Institute for Human Genetics at UCSF

What Institute for Human Genetics at UCSF does

The Institute for Human Genetics (IHG) at UCSF is a public academic institute founded in 2006 and operated under The Regents of the University of California. Headquartered in San Francisco, California, IHG serves as UCSF's designated central hub for human genetics activity, with faculty spanning all four UCSF schools (Dentistry, Medicine, Nursing, and Pharmacy) and numerous departments within them. The institute is governed by Nadav Ahituv, PhD, who assumed the directorship on January 23, 2023, succeeding inaugural director Neil Risch; an interim directorship by Ophir Klein, MD, PhD is also recorded in the leadership record.

IHG's primary operating asset is a CLIA-certified (CLIA #05D2080584) Genomics Core facility located in the Mt. Zion Cancer Research building. The core delivers fee-for-service genomic and computational services, including Illumina NovaSeq 6000 sequencing (RNA-seq, whole genome, whole exome, targeted DNA), Applied Biosystems Axiom SNP/indel genotyping, single-cell RNA-seq on the 10X platform, spatial transcriptomics (MERFISH, Xenium), DNA extraction, and bioinformatics consulting. An in-house high-performance computing cluster with Infiniband GPFS fast storage and near-line SAS tier-3 archival storage supports downstream analysis. Clinical-grade services include CLIA-certified exome sequencing, genome sequencing, and variant confirmation.

The institute operates a community-led GTM motion primarily through internal UCSF research community access, supplemented by external fee-for-service work for academic and industry investigators at published rates (with 26% Facilities and Administration and 15% Surplus Revenue overhead added to external pricing). Ancillary revenue streams and impact channels include the Genotech Symposium co-hosted with the UCSF Broad Center, an IHG Seminar Series (including the Charles Epstein Distinguished Seminar Series), Lunch and Learn technology seminars with vendors such as Illumina, PacBio, Oxford Nanopore, and 10x Genomics, bioinformatics workshops with the UCSF Library Data Science Initiative and Gladstone Institute, and educational programs including the Medical Genetics & Genomics Residency, the Genetic Counseling Program (founded 2021), and the IHG Education Committee (established 2018). No venture or private equity funding is involved; the institute is supported by state appropriations, grants, philanthropy, and endowed chairs.

Name

Institute for Human Genetics at UCSF

Legal name

The Regents of the University of California

Website

https://humangenetics.ucsf.edu

Company type

Public

Founded year

2006

Operating status

Operating

Headcount range

1–10 employees

Short description

The Institute for Human Genetics at UCSF is a public academic institute founded in 2006 that operates as the central hub for human genetics research, training, and clinical translation across all four UCSF schools. It delivers fee-for-service genomics through a CLIA-certified core serving UCSF researchers and external investigators.

Ownership category

akta.pro rank

Product category

Genomics Services

NAICS

Medical Laboratories (621511), Medical and Diagnostic Laboratories (6215), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Medical Laboratories (8071), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Molecular Diagnostics & Genomics Laboratories (HLAFAMAE)

akta.pro secondary industries

Transcriptomics & Gene Expression Profiling Services (HLAGANAE), Bioinformatics, Multi-Omics Data Analysis & Interpretation Services (HLAGANAI), Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD)

Keywords

• Genomics sequencing services
• Clinical genetic testing
• Bioinformatics consulting
• Human genetics research
• Academic core facility

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Infrastructure, Supply Chain, Operations

Revenue model

1. Genomics Services Revenue: Fee-for-service model providing Illumina sequencing, whole genome sequencing, SNP genotyping, and DNA extraction services to UCSF researchers and external investigators. Internal and external pricing tiers with Facilities and Administration overhead applied to external rates.
2. Clinical Genetics Services: CLIA-certified clinical services including targeted sequencing and whole genome sequencing for clinical applications through the genomics core.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

The Institute for Human Genetics (IHG) at UCSF operates a CLIA-certified genomics core facility delivering Illumina NovaSeq 6000 next-generation sequencing, Applied Biosystems Axiom genotyping, DNA extraction, and bioinformatics consulting to UCSF researchers and external investigators. It functions as the central coordinating hub for human genetics research, training, and clinical translation spanning all four UCSF schools (Dentistry, Medicine, Nursing, Pharmacy). The institute supplements these services with HPC data storage, single-cell and spatial transcriptomics, CLIA-certified clinical sequencing, and educational workshops.

