Children's Brain Tumor Network
Children's Brain Tumor Network is a nonprofit pediatric brain tumor research consortium spanning 35 institutions across 9 countries, operating a data commons, AI platform, and biosample repository serving academic researchers, pharmaceutical partners, and government precision-medicine programs.
- Company typePrivate
- Founded2011
- HeadquartersPhiladelphia, United States
- Headcount51–100
- GTM typeB2B
- OfferingServices
What Children's Brain Tumor Network does
Children's Brain Tumor Network (CBTN) is a nonprofit pediatric brain tumor research consortium founded in 2011 and headquartered within the Children's Hospital of Philadelphia (CHOP) at the Department of Biomedical and Health Informatics (D3b). The consortium operates a multi-institutional collaboration spanning 35 member institutions across 9 countries, engaging over 1,000 investigators and supporting more than 8,000 enrolled patient participants and 85,000+ curated biosamples. CBTN sustains 442+ active research projects and a publication record of 220+ peer-reviewed outputs, positioning itself as one of the largest dedicated pediatric brain tumor research data commons globally.
CBTN's core technology stack includes the Pediatric Brain Tumor Atlas (PBTA) as its primary data asset, the CAVATICA cloud-based analysis platform that standardizes workflows across consortium members, and the RADIANT AI Platform deployed across 200+ hospitals for automated response assessment in pediatric brain tumors. The consortium's revenue mechanics operate on a hybrid nonprofit model: large government grants (most prominently the $50M ARPA-H Pediatric Care eXpansion award), pharmaceutical sponsored research agreements with AstraZeneca, Bayer, and Chimerix, philanthropic and foundation support (including the recently integrated Bridge To A Cure Foundation), and industry-scale genomic partnerships (notably Illumina for up to 100,000 genomes). Data and analytical tools are provided without cost to academic nonprofit researchers, while pharma partnerships generate sponsored-research revenue.
The organization serves three principal customer segments: academic research institutions participating in the consortium, pharmaceutical and biotech companies requiring pediatric oncology data and translational biomarkers, and government agencies funding pediatric precision medicine initiatives. The recent integration of Bridge To A Cure Foundation extends CBTN's reach into family advocacy and donor networks, adding a downstream clinical-trial-recruitment and fundraising channel that complements its upstream research infrastructure.
Children's Brain Tumor Network firmographics
Firmographics- Name
- Children's Brain Tumor Network
- Legal name
- Children's Brain Tumor Network
- Website
- https://cbtn.org
- Company type
- Private
- Founded year
- 2011
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Children's Brain Tumor Network is a nonprofit pediatric brain tumor research consortium spanning 35 institutions across 9 countries, operating a data commons, AI platform, and biosample repository serving academic researchers, pharmaceutical partners, and government precision-medicine programs.
- Ownership category
- akta.pro rank
Children's Brain Tumor Network industry classification
Industry- Product category
- Pediatric Cancer Research Data & Biospecimen Consortium
- NAICS
- Medical Laboratories (621511)
- SIC
- Services-Medical Laboratories (8071)
- akta.pro primary industry
- Pediatric Neurology (HLAKAIAK)
- akta.pro secondary industries
- Genomics & Next-Generation Sequencing (NGS) Services (HLAGANAA), Pediatrics & Adolescent Therapeutics (Digital) (HLACANAL)
Keywords
Where Children's Brain Tumor Network is headquartered
LocationHeadquarters
- HQ city
- Philadelphia
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Children's Brain Tumor Network business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Infrastructure
Revenue model
- Government Grants and Funding: CBTN receives significant federal funding from NIH, ARPA-H ($50M award for Pediatric Care eXpansion), National Cancer Institute's CCDI, and other U.S. government health agencies to support data infrastructure and research operations.
- Pharmaceutical and Biotechnology Partnerships: Collaborations with pharmaceutical companies (AstraZeneca, Bayer, Chimerix, Jazz, Day One) and biotech firms for drug development, data analysis, and precision medicine enablement. These partnerships help manage complex data and accelerate pediatric brain tumor therapeutic development.
