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Cyprotex

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uuid003b4gw

Namestring
Cyprotex
Legal namestring
Cyprotex
Websiteurl
cyprotex.com
Company typeenum
Private
Founded yearint
1999
Descriptiontext

Cyprotex is a UK-based contract research organization (CRO) specializing in preclinical ADME-Tox (absorption, distribution, metabolism, excretion, and toxicology) services for the pharmaceutical, biotechnology, chemical, agrochemical, personal care, cosmetics, and household products industries. The company combines robust in vitro experimental methods with in silico modeling to predict human exposure, clinical efficacy, and toxicological outcomes of drug candidates and chemical compounds. Its service portfolio spans four core areas—ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation—supported by proprietary platforms including eCiphr® Cardio (iPS-derived cardiomyocytes on high-throughput microelectrode arrays for cardiotoxicity assessment), eCiphr® Neuro (primary cortical neurons on MEA for neurotoxicity assessment), and CellCiphr® Premier (high-content screening for drug-induced liver injury prediction). The company also offers 3D microtissue models and a New Approach Methodologies (NAMs) resource hub supporting the 3Rs (Replace, Reduce, Refine) of animal testing.

Cyprotex generates revenue through professional service fees for laboratory testing, in vitro assays, and computational modeling under quote-based, project-scoped engagements. Its go-to-market is primarily sales-led via direct engagement with enterprise clients and expert consultation, supplemented by educational webinars and content marketing (newsletters, scientific guides). The company was founded in 1999, headquartered in Macclesfield, UK, operates with 51–100 employees, and was formerly listed on the London Stock Exchange (ticker CRX) before becoming a wholly-owned business unit of Evotec AG, a Frankfurt-listed global drug discovery company. Strategic partnerships include Scientist.com for webinar distribution and co-marketing arrangements with BIOIVT and HUB Organoids.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
51–100
akta.pro rankint
HeadquartersMacclesfield, United Kingdom
HQ citystring
Macclesfield
HQ countrystring
United Kingdom
HQ regionstring
Europe
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
ADME-Tox services, preclinical research, contract research organization, drug discovery services, physicochemical profiling
Industry1 code
1Preclinical CROs (Discovery/Pharmacology/DMPK)
CodeHLAGAAABPrimaryYes
Product category
Preclinical ADME-Tox Contract Research Services
Social media profiles3 records
GTM motion2 records

Each record includes

Type, Description, Source

Revenue model1 record
1ADME-Tox Testing Services
TypeProfessional Services
Description

Cyprotex provides contract research services to pharmaceutical, biotech, personal care, cosmetics, household products, chemical, and agrochemical industries. Services include ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation. Revenue is generated through service fees for laboratory testing and analysis.

evotec.com
Marketing channels4 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components4 values
Personnel, Operations, Technology or R&D, Infrastructure
GTM typeB2B
B2B
Offering typeServices
Services
Brand1 of 3 records shown
1eCiphr®Cardio
Description

Synchronously beating iPS cell derived cardiomyocytes monitored by high throughput microelectrode array (MEA) for cardiotoxicity assessment and disease modelling.

evotec.com
+2 more records
Core offering1 text field

Cyprotex is a contract research organization (CRO) that delivers preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicology) services to pharmaceutical, biotechnology, personal care, cosmetics, household products, chemical, and agrochemical companies. Its offerings include ADME pharmacokinetics, toxicology/preclinical safety testing, physicochemical profiling, and modeling & simulation, supported by proprietary in silico platforms.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 2 values shown
  • Sensitive and specific prediction of DILI (Drug-Induced Liver Injury) through CellCiphr Premier high content screening
+1 more record
Product overview1 text field

Cyprotex ADME-Tox Solutions, a subsidiary of Evotec, provides a comprehensive suite of drug discovery and preclinical development services organized around four core service areas: ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation. The company enhances prediction of human exposure, clinical efficacy, and toxicological outcomes by combining in vitro methods with in silico technology. Cyprotex serves pharmaceutical, biotech, personal care, cosmetics, household products, and chemical/agrochemical industries. The portfolio includes proprietary technologies such as eCiphr Cardio (iPS-derived cardiomyocyte cardiotoxicity testing), eCiphr Neuro (neuronal activity monitoring), and CellCiphr Premier (high content screening for DILI prediction), along with 3D microtissue models and NAMs (New Approach Methodologies) for human-relevant testing.

