HPV Cancers Alliance

What HPV Cancers Alliance does

HPV Cancers Alliance (HPVCA) is a U.S. national nonprofit organization headquartered at PO Box 23075, New York, NY, founded by anal-cancer survivors Lillian Kreppel (Co-founder, President and CEO) and actress Marcia Cross (Co-founder and Chairperson). The organization is dedicated to reducing the burden of HPV through evidence-based education, prevention, and advocacy across all HPV-related cancers — anal, cervical, vaginal, vulvar, penile, and head and neck. Its offerings span content resources, survivor storytelling, provider-facing clinical materials, legislative advocacy, webinars, and community events, serving four primary personas: patients and survivors, caregivers and family members, healthcare professionals (with a specific gastroenterology focus), and the general public (including youth-focused programs such as Healthy Youth, Healthy Future).

The technology surface consists of two named core products. HPV Next Steps is a first-of-its-kind digital tool, built on REDCap, that provides anonymous, personalized guidance on HPV vaccination, screening, and cancer prevention via 2-3 inputs (age, sex assigned at birth, vaccination history); it is hosted externally at redcap.link/hpvnextsteps. The Conversation Case (GI Provider Toolkit) is an HPV-focused clinician resource with downloadable PDFs covering evidence-based guidance, intake forms, and posters, designed to counter stigma and advance detection in gastroenterology practice. Distribution is primarily digital (website at hpvca.org, Facebook, X, Instagram, YouTube, LinkedIn) with in-person community events including an annual Soirée in the City fundraiser and Town Hall gatherings.

HPVCA's business model is donation-driven: the organization is a registered nonprofit with 12 employees that provides all educational resources, digital tools, and clinical toolkits free of charge, and accepts contributions through a Stripe-powered donation portal on its website. The organization also highlights the potential public-health impact of universal HPV vaccination — approximately 1 million cancer diagnoses and nearly 500,000 deaths preventable annually, equivalent to roughly 5% of the world's cancers — as its core mission metric. It operates within a single national geographic scope (United States) and holds the GuideStar Platinum Seal of Transparency from Candid.

Name

HPV Cancers Alliance

Legal name

HPV Cancers Alliance

Website

https://hpvalliance.org

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Short description

HPV Cancers Alliance is a U.S. national nonprofit that delivers evidence-based education, prevention, and advocacy across all HPV-related cancers, serving patients, caregivers, healthcare professionals, and the public through digital tools, provider toolkits, and community events.

Ownership category

akta.pro rank

Product category

Cancer Prevention & Patient Advocacy

NAICS

Other Social Advocacy Organizations (813319), Social Advocacy Organizations (8133), Individual and Family Services (6241)

SIC

Services-Social Services (8300)

akta.pro primary industry

Public–Private Partnerships (PPPs) for Global Health (HLAJAOAD)

akta.pro secondary industries

Global Health Research, Clinical Trials & Product Development Partnerships (PDPs) (HLAJAOAM), Immunization & Vaccine Access Partnerships (Global Vaccine Alliances) (HLAJAOAF)

Keywords

• Cancer prevention education
• Patient advocacy services
• Healthcare provider toolkits
• Nonprofit health organization
• HPV awareness campaigns

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Donations and Charitable Contributions: The organization accepts donations through its website (powered by Stripe) and promotes individual giving as a primary funding mechanism. Donors are encouraged to invest in a healthier future and support the elimination of HPV-related cancers.

Go-to-market motion1 record

Distribution channels4 records

Marketing channels9 records

Core offering

HPV Cancers Alliance is a national nonprofit delivering evidence-based education, prevention resources, and advocacy focused on HPV and HPV-related cancers. Its core products include HPV Next Steps, a free, anonymous, personalized digital tool that guides individuals on vaccination and screening, and The Conversation Case (GI Provider Toolkit), a clinical resource for gastroenterology providers to counter stigma and improve HPV-related cancer care.

Product overview

HPV Cancers Alliance is a national nonprofit organization offering a portfolio of educational products and resources focused on HPV awareness, prevention, and cancer care. The core offerings include HPV Next Steps, a personalized digital guide for individual users seeking vaccination and screening guidance, and The Conversation Case (a GI Provider Toolkit) delivering evidence-based resources for healthcare professionals. These products are complemented by comprehensive educational content covering HPV information, cancer treatments, survivor stories, self-advocacy resources, legislative action materials, newsletters, webinars, and community events.