- Foundation and Philanthropic Support: Funding from family foundations (Pediatric Brain Tumor Foundation, Lilabean Foundation, Swifty Foundation, and 20+ others) supporting infrastructure, research projects, and operational sustainability through various giving programs.
- Free Resource Access for Nonprofit Researchers: CBTN provides data, biospecimens, and research resources at no cost to nonprofit researchers, funded by grants and philanthropic support rather than direct revenue from researchers.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Freemium | Annual | Free access for nonprofit research institutions |
Go-to-market motion1 record
Distribution channels5 records
Marketing channels6 records
Children's Brain Tumor Network product offering
Product offeringCore offering
Children's Brain Tumor Network is a global nonprofit research consortium that operates the world's largest open-access pediatric brain tumor data ecosystem, providing researchers with access to 85,000+ biospecimens (tumor samples, cell lines, patient-derived models), AI-enabled analytics platforms, standardized clinical and molecular datasets, and collaborative research infrastructure across dozens of children's hospitals worldwide.
Product overview
CBTN operates as a global research consortium offering an integrated ecosystem of data platforms, AI-powered tools, and research services. The core offering is the Pediatric Brain Tumor Atlas (PBTA), the world's largest childhood brain tumor dataset, accessible through cloud platforms including CAVATICA, dbGaP, and the Kids First Data Resource Center. Key AI capability is RADIANT, a cloud-based AI platform integrating research and clinical data. CBTN Curated products (LGG-BRAF, GFAC Post-Mortem) provide disease-specific research-ready cohorts built on the M3 Approach (Multimodal, Multiomic, Multidisciplinary). Additional offerings include the Preclinical Models Portal for tumoroid and patient-derived models, the Gift from a Child tissue donation program, and structured research resource access with scientific committee review. Data types include clinical data, germline/somatic whole genome sequencing, methylation, RNA-Seq, proteomics, and medical imaging.
Differentiator
Problem solved
Functional benefit
Brands
- RADIANT AI: A cloud-based, AI-enabled platform designed to integrate research and clinical data across a child's care journey, turning discovery into actionable insight at the point of care. Backed by ARPA-H PCX program.
- Pediatric Brain Tumor Atlas (PBTA)
- M3 Approach
Products and services
- Pediatric Brain Tumor Atlas (PBTA)
- RADIANT AI Platform
- CBTN Preclinical Models Portal
- CBTN Curated | LGG-BRAF
- CBTN Curated | GFAC Post-Mortem
- CBTN Research Resources Access Program
- Gift from a Child (GFAC) Tissue Donation Program
- CBTN Scientific Projects Program
- M3 Approach
Quantifiable outcome
- 8,000+ patient & family participants enrolled
- +5 more outcomes
Companies that use Children's Brain Tumor Network
Customer profileNamed customers7 records
Segments4 records
Ideal customer profiles4 records
Children's Brain Tumor Network technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration7 records
AI capability9 records
Feature6 records
Children's Brain Tumor Network partnerships and signals
Strategic signalPartnerships
20 partnerships are on record, tiered core and major.
- IlluminacoreData partnership to advance pediatric cancer and rare disease research, analyzing 100,000 whole genomes from pediatric patients through cloud-based platforms. One of the largest unified genomic datasets ever assembled, made available through the Gabriella Miller Kids First Data Resource Center.
- ARPA-H (Advanced Research Projects Agency for Health)core$50 million award for Pediatric Care eXpansion (PCX) program to scale national pediatric data infrastructure and deploy RADIANT AI platform across 200+ pediatric hospitals. Enables secure, real-time data sharing to deliver AI-driven research insights into patient care.
- Gift from a Child (GFAC)coreGFAC is a family-centered initiative honoring post-mortem pediatric brain tumor tissue donations. CBTN partners with GFAC to make tissue donation possible across most pediatric hospitals in the U.S., with Tissue Navigators guiding families through a compassionate process. The partnership has created the largest postmortem pediatric brain tumor collection in the world.
