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Mitobridge

Full company profile

uuid003vwki

Namestring
Mitobridge
Legal namestring
Slabmedia, LLC
Websiteurl
mitobridge.com
Company typeenum
Private
Founded yearint
2011
Descriptiontext

Mitobridge is a privately held biotechnology company founded in 2011 in Cambridge, Massachusetts. According to its firmographic profile, the company discovers and develops small molecule therapeutics aimed at improving mitochondrial functions, positioning it within the mitochondrial disease and bioenergetics therapeutic space. It operates with a lean organization of 11–50 employees and maintains a web presence at mitobridge.com.

The company has raised capital from a syndicate of biotech-focused investors. Its initial founding event in 2011 was backed by MPM Capital, and a subsequent disclosed equity round on October 4, 2013, totaled approximately $5.22 million with participation from Longwood Fund and a strategic pharmaceutical investor, Astellas Pharma. Capital has been directed toward building a small molecule drug discovery platform with explicit medicinal chemistry capability, evidenced by the hiring of Takeru Furuya as Associate Director of Medicinal Chemistry and founder-led oversight from Kazumi Shiosaki, who serves as President & CEO.

As a development-stage biotech with no disclosed commercial products, partnerships, or licensing revenue, Mitobridge's progress depends on continued financing, scientific milestones, or strategic transactions. The early-stage strategic investment by Astellas Pharma is notable as a signal of pharma-level validation of the mitochondrial therapeutic thesis and as a potential channel for future partnership, licensing, or acquisition activity. The data set does not disclose post-2013 financing, pipeline progression, or headcount trends, limiting visibility into the company's current operating trajectory.

Short descriptiontext

Mitobridge is a privately held biotechnology company founded in 2011 in Cambridge, Massachusetts, developing small molecule therapeutics that improve mitochondrial functions. It targets mitochondrial disease through medicinal chemistry-driven drug discovery, backed by MPM Capital, Longwood Fund, and Astellas Pharma.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
11–50
akta.pro rankint
HeadquartersCambridge, United States
HQ citystring
Cambridge
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
small molecule therapeutics, mitochondrial drug discovery, rare disease therapeutics, preclinical drug development, biopharmaceutical research
Industry2 codes
1Microbiome Modulating Small Molecules & Antibiotic Alternatives
CodeHLAAAFAGPrimaryYes
2Microbiome Analytics, Sequencing & Bioinformatics Platforms
CodeHLAAAFAIPrimaryNo
NAICS code1 code
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
SIC code3 codes
  • In Vitro & In Vivo Diagnostic Substances2835
  • Medicinal Chemicals & Botanical Products2833
  • Services-Commercial Physical & Biological Research8731
Product category
Mitochondrial Therapeutics
GTM motion1 record

Each record includes

Type, Description, Source

Revenue model1 record
1Web Design and Development Services
TypeProfessional Services
Description

Custom website design and development services using hand-coded solutions without templates. Includes ongoing support, updates, and custom functionality creation. Revenue generated through project-based engagements and service contracts.

slabmedia.com
Marketing channels3 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels2 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components3 values
Personnel, Technology or R&D, Operations
Pricing details1 tier
1Custom Service Levels & Pricing
ModelOtherBilling cadenceMonthly
Notes

Pricing information is available through 'Slab Service Levels & Pricing' page but not detailed in the source. Contact-based pricing model.

slabmedia.com
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Mitobridge is discovering and developing small molecule therapeutics that improve mitochondrial functions. The company focuses on mitochondrial biology to identify orally bioavailable drug candidates targeting diseases linked to mitochondrial dysfunction, including rare genetic mitochondrial disorders and broader metabolic indications. It operates as a preclinical-stage biopharmaceutical research organization based in Cambridge, Massachusetts.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 value
  • Tremendous positive client feedback for law firm website - serves industry perfectly
Recent move4 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight3 records

Each record includes

Type, Description

Peers10 records
TypeOthers
Description

Healthcare-dedicated venture capital firm that seeded and led Mitobridge's Series A; comparable as an investor in the mitochondrial/rare-disease biotech ecosystem rather than a product peer.

