Zist Takhmir Pharmaceutical Co.

What Zist Takhmir Pharmaceutical Co. does

Zist Takhmir Pharmaceutical Co. is an Iranian knowledge-based pharmaceutical company founded in 2002 at the Faculty of Pharmacy of Tehran University of Medical Sciences. It pioneered domestic probiotic production in Iran, a category that was previously 100% import-dependent, and has since built a portfolio spanning probiotic and synbiotic supplements (Pedilact, Familact, Gerilact, Wellgut, Kidilact, Lactovag, Loctofem, Loctocare, Dallyeast, Entrolact), prescription medicines (Zymucil/acetylcysteine, Ibrutinib/Brucka for hematologic malignancies), vitamins and minerals (Bio Bion liposomal iron, Dr Gamphi, FertiMale, FertiFemale), and natural products (Colprebs peppermint oil, Rojevit royal jelly).

The company's core technology is indigenous microbial fermentation: it isolates and registers native probiotic strains from the normal flora of Iranian individuals and produces probiotics in capsules, sachets, oral drops, and vaginal tablets using a three-stage process of bacterial fermentation, fortification, and drying. It holds registered Patent No. 63124 for an efficient spray drying method tailored to Iran's facilities. Manufacturing is conducted at a main site in Pardis Technology Park (with annual capacities of 2 billion capsules, 1.56 billion tablets, 500 million powder units, 300 million solution units, and 100 million drop units) under GMP-compliant Class A/D infrastructure with HPLC, GC, ICP-OES, PCR, lyophilization, and a -85°C cell bank of 700 lines. A central office in Tehran's Pol Sadiq district and an R&D site on Enghelab Street support operations.

Zist Takhmir operates a business-to-consumer pharmaceutical model, distributing products through Iran's retail pharmacy network, its own pharmacy outlet in Tehran, and direct healthcare institution supply, supported by digital channels (website, Instagram, WhatsApp, Telegram, LinkedIn, Aparat) and participation in pharmaceutical exhibitions and congresses. Revenue is generated across four streams—probiotic/synbiotic products, prescription medications, vitamins and minerals, and natural health products—with pricing set by retail channels rather than publicly disclosed. The company employs 400+ families directly and 100 indirectly, with 40+ MSc/PhD R&D personnel, and holds ISO 9001, ISO 27001, HACCP certifications plus all required Iran's FDA (SDA) product licenses. It operates four wholly-owned subsidiaries: Zist Darman Danesh (chemical/biological pharma including MS, oncology, and rare disease treatments), Zist Darman Mahan (animal probiotics under the BioDEP brand), Bonian Salamat Kasra (traditional/natural medicine), and Exzon (bio-based accelerator for probiotics and functional foods).

Name

Zist Takhmir Pharmaceutical Co.

Legal name

Zist Takhmir Pharmaceutical Co.

Website

https://zisttakhmir.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

501–1,000 employees

Short description

Zist Takhmir Pharmaceutical Co. is an Iranian knowledge-based pharmaceutical manufacturer founded in 2002, pioneering domestic probiotic production through indigenous fermentation technology. It serves Iranian consumers and patients across probiotics, prescription medicines, vitamins, and natural health products via retail pharmacies, supported by an in-house accelerator and four subsidiaries.

Ownership category

akta.pro rank

Product category

Pharmaceutical Products

NAICS

Pharmaceutical Preparation Manufacturing (325412), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Pharmaceutical Preparations (2834), Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Probiotics & Digestive Health Supplements (CRADAGAF)

Keywords

• Probiotic supplements
• Pharmaceutical manufacturing
• Synbiotic formulations
• Vitamin mineral supplements
• Natural health products

Headquarters

HQ city

Tehran

HQ country

Iran

HQ region

Middle East

Offices4 records

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Probiotic Products: Sale of probiotic and synbiotic products including Pedilact, Familact, Gerilact, Wellgut, Kidilact, Lactovag, and others across categories for infants, children, adults, elderly, and women. Products sold in various forms: capsules, sachets, oral drops, and vaginal tablets.
2. Medications: Sale of pharmaceutical products including Zymucil (acetyl cysteine), Ibrutinib (Broka), Rojevit (royal jelly + vitamin C), and others requiring prescription.
3. Vitamins and Minerals: Sale of vitamin and mineral supplements including Bio Bion (liposomal iron), Biobion syrup, Dr Gamphi multivitamin, FertiMale, FertiFemale, and others.
4. Natural Health Products: Sale of natural health products including Colprebs (peppermint oil enteric-coated capsules) and Rojevit products.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Zist Takhmir manufactures and sells probiotic, synbiotic, pharmaceutical, vitamin, mineral, and natural health products for human consumption in various dosage forms including capsules, sachets, oral drops, vaginal tablets, lozenges, vials, syrups, and tablets. As the pioneer of domestic probiotic production in Iran, the company produces products using indigenous bacterial strains isolated from the normal flora of Iranian individuals, addressing gastrointestinal, women's health, infant/child health, and elderly wellness needs. Products are distributed through retail pharmacy networks across Iran, with current capacity of 300 million units/year of liquid products and 2 billion capsules/year.

