What Incube Labs does

InCube Labs is a private multi-disciplinary life sciences R&D laboratory and incubator founded in 1995 by serial medical entrepreneur Mir Imran and headquartered in San Jose, California, with additional facilities in Milpitas, California (active implantables, neuromodulation, microelectronics, manufacturing co-location with partner Modulus) and San Antonio, Texas (implantable leads manufacturing, drug pumps, drug formulation, cardiac circulatory support). The company conceives, prototypes, and develops breakthrough medical innovations across four technical pillars — implantable devices, drug-device combinations, interventional devices, and novel biomaterials — spanning seven therapeutic areas: urology, gastroenterology, women's health, CNS disorders, orthopedics, metabolic disease, and oncology.

Core technology platforms include the RaniPill oral biologics delivery auto-injection pill (commercialized via spin-out Rani Therapeutics and positioned as the "Holy Grail" of drug delivery), a sacral nerve stimulation system for overactive bladder (Sacramed), a transdermal iron deficiency anemia therapy (Fe3 Medical), an implantable drug-device combination that bypasses the blood-brain barrier to treat gliomas (Theracle), an implantable epilepsy therapy (Neurolink), an atrial fibrillation therapy (CoRhythm), gastrointestinal disorder treatments (Python, Entrack), a remote patient monitoring system (iBridge), and a gastric stimulation system for obesity (Intrapace). The company has filed 900+ patent applications, and Mir Imran personally holds 400+ issued and pending patents.

InCube Labs does not sell products directly to end customers. Its business model is that of a venture incubator: internally identify clinically significant problems, develop and test solutions, form portfolio companies around the most commercially viable ones, fund them through its affiliated venture arm (InCube Ventures) and curated investor portal (VentureHealth), provide manufacturing through co-located partner Modulus (ISO 13485 / ISO 9001 certified for Class III medical devices), and monetize through equity appreciation and exits. To date, InCube has founded 24 life sciences companies and achieved 15 successful exits via acquisition or IPO, with acquirers including Medtronic (PercuSurge, VidaMed), St. Jude Medical (Spinal Modulation), Covidien (NFocus, subsequently Medtronic), Mindray (Zonare), Boston Scientific (Cardiac Pathways), L-3 Communications (SafeView), and Hospira (Physiometrics). Leadership consists of Mir Imran (Chairman & CEO), Phil Morgan (VP, San Antonio; pharma R&D background), and Mike Billig (VP, Regulatory Affairs; CEO of regulatory consultancy Experien Group).

Name

Incube Labs

Legal name

InCube Labs

Website

https://incubelabs.com

Company type

Private

Founded year

1995

Operating status

Operating

Headcount range

51–100 employees

Short description

InCube Labs is a multi-disciplinary life sciences R&D lab and incubator founded in 1995 that conceives, develops, and spins out breakthrough medical device, drug-device combination, and biomaterial innovations across seven therapeutic areas, having founded 24 companies with 15 exits.

Ownership category

akta.pro rank

Headquarters

HQ city

San Antonio

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales

Core offering

InCube Labs is a multi-disciplinary life sciences R&D laboratory and incubator that identifies clinical problems with few or inadequate solutions and develops breakthrough medical innovations across implantable devices, drug-device combinations, interventional devices, and novel biomaterials. The lab progresses commercially viable solutions from research project to portfolio company, supporting product development, clinical trials, regulatory approval, and commercialization. Active portfolio companies include Rani Therapeutics (oral biologics delivery), Sacramed (sacral nerve stimulation), Fe3 Medical (transdermal iron therapy), Neurolink (epilepsy therapy), and Theracle (implantable brain cancer therapy).

