What Cerebrovascular Research Institute does

The Cerebrovascular Research Institute (公益財団法人脳血管研究所, Institute of Brain and Blood Vessels) is a Japanese public interest incorporated foundation established in 1963 and headquartered in Isesaki, Gunma Prefecture. It operates an integrated healthcare delivery platform centered on Mihara Memorial Hospital, a 189-bed specialty hospital (45 acute with 9 SCU beds, 45 disability, 50 recovery rehabilitation, 49 recovery/regional care) certified as a Primary Stroke Center Core by the Japan Stroke Society, providing 24/7 acute stroke care including t-PA thrombolysis and mechanical thrombectomy, and performing approximately 300 neurosurgical and endovascular procedures per year. The foundation also operates ARBOS, a 100-bed geriatric health services facility offering general, dementia-specialty, and unit-type inpatient care plus short-stay and day rehabilitation; Gratia, a visiting nursing station; a home rehabilitation service; a home care support office (Mihara); and Mihara Clinic within the Kenshōkan building.

The foundation maintains three specialty medical centers: the Parkinson's Disease and Movement Disorder (PMD) Center, providing device-assisted therapies including deep brain stimulation (DBS), continuous enteral Duodopa infusion, and continuous subcutaneous Vyalev infusion; the Gunma Dementia Disease Medical Center, the prefecturally designated hub for differential diagnosis, treatment, and consultation, with recently introduced anti-amyloid antibody therapies Lecanemab (Leqembi) and Donanemab (Kisunla); and the Primary Stroke Center Core. Diagnostic and treatment technology includes a 320-row CT scanner (160mm per rotation in 0.25 seconds) for perfusion imaging, dual MRI (1.5T and 3T) for stroke and neurological diagnosis, and SPECT nuclear medicine imaging (including DaTscan and MIBG cardiac scintigraphy) for dementia and Parkinson's differential diagnosis. Rehabilitation services feature the HAL® wearable robotic suit for neurodegenerative diseases (SMA, SBMA, ALS, CMT, hereditary spastic paraplegia) paired with 3D gait analysis. The brain bank is registered with the Japanese Neuropathological Society and participates in the Japan Neuroscience Brain Bank Network.

The foundation operates under Japan's universal health insurance system, with revenue generated primarily through medical insurance reimbursement (DPC/PDPS and designated medical care billing for inpatient acute, recovery, and disability care) and long-term care insurance (介護保険) for ARBOS inpatient services and home-based care. Additional revenue streams include public donations supporting clinical research and dissemination of research outcomes, self-pay Brain Dock preventive screening (¥22,000 basic, ¥27,500 with VSRAD), and high-cost medical expense coverage (高額療養費制度) applied to anti-amyloid infusions. No external investors, parent company, or private equity stake exist; the foundation is governed by Chairman Mihara Ju and Representative Director Mihara Gen under Ministry of Internal Affairs oversight. Geographic reach is regional — primarily Gunma Prefecture with patient spillover from neighboring Saitama, Tochigi, and Nagano — and the workforce includes 119+ rehabilitation staff plus 43 dedicated care workers at ARBOS, plus multidisciplinary nursing, medical, and administrative teams.

Name

Cerebrovascular Research Institute

Legal name

公益rógeno 脳血管研究所 (Institute of Brain and Blood Vessels)

Website

https://mihara-ibbv.jp

Company type

Private

Founded year

1996

Operating status

Operating

Short description

The Cerebrovascular Research Institute (公益財団法人脳血管研究所) is a Japanese public interest foundation operating Mihara Memorial Hospital, ARBOS nursing home, and Gratia visiting nursing, providing integrated stroke, dementia, Parkinson's disease, and neurological care across Gunma Prefecture.

Ownership category

akta.pro rank

Product category

Cerebrovascular and Neurological Specialty Healthcare Services

NAICS

Nursing and Residential Care Facilities (623), Continuing Care Retirement Communities and Assisted Living Facilities for the Elderly (62331), Services for the Elderly and Persons with Disabilities (624120), Nursing Care Facilities (Skilled Nursing Facilities) (62311)

SIC

Services-Hospitals (8060), Services-Nursing & Personal Care Facilities (8050), Services-Home Health Care Services (8082)

akta.pro primary industry

Post-Diagnosis Transition & Hospital-to-Home Dementia Support (HSABAEAL)

akta.pro secondary industries

Alzheimer’s Specialized Care (Mid/Late-Stage) (HSABAEAC), High-Acuity/Late-Stage Dementia & Complex Care (Enhanced Nursing Memory Care) (HLADACAF), Dementia/Alzheimer’s In-Home Care (Non-Medical) (HLADAGAG), Memory Care Respite (Short-Term) (HSABAEAD)

Keywords

• Cerebrovascular care
• Stroke treatment
• Neurological rehabilitation
• Long-term nursing care
• Dementia care

