Society for Inherited Metabolic Disorders

What Society for Inherited Metabolic Disorders does

The Society for Inherited Metabolic Disorders (SIMD) is a 501(c)(3) nonprofit professional society founded in 1978 and headquartered in the United States, dedicated to advancing research, education, and clinical care for inborn errors of metabolism (IEM). Its members are physicians, biochemical geneticists, metabolic dietitians, genetic counselors, laboratorians, and basic/clinical researchers who apply for admission and are approved by member vote. SIMD operates through a Board of Directors (President, President-Elect, Past President, Treasurer, Secretary, Directors-at-Large, and committee chairs) with a new Executive Director (Kristi S. Wees, appointed January 2025) leading day-to-day operations; Leslie Lublink serves as consultant and the Secretariat is hosted at Duke University.

SIMD's core product surface consists of educational and clinical resources rather than commercial technology: the North American Metabolic Academy (NAMA) with over 70 PowerPoint lectures hosted at simdnama.org; the Medical Biochemical Genetics Clinical Core Seminar Series (MBG-CCSS) originating at the University of Colorado Anschutz Medical Campus and distributed via YouTube; IEMbase (freely available at iembase.org) and the Case Database of Inherited Metabolic Disorders (CDB-IMD at imd-casesdatabase.org) for browsing and case sharing; the official journal Molecular Genetics and Metabolism published via Elsevier/ScienceDirect; specialty-bucketed online discussion groups; an awards program (Emmanuel Shapira Award, Buist Founders' Award, SIMD-Hyperion Fellowship, JSIMD Young Investigator Presentation Award); and annual plus ad-hoc virtual programming (Expert Webinars, Fellow Journal Club, FDA/SIMD joint webinars, Laboratory Workgroup Webinar Series).

Revenue mechanics combine annual membership dues tiered from $45 (developing-nation trainee) to $295 (regular and affiliate), annual scientific meeting registration with rotating locations (2024 Charlotte co-located with GMDI; 2027 Tucson; ICIEM 2029 Toronto), pharmaceutical sponsorships at Diamond through Bronze levels (Amgen, BioMarin, PTC Therapeutics, Ultragenyx as core supporters), and Elsevier journal distribution. Financial details are not publicly disclosed (FY2007 fund balance was approximately $316K including a $160K restricted NAMA account). The society maintains formal collaborations with ACMG, GMDI, ICIEM, SSIEM, JSIMD, and FDA/Office of New Drugs, and engages in public-policy advocacy on newborn screening, ACHDNC, and medical foods.

Name

Society for Inherited Metabolic Disorders

Legal name

Society for Inherited Metabolic Disorders

Website

https://simd.org

Company type

Private

Founded year

1978

Operating status

Operating

Headcount range

51–100 employees

Short description

The Society for Inherited Metabolic Disorders (SIMD) is a US 501(c)(3) nonprofit professional society founded in 1978 that serves metabolic medicine physicians, biochemical geneticists, dietitians, genetic counselors, and researchers through education (NAMA, MBG-CCSS), its journal Molecular Genetics and Metabolism, annual meetings, and policy advocacy on newborn screening and rare metabolic disorders.

Ownership category

akta.pro rank

Product category

Professional Medical Association

NAICS

Professional Organizations (81392)

akta.pro primary industry

Genetic & Genomic Rare Disease Therapeutics (HLAIAIAA)

Keywords

• Professional Medical Society
• Inherited Metabolic Disorders
• Medical Education Programs
• Metabolic Disease Research
• Biochemical Genetics Training