2Stealth BioTherapeutics
TypeDirect peer
Description

Clinical-stage biotech developing small molecule therapeutics targeting mitochondrial dysfunction across rare diseases and ophthalmology; the most directly comparable mitochondrial small-molecule peer to Mitobridge.

TypeDirect peer
Description

Mitochondrial disease biotech developing both small molecule and gene therapy approaches for disorders of mitochondrial function; comparable indication focus though broader modality.

TypeDirect peer
Description

Clinical-stage company developing mitochondrial cell therapies and small molecule approaches for mitochondrial diseases; comparable in mitochondrial mechanism and rare disease focus.

TypeDirect peer
Description

Clinical-stage biotech developing mitochondria-derived peptides (MDBPs) for metabolic and age-related diseases; comparable in addressing mitochondrial biology for systemic disease.

TypeDirect peer
Description

Discovery/preclinical-stage company developing small molecule inhibitors of mitochondrial permeability transition pore for neurodegenerative diseases; comparable mitochondrial-mechanism focus.

TypeDirect peer
Description

Clinical-stage mitochondrial therapeutics company developing small molecules for inherited mitochondrial diseases; closely comparable in modality and disease focus.

TypeDirect peer
Description

Swedish clinical-stage biotech developing therapies for primary mitochondrial disease, including both small molecule and NAD+ precursor approaches; comparable therapeutic area and stage.

TypeOthers
Description

Boston-area biotech venture firm and Mitobridge Series A co-investor; comparable as a fellow investor in early-stage Cambridge biotechs rather than as a product competitor.

TypeBroad incumbent
Description

Global Japanese pharmaceutical company and existing Mitobridge investor; broader portfolio across multiple therapeutic areas, with strategic interest in mitochondrial and rare disease programs.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat2 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights5 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers11 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment4 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature1 record

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles2 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds2 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors3 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Mitobridge

Mitochondrial Therapeuticsmitobridge.com

Mitobridge is a privately held biotechnology company founded in 2011 in Cambridge, Massachusetts, developing small molecule therapeutics that improve mitochondrial functions. It targets mitochondrial disease through medicinal chemistry-driven drug discovery, backed by MPM Capital, Longwood Fund, and Astellas Pharma.

What Mitobridge does

Mitobridge is a privately held biotechnology company founded in 2011 in Cambridge, Massachusetts. According to its firmographic profile, the company discovers and develops small molecule therapeutics aimed at improving mitochondrial functions, positioning it within the mitochondrial disease and bioenergetics therapeutic space. It operates with a lean organization of 11–50 employees and maintains a web presence at mitobridge.com.

The company has raised capital from a syndicate of biotech-focused investors. Its initial founding event in 2011 was backed by MPM Capital, and a subsequent disclosed equity round on October 4, 2013, totaled approximately $5.22 million with participation from Longwood Fund and a strategic pharmaceutical investor, Astellas Pharma. Capital has been directed toward building a small molecule drug discovery platform with explicit medicinal chemistry capability, evidenced by the hiring of Takeru Furuya as Associate Director of Medicinal Chemistry and founder-led oversight from Kazumi Shiosaki, who serves as President & CEO.

As a development-stage biotech with no disclosed commercial products, partnerships, or licensing revenue, Mitobridge's progress depends on continued financing, scientific milestones, or strategic transactions. The early-stage strategic investment by Astellas Pharma is notable as a signal of pharma-level validation of the mitochondrial therapeutic thesis and as a potential channel for future partnership, licensing, or acquisition activity. The data set does not disclose post-2013 financing, pipeline progression, or headcount trends, limiting visibility into the company's current operating trajectory.

Mitobridge firmographics

Firmographics
Name
Mitobridge
Legal name
Slabmedia, LLC
Website
https://mitobridge.com
Company type
Private
Founded year
2011
Operating status
Operating
Headcount range
11–50 employees
Short description
Mitobridge is a privately held biotechnology company founded in 2011 in Cambridge, Massachusetts, developing small molecule therapeutics that improve mitochondrial functions. It targets mitochondrial disease through medicinal chemistry-driven drug discovery, backed by MPM Capital, Longwood Fund, and Astellas Pharma.
Ownership category
akta.pro rank

