What 中山市创艺生化工程有限公司 does

Zhongshan Chuangyi Biochemical Engineering Co., Ltd. (中山市创艺生化工程有限公司 / CYBIO) is a privately held Chinese in-vitro diagnostics (IVD) manufacturer founded in 1999 and headquartered in Zhongshan, Guangdong Province, with a satellite R&D center in Shenzhen established in 2014. The company designs, manufactures, and sells diagnostic instruments and the corresponding consumable reagents for clinical laboratories and point-of-care settings. Its instrument portfolio spans the CYB-series of five-part differential hematology analyzers (CYB-5200, CYB-5500, CYB-6000, CYB-6800), the CYFIA-series and AFS-4000 dry immunofluorescence POCT analyzers, and an integrated all-in-one platform combining bidirectional-LIS hematology analysis with fluorescence immunoassay. The reagent portfolio covers hematology reagents, biochemistry reagents, immune-assay system reagents, urine sediment detection reagents, and a COVID-19 2019-nCoV IgM/IgG fluorescence immunochromatographic test kit. The company's core technical differentiator is an industry-first ultrasonic anti-clog method that clears counting apertures in 3–15 minutes, reducing downtime versus conventional systems.

The business operates a hybrid go-to-market model: direct sales support for key hospital and clinical-lab accounts, complemented by a national distributor network of 300+ dealers reaching 1,000+ terminal customers across China, plus international export channels covering the Middle East, West Asia, Africa, Latin America, and Eastern Europe (including Romania and Poland). Revenue is generated through hardware sales of instruments paired with recurring reagent consumables, which is the standard IVD razor-and-blade model. The company holds ISO 9001, ISO 13485, EU CE, and US FDA certifications, and is designated a National High-tech Enterprise with a 2019 Guangdong R&D innovation rating of A3 (top 2% province-wide). Manufacturing is conducted at a 15 mu (≈2.5-acre) factory in Zhongshan's National Health Industry Base, with a workforce of approximately 200 employees including 70 R&D staff, an in-house doctor workstation, and a provincial/municipal engineering technology research center.

The company has pursued an IPO initiative since 2016 and has historically expanded through internal R&D and product launches rather than M&A. Leadership is concentrated in founder He Linhui (何林辉), who serves as General Manager and has driven the firm's 21-year IVD focus. The most recent strategic pivot was a 2020 product portfolio expansion to include a COVID-19 rapid serology kit and emergency disinfectant production in response to the pandemic, alongside formal performance-management reforms and a planned hematology reagent production line renovation.

Name

中山市创艺生化工程有限公司

Legal name

中山市创艺生化工程有限公司

Website

https://gd-cy.com

Company type

Private

Founded year

1999

Operating status

Operating

Short description

Zhongshan Chuangyi Biochemical Engineering Co., Ltd. (CYBIO) is a privately held Chinese IVD manufacturer producing five-part differential hematology analyzers, POCT fluorescence immunoassay instruments, and biochemical/immune/urine reagents for hospital clinical laboratories and point-of-care settings, distributed through 300+ China dealers and export channels across emerging markets.

Ownership category

akta.pro rank

Headquarters

HQ city

Zhongshan

HQ country

China

HQ region

Asia

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Technology or R&D, Operations, Marketing or Sales

Revenue model

1. Hematology Analyzers and Reagents: Sale of 5-part differential hematology analyzers (CYB series) and compatible blood cell analysis reagents. Instruments sold alongside consumable reagent packages, creating recurring revenue from reagent restocking.
2. Biochemical Reagents: Biochemical analyzer reagents for clinical chemistry testing, sold as consumable reagents.
3. Immune Analyzer Reagents: System reagents and fluorescence immunochromatography reagent kits for immune analyzers, including COVID-19 IgM/IgG detection kit.
4. Urine Analysis Reagents: Urinary sediment detection reagents for urine analysis testing.
5. POCT Instruments and Reagents: Point-of-care testing instruments (CYFIA series, AFS-4000) and associated dry fluorescence immunoassay reagent kits for rapid bedside diagnostics.
6. Disinfectant Products: During the COVID-19 pandemic, the company pivoted to produce disinfectant products (84消毒液, 复方季铵盐消毒剂, 聚维酮碘消毒剂) to support epidemic control, donated valued at 300,000 yuan.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels4 records

Core offering

Zhongshan Chuangyi Biochemical Engineering Co., Ltd. (CYBIO) is an in-vitro diagnostics (IVD) manufacturer that designs, produces, and sells clinical laboratory instruments and reagents. The product portfolio includes five-part differential hematology analyzers (CYB-5200, CYB-5500, CYB-6000, CYB-6800), dry fluorescence immunofluorescence POCT analyzers (CYFIA-2000, CYFIA-3000, AFS-4000), an integrated bidirectional LIS hematology-immunoassay all-in-one platform, and a full reagent line covering hematology, biochemistry, immunoassay, urine analysis, and COVID-19 IgM/IgG detection.

