Genomic Medicine Institute
The Genomic Medicine Institute is a translational and clinical human genetics and genomics research department within Cleveland Clinic's Lerner Research Institute, operating SomaScan proteomics, biorepository, and computational oncology cores, conducting disease-focused research across brain, cancer, cardiovascular, and inflammation, and delivering personalized genetic healthcare through the Center for Personalized Genetic Healthcare.
- Company typePrivate
- Founded1921
- HeadquartersCleveland, United States
- Headcount5,001–10,000
- GTM typeB2B
- OfferingServices
What Genomic Medicine Institute does
The Genomic Medicine Institute is a translational and clinical human genetics and genomics research department within Cleveland Clinic's Lerner Research Institute, headquartered at 9500 Euclid Avenue, Cleveland, Ohio. It conducts bench-to-bedside investigation across brain, cancer, heart and blood vessels, inflammation, and systems biology and bioinformatics, organized through individual labs such as the Feixiong Cheng Lab (network medicine and drug target identification), the Ignacio Mata Lab (Parkinson's disease genetics in Latino populations), and the Mihriban Karaayvaz Lab (breast cancer therapeutic vulnerabilities). It operates a portfolio of fee-for-service cores accessible globally via the iLab (Agilent) request portal, including SomaScan 7k and 11k Proteomic Platforms (the only such facility in Northeast Ohio), the Genomics core, the Genomic Medicine Institute Biorepository, and the CITI Computational Oncology Platform and Discovery Lab (HLA/TCR sequencing, bulk and single-cell RNA-seq, neoantigen screening). It also delivers clinical care through the Center for Personalized Genetic Healthcare.
Its core technology stack is a layered platform-plus-modules architecture: a translational genomics foundation anchored in proprietary analytical methods (GenT, a gene-level AI method for drug development; a network-medicine and systems-biology framework), supported by a clinical-genomic data infrastructure (MaGiC data warehouse, CCF cBioPortal, IOExplorer immunogenomics platform) that integrates internal sources (PLMI, Taussig Cancer Institute, Enterprise Analytics) with external panel providers (Tempus, Caris). Recent moves include the launch of GenT, expansion of IBM Quantum-based drug design work, and integration into the $500M Cleveland Innovation District (Global Center for Pathogen and Human Health Research).
The institute's revenue model is institutional rather than commercial. Research funding flows through Cleveland Clinic Research's $479M annual envelope (2025) across 236 labs and 2,400+ caregivers, sourced from federal agencies (NIH, DoD, NSF, AHRQ), foundations (AHA, PCORI), and state co-investment ($200M from JobsOhio plus $300M from Cleveland Clinic). Secondary revenue streams include usage-based core service fees through iLab, industry-sponsored bioinformatics and immuno-sequencing work, and technology commercialization via Cleveland Clinic Innovations (licensing and royalties). Customer segments span Cleveland Clinic investigators, external academic and clinical researchers, industry/pharma collaborators, patients of the Center for Personalized Genetic Healthcare, research participants/donors (including under-represented populations), and trainees from high school through postdoctoral levels.
Genomic Medicine Institute firmographics
Firmographics- Name
- Genomic Medicine Institute
- Legal name
- Cleveland Clinic (Genomic Medicine Institute operates as a department within Cleveland Clinic)
- Website
- https://lerner.ccf.org
- Company type
- Private
- Founded year
- 1921
- Operating status
- Operating
- Headcount range
- 5,001–10,000 employees
- Short description
- The Genomic Medicine Institute is a translational and clinical human genetics and genomics research department within Cleveland Clinic's Lerner Research Institute, operating SomaScan proteomics, biorepository, and computational oncology cores, conducting disease-focused research across brain, cancer, cardiovascular, and inflammation, and delivering personalized genetic healthcare through the Center for Personalized Genetic Healthcare.