Mitobridge industry classification

Industry
Product category
Mitochondrial Therapeutics
NAICS
Research and Development in Biotechnology (except Nanobiotechnology) (541714)
SIC
In Vitro & In Vivo Diagnostic Substances (2835), Medicinal Chemicals & Botanical Products (2833), Services-Commercial Physical & Biological Research (8731)
akta.pro primary industry
Microbiome Modulating Small Molecules & Antibiotic Alternatives (HLAAAFAG)
akta.pro secondary industry
Microbiome Analytics, Sequencing & Bioinformatics Platforms (HLAAAFAI)

Keywords

  • Small molecule therapeutics
  • Mitochondrial drug discovery
  • Rare disease therapeutics
  • Preclinical drug development
  • Biopharmaceutical research

Where Mitobridge is headquartered

Location

Headquarters

HQ city
Cambridge
HQ country
United States
HQ region
North America

Offices1 record

Markets served

Mitobridge business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Personnel, Technology or R&D, Operations

Revenue model

  1. Web Design and Development Services: Custom website design and development services using hand-coded solutions without templates. Includes ongoing support, updates, and custom functionality creation. Revenue generated through project-based engagements and service contracts.

Pricing tiers

ModelBillingPrice
OtherMonthlyCustom Service Levels & Pricing

Go-to-market motion1 record

Distribution channels2 records

Marketing channels3 records

Mitobridge product offering

Product offering

Core offering

Mitobridge is discovering and developing small molecule therapeutics that improve mitochondrial functions. The company focuses on mitochondrial biology to identify orally bioavailable drug candidates targeting diseases linked to mitochondrial dysfunction, including rare genetic mitochondrial disorders and broader metabolic indications. It operates as a preclinical-stage biopharmaceutical research organization based in Cambridge, Massachusetts.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

  • Tremendous positive client feedback for law firm website - serves industry perfectly

Companies that use Mitobridge

Customer profile

Named customers11 records

Segments4 records

Ideal customer profiles1 record

Mitobridge technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature1 record

Mitobridge partnerships and signals

Strategic signal

Recent moves4 records

Expansion highlights3 records

Mitobridge competitors and assessment

Company assessment

Others

  • MPM Capital: Healthcare-dedicated venture capital firm that seeded and led Mitobridge's Series A; comparable as an investor in the mitochondrial/rare-disease biotech ecosystem rather than a product peer.
  • Longwood Fund: Boston-area biotech venture firm and Mitobridge Series A co-investor; comparable as a fellow investor in early-stage Cambridge biotechs rather than as a product competitor.

Direct peers

  • Stealth BioTherapeutics: Clinical-stage biotech developing small molecule therapeutics targeting mitochondrial dysfunction across rare diseases and ophthalmology; the most directly comparable mitochondrial small-molecule peer to Mitobridge.
  • Pretzel Therapeutics: Mitochondrial disease biotech developing both small molecule and gene therapy approaches for disorders of mitochondrial function; comparable indication focus though broader modality.
  • Minovia Therapeutics: Clinical-stage company developing mitochondrial cell therapies and small molecule approaches for mitochondrial diseases; comparable in mitochondrial mechanism and rare disease focus.
  • CohBar: Clinical-stage biotech developing mitochondria-derived peptides (MDBPs) for metabolic and age-related diseases; comparable in addressing mitochondrial biology for systemic disease.
  • NRG Therapeutics: Discovery/preclinical-stage company developing small molecule inhibitors of mitochondrial permeability transition pore for neurodegenerative diseases; comparable mitochondrial-mechanism focus.
  • Khondrion: Clinical-stage mitochondrial therapeutics company developing small molecules for inherited mitochondrial diseases; closely comparable in modality and disease focus.
  • Abliva: Swedish clinical-stage biotech developing therapies for primary mitochondrial disease, including both small molecule and NAD+ precursor approaches; comparable therapeutic area and stage.

Broad incumbents

  • Astellas Pharma: Global Japanese pharmaceutical company and existing Mitobridge investor; broader portfolio across multiple therapeutic areas, with strategic interest in mitochondrial and rare disease programs.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat2 records

Key risks5 records

Key highlights5 records

Customer concentration

Mitobridge social profiles

Digital presence

Mitobridge financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Mitobridge leadership team

Management profile

Number of profiles

Profiles2 records

Mitobridge funding detail

Funding detail

Funding overview

Funding rounds2 records

Investors3 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Mitobridge M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Mitobridge

What does Mitobridge do?