- Gabriella Miller Kids First Data Resource CentercoreProvides researchers open access to genomic and clinical data to drive discoveries in childhood disease. Houses the CBTN Pediatric Brain Tumor Atlas (PBTA) genomic data. NIH-backed initiative enabling data harmonization and sharing.
- National Cancer Institute's Childhood Cancer Data Initiative (CCDI)coreWorks with CBTN to expand childhood cancer data access and support large-scale precision medicine research. National initiative to aggregate and share childhood cancer data.
- NIH Office of Cancer Clinical Proteomics Research (CPTAC)majorLeverages CBTN as a trusted data site to advance proteogenomic insights into pediatric brain tumors. CBTN proteomic data available through CPTAC Proteomic Data Commons.
- AstraZenecamajorPharmaceutical collaborator supporting CBTN's open-science ecosystem. Partnership vital for managing complex pediatric oncology data and enabling precision medicine drug development.
- BayermajorPharmaceutical partner collaborating on pediatric brain tumor research. Contributes to drug development efforts by accessing CBTN's comprehensive biospecimen and data resources.
- ChimerixmajorBiopharmaceutical company working with CBTN on pediatric brain tumor research, including studies on ONC201/ONC206 efficacy in DMG preclinical models.
- Jazz PharmaceuticalsmajorPharmaceutical collaborator supporting CBTN's research ecosystem for pediatric brain tumor therapeutic development.
- Day One BiopharmaceuticalsmajorBiopharmaceutical company focused on pediatric oncology, partnering with CBTN to advance childhood brain tumor research and drug development.
- Stingray TherapeuticsmajorBiotechnology company collaborating on pediatric brain tumor research, including studies on ENPP1 inhibition in medulloblastoma models.
- AWS (Amazon Web Services)coreCloud infrastructure partner supporting CBTN's open-access platform. Provides scalable cloud computing for managing massive genomic and clinical datasets.
- CAVATICA (Seven Bridges)coreSecure, cloud-based platform for storing, sharing, and analyzing massive genomic datasets. Integrated bioinformatics workflows fuel real-time collaboration across research teams worldwide.
- FlywheelmajorInnovation collaborator providing imaging data management platform. Brings imaging into the data ecosystem, supporting advanced radiomics and AI-powered image analysis.
- VelseramajorTechnology innovation partner supporting the backbone of CBTN's open-access platform for genomic and clinical data management.
- GitHubmajorInnovation collaborator supporting software development and version control for CBTN's open-source research tools and data platforms.
- CelerDatamajorInnovation collaborator supporting data infrastructure for CBTN's cloud-based analytics and research platforms.
- MuleSoftmajorInnovation collaborator providing integration technology supporting CBTN's data ecosystem connectivity and interoperability.
- Children's Hospital of Philadelphia (CHOP) - Center for Data Driven Discovery in Biomedicine (D3b)coreOperations center for CBTN. Houses world's largest pediatric brain and CNS tumor biorepository. Executive oversight team drawn from D3b leadership, with Dr. Adam Resnick serving as Scientific Co-Director of CBTN.
Scale indicators11 records
Recent moves7 records
Expansion highlights5 records
Children's Brain Tumor Network competitors and assessment
Company assessmentDirect peers
- Kids First Data Resource Center Portal: Genomic data portal for childhood cancer and structural birth defects — shares datasets and infrastructure with CBTN. Comparable cloud-based data access model for pediatric cancer researchers.
- cBioPortal (Memorial Sloan Kettering): Open-access platform for visualizing and analyzing large-scale cancer genomic datasets. Direct functional peer of PedcBioPortal that CBTN uses for open-access pediatric cancer data exploration.
- Children's Oncology Group (COG): The world's largest pediatric cancer research consortium, with which CBTN directly integrates via the RADIANT AI rollout through COG's 200+ hospital network. Same basic model (multi-institution pediatric cancer research), same customer base (children's hospitals), same end goal (translational pediatric cancer research).
