer product commercialization, translating natural active ingredients — including resveratrol, CoQ10, NMN, and paclitaxel — into supplements, functional beverages, and topical cosmetics. Its proprietary Technol PG nanoparticle platform underpins the technical differentiation: a claimed world-first water-soluble Taxol (paclitaxel) formulation, water-soluble trans-resveratrol glycoside cosmetics, cluster dextrin clathrate CoQ10, transdermal anionic nanoparticle formulations for skin cancer and wrinkle treatment, capsaicin glycosides, and BBB-penetrating memantine oligosaccharides for anti-dementia applications.

The company markets seven core consumer products — the NMN + Resveratrol supplement, Le Resveratrol drink, Sakuna Q10 Wrinkle Care Series (lotion, essence, cream), Metagainst ULTRA EX, HMD Tonic, Hamada's Aojiru MB, and Glucoside Vitamin C — priced between ¥4,000 and ¥10,000 per unit (tax excluded). Distribution is exclusively domestic Japan, executed via telephone, FAX, email, and a proprietary e-commerce storefront (meisterbio.base.shop), with fulfillment by Yamato Transport TA-Q-BIN. Three revenue streams are disclosed: DTC product sales, OEM manufacturing services for third-party health food and cosmetics brands, and clinical data / ingredient measurement services.

Meister Bio monetizes a substantial R&D network comprising 25+ joint corporate research partners (Mitsubishi Corporation, Otsuka Pharmaceutical, Chugai Pharmaceutical, FANCL, Mitsubishi Chemical, Nichirei, Ezaki Glico, Nagase, Kanehide Bio, Eli Lilly, Aphios) and 20+ university collaborators (Tokyo, Tohoku, Okayama, Hiroshima, Harvard, UCLA, UC Berkeley, UCSF, Texas A&M). The founder's research output includes 158+ peer-reviewed publications spanning Nat. Prod. Commun., Anticancer Res., and related journals, with awards including the University-originated Venture Award (2008), Uchiyama Yuzo Award (2010), and Plant Cell Biology Society award (2011). The company is privately held, founder-controlled, with ¥8,000,000 in registered capital and no disclosed external funding.

Name

Meister Bio

Legal name

Meisterbio Co., Ltd.

Website

https://meisterbio.co.jp

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

1–10 employees

Short description

Meisterbio Co., Ltd. is a private Japanese health foods, cosmetics, and drug development company founded in 2008 that commercializes Professor Hiroki Hamada's preventive-medicine research through seven DTC consumer products, OEM manufacturing, and a proprietary Technol PG nanoparticle platform.

Ownership category

akta.pro rank

Product category

Nutraceuticals and Cosmeceuticals

NAICS

Medicinal and Botanical Manufacturing (325411)

SIC

Medicinal Chemicals & Botanical Products (2833), Food And Kindred Products (2000)

akta.pro industry

PRIMARYAFAJAKAI

Antioxidants & Phytochemicals (Carotenoids, Tocopherols, Flavonoids, CoQ10, Resveratrol)

Agriculture & Food Production/Food Ingredients & Additives/Nutraceutical & Functional Ingredients (Vitamins, Minerals, Omega-3s, Botanicals)

SECONDARYAFAFAFAF

Botanical/Herbal & Adaptogen Functional Beverage Production

Agriculture & Food Production/Beverage Production/Functional & Nutritional Beverage Production (Energy, Sports, Fortified)

SECONDARYAFAJAKAK

Condition-Specific Bioactives (Glucosamine/Chondroitin, Plant Sterols, Melatonin, Lutein/Zeaxanthin)

Agriculture & Food Production/Food Ingredients & Additives/Nutraceutical & Functional Ingredients (Vitamins, Minerals, Omega-3s, Botanicals)

SECONDARYEUAAAIAK

Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives

Energy, Utilities & Environment/Bioenergy, Natural Gas & Biomass/Biorefining & Bio-based Chemicals (Co-products, Bioproducts)

Keywords

• Functional food supplements
• Anti-aging cosmetics
• Nanoparticle drug delivery
• OEM health manufacturing
• Preventive medicine research

