SYMATESE AESTHETICS

Name

SYMATESE AESTHETICS

Legal name

SYMATESE AESTHETICS

Website

https://symatese-aesthetics.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

SYMATESE AESTHETICS is a French MedTech company designing, manufacturing, and commercializing Class III implantable medical devices for plastic surgeons, dermatologists, and burn/wound care specialists. Its portfolio spans HA dermal fillers (ESTYME), silicone breast implants (ESTYME MATRIX), and collagen-based dermal regeneration matrices (NEVELIA), distributed across more than 20 countries.

Ownership category

akta.pro rank

Product category

Aesthetic Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842)

akta.pro primary industry

Dermatology & Aesthetics Pharmaceuticals (HLAIAAAK)

Keywords

• Aesthetic medical devices
• Dermal fillers
• Breast implants
• Dermal regeneration
• Plastic surgery devices

Headquarters

HQ city

Bornel

HQ country

France

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Operations, Personnel, Marketing or Sales, Supply Chain

Revenue model

1. Medical Device Sales (Dermal Fillers, Breast Implants, Dermal Matrices): SYMATESE AESTHETICS generates revenue through the sale of implantable medical devices including ESTYME hyaluronic acid dermal fillers, ESTYME breast implants, and NEVELIA dermal regeneration matrices to plastic surgeons, dermatologists, and healthcare facilities. CE marking for HA fillers and breast implants is in process with one HA product (ESTYME FORM) already CE marked.
2. Surgical Instruments Distribution (Black & Black): Exclusive distribution of premium Black & Black Surgical Instruments in France, including plastic surgery instruments, cannulas for liposuction, infiltration, and fat grafting procedures.
3. Distribution Partnership Revenue: Revenue generated through distributor partnerships where distributors invest in market penetration with SYMATESE AESTHETICS providing marketing and scientific support. Company also offers B2B technology partnerships where partners leverage SYMATESE technology and R&D skills to develop their own solutions.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels7 records

Core offering

SYMATESE AESTHETICS designs, manufactures and markets implantable medical devices for aesthetic medicine and plastic surgery, including cross-linked hyaluronic acid dermal fillers (ESTYME FILLERS range), silicone gel-filled breast implants (ESTYME MATRIX using PRYME FEM technology), and a bi-layer collagen-silicone dermal regeneration matrix (NEVELIA) for burns, chronic wounds and reconstructive surgery. The company also exclusively distributes Black & Black Surgical plastic surgery instruments in France. Products are sold to plastic surgeons, dermatologists, cosmetic physicians, burn and wound care specialists, and medical device distributors worldwide.

Product overview

SYMATESE AESTHETICS is a MedTech company acting as a pure player in aesthetic medicine and plastic surgery, offering three main product categories: ESTYME® FILLERS (cross-linked hyaluronic acid dermal fillers for facial rejuvenation including ESTYME LIPS, SMOOTH, FORM, and SCULPT), ESTYME® MATRIX (silicone gel-filled breast implants using PRYME® technology), and NEVELIA® (bi-layer collagen-silicone dermal regeneration matrix). The company also distributes Black and Black Surgical instruments. Products target plastic surgeons, dermatologists, and cosmetic physicians for breast surgery, facial rejuvenation, and dermal reconstruction applications.

Differentiator

Problem solved

Functional benefit

Brands

• ESTYME®: Product brand for HA dermal fillers and breast implants including ESTYME® FILLERS (hyaluronic acid dermal fillers) and ESTYME® MATRIX (breast implants)
• NEVELIA®
• ESTYME® FILLERS
• ESTYME® MATRIX
• PRYME®

Products and services

• ESTYME FILLERS Cross-linked hyaluronic acid (HA) dermal fillers indicated for facial rejuvenation including wrinkles treatment, mid-face volume restoration, and lips volume correction. The range contains lidocaine for patient comfort and is CE marked under EU MDR 2017/745. Sub-products include ESTYME LIPS, ESTYME SMOOTH, ESTYME FORM, and ESTYME SCULPT, each targeting specific indications.
• ESTYME MATRIX Silicone gel-filled breast implants indicated for breast augmentation and breast reconstruction following cancer or injury, and treatment of severe breast abnormality. Designed using PRYME Finite Elements Modeling (FEM) technology that predicts shell stress, gel flow, and implant deformation. Manufactured with FDA-approved long-term biocompatible polydimethylsiloxane (PDMS) with controlled viscosity and cohesivity.
• NEVELIA Bi-layer dermal regeneration matrix consisting of a three-dimensional porous matrix of stabilized bovine origin type I collagen combined with a reinforced silicone pseudo-epidermis layer. Used for dermal reconstruction following skin loss in 3rd degree burns, deep 2nd degree burns, chronic wounds, traumatology, and skin cancer reconstruction. The collagen matrix has optimal hydrophily, pore structure, and cross-linking for neodermis formation, and the silicone layer provides immediate waterproofing, mechanical protection, and antibacterial barrier.
• Black & Black Surgical Instruments

Quantifiable outcome

• 0% capsular contracture, 0% rupture, and 0% explantation in the EMMIE study with 24 patients and 46 micro-textured round breast implants at 2 years.
• +4 more outcomes

Named customers7 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Five partnerships are on record, tiered core and minor.