Product and service6 records
1ADME Pharmacokinetics Services
CategoryADME-Tox Services
2Toxicology / Preclinical Safety Services
CategoryADME-Tox Services
3Physicochemical Profiling Services
CategoryADME-Tox Services
4Modeling & Simulation Services
CategoryComputational Drug Discovery Services
5eCiphrCardio
CategoryIn Silico Safety Platforms
6eCiphrNeuro
Scale indicator1 record

Each record includes

Type, Value, Description, Source

Partnership4 partners
Strategic tierCoreTypeGTM or Marketing PartnerAnnounced on2026-06-15
Description

Cyprotex participates in expert webinars hosted by Scientist.com, presenting on New Approach Methodologies (NAMs) for drug discovery and development alongside BIOIVT and HUB Organoids. This partnership positions Cyprotex as an industry educational resource for the life science sector.

Strategic tierMinorTypeStrategic or Co-development Partner
Description

Cyprotex co-presents with BIOIVT (BioIVT) on human-relevant models and their applications in drug discovery research workflows.

Strategic tierMinorTypeStrategic or Co-development Partner
Description

Cyprotex co-presents with HUB Organoids on organoid-based screening technologies for drug discovery and development.

Strategic tierCoreTypeOthers
Description

Cyprotex operates as a business unit of Evotec, a global drug discovery and development company. Evotec provides the corporate infrastructure and global reach that supports Cyprotex's ADME-Tox operations.

Recent move5 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Global CRO offering drug discovery and preclinical services including in vitro ADME, DMPK, and safety assessment, overlapping with Cyprotex's preclinical ADME-Tox service lines.

TypeBroad incumbent
Description

Large CRO spun out of Labcorp with preclinical and early development services including ADME and safety assessment, comparable to Cyprotex's offerings but at significantly greater scale.

TypeDirect peer
Description

Eurofins Discovery offers ADME, pharmacology, and toxicology services in vitro and in silico, directly competing with Cyprotex's ADME PK, physicochemical profiling, and mechanistic toxicology offerings.

TypeBroad incumbent
Description

Global contract research organization with a large preclinical and safety assessment segment that directly overlaps with Cyprotex's ADME-Tox and in vitro toxicology offerings, including cardiovascular and neuro safety services.

TypeEmerging player
Description

Specialized CRO providing in vitro and computational toxicology services for pharma, chemical, and consumer product industries, comparable to Cyprotex's CellCiphr and NAMs offerings.

TypeDirect peer
Description

Specialized CRO focused on ADME, drug metabolism, and in vitro toxicology with hepatotoxicity and DILI prediction services, directly comparable to Cyprotex's CellCiphr Premier and ADME PK portfolio.

TypeDirect peer
Description

Preclinical CRO and research models provider offering toxicology, ADME, and safety pharmacology services, comparable to Cyprotex's preclinical focus and chemistry and safety assessment capabilities.

TypeBroad incumbent
Description

Biosafety testing and toxicology services arm of Merck, offering in vitro toxicology and product safety testing that directly competes with Cyprotex's preclinical safety and toxicology services.

TypeOthers
Description

Supplier of human biological specimens and in vitro cell models used in drug discovery, co-presenting partner with Cyprotex on NAMs webinars and an enabler of the same preclinical workflow Cyprotex serves.

