Cardiovascular Research Institute Dublin - CVRI

What Cardiovascular Research Institute Dublin - CVRI does

Cardiovascular Research Institute Dublin (CVRI Dublin) is an academic cardiovascular research institute established in 2019 within Mater Private Network Dublin in collaboration with RCSI University of Medicine and Health Sciences. It operates as a clinical research organization (CRO), an AI-enabled imaging core lab (PRECISE), a registry and real-world evidence platform, and an education/innovation hub. Its clinical research portfolio spans interventional cardiology, electrophysiology, structural heart disease, and heart failure, delivering first-in-human, investigator-initiated, sponsor-collaborative, and regulatory-grade studies for pharmaceutical and medical device sponsors. PRECISE Imaging Core Lab is the technological centrepiece, providing multimodality AI-powered cardiovascular imaging and analytics across echocardiography, coronary and structural CT, cardiac MRI, angiography, intravascular imaging (IVUS, OCT, NIRS), rhythm analysis, and haemodynamics, with proprietary capabilities in automated CT angiography reconstruction, zero-variability automated echocardiographic measurement, quantitative coronary angiography, and a cardiovascular digital twin combining patient data, physics models, and clinical records.

CVRI Dublin generates revenue through four streams: industry-sponsored clinical trials (Boston Scientific, Medtronic, Abbott, Novo Nordisk, Amgen, Teleflex, Terumo, Biotronik, Biosense Webster, LUMA Vision, Catheter Precision), academic/investigator-initiated research with device-company or grant funding, independent imaging core-lab services for academic partners such as Radboud University Medical Center, and registry and outcomes research supporting quality assurance and longitudinal follow-up. Pricing is not publicly disclosed; engagements are negotiated as bespoke research services funded by sponsors, grants, and institutional arrangements. The institute serves four primary customer segments: clinical trial sponsors, academic research partners, healthcare providers (Mater Private Network), and healthcare professionals reached through education programs such as the Dublin Cardiovascular Research Forum, Dublin Heart Summit, Women's Heart Summit 2026, and PCR Trials Book 2026.

The institute is led by Prof. Robert Byrne (Director of Cardiology, RCSI Chair) and Prof. Osama Soliman (Deputy Director, PRECISE Director), with Amy Carswell as Executive Director and a leadership team drawn from international training backgrounds (German Heart Centre Munich, Erasmus MC, Queen's University Belfast, Semmelweis University). Operations have scaled from five staff in 2020 to over 20, supported by Mater Private's high-volume clinical platform (over 5,000 coronary procedures and 18,000+ cardiology patients annually). Strategic differentiators include first-in-Ireland EHRA ERTC accreditation, Boston Scientific FARAPULSE Academy Centre of Excellence status, 91+ peer-reviewed publications including in Nature Reviews Cardiology (IF 44.2), and a European Innovation Council Transition Grant supporting HeartWise development.

Name

Cardiovascular Research Institute Dublin - CVRI

Legal name

Cardiovascular Research Institute Dublin

Website

https://cvridublin.ie

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

Product category

Cardiovascular Clinical Research Services

NAICS

Scientific Research and Development Services (5417), Medical Laboratories (621511), Diagnostic Imaging Centers (621512)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071)

akta.pro primary industry

Clinical CROs (Phase I–IV) (HLAGAAAA)

akta.pro secondary industries

Imaging & Cardiac Safety Core Labs (ECOG/EEG/ECG) (HLAGAAAJ), Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF), Central Laboratory & Clinical Trial Testing CROs (HLAGAAAE)

Keywords

• Academic clinical research organization
• Cardiovascular clinical trials
• Imaging core lab services
• Electrophysiology research
• Interventional cardiology studies

Headquarters

HQ city

Dublin

HQ country

Ireland

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Industry-Sponsored Clinical Trials: Revenue from pharmaceutical and medical device companies sponsoring clinical trials conducted at CVRI Dublin, including global industry collaborations with companies such as Boston Scientific, Medtronic, Abbott, Biotronik, and others.
2. Academic/Investigator-Initiated Research: RCSI-sponsored and investigator-initiated trials, often with external funding from device companies or research grants.
3. Core Lab Services: Independent imaging core lab services for blinded assessment of images from clinical trials conducted by academic partners such as Radboud University Medical Center.
4. Registry and Outcomes Research: Quality assurance and registry services supporting detailed lesion-level analysis and longitudinal follow-up in routine cardiovascular care.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels7 records