Headquarters

HQ city

Okayama

HQ country

Japan

HQ region

Asia

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales

Revenue model

1. Health foods and cosmetics sales: Direct sales of proprietary health food and cosmetic products including Resveratrol (Le Resveratrol), Sakuna Q10 series, NMN+Resveratrol supplements, Metagainst, HMD tonic, Hamada's Aojiru, and Glucoside Vitamin C. Sold directly to consumers via telephone, FAX, e-mail, and own e-commerce storefront.
2. OEM manufacturing services: OEM production of health foods and cosmetics for other brands, leveraging proprietary ingredient technologies and research capabilities.
3. Clinical data and ingredient measurement services: Provision of clinical data, measurements, and research services for raw materials, ingredients, and formulations.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels3 records

Core offering

Meister Bio researches, develops, manufactures, and sells health food supplements and topical anti-aging cosmetics formulated from natural active ingredients (resveratrol, NMN, CoQ10, glucosides, capsaicin glycosides), leveraging its proprietary Technol PG nanoparticle platform for transdermal and oral delivery. In parallel it offers OEM manufacturing of health foods and cosmetics and clinical-data/measurement services to third-party brands and ingredient suppliers.

Product overview

Meister Bio is a health foods and cosmetics company offering a portfolio of seven distinct products developed by Professor Emeritus Hiroki Hamada (CEO/CTO) from Okayama University of Science. The product line includes oral supplements (NMN+ Resveratrol, Resveratrol drink, Metagainst, HMD Tonic, Glucoside Vitamin C), topical cosmetics (Sakuna Q10 Wrinkle Care Series with lotion, essence, and cream), and functional beverages (Hamada's Aojiru MB). The company develops products utilizing natural active ingredients from foods and plants, with research focused on anti-aging, cell oxidation inhibition, and preventive medicine applications. OEM manufacturing for health foods and cosmetics is also offered.

Differentiator

Problem solved

Functional benefit

Brands

• レ・レスベラトロール (Le Resveratrol): Resveratrol drink made from Okayama Pione grape skin extract, marketed as a 'drinkable cosmetic' for beauty and health.
• サクナQ10 (Sakuna Q10)
• メタゲインスト ULTRA EX (Metagainst ULTRA EX)
• HMDトニック (HMD Tonic)
• ハマダの青汁 MB (Hamada's Aojiru MB)
• グルコシドビタミンＣ (Glucoside Vitamin C)
• NMN＋レスベラトロール (NMN + Resveratrol Supplement)