TypeBroad incumbent
Description

Large global CRO with comprehensive preclinical services including DMPK, toxicology, and in vitro safety assessment, comparable to Cyprotex as a competing provider of preclinical ADME-Tox services.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat3 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers4 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment4 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
No
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature8 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds1 record

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Cyprotex

Preclinical ADME-Tox Contract Research Servicescyprotex.com

What Cyprotex does

Cyprotex is a UK-based contract research organization (CRO) specializing in preclinical ADME-Tox (absorption, distribution, metabolism, excretion, and toxicology) services for the pharmaceutical, biotechnology, chemical, agrochemical, personal care, cosmetics, and household products industries. The company combines robust in vitro experimental methods with in silico modeling to predict human exposure, clinical efficacy, and toxicological outcomes of drug candidates and chemical compounds. Its service portfolio spans four core areas—ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation—supported by proprietary platforms including eCiphr® Cardio (iPS-derived cardiomyocytes on high-throughput microelectrode arrays for cardiotoxicity assessment), eCiphr® Neuro (primary cortical neurons on MEA for neurotoxicity assessment), and CellCiphr® Premier (high-content screening for drug-induced liver injury prediction). The company also offers 3D microtissue models and a New Approach Methodologies (NAMs) resource hub supporting the 3Rs (Replace, Reduce, Refine) of animal testing.

Cyprotex generates revenue through professional service fees for laboratory testing, in vitro assays, and computational modeling under quote-based, project-scoped engagements. Its go-to-market is primarily sales-led via direct engagement with enterprise clients and expert consultation, supplemented by educational webinars and content marketing (newsletters, scientific guides). The company was founded in 1999, headquartered in Macclesfield, UK, operates with 51–100 employees, and was formerly listed on the London Stock Exchange (ticker CRX) before becoming a wholly-owned business unit of Evotec AG, a Frankfurt-listed global drug discovery company. Strategic partnerships include Scientist.com for webinar distribution and co-marketing arrangements with BIOIVT and HUB Organoids.

Cyprotex firmographics

Firmographics
Name
Cyprotex
Legal name
Cyprotex
Website
https://cyprotex.com
Company type
Private
Founded year
1999
Operating status
Operating
Headcount range
51–100 employees
Ownership category
akta.pro rank

Cyprotex industry classification

Industry
Product category
Preclinical ADME-Tox Contract Research Services
akta.pro primary industry
Preclinical CROs (Discovery/Pharmacology/DMPK) (HLAGAAAB)

Keywords

  • ADME-Tox services
  • Preclinical research
  • Contract research organization
  • Drug discovery services
  • Physicochemical profiling

Where Cyprotex is headquartered

Location

Headquarters

HQ city
Macclesfield
HQ country
United Kingdom
HQ region
Europe

Offices1 record

Markets served

Cyprotex business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Operations, Technology or R&D, Infrastructure

Revenue model

  1. ADME-Tox Testing Services: Cyprotex provides contract research services to pharmaceutical, biotech, personal care, cosmetics, household products, chemical, and agrochemical industries. Services include ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation. Revenue is generated through service fees for laboratory testing and analysis.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels4 records

Cyprotex product offering

Product offering

Core offering

Cyprotex is a contract research organization (CRO) that delivers preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicology) services to pharmaceutical, biotechnology, personal care, cosmetics, household products, chemical, and agrochemical companies. Its offerings include ADME pharmacokinetics, toxicology/preclinical safety testing, physicochemical profiling, and modeling & simulation, supported by proprietary in silico platforms.

Product overview

Cyprotex ADME-Tox Solutions, a subsidiary of Evotec, provides a comprehensive suite of drug discovery and preclinical development services organized around four core service areas: ADME PK, Toxicology/Preclinical Safety, Physicochemical Profiling, and Modeling & Simulation. The company enhances prediction of human exposure, clinical efficacy, and toxicological outcomes by combining in vitro methods with in silico technology. Cyprotex serves pharmaceutical, biotech, personal care, cosmetics, household products, and chemical/agrochemical industries. The portfolio includes proprietary technologies such as eCiphr Cardio (iPS-derived cardiomyocyte cardiotoxicity testing), eCiphr Neuro (neuronal activity monitoring), and CellCiphr Premier (high content screening for DILI prediction), along with 3D microtissue models and NAMs (New Approach Methodologies) for human-relevant testing.