Product overview

InCube Labs is a multi-disciplinary life sciences lab and incubator focused on developing and commercializing breakthrough medical innovations. The company operates across multiple therapeutic areas including urology, gastroenterology, women's health, CNS disorders, orthopedics, metabolic disease, and oncology. InCube Labs has founded 24 companies with 15 exits, developing innovations in implantable devices, drug delivery combinations, interventional devices, and novel biomaterials. Key products include Rani Therapeutics (oral biologics delivery via RaniPill), Sacramed (sacral nerve stimulation), Fe3 Medical (transdermal iron therapy), and Theracle (implantable brain cancer treatment). The company also has a network of resources including InCube Ventures, VentureHealth, and manufacturing partner Modulus.

Differentiator

Problem solved

Functional benefit

Products and services

• Rani Therapeutics (RaniPill oral biologics delivery platform) Portfolio company developing the RaniPill, an oral biologics delivery platform capable of delivering a wide range of biologic drugs for the treatment of chronic diseases; positioned as the Holy Grail of drug delivery.
• Sacramed (Sacral Nerve Stimulation for Overactive Bladder) Portfolio company developing a neuromodulation system using sacral nerve stimulation for the treatment of overactive bladder (OAB), a bladder disorder that results in an abnormal urge to urinate.
• Fe3 Medical (Transdermal Iron Deficiency Anemia Therapy) Early-stage portfolio company developing a novel transdermal therapy for treatment of iron deficiency anemia, targeting the 25 million people in the US alone with mild to moderate anemia.
• Neurolink (Epilepsy Therapy) Early-stage portfolio company developing a novel therapy for the treatment of epilepsy using an implantable device, targeting a condition affecting nearly three million Americans.
• Theracle (Implantable Drug-Device for Brain Cancer) Portfolio company developing an implantable drug-device combination therapy for gliomas that bypasses the blood-brain barrier to focus treatment directly at the cancer site, with plans to pursue FDA orphan drug designation and fast-track status.
• CoRhythm (Atrial Fibrillation Therapy) Early-stage portfolio company developing a novel therapy for the treatment of atrial fibrillation.
• Python (Gastrointestinal Disorder Treatments) Portfolio company developing novel treatments for gastrointestinal disorders including post-surgical leaks, bioresorbable devices, and prosthetic implants.
• iBridge (Remote Patient Monitoring) Portfolio company developing a remote patient monitoring system to wirelessly manage patients with active implants for enhanced disease management.
• Intrapace (Gastric Stimulation for Obesity - abiliti system) Portfolio company developing an innovative gastric stimulation product platform for treatment of obesity using the abiliti system.
• Entrack (Crohn's Disease and IBD Treatments) Portfolio company developing novel treatments for gastrointestinal disorders including Crohn's disease and ulcerative colitis, with innovations for IBD diagnosis and inflammation sensing.

Segments1 record

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

One partnership is on record.

• ModuluscoreStrategic or Co-development PartnerTurn-key product development and manufacturing partner specializing in wide range of medical, consumer and industrial products from implantable devices to scientific and medical instruments. ISO 9001:2008 and ISO 13485:2003 certified for Class III medical devices. Co-located with InCube Labs at Milpitas facility. Established in 1972. Assists InCube portfolio companies with prototyping through full scale production.

Scale indicators5 records

Recent moves13 records

Expansion highlights5 records

Direct peers

• Alfred E. Mann Foundation for Scientific Research: Los Angeles-based foundation developing advanced medical devices and implants, including cochlear implants and neuromodulation technologies. Comparable to InCube Labs as a mission-driven organization that incubates and commercializes breakthrough implantable medical devices.
• Fogarty Institute for Innovation: Mountain View, CA-based medical device incubator that mentors and develops early-stage innovators into viable companies targeting unmet clinical needs. Directly comparable to InCube Labs as a Silicon Valley medical device incubator developing breakthrough innovations through portfolio company formation.
• Stanford Byers Center for Biodesign: Stanford University-affiliated program that identifies unmet medical needs, invents new technologies, and spins out medical device and digital health companies. Comparable to InCube Labs in its process of framing clinical problems and developing portfolio companies around novel device solutions.

Peers

• Johnson & Johnson Innovation (JLABS):

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/incube-labs

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries10 records

Funding overview

Funding rounds2 records

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Incube Labs