- Ownership category
- akta.pro rank
Genomic Medicine Institute industry classification
Industry- Product category
- Genomics Research Services
- NAICS
- Medical Laboratories (621511)
- SIC
- Services-Medical Laboratories (8071)
- akta.pro primary industry
- Molecular Diagnostics & Genomics Laboratories (HLAFAMAE)
- akta.pro secondary industries
- Genomics & Molecular Diagnostics (Trial Support) (HLAGAEAD), Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD), Transcriptomics & Gene Expression Profiling Services (HLAGANAE)
Keywords
Where Genomic Medicine Institute is headquartered
LocationHeadquarters
- HQ city
- Cleveland
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
Genomic Medicine Institute business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Infrastructure, Supply Chain
Revenue model
- Research grants and extramural funding: $479M annual research funding (2025) flowing through 236 labs at Cleveland Clinic Research, sourced from federal agencies (NIH, DoD, NSF, AHRQ), foundations (AHA, PCORI), and internal funding programs. Since 2018 the Office of Research Development has supported 425+ grant submissions and 110+ grant awards totaling $490M+.
- State economic development co-investment: $200M from Ohio/JobsOhio plus $300M co-invested by Cleveland Clinic funds the Global Center for Pathogen & Human Health Research under the Cleveland Innovation District initiative, supporting Genomics-relevant research infrastructure.
- Core service fees (fee-for-service): Cores and platforms charge for services through iLab (Agilent), including 3D Printing, Bioimage Analysis, BioRobotics, SomaScan & Biomarker, Genomics, Computational Oncology Platform, and the Genomic Medicine Institute Biorepository.
- Technology commercialization and licensing: Cleveland Clinic Innovations, the commercialization arm, helps departments patent and commercialize therapies; Biomedical Engineering has a proven track record of patenting and product commercialization in cardiology, urology and neurology.
- Industry-sponsored core services: CITI Computational Oncology Platform and Discovery Lab provide bioinformatics and immuno-sequencing services to academic, clinical and industry partners, including neoantigen screening, HLA/TCR sequencing, and bulk/single-cell RNA-seq analysis.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| — | — | iLab-based fee-for-service quotes for cores (3D Printing, Genomics, SomaScan, Biorepository, Computational Oncology Platform) |
Go-to-market motion1 record
Distribution channels5 records
Marketing channels6 records
Genomic Medicine Institute product offering
Product offeringCore offering
The Genomic Medicine Institute is a translational and clinical human genetics and genomics research department within Cleveland Clinic's Lerner Research Institute that delivers research services, advanced proteomics and genomics core capabilities, biorepository access, and personalized genetic healthcare. It operates fee-for-service cores including SomaScan & Biomarker, the Genomic Medicine Institute Biorepository, Genomics, and the CITI Computational Oncology Platform, and partners with industry and academic collaborators on drug target identification and biomarker discovery.
Product overview
The Genomic Medicine Institute is a single unified department within Cleveland Clinic Research whose offering is a platform-plus-modules architecture: a translational and clinical human genetics and genomics research core anchored by the SomaScan & Biomarker Core Services (powered by SomaLogic's SomaScan 7k and 11k Proteomic Platforms) and the Genomic Medicine Institute Biorepository, combined with the Center for Personalized Genetic Healthcare clinical program and a portfolio of thematic research programs (Brain, Cancer, Heart & Blood Vessels, Inflammation, and Systems Biology & Bioinformatics) delivered through individual labs such as the Feixiong Cheng Lab, Ignacio Mata Lab, and Mihriban Karaayvaz Lab.
Differentiator
Problem solved
Functional benefit
Brands
- Center for Personalized Genetic Healthcare: Clinical care arm affiliated with the Genomic Medicine Institute that centers treatment around each patient's unique genetic profile and its impact on them and their family.
- Genomic Medicine Institute Biorepository
Products and services
- SomaScan & Biomarker Core Services
Quantifiable outcome
- Only facility in Northeast offering SomaScan 7k and 11k Proteomic Platforms
- +3 more outcomes
Companies that use Genomic Medicine Institute
Customer profileNamed customers8 records
Segments6 records
Ideal customer profiles2 records
Genomic Medicine Institute technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability4 records
Feature8 records
Genomic Medicine Institute partnerships and signals
Strategic signalPartnerships
15 partnerships are on record, tiered core, flagship and moderate.
- SomaLogiccoreProvider of the advanced SomaScan 7k and 11k Proteomic Platforms operated by the Genomic Medicine Institute. The Institute is the only facility in Northeast offering these targeted proteomics assays for biomarker discovery. Service access is via the SomaScan & Biomarker Core (lerner.ccf.org/cores/somascan-biomarker/).