Differentiator

Problem solved

Functional benefit

Brands

  • eCiphr®Cardio: Synchronously beating iPS cell derived cardiomyocytes monitored by high throughput microelectrode array (MEA) for cardiotoxicity assessment and disease modelling.
  • eCiphr®Neuro
  • CellCiphr® Premier

Products and services

  • ADME Pharmacokinetics Services
  • Toxicology / Preclinical Safety Services
  • Physicochemical Profiling Services
  • Modeling & Simulation Services
  • eCiphrCardio
  • eCiphrNeuro

Quantifiable outcome

  • Sensitive and specific prediction of DILI (Drug-Induced Liver Injury) through CellCiphr Premier high content screening
  • +1 more outcomes

Companies that use Cyprotex

Customer profile

Named customers4 records

Segments4 records

Ideal customer profiles2 records

Cyprotex technology and API

Technology

Technology focussed No

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature8 records

Cyprotex partnerships and signals

Strategic signal

Partnerships

Four partnerships are on record, tiered core and minor.

  • Scientist.comcoreGTM or Marketing Partner · 15 June 2026Cyprotex participates in expert webinars hosted by Scientist.com, presenting on New Approach Methodologies (NAMs) for drug discovery and development alongside BIOIVT and HUB Organoids. This partnership positions Cyprotex as an industry educational resource for the life science sector.
  • BIOIVTminorStrategic or Co-development PartnerCyprotex co-presents with BIOIVT (BioIVT) on human-relevant models and their applications in drug discovery research workflows.
  • HUB OrganoidsminorStrategic or Co-development PartnerCyprotex co-presents with HUB Organoids on organoid-based screening technologies for drug discovery and development.
  • EvoteccoreOthersCyprotex operates as a business unit of Evotec, a global drug discovery and development company. Evotec provides the corporate infrastructure and global reach that supports Cyprotex's ADME-Tox operations.

Scale indicators1 record

Recent moves5 records

Expansion highlights4 records

Cyprotex competitors and assessment

Company assessment

Direct peers

  • Pharmaron: Global CRO offering drug discovery and preclinical services including in vitro ADME, DMPK, and safety assessment, overlapping with Cyprotex's preclinical ADME-Tox service lines.
  • Eurofins Discovery: Eurofins Discovery offers ADME, pharmacology, and toxicology services in vitro and in silico, directly competing with Cyprotex's ADME PK, physicochemical profiling, and mechanistic toxicology offerings.
  • SEKISUI XenoTech: Specialized CRO focused on ADME, drug metabolism, and in vitro toxicology with hepatotoxicity and DILI prediction services, directly comparable to Cyprotex's CellCiphr Premier and ADME PK portfolio.
  • Inotiv: Preclinical CRO and research models provider offering toxicology, ADME, and safety pharmacology services, comparable to Cyprotex's preclinical focus and chemistry and safety assessment capabilities.

Broad incumbents

  • Fortrea (formerly Labcorp Drug Development): Large CRO spun out of Labcorp with preclinical and early development services including ADME and safety assessment, comparable to Cyprotex's offerings but at significantly greater scale.
  • Charles River Laboratories: Global contract research organization with a large preclinical and safety assessment segment that directly overlaps with Cyprotex's ADME-Tox and in vitro toxicology offerings, including cardiovascular and neuro safety services.
  • BioReliance (Merck KGaA): Biosafety testing and toxicology services arm of Merck, offering in vitro toxicology and product safety testing that directly competes with Cyprotex's preclinical safety and toxicology services.
  • WuXi AppTec: Large global CRO with comprehensive preclinical services including DMPK, toxicology, and in vitro safety assessment, comparable to Cyprotex as a competing provider of preclinical ADME-Tox services.