• L'OréalcoreStrategic or Co-development PartnerL'Oréal and Symatese strengthened their strategic research partnership on biomaterials in 2021, building on Symatese's recognized quality and expertise in collagen and silicone technologies by leading cosmetics and dermatology brands.
• Black & Black Surgical, Inc.coreChannel Partner/ Reseller/ DistributorSYMATESE AESTHETICS is the exclusive distributor of Black & Black Surgical premium plastic surgery instruments in France. Black & Black Surgical, created in 2007, is the premier USA Instrument Supply company for plastic, reconstructive and aesthetic surgery including breast, rhinoplasty, face lift, liposuction, and lipofilling. They have worked alongside renowned surgeons including Tebbett's, Gorney, Ramirez, Daniels, and Aston.
• Global Leaders from Aesthetic IndustryminorStrategic or Co-development PartnerPlastic surgeons, dermatologists, and other medical specialists, as well as global leaders from the aesthetic industry partner with SYMATESE AESTHETICS for product development and market access.
• SYMATESE LATAMcoreStrategic or Co-development PartnerSYMATESE LATAM is a subsidiary established in Sao Paulo, Brazil in 2016, managing Latin American operations including distribution of NEVELIA products and compliance with ANVISA regulatory requirements.
• SYMATESE (Parent Group)coreStrategic or Co-development PartnerSYMATESE AESTHETICS is part of the Symatese group which brings together the parent company and affiliates (symatese.com, symatese-device.com, symatesecn.com, symateselatam.com.br). The parent group provides technology platforms including acid hyaluronic, collagens, and thermoplastics that SYMATESE AESTHETICS combines with its silicone expertise.

Scale indicators9 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• Mentor (Johnson & Johnson): Johnson & Johnson's breast implant and aesthetics division with decades of experience in silicone gel-filled breast implants. Competes with ESTYME MATRIX across global markets.
• Allergan Aesthetics (AbbVie): Aesthetics arm of AbbVie offering JUVÉDERM HA dermal fillers, breast implants, BOTOX, and body contouring. Directly competes with Symatese Aesthetics across all three product categories but at vastly greater scale and global reach.

Others

• L'Oréal (Active Cosmetics Division): Both strategic partner and adjacent player to Symatese Aesthetics through dermatological skincare brands (La Roche-Posay, CeraVe, SkinCeuticals). Relevant as both an upstream collaborator on biomaterials and downstream competitor in the broader aesthetics market.

Direct peers

• Galderma: Dermatology-focused MedTech with the Restylane HA dermal filler portfolio and Sculptra biostimulator. Closely comparable to Symatese Aesthetics' ESTYME FILLERS range in target customers, indications, and technology platform.
• GC Aesthetics: Medical device company offering silicone breast implants (PERLE, GLOW) for aesthetic and reconstructive surgery. Direct competitor to Symatese Aesthetics' ESTYME MATRIX in the breast implant category.
• Establishment Labs: Public medical technology company focused on breast implants (Motiva) with FDA approval recently secured. Direct competitor to ESTYME MATRIX in silicone gel-filled breast implants targeting premium plastic surgery customers.
• Integra LifeSciences: Public medical technology company offering regenerative tissue technologies including dermal matrices (Integra Dermal Regeneration Template) for burns and wound reconstruction. Most direct peer to NEVELIA's dermal regeneration matrix franchise.
• Sinclair Pharma: Aesthetic medicine company with HA fillers, biostimulators, and Ellansé. Comparable peer given similar mid-sized positioning and overlapping channel strategy in plastic surgery and dermatology.
• Merz Aesthetics: Specialty aesthetics business offering Belotero HA fillers, Radiesse biostimulators, and Ultherapy. Competes head-to-head with ESTYME FILLERS in physician-dispensed facial rejuvenation channels.
• Teoxane: French-influenced Swiss aesthetics company specializing in HA dermal fillers (TEOSYAL range). Closely comparable mid-sized competitor to Symatese's ESTYME FILLERS line in physician offices and dermatology channels.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/symatese-aesthetics

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SYMATESE AESTHETICS