Product overview

Zist Takhmir Pharmaceutical Co. is an Iranian knowledge-based pharmaceutical company established in 2002 at the Faculty of Pharmacy of Tehran University of Medical Sciences, pioneering domestic probiotic production in Iran. The company's product portfolio comprises four main categories: (1) Probiotic/Synbiotic Supplements - including Wellgut family (Eczema, Fiber, IBS, D3), Familact/Gerilact families (Two Plus variants with enteric coating), and pediatric products (Pedilact, Kidilact, Kidigurd, Babecare, Babeyeast); (2) Women's Health Products - Lactovag vaginal probiotics and Loctofem oral synbiotic; (3) Medicines & Natural Products - Zymucil (acetylcysteine), Ibrutinib (anticancer), Rojevit (royal jelly), Colprbs (peppermint oil); (4) Vitamins & Minerals - Bio Bion/Biobion (liposomal iron with B vitamins), FertiMale/FertiFemale (fertility supplements), Dr Gamphi (multivitamin pastilles). The company also operates a probiotic accelerator (Exzon) and subsidiary companies including Zist Darman, Boniad Salamat Kasri, and Zist Darman Mahann.

Differentiator

Problem solved

Functional benefit

Products and services

• Pedilact 3 Plus (پدی لاکت 3 پلاس) A synbiotic pediatric formulation containing simethicone and probiotic strains (Lactobacillus rhamnosus, Lactobacillus reuteri, Bifidobacterium infantis) along with dill oil and fennel for infants and children from birth to 2 years, addressing colic, bloating, diarrhea, and lactose intolerance.
• Vitalact (ویتالاکت) A dual-layer tablet combining probiotics, vitamins, and minerals (A, D3, E, K, C, B1, B2, B3, B6, B12, folic acid, iron, magnesium, zinc) with three probiotic strains for adult consumers seeking comprehensive nutritional support.
• Wellgut Eczema (ول‌گات اگزما) A probiotic product for children over 6 months containing high doses of Lactobacillus casei, Bifidobacterium longum, Bifidobacterium lactis with inulin, designed to reduce eczema symptoms including redness, swelling, and itching.
• Wellgut Fiber (ول‌گات فیبر) A synbiotic product for children over 1 year as oral sachet containing Lactobacillus rhamnosus GG with inulin as prebiotic, for regulating bowel movements and preventing constipation.
• Wellgut IBS (ول‌گات آی بی اس) A probiotic product for reducing IBS symptoms including bloating, abdominal pain, diarrhea, and constipation for children over 12 years and adults, containing Bifidobacterium longum.
• Familact Capsule (کپسول فمی لاکت) A synbiotic formula containing high doses of beneficial bacterial strains with FOS as prebiotic, suitable for all family members, addressing gastroenteritis, diarrhea, IBD, IBS, cardiovascular diseases, fatty liver, diabetes type 2, and lactose intolerance.
• Gerilact (ژری لاکت) A synbiotic formula specifically designed for elderly and all family members containing beneficial bacterial strains with FOS as prebiotic, addressing chronic constipation, bloating, cardiovascular diseases, osteoporosis, diabetes type 2, and fatty liver.
• Lactogum (لاکتوگام) A probiotic lozenge for individuals over 5 years with mint flavor containing beneficial bacterial strains for maintaining oral and dental health, reducing pharyngitis, respiratory infections, and halitosis.
• Familact Two Plus (فمی لاکت توپلاس) An advanced synbiotic formula with higher probiotic population and enteric-coated capsules for direct delivery to intestines, suitable for all family members addressing gastrointestinal issues.
• Gerilact Two Plus (ژری لاکت توپلاس) An enhanced synbiotic formula with higher probiotic population for elderly, addressing metabolic diseases, osteoporosis prevention, calcium absorption, and digestive issues.
• Loctocare (لاکتوکر) A synbiotic formula for extra needs containing 12 bacterial strains with FOS as prebiotic for immune system strengthening, prevention of hospital-acquired infections, respiratory infections, and post-surgery infections.
• Dallyeast (دیلیست) A probiotic formula from Saccharomyces boulardii yeast strain for various gastroenteritis types, Clostridioides difficile infection, H. pylori treatment, parasitic infections, IBD, IBS, MS symptoms, and metabolic syndrome.
• Entrolact (اینترولاکت) A probiotic product for infants, children, and adults as oral vials containing Bacillus clausii spores resistant to stomach acid for improving intestinal microbiome and producing B vitamins.
• Kidigurd (کیدی گارد) An oral synbiotic formula for children over 6 months as strawberry-flavored sachets containing specific oral microbiome bacterial strain with sorbitol prebiotic for throat, tonsil, and ear inflammation relief.