Headquarters

HQ city

West Linn

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Membership Dues: Annual dues from members form the primary recurring revenue stream. Dues categories include Regular ($295/yr), Non-Doctoral ($130/yr), Trainee ($130/yr up to 3 years), Affiliate ($295/yr), Emeritus ($0-$95/yr), and Developing Nation ($130/yr or $45/yr for trainees). Dues are invoiced annually in May or June.
2. Annual Meeting Registration: Registration fees for annual scientific meetings. Meetings frequently co-locate with ACMG, GMDI, or international ICIEM events, generating additional registration revenue. Pharmaceutical company sponsors provide financial support at various levels (Diamond, Platinum, Gold, Silver, Bronze).
3. Journal Subscription: Annual subscription to Molecular Genetics and Metabolism is included in membership dues (except for Emeritus without MGM option). Individual online access and subscription changes handled through Elsevier.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels6 records

Core offering

The Society for Inherited Metabolic Disorders (SIMD) is a 501(c)(3) nonprofit professional society that serves clinicians, scientists, genetic counselors, dietitians, and trainees working in inherited metabolic disorders. It delivers educational programs such as the North American Metabolic Academy (NAMA) and the MBG-CCSS seminar series, operates knowledgebases including IEMbase and the Case Database of Inherited Metabolic Disorders (CDB-IMD), publishes the Molecular Genetics and Metabolism journal, and convenes its Annual Scientific Meeting. SIMD also advocates for the field through policy engagement and partnerships with ACGME, ACIMD, ABMGG, JSIMD, the Gemon Foundation, and NORD.

Product overview

SIMD is a professional organization that provides educational resources, publications, and member services for professionals in inherited metabolic disorders. Its core offerings include the North American Metabolic Academy (NAMA) with over 70 PowerPoint presentations, the Medical Biochemical Genetics Clinical Core Seminar Series (MBG-CCSS), and the Molecular Genetics and Metabolism journal as its official publication. Additional services include discussion groups organized by professional category (Clinicians, Dietitians, Nurses, Laboratorians, Counselors, Basic/Clinical Research), an awards program recognizing excellence in the field, and access to knowledgebases including IEMbase and the Case Database of Inherited Metabolic Disorders.

Differentiator

Problem solved

Functional benefit

Products and services

• North American Metabolic Academy (NAMA) Formal education program providing specialized training in inherited metabolic disorders for clinicians, scientists, genetic counselors, and dietitians
• MBG-CCSS Seminar Series Regular seminar series for metabolic disease specialists delivered through SIMD's online educational platform
• IEMbase Specialized knowledgebase for inherited metabolic disorders used by metabolic disease professionals
• Case Database of Inherited Metabolic Disorders (CDB-IMD) Case database of inherited metabolic disorders with an Aggregated website for case submissions and reference
• Annual Scientific Meeting SIMD's annual scientific meeting for metabolic disease clinicians, researchers, and trainees, supported by Diamond, Platinum, Gold, Silver, and Bronze sponsors
• Molecular Genetics and Metabolism Journal Peer-reviewed scientific journal published in partnership with Elsevier, focused on molecular genetics and metabolism research
• Discussion Groups Platform Member-only online discussion groups for peer collaboration among SIMD members
• SIMD Awards Program Society awards recognizing contributions to the inherited metabolic disorders field

Quantifiable outcome

• NAMA offers >70 professional educational presentations covering broad range of metabolic disease topics
• +2 more outcomes

