Centre for Clinical Epidemiology & Evaluation

What Centre for Clinical Epidemiology & Evaluation does

The Centre for Clinical Epidemiology & Evaluation (C2E2) is an academic research center located within the Vancouver General Hospital Research Pavilion in Vancouver, British Columbia. It operates as a core research group within the Vancouver Coastal Health Research Institute (VCHRI) and maintains strong institutional links with the University of British Columbia. C2E2 undertakes research and training and provides evidence-based advice to advance a sustainable health system for British Columbians, covering clinical research, health economics, health policy and priority setting, health services research, planetary health, and qualitative and mixed-methods research. The center is staffed by 13 core faculty researchers, 13 research staff, and 8 trainees, with a stated headcount of 9 employees.

C2E2's primary technology product is ActionADE, a software application that enables frontline care providers to document adverse drug events and communicate this information across health sectors, with integration into BC's provincial drug information system (PharmaNet) and community pharmacy information systems. The center pursues a portfolio of major research projects including ActionADE ($2.4M), the Small Care Homes long-term care initiative ($1.3M), the COOLS Trial ($3M), and concussion studies, funded through competitive grants from Canadian agencies including CIHR, Health Research BC, BC Support, and foundations such as the Michael J. Fox Foundation and Terry Fox Foundation.

C2E2 operates as a nonprofit organization with no commercial product pricing. Its revenue model is grant-based, with research outputs made freely available through peer-reviewed publications, a public website, and events including monthly Spotlight presentations and Annual Lectures. The organization also engages in strategic partnerships with the BC Ministry of Health, the College of Pharmacists of BC, Lower Mainland Pharmacy Services, and CADTH at the national level. Distribution of research occurs through direct collaboration with health authorities, academic publication, and knowledge-exchange events serving healthcare system stakeholders and the academic community.

Name

Centre for Clinical Epidemiology & Evaluation

Legal name

Centre for Clinical Epidemiology & Evaluation

Website

https://c2e2.ca

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Short description

C2E2 is a Vancouver-based academic research center affiliated with Vancouver Coastal Health Research Institute and UBC that conducts clinical epidemiology, health economics, and health services research to inform a sustainable health system in British Columbia.

Ownership category

akta.pro rank

Product category

Health Services Research

NAICS

Scientific Research and Development Services (5417), Research and Development in the Physical, Engineering, and Life Sciences (54171)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro industry

PRIMARYHLAFAMAL

Clinical Research & Trial Central Laboratories

Healthcare & Life Sciences/Healthcare Providers & Systems/Clinical Laboratories

SECONDARYHLAGAEAL

Data Management, Reporting & Regulatory Submissions for Central Labs

Healthcare & Life Sciences/Life Science Tools & Services (CRO/CDMO/Lab Services)/Central Labs & Clinical Diagnostics Services (Trial Support)

Keywords

• Health services research
• Clinical epidemiology
• Health economics analysis
• Health technology assessment
• Evidence synthesis

Headquarters

HQ city

Vancouver

HQ country

Canada

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Others

Revenue model

1. Research Grant Funding: C2E2 operates as an academic research center primarily funded through competitive research grants from Canadian funding agencies including the Canadian Institutes of Health Research (CIHR), Health Research BC, BC Support, and foundation grants from organizations such as the Michael J. Fox Foundation and Terry Fox Foundation. Revenue supports research projects, faculty salaries, and operational costs.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels4 records

Core offering

C2E2 is an academic research center that conducts health services research and training, and provides evidence-based advice to advance a sustainable health system for British Columbians. The center operates across seven research domains (Clinical Research, Health Economics, Health Policy & Priority Setting, Health Services Research, Planetary Health, Qualitative and Mixed-Methods Research, and Reviews & Evidence Synthesis) and delivers a named technology product, ActionADE, a software application for adverse drug event documentation integrated with BC's PharmaNet system.

Product overview

The Centre for Clinical Epidemiology & Evaluation (C2E2) is a research center that undertakes research, training, and provides evidence-based advice to advance a sustainable health system for British Columbians. Rather than offering traditional commercial products, C2E2 conducts research across multiple domains including Clinical Research, Health Economics, Health Policy & Priority Setting, Health Services Research, Planetary Health, and Qualitative and Mixed-Methods Research. The main technology product is ActionADE, a software application for adverse drug event documentation and communication integrated with BC's PharmaNet system.