Headquarters

HQ city

Isesaki

HQ country

Japan

HQ region

Asia

Offices5 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales

Revenue model

1. Medical Insurance Reimbursement (Medical Care): Primary revenue stream from Japan's universal health insurance system (National Health Insurance / 後期高齢者医療制度). Mihara Memorial Hospital provides acute care, rehabilitation, and nursing care services billed under the country's DPC/PDPS and designated medical care reimbursement schemes. Revenue encompasses inpatient treatment across acute, subacute (recovery), disability, and comprehensive care bed types.
2. Donations: The foundation operates as a public interest corporation (公益법인) under the jurisdiction of the Ministry of Internal Affairs and Communications (総務省内閣府). Public donations are accepted and used to fund clinical research activities and dissemination of research outcomes for medical advancement.
3. Long-Term Care Insurance Services (介護保険): ARBOS nursing home and Gratia visiting nursing station operate under Japan's long-term care insurance system (介護保険制度), generating revenue from care service fees for elderly and disabled patients, including respite care, short-stay, and day rehabilitation services.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels8 records

Core offering

Cerebrovascular Research Institute operates an integrated specialty care system for cerebrovascular and neurological diseases, anchored by Mihara Memorial Hospital (189 beds) which functions as a Primary Stroke Center Core, a Parkinson's Disease and Movement Disorder Center, and houses the Gunma Dementia Medical Center. The foundation complements acute hospital services with ARBOS nursing home (100 beds) for long-term residential care and Gratia visiting nursing station plus home-visit rehabilitation for community-based chronic and end-of-life care. Additional offerings include Brain Dock preventive brain screening, Robot Suit HAL-based neurorehabilitation covered by Japanese health insurance, VSRAD-based early dementia imaging, and specialty outpatient clinics for driving and employment support for neurological patients.

Product overview

Cerebrovascular Research Institute (公益財団法人脳血管研究所) operates as a medical foundation with a multi-facility care mix model centered on Mihara Memorial Hospital, a specialized neurological and stroke center. The portfolio includes acute care hospital (美原記念病院), geriatric health facility (アルボース), visiting nursing station (グラーチア), and home care support services (居宅介護支援事業所みはら). Specialized medical centers include a Primary Stroke Center (一次脳卒中センター), Parkinson's and Movement Disorder Center (PMDセンター), and Gunma Dementia Medical Center. Rehabilitation services feature robot suit HAL®, brain dock health screenings, driving support clinic, employment support clinic, and visiting rehabilitation. Community facilities include Kenjukukan research building with Tenboku Hall and Gallery m for public education and cultural activities.

Differentiator

Problem solved

Functional benefit

Brands

• 群馬県 dementia疾患医療センター (Gunma Dementia Medical Center): A specialized center for dementia diagnosis, treatment, consultation, and awareness activities operated by Mihara Memorial Hospital.
• パーキンソン病・運動障害(PMD)センター (Parkinson and Movement Disorder Center)
• 一次脳卒中センター(PSC)コア (Primary Stroke Center Core)

Products and services

• Mihara Memorial Hospital (美原記念病院)

Quantifiable outcome

• Dementia disease medical center serves as a regional resource for differential diagnosis and treatment of dementia types
• +3 more outcomes

Named customers3 records

Segments6 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature9 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• Gunma Prefecture (群馬県)coreStrategic or Co-development Partner · 1 January 2025Gunma Prefecture designated Mihara Memorial Hospital as the Gunma Dementia Disease Medical Center (群馬県認知症疾患医療センター), a prefectural-level specialized dementia care hub. The prefecture also commissioned the Gunma Restraint Elimination Research Society (群馬抑制廃止研究会), hosted by ARBOS, to conduct prefecture-wide training on restraint-free care practices.
• All Japan Hospital Association Gunma Branch (全日本病院協会群馬県支部)minorStrategic or Co-development Partner · 1 January 2025Mihara Memorial Hospital serves as the secretariat for the All Japan Hospital Association Gunma Branch, which conducts healthcare worker environment improvement seminars for member hospitals across the prefecture.
• National Center of Neurology and Psychiatry (国立精神・神経医療研究センター/NCNP)coreStrategic or Co-development Partner · 1 January 2025NCNP and the institute maintain collaborative relations through special lectures. NCNP's honorary director 水澤英洋 delivered a lecture on 'NCNP and Brain Bank — Toward Overcoming Prion Disease' at the institute's special lecture series in May 2022.
• Isesaki City (伊勢崎市委)minorStrategic or Co-development Partner · 1 January 2016Isesaki City awarded the Kensōkan building the Hisei City Landscape Town Planning Award in 2016 for its architectural contribution to the urban landscape. The city also commissioned the institute to operate the Isesaki Elderly Consultation Center North/Sango district (伊勢崎市高齢者相談センター北・三郷).
• Japan Neuroscience Brain Bank Network (日本神経科学ブレンバンクネットワーク)coreStrategic or Co-development Partner · 1 January 2014Mihara Memorial Hospital's brain bank participates in the Japan Neuroscience Brain Bank Network as a registered facility of the Japanese Neuropathological Society, contributing brain tissue specimens for neurological disease research.
• Social Welfare Corporation Patagonia (社会福祉法人パトリア)coreOthersPart of the broader Mihara Group (美原グループ), Patagonia operates special nursing home Amichi (特別养护老人ホームアミーキ). Patagonia's facilities are cross-referenced on ARBOS materials as affiliated social welfare organizations within the same community care network.
• Medical Corporation Iari Mihara Clinic (医療法人イアリ美原記念病院)coreOthersAn affiliated medical corporation operating Mihara Clinic within the Kensōkan building (研宗館) adjacent to Mihara Memorial Hospital, providing general neurology and internal medicine services. Cross-referenced as a group legal entity.
• Regional Medical Institutions (協力医ネットワーク)coreChannel Partner/ Reseller/ DistributorMihara Memorial Hospital maintains a network of cooperating physicians (協力医) from regional clinics and hospitals who participate in the hospital's medical coordination system, accepting referrals and coordinating patient care across the local medical community.