- Pediatric Brain Tumor Consortium (PBTC): NCI-funded multi-institutional consortium specifically focused on pediatric brain tumor clinical trials and translational research. Directly comparable indication focus, member institution structure, and translational research mandate.
- NCI Childhood Cancer Data Initiative (CCDI): National-scale NCI initiative to aggregate and share childhood cancer data — directly partners with CBTN for large-scale precision medicine work. Overlapping mission, downstream competitive funder positioning.
- St. Jude Children's Research Hospital: Runs its own large pediatric cancer genomics initiatives (e.g., St. Jude CancerSEEK, Pediatric Cancer Genome Project) and houses a major pediatric brain tumor program. Comparable mission and scale in pediatric oncology data and biospecimen generation.
- Gabriella Miller Kids First Data Resource Center: NIH-backed centralized ecosystem for childhood cancer and structural birth defects genomic data — actually houses CBTN's PBTA dataset. Closely aligned platform mission, shared data infrastructure, and joint distribution channel.
Broad incumbents
- TERRA (Broad Institute): Broad Institute's cloud-based genomic analysis platform used across major research consortia. Comparable cloud-based collaborative genomic research platform category as CAVATICA/RADIANT.
- DNAnexus: Commercial cloud genomics platform used by large-scale NIH/precision medicine programs. Provides the underlying technology and infrastructure class that CAVATICA and similar platforms (including CBTN) operate in.
- Seven Bridges (CAVATICA): Provider of the CAVATICA cloud platform through which CBTN data is delivered. Direct technology partner and platform peer in the pediatric/genomic data ecosystem.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Children's Brain Tumor Network social profiles
Digital presenceChildren's Brain Tumor Network compliance and trust
Trust signalCompliance2 records
Children's Brain Tumor Network financial estimates
Financial estimateRevenue estimate
Valuation estimate
Children's Brain Tumor Network leadership team
Management profileNumber of profiles
Profiles7 records
Children's Brain Tumor Network funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Children's Brain Tumor Network M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Children's Brain Tumor Network
What does Children's Brain Tumor Network do?
Children's Brain Tumor Network is a global nonprofit research consortium that operates the world's largest open-access pediatric brain tumor data ecosystem, providing researchers with access to 85,000+ biospecimens (tumor samples, cell lines, patient-derived models), AI-enabled analytics platforms, standardized clinical and molecular datasets, and collaborative research infrastructure across dozens of children's hospitals worldwide.
Is Children's Brain Tumor Network a public or private company?
Children's Brain Tumor Network is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was Children's Brain Tumor Network founded?
Children's Brain Tumor Network was founded in 2011. It employs 51 to 100 people.
Where is Children's Brain Tumor Network based?
Children's Brain Tumor Network is headquartered in Philadelphia, United States, in the North America region.
How does Children's Brain Tumor Network make money?
Four revenue lines are on record. Government Grants and Funding is the primary driver. The others are pharmaceutical and Biotechnology Partnerships, foundation and Philanthropic Support and free Resource Access for Nonprofit Researchers.
Who are Children's Brain Tumor Network's main competitors?
Direct peers on record are Kids First Data Resource Center Portal, cBioPortal (Memorial Sloan Kettering), Children's Oncology Group (COG), Pediatric Brain Tumor Consortium (PBTC), NCI Childhood Cancer Data Initiative (CCDI), St. Jude Children's Research Hospital and Gabriella Miller Kids First Data Resource Center. Broad incumbents are TERRA (Broad Institute), DNAnexus and Seven Bridges (CAVATICA).
Does Children's Brain Tumor Network have an API?
No public API is recorded for Children's Brain Tumor Network.
What industry is Children's Brain Tumor Network in?
Children's Brain Tumor Network's product category is Pediatric Cancer Research Data & Biospecimen Consortium. Its primary akta.pro industry code is HLAKAIAK, Pediatric Neurology, with a secondary code of HLAGANAA, Genomics & Next-Generation Sequencing (NGS) Services. Its NAICS code is 621511 and its SIC code is 8071.