Differentiator

Problem solved

Functional benefit

Brands

• HPV Next Steps: A first-of-its-kind, easy-to-use virtual tool designed to support individuals in taking charge of their health regarding HPV prevention and care. Offers personalized guidance based on age, sex assigned at birth, and vaccination history.

Products and services

• HPV Next Steps A first-of-its-kind, free, anonymous, personalized digital tool that provides tailored guidance on HPV vaccination, screening, and cancer prevention based on 2-3 quick questions about age, sex assigned at birth, and vaccination history. Built on REDCap and intended for individuals seeking to take charge of their HPV prevention and care decisions.
• The Conversation Case (GI Provider Toolkit) An HPV-focused toolkit for gastroenterology providers offering evidence-based guidance, key facts, issue framing, unmet needs, and actionable steps to advance prevention, detection, and dialogue in clinical practice. Includes downloadable PDFs for The Conversation Case, intake forms, and posters to help clinicians counter stigma and promote stigma-free patient care.

Quantifiable outcome

• Universal HPV vaccination could prevent ~1 million cancer diagnoses and ~500,000 deaths annually (5% of world cancers)

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature2 records

Partnerships

Two partnerships are on record, tiered minor and core.

• The ANCHOR StudyminorOthersThe ANCHOR Study is referenced as a resource on the HPV Cancers Alliance website, suggesting a informational partnership or referral relationship. The ANCHOR Study likely relates to HPV-related cancer research or screening initiatives.
• HPV Next Steps (Powered by REDCap)coreTechnology or IntegrationThe HPV Next Steps digital tool is built using REDCap (Research Electronic Data Capture), a secure web application for building and managing online surveys and databases. This technology partnership enables the organization's personalized prevention guidance tool.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Oral Cancer Foundation: National nonprofit dedicated to oral cancer awareness, education, and patient support. Overlaps with HPVCA's head and neck cancer content and shares the patient-survivor-caregiver audience.
• Cervivor: Nonprofit dedicated to cervical cancer awareness, survivor advocacy, and HPV-related education. Directly competes for the same patient, caregiver, and survivor audiences as HPV Cancers Alliance, with a deeper specialization in cervical cancer.
• Anal Cancer Foundation: Nonprofit focused on anal cancer prevention, early detection, and patient support. Closely aligned with HPV Cancers Alliance's founding story (co-founders are anal cancer survivors) and target survivor segment.
• The Farrah Fawcett Foundation: Foundation focused on HPV-related cancer research and patient assistance, with a celebrity-driven brand. Direct comparable in mission and celebrity-led advocacy model to HPV Cancers Alliance.
• National HPV Vaccination Roundtable: National coalition coordinated by the American Cancer Society focused on increasing HPV vaccination rates through healthcare provider and system engagement. Highly comparable mission and target audience as HPV Cancers Alliance, though with a sharper focus on vaccination policy and provider adoption.

Emerging players

• Stupid Cancer: Nonprofit focused on young adult cancer advocacy, including HPV-related cancers. Shares a digital-first, community-driven advocacy model with similar survivor storytelling and awareness-building approach.
• Foundation for Women's Cancer: Nonprofit focused on gynecologic cancers, including cervical, ovarian, uterine, and vulvar cancers. Overlaps with HPVCA's women's cancer content but with a broader gynecologic focus rather than HPV-specific framing.

Broad incumbents

• American Cancer Society: Large nationwide cancer advocacy organization with significant HPV-related programming. Does not specialize in HPV but is a dominant donor-facing incumbent in the broader cancer advocacy space where HPV Cancers Alliance competes for funding and attention.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/HPVAlliance
• YouTubeyoutube.com/channel/UCSKX3c-w_57ZFpwyN0kaX4Q
• Facebookfacebook.com/HPVCancersAlliance
• LinkedInlinkedin.com/company/hpv-alliance
• Instagraminstagram.com/hpvcancersalliance/?hl=en

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about HPV Cancers Alliance