What Regenera Activa does

Regenera Activa Worldwide S.L. is a Barcelona-based medical device company specializing in regenerative medicine, with its commercial focus on the treatment of androgenetic alopecia (AGA). Founded in 2014 as part of the Remedi Group, the company sells the patented Rigenera Technology platform — comprising the N4SA motorized machine, Sicurstick transmitter, and single-use Rigeneracons consumables — that mechanically disaggregates a small biopsy of the patient's own tissue (typically from the mastoid area) into an injectable autologous micrograft suspension called the AMT Triad. The Triad combines progenitor cells, Human Smart Exosomes (up to 70 billion per session in the 2025 EVO generation), and extracellular matrix, with no laboratory manipulation or culturing step.

The core product is the AMT procedure: a single 30-minute session that produces visible results within roughly three months and can be repeated or combined with hair transplant surgery. The company also markets the Activa Hair professional product line (Tricho6 Technology) and a cosmeceutical range, and has expanded the Rigenera platform into orthopaedics, wound care (including a NATO-validated emergency kit), vitiligo, and skin rejuvenation applications. The most recent platform release is the fourth-generation EVO device, which raises cell viability above 90% and exosome yield by ~50% relative to the previous generation.

Commercially, Regenera Activa operates a B2B sales-led model, selling capital equipment and recurring single-use procedure kits to dermatologists, trichologists, hair transplant surgeons, and aesthetic physicians through an authorized distributor network in 60+ countries. Training and certification programs (10,000+ physicians certified) and 80+ peer-reviewed scientific publications support clinician adoption. Revenue is generated from hardware sales (N4SA system), per-procedure consumable kits, training/certification services, and the Activa Hair product line, with no publicly disclosed pricing or revenue figures.

Name

Regenera Activa

Legal name

Regenera Activa Worldwide S.L.

Website

https://regeneraactiva.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Headquarters

HQ city

Barcelona

HQ country

Spain

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Supply Chain, Technology or R&D, Personnel, Marketing or Sales, Others

Revenue model

1. Medical Device Sales: Regenera Activa sells the Rigenera Technology system consisting of the N4SA machine, Sicurstick transmitter, and Rigeneracons consumables to medical professionals and clinics worldwide through a distributor network. The system is required to perform AMT procedures.
2. AMT Procedure Kits: Single-use disposable kits for autologous micrografting procedures. Each procedure requires the patented Rigeneracons and consumables, generating recurring revenue per treatment session. Medical centers purchase these kits to perform AMT procedures on patients.
3. Training and Certification: The company provides certification programs for medical professionals to become official Regenera Activa Experts. Training includes online webinars, live sessions, and certification pathways for dermatologists and trichologists.
4. Activa Hair Products: Tricho6 Technology-based professional hair loss treatment products sold to healthcare professionals for application in their clinics. Can be used as standalone treatment or in combination with AMT procedures.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels10 records

Core offering

Regenera Activa develops, manufactures, and distributes the Rigenera Technology platform — a CE-marked and FDA-registered medical device system that mechanically fragments small autologous skin biopsies into calibrated micrografts for use in hair restoration and regenerative dermatology procedures. The company sells the Rigenera EVO hardware, single-use sterile consumable kits (Rigeneracons, Sicurstick), AMT procedure kits, the AMT Triad suspension solution, and supporting cosmeceutical and exosome-based products to licensed physicians and clinics worldwide.

Product overview

Regenera Activa is a biotech company specializing in hair follicle regeneration through regenerative medicine. The core offering consists of the patented Rigenera Technology platform and AMT (Autologous Micrografting Technology) procedures. The Rigenera Technology comprises the N4SA machine, Sicurstick transmitter, and Rigeneracons accessories that mechanically process patient tissue to produce AMT Triad solution. The AMT Triad is an injectable suspension of progenitor cells, Human Smart Exosomes, and extracellular matrix. The company also offers Activa Hair, a separate consumer product powered by Tricho6 Technology for broader hair loss treatment. The latest EVO (4th generation) was launched in 2025 with improved specifications including 90%+ cell viability and 70 billion exosomes per session. Additional offerings include Smart Exosomes as a standalone component, cosmeceutical products, and specialized protocols for orthopedics and hair transplant combination treatments.

Differentiator

Problem solved

Functional benefit

Brands

• Activa Hair: A professional hair loss treatment powered by Tricho6 Technology, designed to reactivate the natural hair cycle of follicles. Targets all major causes of hair loss through 6 mechanisms of action.