Products and services

• Le Resveratrol (レ・レスベラトロール) A beauty-health functional drink (50ml × 10 bottles, 7,500 JPY tax excluded) made from resveratrol extracted from Okayama Pione grape skin, marketed as 'drinkable cosmetics' that suppress cellular oxidation for beauty and health maintenance, targeting health-conscious Japanese consumers.
• Sakuna Q10 Lotion (サクナQ10ローション) Topical anti-aging lotion (120ml, 5,000 JPY tax excluded) from the Sakuna Q10 series, combining Coenzyme Q10 with Botan Bofu (Peucedanum japonicum) leaf extract for cell oxidation control, detoxification, and skin moisturizing.
• Sakuna Q10 Essence (サクナQ10エッセンス) Concentrated anti-aging essence (30ml, 10,000 JPY tax excluded) from the Sakuna Q10 series with Coenzyme Q10 and Botan Bofu (Peucedanum japonicum) leaf extract for advanced wrinkle care and skin renewal.
• Sakuna Q10 Cream (サクナQ10クリーム) Anti-aging facial cream (40g, 7,000 JPY tax excluded) from the Sakuna Q10 series containing Coenzyme Q10 and Botan Bofu (Peucedanum japonicum) leaf extract for cell oxidation control, detoxification, and skin moisturizing.
• NMN + Resveratrol Supplement (NMN＋レスベラトロール サプリ) Oral anti-aging supplement combining 99%+ purity NMN (200mg per capsule) with grape bud extract and resveratrol (5mg per 2 capsules) to increase NAD+ levels through complementary mechanisms — NMN as NAD+ precursor and resveratrol as PDE4 inhibitor promoting NAD+ production — for adult consumers seeking longevity and metabolic support.
• Metagainst ULTRA EX (メタゲインスト ウルトラEX) Metabolic-support health supplement (250mg × 180 pills) in the Metagainst product line, formulated for daily health maintenance and metabolic support in adult consumers.
• HMD Tonic (HMDトニック) Tonic health drink (4,000 JPY tax excluded) developed by Professor Hamada for vitality and general health support in adult consumers.
• Hamada's Aojiru MB (ハマダの青汁 MB) Green barley juice (aojiru) supplement (3g × 30 packets per box) developed by Dr. Hamada as a daily health beverage providing nutritional support from natural plant ingredients.
• Glucoside Vitamin C (グルコシドビタミンC) Stabilized Vitamin C glucoside supplement (2g × 30 packets per box) using a glycoside derivative for enhanced absorption, marketed for skin health and antioxidant support.
• OEM Manufacturing Services for Health Foods and Cosmetics B2B contract manufacturing service for other brands' health foods and cosmetics, leveraging Meister Bio's proprietary ingredient technologies, glycosylation IP, and clinical research capabilities to deliver finished products for partner brands.
• Clinical Data and Ingredient Measurement Services Research and measurement service providing clinical data, ingredient characterization, and formulation support for raw materials, ingredients, and finished health-food or cosmetic products, drawing on Meister Bio's preventive-medicine research infrastructure.

Quantifiable outcome

• World's first water-soluble Taxol anti-cancer agent with no side effects
• +2 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Partnerships

24 partnerships are on record, tiered core and minor.

• Mitsubishi Corporation (三菱商事株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner in the Le Resveratrol Project (2008, 2010). One of the largest joint research collaborations in Meister Bio's industry-academia-government ecosystem.
• Mitsubishi Chemical Corporation (三菱化学株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner contributing to drug development and functional food material research.
• Nichirei Corporation (株式会社ニチレイ)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in food ingredient and functional food development.
• Ensuiko Sugar Refining Co., Ltd. (塩水港精糖株式会社)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in sugar and sweetener-related functional food ingredient research.
• Ezaki Glico Co., Ltd. (江崎グリコ株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner in functional food development leveraging Glico's food science expertise.
• Nagase & Co., Ltd. (長瀬産業株式会社)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in chemical and material science for functional ingredients.
• Mitejima Chemical Co., Ltd. (ミテジマ化学株式会社)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in chemical ingredient development.
• Otsuka Pharmaceutical Co., Ltd. (大塚製薬株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner in pharmaceutical and functional food development, contributing to innovative drug development initiatives.
• Chugai Pharmaceutical Co., Ltd. (中外製薬株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner in innovative drug development, particularly in water-soluble Taxol and nanoparticle-based therapeutics.
• FANCL Corporation (ファンケル株式会社)coreStrategic or Co-development Partner · 8 April 2008Joint research partner in cosmetics and health food development, leveraging FANCL's expertise in additive-free products.
• Kanehide Bio Co., Ltd. (株式会社金秀バイオ)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in bio-related functional ingredient research.
• Fuso Chemical Co., Ltd. (扶桑化学工業株式会社)minorStrategic or Co-development Partner · 8 April 2008Joint research partner in chemical manufacturing and functional ingredient development.
• Aphios Corporation (Boston, U.S.A.)coreStrategic or Co-development Partner · 8 April 2008U.S.-based joint research partner in Boston, contributing to international drug development and nanotechnology research collaborations.
• Eli Lilly and Company (Indianapolis, U.S.A.)coreStrategic or Co-development Partner · 8 April 2008International joint research partner based in Indianapolis, contributing to pharmaceutical development research including water-soluble Taxol and innovative drug delivery.
• University of Tokyo (東京大学)coreStrategic or Co-development Partner · 8 April 2008Collaborative university partner in joint research alongside other Japanese and international academic institutions.
• Harvard UniversitycoreStrategic or Co-development Partner · 8 April 2008International collaborative university partner contributing to preventive medicine and anti-aging research.
• UCLA (University of California, Los Angeles)coreStrategic or Co-development Partner · 8 April 2008International collaborative university partner in anti-aging and functional food research.
• UC Berkeley (University of California, Berkeley)coreStrategic or Co-development Partner · 8 April 2008International collaborative university partner in life sciences and preventive medicine research.
• UCSF (University of California, San Francisco)coreStrategic or Co-development Partner · 8 April 2008International collaborative university partner in biomedical and pharmaceutical research.
• Texas A&M UniversitycoreStrategic or Co-development Partner · 8 April 2008International collaborative university partner; Dr. Hamada served as postdoctoral fellow at Texas A&M's Biochemistry Department, contributing to current research collaborations.
• Shanghai Jiao Tong UniversitycoreStrategic or Co-development Partner · 8 April 2008Dr. Hiroki Hamada appointed as Visiting Professor at Shanghai Jiao Tong University on February 28, 2017, deepening Japan-China academic collaboration.
• Okayama University of Science (岡山理科大学)coreStrategic or Co-development Partner · 8 April 2008Home institution of Professor Hamada (CTO/CEO), where he served as Head of Department of Clinical Life Science. Site of the Le Resveratrol Project (2008, 2010) industry-academia-government collaboration.
• University of ChicagominorStrategic or Co-development Partner · 8 April 2008International collaborative university partner in life sciences and preventive medicine research.
• University of HawaiiminorStrategic or Co-development Partner · 8 April 2008International collaborative university partner in Pacific-region health and nutrition research.

