The LOOP Zurich
The LOOP Zurich is a Swiss non-profit translational research consortium linking ETH Zurich, University of Zurich, and four Zurich university hospitals to advance precision medicine. It operates the LOOP BMIP shared biomedical informatics platform and funds multi-institutional translational projects in oncology, neurology, obesity, and infectious disease.
- Company typePrivate
- Founded2020
- HeadquartersZürich, Switzerland
- Headcount51–100
- GTM typeB2B
- OfferingServices
What The LOOP Zurich does
The LOOP Zurich is a Swiss non-profit translational research consortium, organized as a simple partnership (Einfache Gesellschaft) under Swiss law, that links the biomedical and bioinformatics capacity of ETH Zurich and the University of Zurich with the clinical research operations of four Zurich university hospitals: University Hospital Zurich (USZ), University Children's Hospital Zurich (KiSpi), Balgrist University Hospital, and the University Hospital of Psychiatry Zurich (PUK). Founded operationally in 2020 and headquartered at Moussonstrasse 15 in Zurich, the organization employs 51–100 staff in its managing office and orchestrates an estimated 18–25 researchers per major project across the six partner institutions. Its mission is to accelerate the translation of molecular and computational discoveries into precision-medicine applications for patient benefit.
The consortium's central technology asset is the LOOP BMIP (Biomedical Informatics Platform), a shared research infrastructure that integrates and harmonizes clinical data from the partner hospitals and universities with interoperability to the national Swiss Personalized Health Network (SPHN). The BMIP is extended by two Platform Projects—POLAR, which pipelines proteomic profiles of lymphomas into clinical reporting, and BMI2, which extends the platform to medical imaging data across radiology, pathology, and radiation oncology. The translational portfolio comprises StimuLOOP (precision sensorimotor neurorehabilitation for stroke and Parkinson's), INTeRCePT (ex vivo drug response profiling to intercept clonal evolution in blood cancers), LOOBesity (molecular and AI-driven personalization of obesity therapy, including a GLP-1 Decision Support System), and mTORUS (microbiome-based therapies for recurrent urinary tract infections). Incubator Projects (AI Tumor Board, PREVENT-SSc) and the cross-institutional Zurich Precision Oncology Consortium (ZPOC) provide a pipeline of new initiatives, with two additional translational projects (ReGenStent in cardiovascular; AU-FUS Brain Networks in neuropharmacology) selected to start in late 2026.
The LOOP Zurich does not sell commercial products or services. It is funded through donations from a concentrated set of Swiss foundations (notably Helmut Horten Foundation, Vontobel-Stiftung, Monique Dornonville de la Cour-Foundation, Uniscientia Foundation, Georg und Berta Schwyzer-Winiker Foundation, and Promedica Foundation) plus competitive internal grant calls (Translational Projects up to CHF 5M over five years; Platform and Incubator Projects up to CHF 1M over three years). Governance comprises a Directorate (Founding Director/CEO Markus Rudin; Co-Director Giatgen Spinas; Managing Director/COO Jens Selige), a Steering Committee with senior representatives from each of the six partner institutions, and an international Scientific Advisory Board. Distribution occurs through peer-reviewed publications (50+ papers including in Nature Cancer, Science, Blood, and Nature Communications), conference presentations (ASH, EHA, ICNR), integration into partner-hospital clinical workflows, annual reports (2023–2025 published), a podcast and YouTube channel, and co-development partnerships with EMBL Heidelberg, EPFL, TU München, IRB Bellinzona, IOR Bellinzona, and cereneo.
The LOOP Zurich firmographics
Firmographics- Name
- The LOOP Zurich
- Legal name
- The LOOP Zurich
- Website
- https://theloopzurich.ch
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- The LOOP Zurich is a Swiss non-profit translational research consortium linking ETH Zurich, University of Zurich, and four Zurich university hospitals to advance precision medicine. It operates the LOOP BMIP shared biomedical informatics platform and funds multi-institutional translational projects in oncology, neurology, obesity, and infectious disease.
- Ownership category
- akta.pro rank
The LOOP Zurich industry classification
Industry- Product category
- Translational Research
- NAICS
- Scientific Research and Development Services (5417), Research and Development in the Physical, Engineering, and Life Sciences (54171), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Translational Medicine & Biomarkers (HLAIALAF)
- akta.pro secondary industries
- Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM), Biostatistics, Statistical Computing & Clinical Programming (SAS/R/Pipelines) (HLACAOAO), Precision Clinical Trials Enablement (patient matching, site matching, adaptive trials) (HLAAANAI)
Keywords
Where The LOOP Zurich is headquartered
LocationHeadquarters
- HQ city
- Zürich
- HQ country
- Switzerland
- HQ region
- Europe
Offices1 record
Markets served
The LOOP Zurich business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Infrastructure, Others
Revenue model
- Foundation Funding: The LOOP Zurich operates as a research consortium funded primarily through donations from multiple foundations supporting precision medicine research and development.