Core offering

CVRI Dublin operates as an academic clinical research organization (CRO) and AI-enabled imaging core lab embedded within Mater Private Network Dublin. The institute delivers first-in-human, investigator-initiated, sponsor-collaborative, and regulatory-grade cardiovascular clinical trials across interventional cardiology, electrophysiology, structural heart disease, and heart failure. Its PRECISE Imaging Core Lab provides multimodality, standardized, regulator-ready imaging endpoints supported by AI-enabled workflows and cardiovascular digital twin technology.

Product overview

CVRI Dublin operates as an integrated cardiovascular research platform structured around five key pillars: Clinical Trials & Academic CRO, AI-Enabled PRECISE Imaging Core Lab, Registries & Real-World Evidence, Education/Talent Development, and Innovation & Translation. The PRECISE Core Lab serves as the AI-enabled imaging centrepiece, providing standardized, regulator-ready assessments for clinical trials. The Academic CRO delivers end-to-end trial capabilities from design to publication. Registries capture longitudinal cardiovascular data across Mater Private Network. Educational offerings include the annual Dublin Heart Summit and PCR Trials Book 2026. The innovation arm develops AI-powered cardiovascular digital twins and clinical tools through programmes like HeartWise/RightHeartWise and TARA Project for evidence synthesis.

Differentiator

Problem solved

Functional benefit

Brands

• PRECISE Imaging Core Lab: AI-enabled cardiovascular imaging and analytics platform providing multimodality expertise across echocardiography, CT, cardiac MRI, angiography, and intravascular imaging.
• TARA Project
• FITTER Trial

Products and services

• PRECISE Imaging Core Lab AI-enabled cardiovascular imaging core lab providing precise, standardised, and regulator-ready assessments for trials, registries, and innovation programmes. Delivers multimodality expertise across echocardiography, CT, cardiac MRI, angiography, rhythm analysis, hemodynamics, and intravascular imaging, serving clinical trial sponsors and academic research partners.
• Clinical Trials & Academic CRO Full-service academic clinical research organization delivering first-in-human, investigator-initiated, sponsor-collaborative, and regulatory-grade studies across interventional cardiology, electrophysiology, structural heart disease, and heart failure for pharmaceutical and medical device sponsors.
• Registries & Real-World Evidence Prospective and retrospective cardiovascular registries supporting quality improvement, outcomes science, independent evaluation of therapies, and translational evidence generation. Includes PCI Outcomes Registry and MPN Atrial Fibrillation Registry for healthcare providers and sponsors.
• Innovation & Translation Programmes Clinically grounded innovation programmes spanning structural heart, heart failure, AI-enabled imaging, digital solutions, and cardiovascular digital twin development delivered in partnership with academia and industry for translational research.
• Dublin Heart Summit Annual educational summit bringing together national and international experts to share best practice and the latest research across cardiovascular specialties, serving clinicians, researchers, and industry partners.

Named customers12 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability7 records

Feature6 records

Partnerships

Eleven partnerships are on record, tiered core, major and strategic.