• Kidilact (کیدی لاکت) A synbiotic formula for children 2-10 years as unflavored oral sachets containing beneficial bacterial strains with FOS for addressing constipation, allergies, diarrhea, and immune support.
• Kidilact Zinc (کیدی لاکت زینک) A synbiotic formula for children 2-10 years containing beneficial bacterial strains with FOS and 5mg zinc gluconate for diarrhea, allergies, and bone, skin, hair, and nail health.
• Pedilact (پدی لاکت) A synbiotic formula for infants and children from birth to 2 years as orange-flavored drops containing beneficial bacterial strains with FOS for addressing colic, infant jaundice, reflux, and lactose intolerance.
• Babecare (بی‌بی‌کر) A synbiotic formula for infants from birth to 2 years as unflavored, unscented drops containing beneficial bacterial strains with FOS for constipation, allergies, NEC prevention in premature infants, reflux, and lactose intolerance.
• Babeyeast (بیبی یست) A synbiotic formula for children over 6 months as unflavored sachets containing Saccharomyces boulardii with sorbitol for acute diarrhea, antibiotic-associated diarrhea, parasitic infections, and respiratory infection prevention.
• Wellgut-D3 (ول گات + د3) A probiotic product for infants and children under 2 years as oral drops containing Lactobacillus rhamnosus GG and Bifidobacterium lactis with Vitamin D3 for gastrointestinal health, bone health, and calcium/phosphorus absorption.
• Lactovag Tablet (لاکتوواژ قرص) A vaginal synbiotic formula for women containing Lactobacillus strains with maltodextrin as prebiotic for preventing and treating bacterial, fungal, and viral infections, HPV, UTI recurrence, menopause symptoms, and vaginal dryness.
• Loctofem (لاکتوفم) An oral synbiotic for girls and women containing beneficial bacterial strains with FOS for reducing menopausal symptoms, endometriosis pain, gestational diabetes prevention, and pregnancy constipation.
• Colprbs (کلپریبس) A natural formula from peppermint oil extract as enteric-coated capsules for adults over 8 years for reducing IBS symptoms, intestinal spasms, indigestion, bloating, and intestinal motility regulation.
• Zymucil 200 (زیموسیل 200) Acetylcysteine as water-soluble sachets with orange flavor in 100mg and 200mg doses for infants over 1 month and adults for mucus expectoration and respiratory diseases.
• Rojevit Lozenge (روژویت مکیدنی) A natural formula from royal jelly gel and vitamin C as peach-flavored lozenges for all family members for wrinkle prevention, fertility enhancement, and immune system strengthening.
• Rojevit Vial (روژویت ویال) A natural formula from royal jelly as orange-flavored oral liquid vials for all family members for overall health and wellness.
• Bio Bion (بایو بیون) The first liposomal iron oral liquid with zinc and B vitamins in five-fruit flavor for all individuals, containing liposomal iron 18mg, zinc citrate 10mg, folic acid, biotin, B1, B2, B3, B6, B12 for red blood cell production and anemia relief.
• Biobion (بایوبیون) A liposomal iron syrup with zinc and B vitamins in cherry flavor for daily use by individuals over 12 years for red blood cell production, anemia relief, and energy enhancement.
• Ibrutinib (Brucka) (ایبروتینیب) Brucka brand anticancer drug in 140mg and 420mg film-coated tablets containing Ibrutinib as irreversible BTK inhibitor for Mantle Cell Lymphoma (MCL), Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Leukemia (SLL), Lymphoplasmacytic Lymphoma (Waldenstrom's Macroglobulinemia: WM), Marginal Zone Lymphoma (MZL), and chronic graft-versus-host disease (cGVHD) treatment.
• Dr Gamphi (دکتر گامفی) Multivitamin chewing pastilles for children over 4 years and adults with natural colors, gelatin base containing vitamins and minerals for health improvement, metabolism, immune system, and bone/cartilage/teeth health.
• FertiMale (فرتی مِیل) A male fertility health enhancement supplement as film-coated tablets containing vitamins B6, B12, L-arginine, L-carnitine, CoQ10, vitamin E, zinc, selenium, and vitamin D3 for improving sperm quality and male reproductive health.
• FertiFemale (فرتی فیمیل) A female fertility enhancement supplement as film-coated tablets containing inositol 512.5mg, folic acid, CoQ10, B12, melatonin, vitamin E, and selenium for improving ovarian function, ovulation, and PCOS management.
• Wellgut One (ول گات وان) A probiotic product for infants and children under 2 years as oral drops containing Lactobacillus reuteri for maintaining gum and tooth health and balancing normal oral microbiome.