Mitobridge is discovering and developing small molecule therapeutics that improve mitochondrial functions. The company focuses on mitochondrial biology to identify orally bioavailable drug candidates targeting diseases linked to mitochondrial dysfunction, including rare genetic mitochondrial disorders and broader metabolic indications. It operates as a preclinical-stage biopharmaceutical research organization based in Cambridge, Massachusetts.

Is Mitobridge a public or private company?

Mitobridge is a private company. It is classified as venture growth investor backed and is currently operating.

When was Mitobridge founded?

Mitobridge was founded in 2011. It employs 11 to 50 people.

Where is Mitobridge based?

Mitobridge is headquartered in Cambridge, United States, in the North America region.

How does Mitobridge make money?

One revenue line is on record: web Design and Development Services.

Who are Mitobridge's main competitors?

Others on record are MPM Capital and Longwood Fund. Direct peers are Stealth BioTherapeutics, Pretzel Therapeutics, Minovia Therapeutics, CohBar, NRG Therapeutics, Khondrion and Abliva. Astellas Pharma is listed as a broad incumbent.

Does Mitobridge have an API?

No public API is recorded for Mitobridge.

What industry is Mitobridge in?

Mitobridge's product category is Mitochondrial Therapeutics. Its primary akta.pro industry code is HLAAAFAG, Microbiome Modulating Small Molecules & Antibiotic Alternatives, with a secondary code of HLAAAFAI, Microbiome Analytics, Sequencing & Bioinformatics Platforms. Its NAICS code is 541714 and its SIC code is 2835.

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Live signals
PR NewswireGenerian Achieves First Milestones in Mitobridge CollaborationGenerian Pharmaceuticals announced it has achieved the first research milestones for two programs under its collaboration with Mitobridge (a wholly-owned subsidiary of Astellas Pharma Inc.), focused on the stabilization or degradation of two unrelated transcription factors. The milestone payments were triggered by the successful identification of hit compounds using Generian's proprietary drug discovery platform, validated in functional assays as target protein stabilizers or degraders. Under the June 2022 collaboration agreement, Generian is eligible to receive additional milestone payments of approximately $180 million plus royalties on any global net sales.PR NewswireGenerian and Astellas Enter into Collaboration and Exclusive License Agreement to Discover and Develop Novel Small Molecules For Undruggable TargetsGenerian Pharmaceuticals and Mitobridge (a wholly owned subsidiary of Astellas Pharma) have entered into a collaboration and exclusive license agreement to discover and develop novel small molecules targeting previously undruggable therapeutic proteins. Under the agreement, Astellas will fund all clinical development, manufacturing, and commercialization activities while Generian is eligible to receive over $180 million in upfront and milestone payments, plus single-digit royalties on global net sales. The collaboration aims to leverage Generian's proprietary drug discovery platform to create first-in-class medicines for diseases with limited treatment options.PR NewswireU.S. FDA Grants Fast Track Designation to Astellas for the Development of ASP1128 for Patients at Risk for Acute Kidney InjuryThe U.S. Food and Drug Administration granted Fast Track designation to Astellas Pharma for ASP1128, an investigational drug candidate for preventing moderate to severe acute kidney injury in patients undergoing coronary artery bypass and/or valve surgery. ASP1128 is a selective PPARδ modulator being developed by Mitobridge (acquired by Astellas in 2018) and is currently in a Phase 2 proof-of-concept study enrolling approximately 220 patients across the United States. There are currently no drugs available for preventing or treating AKI, which occurs in up to 30% of cardiac surgery patients, with 2-6% requiring dialysis.PR NewswireAstellas Completes Acquisition of Mitobridge, Inc.Astellas Pharma Inc. completed its acquisition of Mitobridge, Inc. on January 23, 2018, making it a wholly owned subsidiary based in Cambridge, MA. Astellas paid $161.7 million for 100% equity (adjusted from the initial $225 million estimate), with additional payments of up to $225 million contingent on clinical development program progress. The transaction is expected to accelerate Astellas' research and development in diseases associated with mitochondrial dysfunctions and expand its pipeline of innovative treatment options.