Emerging players

  • CeeTox: Specialized CRO providing in vitro and computational toxicology services for pharma, chemical, and consumer product industries, comparable to Cyprotex's CellCiphr and NAMs offerings.

Others

  • BioIVT: Supplier of human biological specimens and in vitro cell models used in drug discovery, co-presenting partner with Cyprotex on NAMs webinars and an enabler of the same preclinical workflow Cyprotex serves.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

Cyprotex social profiles

Digital presence

Cyprotex financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Cyprotex leadership team

Management profile

Number of profiles

Cyprotex funding detail

Funding detail

Funding overview

Funding rounds1 record

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Cyprotex M&A and investment

M&A and investment

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Cyprotex

What does Cyprotex do?

Cyprotex is a contract research organization (CRO) that delivers preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicology) services to pharmaceutical, biotechnology, personal care, cosmetics, household products, chemical, and agrochemical companies. Its offerings include ADME pharmacokinetics, toxicology/preclinical safety testing, physicochemical profiling, and modeling & simulation, supported by proprietary in silico platforms.

Is Cyprotex a public or private company?

Cyprotex is a private company. It is classified as corporate owned and is currently operating.

When was Cyprotex founded?

Cyprotex was founded in 1999. It employs 51 to 100 people.

Where is Cyprotex based?

Cyprotex is headquartered in Macclesfield, United Kingdom, in the Europe region.

How does Cyprotex make money?

One revenue line is on record: ADME-Tox Testing Services.

Who are Cyprotex's main competitors?

Direct peers on record are Pharmaron, Eurofins Discovery, SEKISUI XenoTech and Inotiv. Broad incumbents are Fortrea (formerly Labcorp Drug Development), Charles River Laboratories, BioReliance (Merck KGaA) and WuXi AppTec. CeeTox is listed as an emerging player. BioIVT is listed as an others.

Does Cyprotex have an API?

No public API is recorded for Cyprotex.

What industry is Cyprotex in?

Cyprotex's product category is Preclinical ADME-Tox Contract Research Services. Its primary akta.pro industry code is HLAGAAAB, Preclinical CROs (Discovery/Pharmacology/DMPK).

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Live signals
BglcoMedical Technology Investment BankBGL promotes its Diagnostics, Research Tools & Medical Devices Investment Banking team, highlighting its expertise in capital formation and M&A strategy for industry participants. The firm cites specific advisory roles, including advising Cyprotex PLC on its sale to Evotec and Orthoplastics on its sale to MedPlast. These transactions are presented as examples of the team's capability to execute strategic opportunities for clients.PR NewswireGlobal Non-Animal Alternatives Testing Market Report 2023: Major Players Include MatTek, Cyprotex, Emulate, BioIVT, Bio-Rad Laboratories and GE HealthcareResearchAndMarkets has released the "Non-Animal Alternatives Testing Global Market Report 2023," which projects the global market value to reach $1.78 billion in 2022 with a CAGR of 9.08%. The report identifies key industry players such as MatTek, Cyprotex, and GE Healthcare, while noting that government support drives growth despite regulatory challenges. Major trends highlighted include the adoption of organs-on-chips technology to replace animal testing in pharmaceuticals and other sectors.PR NewswireBrown Gibbons Lang and Company (BGL) Advises in the Sale of Preclinical ADME-Toxicology Services Provider Cyprotex PLCEvotec AG acquired Cyprotex PLC in an all-cash transaction valued at £55.7 million, effective December 15, 2016, with Brown Gibbons Lang & Company serving as the exclusive financial advisor to Cyprotex. The acquisition will enable Evotec to strengthen its drug discovery platform by gaining access to Cyprotex's industrialized ADME-Tox services, including in vitro screening, mechanistic toxicology, and predictive modeling capabilities. Cyprotex, which is listed on London's AIM market, operates facilities in the UK near Manchester and in the US at Watertown, MA and Kalamazoo, MI.