- Center for Personalized Genetic Healthcare (Cleveland Clinic)flagshipCleveland Clinic's clinical counterpart that delivers treatment centered around each patient's unique genetic profile. The Genomic Medicine Institute's translational research directly informs the Center's clinical genetic services and patient care.
- Kent State UniversitymoderateCo-developed a quantum-computing-based drug design method with Cleveland Clinic researchers that outperforms classical computing methods for drug design, leveraging Kent State's computational students and faculty.
- Cleveland Clinic Genome CenterflagshipConnects Cleveland Clinic experts from multiple fields to develop advanced genomic technologies and computational tools. Projects span global collaborations to study interconnected ways genomes determine human health and disease.
- Memorial Sloan Kettering Cancer CentercoreCo-developed cBioPortal, the open-source interactive cancer genomics web app used at Cleveland Clinic (CCF cBioPortal) and other major cancer centers. The platform supports genomics reporting for ordering clinicians and scalable genomics research.
- Case Western Reserve UniversityflagshipLong-standing academic partner in the Clinical & Translational Science Collaborative of Cleveland (CTSC), the Molecular Medicine PhD Program, and the Case Comprehensive Cancer Center (NIH P30 CA43703 shared resources).
- MetroHealthmoderatePartner in the Clinical & Translational Science Collaborative of Cleveland (CTSC), a catalyst for high-quality clinical and translational research locally and nationally.
- University HospitalsmoderatePartner in the Clinical & Translational Science Collaborative of Cleveland (CTSC), supporting joint clinical and translational research.
- Louis Stokes Veterans Administration Medical CentermoderatePartner in the Clinical & Translational Science Collaborative of Cleveland (CTSC), enabling joint clinical and translational research with the VA system.
- Case Comprehensive Cancer CentercoreNIH-funded cancer center partnership (P30 CA43703) whose Shared Laboratory Resources complement Cleveland Clinic Research's Genomics, Imaging, and Proteomics & Metabolomics Cores, offering technologies and services beyond those available at Cleveland Clinic.
- IBMcoreCollaborated with Cleveland Clinic to develop an AI-powered solution that improves reproducibility in cell culturing, and provides access to the IBM Quantum System One for Cleveland Clinic's quantum computing research relevant to genomics and drug design.
- St. Jude Children's Research HospitalmoderateResearch collaboration that identified SMARCAL1 as a risk gene for childhood osteosarcoma, by looking beyond known cancer genes.
- Taussig Cancer Institute (Cleveland Clinic)coreInternal Cleveland Clinic partner that collaborates with the CITI Computational Oncology Platform to operate the Precision Oncology Program and integrate clinical-genomic data into MaGiC.
- Pathology & Laboratory Medicine Institute (PLMI)coreInternal Cleveland Clinic partner collaborating with CITI on the Precision Oncology Program, integrating molecular sequencing results and clinical data into MaGiC.
- Cleveland Clinic Quantum Innovation Catalyzer ProgrammoderateProgram empowering start-ups to conduct breakthrough quantum computing research with access to the IBM Quantum System One, supporting genomics-related drug design and computational biology applications.
Scale indicators10 records
Recent moves6 records
Expansion highlights6 records
Genomic Medicine Institute competitors and assessment
Company assessmentDirect peers
- HudsonAlpha Institute for Biotechnology: A nonprofit genomics and clinical sequencing institute offering fee-for-service genomic analysis and translational research. Comparable in providing clinical genomic services, conducting translational research, and operating as a hybrid academic-commercial genomics center.
- Mayo Clinic Center for Individualized Medicine: The genomics and precision medicine arm of a peer top-tier U.S. nonprofit hospital system. Directly comparable as an academic medical center's translational genomics and individualized medicine program with clinical care integration.
- St. Jude Children's Research Hospital: A pediatric-focused research hospital with substantial translational genomics, including recent GMI collaborations (SMARCAL1 osteosarcoma gene). Comparable in nonprofit research-hospital genomics, biobanking, and disease-focused genetic discovery programs.