- Project Grants: Funding through competitive grant calls: Platform Projects (max CHF 1 million over 3 years), Translational Projects (up to CHF 5 million over 5 years), Incubator Projects (max CHF 1 million over 3 years).
Go-to-market motion2 records
Distribution channels1 record
Marketing channels8 records
The LOOP Zurich product offering
Product offeringCore offering
The LOOP Zurich operates as a translational research consortium that develops and operates the LOOP BMIP biomedical informatics platform, integrating clinical data from Zurich's university hospitals for data-driven precision medicine research. It delivers this through three program tracks: Platform Projects (BMI2 imaging, POLAR proteomics), Translational Projects (INTeRCePT blood cancer, StimuLOOP neurorehabilitation, LOOBesity obesity, mTORUS urinary tract infections), and Incubator Projects (AI Tumor Board, PREVENT-SSc), combined with the ZPOC oncology consortium. All outputs are research capabilities used by partner institutions rather than commercial products sold externally.
Product overview
The LOOP Zurich operates as a translational research center focused on precision medicine, connecting biomedical research and bioinformatics from ETH Zurich and University of Zurich with clinical research from four university hospitals. Its core product is the LOOP BMIP (Biomedical Informatics Platform), a shared research infrastructure that consolidates clinical data and supports data-driven research. The portfolio includes Platform Projects (BMI2 for imaging integration, POLAR for proteomics), Translational Projects (INTeRCePT for blood cancer, StimuLOOP for neurorehabilitation, LOOBesity for obesity treatment, mTORUS for urinary infections), and Incubator Projects (AI Tumor Board for oncology decision support). ZPOC coordinates precision oncology across institutions. All offerings are research-focused rather than commercial products.
Differentiator
Problem solved
Functional benefit
Products and services
- LOOP BMIP (Biomedical Informatics Platform) Shared research infrastructure that integrates, stores, and harmonizes clinical data from Zurich's university hospitals and makes it accessible for interdisciplinary, data-driven research in precision medicine, with SPHN interoperability.
- BMI2 (Biomedical Informatics Imaging Platform) SPHN-compatible extension of LOOP BMIP that integrates medical imaging data from radiology, pathology, radiation oncology, and other disciplines, making it available for AI-supported analysis and research.
- POLAR (ProteOmics for Lymphoma and Prognostication) Workflow and analysis pipeline that integrates lymphoma proteomes into the LOOP BMIP for diagnosis, identifying treatment targets, and assessing drug effectiveness, supported by the Uniscientia Foundation.
- INTeRCePT (Intercepting Clonal Evolution in Blood Cancers) Translational project developing an ex vivo drug testing program and INTeRCePT Assay for personalized treatment optimization in hematologic malignancies, with the goal of increasing patient therapy response rates by 50%.
- StimuLOOP (Precision Sensorimotor Neurorehabilitation) Translational project developing personalized stimulation loops using visual feedback, acoustic stimulation, and EEG-synchronized sleep stimulation for precision neurorehabilitation of stroke and Parkinson's patients.
- LOOBesity (Precision Medicine in Obesity) Translational project advancing precision medicine in obesity by integrating molecular, imaging, and AI-driven analyses to develop personalized therapies for individuals with altered glucocorticoid metabolism.
- mTORUS (Microbiome Therapy for Recurrent Urinary Tract Infections) Microbiome-based therapeutic project developing treatment options for recurrent urinary tract infections through bacteriophage elimination and microbiome transplantation, supported by the Monique Dornonville de la Cour-Foundation.
- AI Tumor Board (Personalized Decision Support in Precision Oncology) AI-powered platform providing oncologists with evidence-based treatment recommendations by aligning patient data with medical guidelines and analyzing historical treatment outcomes in precision oncology.
- ZPOC (Zurich Precision Oncology Consortium) Jointly selected consortium by CCCZ, TPC, and The LOOP Zurich that supports interdisciplinary teams developing innovative diagnostic and therapeutic approaches for precision oncology.
Quantifiable outcome
- Goal to increase patient therapy response rates by 50% through INTeRCePT precision oncology approach
- +4 more outcomes
Companies that use The LOOP Zurich
Customer profileNamed customers6 records
Segments4 records
Ideal customer profiles3 records
The LOOP Zurich technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
The LOOP Zurich partnerships and signals
Strategic signalPartnerships
Six partnerships are on record, tiered core and supporting.
- EMBL HeidelbergcoreInternational research partner contributing to INTeRCePT blood cancer project. Prof. Wolfgang Huber from EMBL leads quantitative biology and statistics work package.
- cereneosupportingNeurorehabilitation clinic in Vitznau collaborating on StimuLOOP project development and knowledge exchange.
- EPFLsupportingSwiss technical university partner in mTORUS project contributing to microbiome research.
- TU MünchensupportingTechnical University of Munich collaborating partner in LOOBesity obesity research project.