Named customers5 records

Segments5 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• American College of Medical Genetics and Genomics (ACMG)coreStrategic or Co-development PartnerSIMD holds joint sessions with ACMG at annual meetings. 2023 meeting co-located with ACMG in Salt Lake City. 2019 meeting featured joint session in Seattle with ACMG. Ongoing collaboration on meetings and policy.
• Genetic Metabolic Dietitians International (GMDI)coreStrategic or Co-development PartnerSIMD2024 annual meeting held in conjunction with GMDI annual meeting immediately following SIMD meeting in Charlotte. Joint sessions and shared attendance.
• International Congress of Inborn Errors of Metabolism (ICIEM)coreStrategic or Co-development PartnerSIMD co-hosts ICIEM meetings approximately every 4 years. Past: 2013 Barcelona, 2017 Rio de Janeiro. Upcoming: 2029 Toronto. SIMD provides travel awards for trainees to attend.
• SSIEM (Society for the Study of Inborn Errors of Metabolism)coreStrategic or Co-development PartnerSSIEM holds annual meetings in Europe. SIMD lists SSIEM events (2026 Helsinki, 2027 Dublin, 2030 Basel) on meetings page. International collaboration on metabolic disorder research.
• Japanese Society for Inherited Metabolic Disorders (JSIMD)minorStrategic or Co-development PartnerEstablished 2019 JSIMD Young Investigator Presentation award to bring JSIMD-selected young investigator to SIMD annual meeting. Collaborative recognition of trainees.
• U.S. FDA/Office of New Drugs (OND)minorStrategic or Co-development PartnerListed as Non-Commercial/Parent Support Group supporter of SIMD2024. FDA/SIMD Webinars on regulatory perspectives including clinical outcome assessments in clinical trials for IEM.
• Children's Hospital of Philadelphia (CHOP)minorStrategic or Co-development PartnerNon-Commercial supporter of SIMD2024. CHOP faculty participate in SIMD education including MBG-CCSS lectures and award recipients.
• National PKU AllianceminorStrategic or Co-development PartnerNon-Commercial/Parent Support Group supporter of SIMD2024. Represents patient community for phenylketonuria.
• United Mitochondrial Disease FoundationminorStrategic or Co-development PartnerNon-Commercial supporter of SIMD2024. Patient advocacy organization for mitochondrial disorders.

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Japanese Society for Inherited Metabolic Disorders (JSIMD): National counterpart IEM society. SIMD and JSIMD jointly administer the Young Investigator Presentation Award since 2019, demonstrating formal cross-border peer collaboration on trainee recognition.
• International Congress of Inborn Errors of Metabolism (ICIEM): Quadrennial international IEM congress co-hosted by SIMD with SSIEM and other societies. Serves the same clinician-researcher audience as SIMD's annual meeting but at global scale (2029 Toronto upcoming).
• Genetic Metabolic Dietitians International (GMDI): Co-locates annual meetings with SIMD (most recently Charlotte 2024) and serves the dietitian segment of the IEM professional community. Closest operational peer with shared audience and educational programming.
• Society for the Study of Inborn Errors of Metabolism (SSIEM): European/international IEM society with parallel mission, membership model, and annual meeting structure. SIMD cross-lists SSIEM events on its meetings page, indicating tight functional equivalence as a sister society.

Others

• Association for Molecular Pathology (AMP): Society for molecular pathology professionals including biochemical genetics laboratorians — a SIMD member category. Adjacent specialty with shared laboratory audience but different primary focus.
• National PKU Alliance (NPKUA): Patient advocacy organization for phenylketonuria, a core SIMD disease area. Listed as a Non-Commercial supporter of SIMD2024. Adjacent ecosystem participant rather than direct competitor.

Emerging players

• National Society of Genetic Counselors (NSGC): U.S. society for genetic counselors — a segment SIMD serves through its dedicated Counselor discussion group. Partial overlap on IEM clinical topics but distinct professional identity.

Broad incumbents

• American Society of Human Genetics (ASHG): Largest U.S. human genetics society with annual meeting drawing 8,000+ attendees. Many SIMD members also attend ASHG; broader scope includes IEM but lacks SIMD's clinical specialty focus.
• European Society of Human Genetics (ESHG): European counterpart to ASHG. Similar broader society model with overlapping IEM basic-research content but different geographic focus than SIMD.
• American College of Medical Genetics and Genomics (ACMG): Larger medical genetics professional society (3,000+ members) that co-hosts joint sessions with SIMD (Salt Lake City 2023, Seattle 2019). Broader mandate captures overlapping IEM content but lacks SIMD's specialty depth.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/@SIMD_Metabolic
• Facebookfacebook.com/profile.php
• LinkedInlinkedin.com/company/society-for-inherited-metabolic-disorders

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Society for Inherited Metabolic Disorders