- Baylor College of Medicine Human Genome Sequencing Center: A major academic genomic medicine and sequencing center embedded in a large U.S. medical school. Comparable to GMI in translational genomics research, sequencing/proteomics cores, and NIH-funded program portfolio.
- New York Genome Center: A nonprofit translational genomics collaborative serving academic and industry partners in the New York region. Directly comparable to GMI in its academic-industry hybrid model, sequencing cores, and translational research mandate.
- Jackson Laboratory for Genomic Medicine: An independent nonprofit genomics research institute focused on translational and clinical genomics, mouse models, and precision medicine. Closely comparable to GMI in mission, model (nonprofit genomics institute), and service offerings.
- Vanderbilt Genetics Institute: A genetics and genomics research institute within Vanderbilt University Medical Center with biobanking, translational programs, and AI-driven genomics. Comparable to GMI in academic medical center genomic medicine scope and infrastructure.
- Icahn Institute for Genomics and Multiscale Biology (Mount Sinai): A genomics and systems biology institute within a major U.S. academic medical center. Comparable in integrating network medicine, computational biology, and clinical-genomic data within a hospital-based research enterprise.
Broad incumbents
- NIH National Human Genome Research Institute (NHGRI): The federal government's lead agency for genomics research. Comparable in translational genomics mandate but operates as a much larger federally funded national-scale institute rather than a hospital-embedded department.
- Broad Institute of MIT and Harvard: A leading genomics and biomedical research institute with extensive translational programs, large-scale sequencing, and a genome center. Comparable in translational genomics focus but operates at a significantly larger scale and with broader disease-area coverage.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks4 records
Key highlights7 records
Customer concentration
Genomic Medicine Institute social profiles
Digital presenceGenomic Medicine Institute financial estimates
Financial estimateRevenue estimate
Valuation estimate
Genomic Medicine Institute leadership team
Management profileNumber of profiles
Genomic Medicine Institute subsidiaries and ownership
Company hierarchySubsidiaries3 records
Genomic Medicine Institute funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Genomic Medicine Institute M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Genomic Medicine Institute
What does Genomic Medicine Institute do?
The Genomic Medicine Institute is a translational and clinical human genetics and genomics research department within Cleveland Clinic's Lerner Research Institute that delivers research services, advanced proteomics and genomics core capabilities, biorepository access, and personalized genetic healthcare. It operates fee-for-service cores including SomaScan & Biomarker, the Genomic Medicine Institute Biorepository, Genomics, and the CITI Computational Oncology Platform, and partners with industry and academic collaborators on drug target identification and biomarker discovery.
Is Genomic Medicine Institute a public or private company?
Genomic Medicine Institute is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was Genomic Medicine Institute founded?
Genomic Medicine Institute was founded in 1921. It employs 5,001 to 10,000 people.
Where is Genomic Medicine Institute based?
Genomic Medicine Institute is headquartered in Cleveland, United States, in the North America region.
How does Genomic Medicine Institute make money?
Five revenue lines are on record. Research grants and extramural funding is the primary driver. The others are state economic development co-investment, core service fees (fee-for-service), technology commercialization and licensing and industry-sponsored core services.
Who are Genomic Medicine Institute's main competitors?
Direct peers on record are HudsonAlpha Institute for Biotechnology, Mayo Clinic Center for Individualized Medicine, St. Jude Children's Research Hospital, Baylor College of Medicine Human Genome Sequencing Center, New York Genome Center, Jackson Laboratory for Genomic Medicine, Vanderbilt Genetics Institute and Icahn Institute for Genomics and Multiscale Biology (Mount Sinai). Broad incumbents are NIH National Human Genome Research Institute (NHGRI) and Broad Institute of MIT and Harvard.
Does Genomic Medicine Institute have an API?
No public API is recorded for Genomic Medicine Institute.
What industry is Genomic Medicine Institute in?
Genomic Medicine Institute's product category is Genomics Research Services. Its primary akta.pro industry code is HLAFAMAE, Molecular Diagnostics & Genomics Laboratories, with a secondary code of HLAGAEAD, Genomics & Molecular Diagnostics (Trial Support). Its NAICS code is 621511 and its SIC code is 8071.