- Institute for Research in Biomedicine (IRB Bellinzona)supportingTicino-based research institution collaborating on Helmut Horten Anniversary Project extending INTeRCePT to rare lymphomas research.
- Institute of Oncology Research (IOR Bellinzona)supportingTicino-based oncology research institution partnering on Helmut Horten Anniversary Project for precision medicine in lymphoma.
Scale indicators16 records
Recent moves6 records
Expansion highlights6 records
The LOOP Zurich competitors and assessment
Company assessmentDirect peers
- Broad Institute of MIT and Harvard: Major U.S. biomedical research institute focused on genomics, precision medicine, and translational science with multi-institutional academic anchoring. Operates a comparable model of integrating computational biology with clinical research across partner hospitals.
- Wellcome Sanger Institute: Genome and biomedical research institute with foundation funding (Wellcome Trust) focused on translational genomics and precision medicine. Similar in combining large-scale data infrastructure with translational projects targeting specific disease areas.
- Allen Institute: Non-profit medical research organization focused on large-scale science programs with multi-institutional collaboration and substantial foundation funding. Similar structure of operating major research programs with shared data infrastructure and high-impact publication output.
- Francis Crick Institute: U.K.-based biomedical discovery institute with multi-institutional academic affiliation focused on translational research. Comparable scale and partnership structure bringing together basic and clinical research under one organizational umbrella.
- MD Anderson Moon Shots Program: Large-scale precision oncology translational initiative within MD Anderson Cancer Center. Directly comparable to INTeRCePT and ZPOC projects in scope of multi-project, multi-institutional precision cancer research with strong foundation/philanthropic backing.
- Berlin Institute of Health (BIH): Translational research consortium at Charité and Max Delbrück Center, also bridging university hospitals with biomedical research. Operates a similar precision medicine and clinical translation model funded by German federal and state governments.
- Icahn Institute for Genomics and Multiscale Biology: Translational genomics institute within Mount Sinai Health System focused on precision medicine and biomedical informatics. Comparable focus on AI/ML-driven clinical research and integration of hospital data with research platforms.
- National Center for Tumor Diseases (NCT): German translational oncology consortium integrating multiple university hospitals with research institutions. Direct peer in structure of cross-institutional translational precision oncology research with foundation and government funding.
- Swiss Institute of Bioinformatics (SIB): Swiss national bioinformatics organization coordinating data infrastructure and computational biology across Swiss academic institutions. Closest peer to The LOOP Zurich's LOOP BMIP platform component and SPHN interoperability mission.
Regional players
- SciLifeLab: Swedish national molecular life sciences consortium distributed across multiple universities, providing shared technology platforms and data infrastructure. Comparable consortium model operating across national academic and hospital partners for life science research.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
The LOOP Zurich social profiles
Digital presenceThe LOOP Zurich financial estimates
Financial estimateRevenue estimate
Valuation estimate
The LOOP Zurich leadership team
Management profileNumber of profiles
Profiles18 records
The LOOP Zurich funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
The LOOP Zurich M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about The LOOP Zurich
What does The LOOP Zurich do?
The LOOP Zurich operates as a translational research consortium that develops and operates the LOOP BMIP biomedical informatics platform, integrating clinical data from Zurich's university hospitals for data-driven precision medicine research. It delivers this through three program tracks: Platform Projects (BMI2 imaging, POLAR proteomics), Translational Projects (INTeRCePT blood cancer, StimuLOOP neurorehabilitation, LOOBesity obesity, mTORUS urinary tract infections), and Incubator Projects (AI Tumor Board, PREVENT-SSc), combined with the ZPOC oncology consortium. All outputs are research capabilities used by partner institutions rather than commercial products sold externally.
Is The LOOP Zurich a public or private company?
The LOOP Zurich is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was The LOOP Zurich founded?
The LOOP Zurich was founded in 2020. It employs 51 to 100 people.
Where is The LOOP Zurich based?
The LOOP Zurich is headquartered in Zürich, Switzerland, in the Europe region.
How does The LOOP Zurich make money?
Two revenue lines are on record. Foundation Funding is the primary driver. The others are project Grants.
Who are The LOOP Zurich's main competitors?
Direct peers on record are Broad Institute of MIT and Harvard, Wellcome Sanger Institute, Allen Institute, Francis Crick Institute, MD Anderson Moon Shots Program, Berlin Institute of Health (BIH), Icahn Institute for Genomics and Multiscale Biology, National Center for Tumor Diseases (NCT) and Swiss Institute of Bioinformatics (SIB). SciLifeLab is listed as a regional player.
Does The LOOP Zurich have an API?
No public API is recorded for The LOOP Zurich.
What industry is The LOOP Zurich in?
The LOOP Zurich's product category is Translational Research. Its primary akta.pro industry code is HLAIALAF, Translational Medicine & Biomarkers, with a secondary code of HLAGAJAM, Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF). Its NAICS code is 5417 and its SIC code is 8731.