Quantifiable outcome

• Liquid production capacity: 300 million units/year (solutions), 100 million units/year (drops)
• +3 more outcomes

Named customers4 records

Segments5 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Four partnerships are on record, tiered core.

• Bonian Salamat Kasra (بنیان سلامت کسری)coreStrategic or Co-development PartnerA knowledge-based company that commenced activities in 1393 (2014) at the growth center of Traditional Medicine and Natural Products of Tehran University of Medical Sciences. It has successfully registered several natural and chemical compounds with Iran's FDA. Bonian Salamat Kasra operates clinical laboratories and research facilities to produce high-quality, effective products. It is a subsidiary of Zist Takhmir.
• Zist Darman Mahan (زیست درمان ماهان)coreStrategic or Co-development PartnerEstablished in 1394 (2015) with participation from Zist Takhmir to develop probiotic supplements for livestock, poultry, and aquatic animals. The company isolates and registers probiotic microorganisms from native sources and is a member of Pardis Science and Technology Park. Products are marketed under the BioDEP brand, serving ruminants, poultry, fish, shrimp, horses, ornamental fish, birds, and pets.
• Exzon (اکسزون)coreStrategic or Co-development PartnerA bio-based accelerator for probiotics and functional foods, operating under Zist Takhmir as Iran's first probiotic product manufacturing company. Exzon serves as an innovation accelerator supporting startups and companies in the probiotic and functional food ecosystem.
• Zist Daru Danesh (زیست دارو دانش)coreStrategic or Co-development PartnerA private knowledge-based pharmaceutical company established in 1384 (2005) operating in chemical and biological pharmaceutical product manufacturing and marketing. Located at Pardis Technology Park with 4 production lines including recombinant protein (bacterial), monoclonal antibody production, vial filling/lyophilization, and high-risk oral products. Produces treatments for MS, various cancers, and rare diseases. Also produces contract pharmaceutical products including high-risk drugs and lyophilized vials.

Scale indicators6 records

Recent moves9 records

Expansion highlights6 records

Direct peers

• BioGaia: Swedish probiotic product manufacturer with a portfolio of Lactobacillus reuteri-based strains marketed globally. Directly comparable to Zist Takhmir's probiotic supplement business model, with a similar focus on clinically documented, strain-specific probiotic products.
• Winclove Probiotics: Dutch probiotic manufacturer developing multi-strain formulations for specific indications (IBS, women's health, immune support). Closely comparable to Zist Takhmir's indication-specific probiotic design approach and B2B supply model.
• Probi AB: Swedish probiotic supplier developing and marketing clinically documented probiotic strains through B2B partnerships and branded products. Directly comparable as a research-driven probiotic company with proprietary strains and multiple delivery formats.

Broad incumbents

• ADM (Protexin): ADM's Protexin/H&B group manufactures probiotic-branded consumer products and ingredient solutions. Comparable to Zist Takhmir's branded probiotic portfolio and its multi-form production capacity (capsules, sachets, drops).
• Garden of Life (Nestlé Health Science): Nestlé Health Science-owned supplement brand offering probiotics, prenatal vitamins, and digestive health SKUs. Comparable to Zist Takhmir's consumer-facing multi-category supplement portfolio including fertility and pediatric lines.
• Lallemand Health Solutions: Probiotic and yeast-based supplement manufacturer supplying branded and bulk probiotic formulations globally. Comparable to Zist Takhmir's probiotic and synbiotic supplement manufacturing operations across multiple dosage forms.
• Ganeden (Kerry Group): Probiotic ingredient maker (Bacillus coagulans GBI-30) now part of Kerry Group, supplying ingredients across food, beverage, and supplement categories. Comparable to Zist Takhmir's proprietary strain approach and ingredient-level capabilities.
• Chr. Hansen (Novonesis): Global leader in microbial and probiotic cultures (now part of Novonesis) supplying cultures and probiotic strains to food, supplement, and pharma companies. Comparable as a probiotic strain and ingredient manufacturer with broad formulation capabilities.

Emerging players

• Yakult Honsha: Japanese probiotic beverage and supplement company built around Lactobacillus casei Shirota. Comparable as a probiotic consumer brand with strong consumer recognition and clinical emphasis, though primarily beverage-led.
• Culturelle (i-Health): Lactobacillus rhamnosus GG-based probiotic supplement brand marketed in the US and globally. Comparable as a single-strain probiotic brand targeting digestive and gut health — a core use case for Zist Takhmir's Familact and Gerilact lines.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeaparat.com/Zisttakhmir.com
• LinkedInlinkedin.com/company/probiotic
• Instagraminstagram.com/zisttakhmir
• Facebookfacebook.com/profile.php

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zist Takhmir Pharmaceutical Co.