Product overview

Zhongshan Chuangyi Biochemical Engineering Co., Ltd (中山市创艺生化工程有限公司 / CYBIO) is a professional in-vitro diagnostics (IVD) manufacturer offering a dual-track product portfolio: (1) diagnostic instruments — the CYB-series five-part differential hematology analyzers (CYB-5200, CYB-5500, CYB-6000, CYB-6800) featuring proprietary ultrasonic anti-clog technology; the CYFIA-series and AFS-4000 dry immunofluorescence POCT analyzers; and the integrated All-in-One platform combining bidirectional LIS hematology and fluorescence immunoassay in a single system; (2) IVD reagents — covering biochemistry analyzer reagents, hematology analyzer reagents, immune analyzer system reagents, urine sediment detection reagents, and the COVID-19 2019-nCoV IgM/IgG fluorescence immunochromatographic test kit. The company operates two R&D centers (Zhongshan and Shenzhen) and maintains nationwide sales coverage in China plus international distribution in the Middle East, Africa, Latin America, and Europe.

Differentiator

Problem solved

Functional benefit

Products and services

• CYB-5200 Five-Diff Hematology Analyzer A five-part differential hematology analyzer for automated blood cell counting and classification in clinical laboratory settings.
• CYB-5500 Five-Diff Hematology Analyzer A five-part differential hematology analyzer representing the company's flagship hematology instrument line for clinical blood cell analysis.
• CYB-6000 Five-Diff Hematology Analyzer A five-part differential hematology analyzer in the CYB series, designed for automated hematology testing in clinical settings.
• CYB-6800 Five-Diff Hematology Analyzer A five-part differential hematology analyzer featuring proprietary ultrasonic anti-clog technology that clears counting apertures in 3-15 minutes, with bidirectional LIS connectivity.
• CYFIA-2000 Dry Immunofluorescence Analyzer A dry fluorescence immunofluorescence analyzer for point-of-care testing, designed for rapid bedside or clinic-side diagnostic results.
• CYFIA-3000 Dry Immunofluorescence Analyzer A dry fluorescence immunofluorescence analyzer for POCT use, supporting single-channel testing workflows in clinical and point-of-care environments.
• AFS-4000 Full-Automatic Dry Immunofluorescence Analyzer A fully automatic dry fluorescence immunofluorescence analyzer designed for high-throughput clinical diagnostic testing at point of care.
• Two-Way LIS Hematology Analyzer – Fluorescence Immunoanalyzer All-in-One Instrument An integrated analysis platform combining five-diff hematology analysis with fluorescence immunoassay capabilities, featuring bidirectional LIS connectivity for seamless laboratory data management.
• Reagents for Chemistry (Biochemical) Analyzer Biochemical assay reagents compatible with chemistry analyzers, forming part of the company's IVD reagent portfolio.
• Reagents for Hematology Analyzer Reagents for use with hematology analyzers, including compatible consumables for the CYB series five-diff hematology instruments.
• Reagents for Immune Analyzer (System Reagents) System reagents designed for use with immune analyzer instruments, part of the company's integrated reagent portfolio.
• COVID-19 2019-nCoV IgM/IgG Fluorescence Immunoassay Test Kit A fluorescence immunochromatographic test kit for the qualitative detection of SARS-CoV-2 (2019-nCoV) IgM and IgG antibodies in blood samples, with clinical validation showing 97.1% IgM and 98.2% IgG positive rates.
• Reagents for Urine Analysis Urine sediment detection reagents (Class I medical devices) included in the company's IVD reagent product range.

Quantifiable outcome

• R&D innovation capability rated A3 (top 2% in Guangdong province, top 8 in Zhongshan city)
• +2 more outcomes

Named customers1 record

Segments2 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

Feature5 records

Scale indicators10 records

Recent moves9 records

Expansion highlights4 records

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key highlights7 records

Customer concentration

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about 中山市创艺生化工程有限公司