Scale indicators6 records

Recent moves7 records

Expansion highlights7 records

Broad incumbents

• SOMPO Care Inc. (SOMPO Holdings): One of Japan's largest operators of paid nursing homes, group homes, and in-home care services under the SOMPO Holdings umbrella. Comparable as a major Japanese player in long-term care insurance-funded services including dementia-focused care, though lacking the acute stroke hospital and specialty neurology dimensions.
• Benesse Style Care Co., Ltd. Large Japanese operator of paid nursing homes and dementia-care facilities, plus home care services. Comparable for ARBOS-style nursing home and dementia ward operations and home-visit services, though focused on for-profit paid facilities rather than foundation-operated care.
• Nichii Gakkan Company: Diversified Japanese care services company operating nursing homes, in-home care, and care staff training/placement. Comparable in offering long-term care, dementia, and home care services under long-term care insurance, though nationally scaled and without an acute hospital foundation anchor.
• Tokyo Saiseikai Central Hospital / Saiseikai Hospitals: Flagship tertiary hospital of the Saiseikai public interest foundation with stroke center, rehabilitation, and home care services. Comparable as a public interest foundation hospital with integrated post-acute services and a regional hub role, though operating at a larger tertiary scale than the Cerebrovascular Research Institute.
• Social Welfare Organization Saiseikai (Imperial Gift Foundation): Large national public interest medical foundation operating a network of hospitals across Japan with various specialty departments including neurology and rehabilitation. Comparable as a multi-facility Japanese public interest incorporated foundation in healthcare, though with broader geographic and specialty scope than the Cerebrovascular Research Institute's regional cerebrovascular focus.

Direct peers

• Tokushukai Medical Group: One of Japan's largest private hospital operators running integrated acute care hospitals, rehabilitation, and elderly care facilities under a single group. Its multi-facility integrated care model and emphasis on regional medical hubs is structurally similar to the Cerebrovascular Research Institute's medical-foundation-plus-nursing-home-plus-home-care structure.
• Kameda Medical Center: Integrated private hospital group in Chiba Prefecture operating acute care hospitals, rehabilitation, nursing care facilities, and home care services under one corporate structure. The care-mix model (acute hospital + nursing home + home care) directly parallels Mihara's hospital/ARBOS/Gratia integrated continuum.
• National Cerebral and Cardiovascular Center (NCVC): Japan's premier national specialty hospital for cerebrovascular and cardiovascular disease under the National Hospital Organization, with stroke thrombectomy, brain bank, and research programs comparable to Mihara Memorial Hospital. Directly comparable as Japan's leading cerebrovascular specialty center serving as a hub for advanced stroke care and neuroscience research.
• SEIREI Social Welfare Group (Seirei Social Welfare Organization): Major Japanese integrated medical and social welfare group operating hospitals, rehabilitation facilities, special nursing homes, and home care services across multiple prefectures. Closely comparable to Mihara's nonprofit foundation structure combining hospital (Mihara Memorial), geriatric facility (ARBOS), and home-based services (Gratia).

Emerging players

• National Center of Neurology and Psychiatry (NCNP): Japan's national center for neurological and psychiatric disorders with hospital, research institute, and brain bank operations. Cited as an active research and special lecture partner of the Cerebrovascular Research Institute. Comparable in research infrastructure and brain bank participation, though operating at a national scale rather than regional.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/arbos.PRteam

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries4 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Cerebrovascular Research Institute