Differentiator

Problem solved

Functional benefit

Products and services

• ActionADE Software application that allows frontline care providers to document adverse drug events (ADEs) and communicate this information between providers and across health sectors (e.g., from hospitals to community pharmacies) to prevent repeat ADEs. Integrates with PharmaNet, BC's provincial drug information system, and with community pharmacy information systems.

Quantifiable outcome

• ActionADE project addresses 276,000 emergency department visits and 100,000 admissions annually in BC due to adverse drug events
• +2 more outcomes

Named customers1 record

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

Partnerships

Seven partnerships are on record, tiered core and major.

• Vancouver Coastal Health Research Institute (VCHRI)coreStrategic or Co-development PartnerC2E2 is one of the core research groups within VCHRI. This partnership provides institutional affiliation, administrative support, and integration with Vancouver Coastal Health's clinical environment, enabling translational research.
• University of British Columbia (UBC)coreStrategic or Co-development PartnerC2E2 maintains strong links with UBC, particularly the School of Population and Public Health. Faculty hold academic appointments and students participate in research training at C2E2.
• Vancouver Coastal Health (VCH)coreStrategic or Co-development PartnerC2E2 operates under VCH's governance structure and provides research support for VCH's healthcare delivery operations. The organization is located within VGH Research Pavilion.
• BC Ministry of HealthcoreStrategic or Co-development PartnerPartnered for ActionADE project integration with provincial drug information system (PharmaNet). The Ministry provides policy framework and provincial health information infrastructure for research implementation.
• Lower Mainland Pharmacy ServicescoreTechnology or IntegrationTechnical integration partner for ActionADE project, working to connect the application with provincial pharmacy information systems.
• College of Pharmacists of BCmajorStrategic or Co-development PartnerRegulatory partner for ActionADE project ensuring compliance with pharmacy practice standards and facilitating integration with community pharmacy systems.
• Canadian Agency for Drugs and Technologies in Health (CADTH)majorStrategic or Co-development PartnerNational HTA partner for the Improving the impact of HTA in Canada project, collaborating to better integrate HTA evidence with health system decision-making.

Scale indicators2 records

Recent moves5 records

Expansion highlights5 records

Regional players

• BC Centre for Disease Control (BCCDC): Provincial public health agency co-located in Vancouver, conducting epidemiological and health services research. Shares BC context, overlapping faculty, and population health research themes with C2E2.

Direct peers

• Clinical Trials Ontario (CTO): Ontario clinical trials enabling organization. Comparable in clinical research infrastructure, though more focused on operational trial enablement rather than academic research outputs.
• Centre for Health Economics and Policy Analysis (CHEPA), McMaster University: McMaster-affiliated centre focused on health economics and policy analysis. Strong methodological overlap with C2E2's health economics and priority-setting research streams.
• Population Health Research Institute (PHRI), McMaster University: Large Canadian clinical epidemiology and trials research institute. Comparable in clinical epidemiology methods and clinical trials delivery (e.g., COOLS Trial), though at substantially larger scale.
• Centre for Health Services and Policy Research (CHSPR), UBC: UBC-affiliated health services and policy research centre. Direct peer sharing the same university, overlapping faculty networks, and a near-identical mandate of health services and policy research in British Columbia.
• Institute of Health Economics (IHE): Alberta-based health economics and health technology assessment research organization. Closely comparable in HTA focus, health economics methodology, and policy advisory role to C2E2's HTA and health economics portfolio.
• Institute for Clinical Evaluative Sciences (ICES): Ontario's leading health services research institute using administrative health data to evaluate care delivery and outcomes. Comparable methodology and mandate to C2E2, scaled to a provincial Ontario context.
• Canadian Centre for Applied Research in Cancer Control (ARCC): Canadian network focused on health economics, cancer services, and policy research. Comparable applied health services research and HTA orientation, with overlapping investigator networks.

Broad incumbents

• Ottawa Hospital Research Institute (OHRI): Large hospital-affiliated research institute conducting clinical epidemiology, health services research, and trials. Comparable scope to C2E2 but operates at a much larger scale with broader mandate.

Others

• Canadian Agency for Drugs and Technologies in Health (CADTH): National HTA agency and active C2E2 partner. While not a competitor, CADTH represents a key ecosystem player whose priorities shape the demand environment for C2E2's HTA and health policy work.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/centre-for-clinical-epidemiology-&-evaluation

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Centre for Clinical Epidemiology & Evaluation