Scale indicators3 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• Pola Orbis Holdings: Japanese cosmetics group with strong proprietary skincare and anti-aging R&D. Comparable on premium, science-backed anti-aging cosmetics such as Meister Bio's Sakuna Q10 wrinkle care line.
• Otsuka Pharmaceutical Co., Ltd. Large Japanese pharmaceutical company with a significant health foods and nutraceutical business (Otsuka Pharmaceutical). Comparable on functional food and pharmaceutical ingredient R&D, and also a joint research partner of Meister Bio.
• Kewpie Corporation: Japanese food company with deep functional ingredient, emulsion, and food science R&D capabilities. Comparable on proprietary ingredient and delivery technology for functional foods and supplements.
• Ezaki Glico Co., Ltd. Major Japanese confectionery and food company with active functional food and ingredient science programs. Comparable on food-based preventive health R&D and also a joint research partner of Meister Bio.
• Mitsubishi Chemical Corporation: Major Japanese chemical company with broad specialty chemicals, functional ingredients, and life sciences businesses. Comparable on specialty ingredient R&D and also a joint research partner of Meister Bio.

Direct peers

• DHC Corporation: Leading Japanese direct-to-consumer supplements and cosmetics brand with a broad functional food portfolio. Highly comparable on DTC supplements-and-cosmetics business model and target customer (health-conscious Japanese consumers).
• FANCL Corporation: Major Japanese supplements and additive-free cosmetics company with proprietary R&D and a similar health/beauty product positioning. FANCL is also an active joint research partner of Meister Bio, making it the closest comparable peer.
• Mibelle Biochemistry: Swiss developer of proprietary bioactive cosmetic and nutraceutical ingredients (e.g., botanical and antioxidant actives). Comparable to Meister Bio's Technol PG delivery and glycosylation-based ingredient innovation.
• ChromaDex, Inc. U.S.-based company focused on NAD+ precursors (NMN, NR) and anti-aging ingredient science with a B2B ingredient supply model. Directly comparable to Meister Bio's NMN+Resveratrol NAD+ boosting formulation and ingredient platform.

Emerging players

• Aphios Corporation: Boston-based biotechnology company focused on nanoparticle drug delivery and pharmaceutical development. Highly comparable on the Technol PG-style nanoparticle drug delivery platform and also a joint research partner of Meister Bio.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Meister Bio