Products and services

• Rigenera Technology Platform CE-marked and FDA-registered medical device platform that mechanically fragments small autologous skin biopsies into calibrated micrografts for hair restoration and regenerative dermatology. Sold to licensed medical professionals and clinics.
• Rigenera EVO (4th generation device) Fourth-generation evolution of the Rigenera mechanical micrografting device hardware, featuring updated engineering for point-of-care autologous tissue fragmentation. Sold to licensed clinics.
• AMT (Autologous Micrografting Technology) Procedure Standardized clinical procedure protocol using the Rigenera device and single-use kits to deliver autologous micrografting treatments for hair restoration. Performed by certified medical practitioners.
• Rigenera Emergency Kit Specialized emergency-use kit configuration of the Rigenera micrografting system for time-sensitive regenerative applications.
• Activa Hair (consumer & professional line) Cosmeceutical and topical hair treatment product line sold under the Activa Hair brand to medical professionals and end users, supporting hair restoration protocols including Human Smart Exosomes-based and Tricho6 Technology formulations.

Quantifiable outcome

• 450,000+ successful procedures performed worldwide
• +5 more outcomes

Named customers9 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• Remedi GroupcoreOthersRegenera Activa operates as a brand under the Remedi Group umbrella. The company is headquartered in Barcelona and functions as a global biotech brand specializing in hair follicle regeneration through regenerative medicine. As part of the Remedi Group, Regenera Activa benefits from shared corporate resources, group brand positioning, and integrated distribution networks across 60+ countries.
• Human Brain Wave (Italy)coreStrategic or Co-development PartnerHuman Brain Wave was founded in Italy in 2012 for the fabrication and distribution of Rigenera® technology. The company collaborates with Regenera Activa for the Italian and Spanish markets initially, and has developed the Rigenera® Emergency Kit for military and civilian emergencies. This long-standing partnership since 2012 has enabled continuous technology development and global expansion of the AMT protocols.

Scale indicators9 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Aderans Company: Aderans is a Japanese company that pioneered cell-based hair regeneration therapy (using autologous hair follicle cells) and operates a global hair restoration business. It is one of the longest-standing direct competitors in regenerative hair medicine with parallel technology ambitions to Regenera Activa's AMT.
• RepliCel Life Sciences: RepliCel develops RCH-01, a dermal sheath cup cell-based autologous cell therapy for androgenetic alopecia. It is a direct competitor to Regenera Activa in autologous regenerative hair treatments, targeting the same patient population and physician specialty channels with a cell-isolation rather than mechanical-disaggregation approach.
• Histogen Inc: Histogen is a regenerative medicine company developing HSC (Hair Stimulating Complex), a proprietary cell-conditioned media treatment for androgenetic alopecia. It directly competes with Regenera Activa's AMT in the physician-administered hair regeneration category, targeting the same dermatologist and trichologist customer base with a non-autologous regenerative approach.

Emerging players

• Stemson Therapeutics: Stemson Therapeutics is an iPSC-based regenerative medicine company focused on engineering hair follicle cells for hair loss treatment. It is an emerging next-generation competitor to Regenera Activa, pursuing an off-the-shelf cell therapy approach that could disrupt the autologous micrografting category if it reaches commercialization.
• Follica Inc: Follica is a clinical-stage company developing a device-plus-molecule protocol to induce hair follicle neogenesis. It overlaps with Regenera Activa's hair regeneration mission but uses a different mechanism (de novo follicle induction) and serves the same dermatologist channel.
• HairClone: HairClone is a UK-based company offering hair follicle cell banking and expansion services for future autologous transplantation. It is an emerging direct competitor in the regenerative hair loss space with a cell-based, autologous approach comparable to Regenera Activa's tissue-derived micrografting.

Broad incumbents

• Restoration Robotics (ARTAS): Restoration Robotics markets the ARTAS robotic system for hair transplantation procedures. It serves the same physician customer base (hair transplant surgeons and dermatologists) but focuses on robotic follicular unit extraction rather than regenerative tissue processing, making it a complementary rather than direct competitor.
• Venus Concept (NeoGraft): Venus Concept sells NeoGraft, an automated follicular unit extraction (FUE) device for hair transplantation, and other aesthetic medicine devices. It addresses the same hair restoration patient population as Regenera Activa through the same physician channel but with a transplantation-focused rather than regenerative approach.

Others

• Eclipse MedCorp: Eclipse MedCorp manufactures PRP (platelet-rich plasma) preparation systems widely used by dermatologists and hair restoration clinics. It is an adjacent technology in the regenerative hair loss category, often used as a cheaper alternative or adjunct to Regenera Activa's AMT procedures in the same physician practices.
• Human Brain Wave: Human Brain Wave is the Italian fabrication and distribution partner for the Rigenera technology, founded in 2012 by the original inventors. It is a technology and channel partner rather than a competitor, but operates in the same regenerative medicine space and represents a critical ecosystem participant for Regenera Activa's product supply.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/RegeneraActiva
• LinkedInlinkedin.com/company/regenera-activa
• Instagraminstagram.com/regeneraactiva_amt

Compliance9 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Regenera Activa