• RCSI University of Medicine and Health SciencescoreStrategic or Co-development Partner · 1 January 2019Formal collaboration established in 2019 for cardiovascular research. Prof. Robert Byrne serves as Chair of Cardiovascular Research at RCSI. The partnership provides academic credibility, research governance, and access to university resources for the institute.
• Mater Private NetworkcoreStrategic or Co-development PartnerCVRI Dublin is embedded within Mater Private Network Dublin and operates as part of the Heart and Vascular Centre. The institute benefits from access to Mater Private's patient volume, specialist clinicians, and clinical infrastructure. The partnership provides the primary operational platform for all research activities.
• Radboud University Medical CentercoreStrategic or Co-development PartnerAcademic partnership for FITTER trial where CVRI Dublin serves as the independent imaging core lab for blinded IVUS-NIRS assessment. This demonstrates CVRI's role as a trusted partner for high-quality core lab services.
• Boston Scientific CorporationmajorTechnology or IntegrationMultiple collaborative clinical trials including CYCLOPES (sponsor funding), NAVIGATE PF (FARAVIEW technology), SOCRATES (post-market surveillance), FARADISE and OPALISE (FARAPULSE registry), and HERMES. CVRI Dublin serves as a FARAPULSE Academy Centre of Excellence.
• Medtronic VascularmajorTechnology or IntegrationSponsor of PREVAIL GLOBAL clinical trial investigating the Prevail Drug-Coated Balloon for in-stent restenosis and small vessel disease.
• Abbott Medical DevicesmajorTechnology or IntegrationSponsor of BLAST-OFF clinical trial for the VOLT PFA System. First patient enrolled January 2026.
• LUMA VisionstrategicTechnology or IntegrationFirst-in-human partnership for VERAFEYE system development with Prof. Gabor Széplaki as PI. LUMINIzE trial completed with successful first-in-human procedures and first publication released January 2026.
• Irish Cardiac SocietystrategicStrategic or Co-development PartnerCollaborative partner for Dublin Heart Summit and Women's Heart Summit 2026, supporting education and knowledge sharing in cardiovascular medicine.
• Irish Heart FoundationstrategicStrategic or Co-development PartnerSupporting partner for Women's Heart Summit 2026, focused on addressing cardiovascular disease in women.
• BiotronikmajorTechnology or IntegrationFunder of DUBSTENT DIABETES trial investigating dual device treatment with drug-coated balloon and drug-eluting stent in diabetic patients.
• Biosense Webster, Inc.majorTechnology or IntegrationSponsor of SECURE observational post-marketing study for cardiac arrhythmia mapping and ablation devices.

Scale indicators14 records

Recent moves10 records

Expansion highlights7 records

Broad incumbents

• IQVIA: World's largest CRO with cardiovascular franchise across Phase I–IV and real-world evidence; competes for the same pharma CV outcomes studies (e.g., OCEAN(a)/Amgen, HERMES/Novo Nordisk) that CVRI supports as a site.
• ICON plc: Dublin-headquartered global CRO with cardiovascular and medical-device capabilities; same domestic Irish base and overlapping cardiovascular trial sponsor relationships make it the most natural broad-incumbent peer.
• Eurofins Scientific: Global lab services and central/coronary imaging core lab provider (via Eurofins CDMM and related units); relevant comparable for the central laboratory / imaging analysis portion of CVRI's offering.
• PPD (Thermo Fisher Scientific): Large global CRO with cardiovascular and clinical imaging core lab services; comparable full-service model targeting the same pharma/device sponsors as CVRI Dublin.
• Medpace: Mid-sized global full-service CRO with a strong cardiovascular and medical-device franchise; competes for the same Boston Scientific/Medtronic-sponsored device and CV outcomes trials that CVRI runs as a regional hub.

Others

• Synlab: European medical diagnostics and central laboratory operator; adjacent comparable for the central-laboratory and clinical-trial testing portion of CVRI's core lab services, though not a direct cardiovascular specialist.

Direct peers

• Cardialysis: Netherlands-based cardiovascular imaging core lab and clinical research organization specializing in cardiology imaging analysis (IVUS, OCT, QCA, echocardiography). Prof. Soliman previously held leadership roles at Cardialysis/Erasmus MC, making it the most directly comparable peer to CVRI's PRECISE Core Lab and academic CRO model.
• Clario (formerly ERT/Bioclinica): Global clinical trial technology and imaging core lab provider with deep cardiology imaging (echo, CMR, angiography) and digital endpoint capabilities; directly comparable to CVRI's PRECISE Core Lab for cardiovascular imaging endpoint delivery in global trials.
• Baim Institute for Clinical Research: US-based academic cardiovascular research organization running investigator-initiated and sponsor-collaborative CV trials with an embedded CRO model; highly comparable academic-CRO positioning.

Regional players

• CERC (Cardiovascular European Research Centre): European cardiovascular clinical research organization running multicenter cardiology trials; comparable academic CRO with similar first-in-human and device-trial focus, primarily serving Western/Central Europe rather than Ireland specifically.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/MaterPrivateHospital
• LinkedInlinkedin.com/company/cvridublin
• Instagraminstagram.com/cvri.dublin

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Cardiovascular Research Institute Dublin - CVRI