Product overview

The Institute for Human Genetics (IHG) at UCSF operates as a CLIA-certified genomics core facility offering a comprehensive suite of genomic services. The core services include Illumina NovaSeq 6000 sequencing (for RNA-seq, whole genome, whole exome, and targeted DNA sequencing), Applied Biosystems Axiom Genotyping for SNP/indel analysis, DNA extraction, and genomics consulting. Clinical services include CLIA-certified exome sequencing, genome sequencing, and variant confirmation. Specialized offerings encompass single-cell RNA-seq on the 10X platform and ready-to-sequence library processing. Computational infrastructure includes HPC cluster access with fast and archival storage. Additionally, IHG provides bioinformatics education through workshops on R Bioconductor, Galaxy platform, CellRanger, and Seurat analysis.

Differentiator

Problem solved

Functional benefit

Products and services

• Illumina NovaSeq 6000 Sequencing Next-generation sequencing service using the NovaSeq 6000 platform for RNA-seq, whole genome, whole exome, and targeted DNA sequencing with SP, S1, S2, and S4 flow cell options, offered to UCSF researchers and external investigators on a fee-for-service basis.
• Applied Biosystems Axiom Genotyping High-throughput SNP and indel genotyping service using Beckman Coulter Biomek FxP Target Prep Express and Applied Biosystems GeneTitan Multi-Channel Instrument for targeted structural variants and microbial detection.
• DNA Extraction DNA extraction service preparing high-quality DNA samples from blood (up to 10 ml) and saliva for downstream genomics applications.
• Genomics Consulting Expert consultation services for project planning, sequencing strategy, and data analysis interpretation delivered by experienced clinical exome sequencing specialists.
• CLIA-Certified Exome and Target Sequencing CLIA-certified clinical exome and targeted sequencing service for diagnostic applications with variant interpretation, delivered through the genomics core facility.
• CLIA-Certified Genome Sequencing CLIA-certified whole genome sequencing service for comprehensive clinical genomic analysis.
• CLIA-Certified Variant Confirmation CLIA-certified variant confirmation service for validating genetic findings in a clinical laboratory setting.
• Single-cell RNA Sequencing (10X Platform) 10X platform single-cell RNA sequencing service requiring 50ul at 1,000 cells/ul in 1X PBS with 0.04% BSA, with typical turnaround of 4-6 weeks.
• Ready-to-Sequence Library Processing Sequencing library preparation service for pre-prepared libraries requiring 20ul at minimum 15nM with Bioanalyzer traces.
• HPC and Data Storage High-performance computing cluster access with CPU time, fast storage (Infiniband GPFS), and archival storage (near-line SAS) for genomics data analysis.
• Bioinformatics Workshops Educational workshops covering DNA variant analysis with R Bioconductor, RNA-seq analysis, and single-cell RNA-seq analysis using Seurat, co-hosted with the UCSF Library Data Science Initiative and Gladstone Institute.

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability13 records

Feature3 records

Partnerships

Five partnerships are on record, tiered core.

• Gladstone InstitutecoreStrategic or Co-development PartnerGladstone Institute collaborates with IHG on workshops and educational programs in genomics and bioinformatics, including intermediate R: RNAseq Analysis, Intro to RNA-seq analysis, Single Cell Analysis Hands-on Workshop, and Whole Genome & Exome analysis workshops.
• UCSF Library Data Science InitiativecoreStrategic or Co-development PartnerPartnership with UCSF Library's Data Science Initiative to offer bioinformatics workshops including DNA Variant Analysis with R Bioconductor, RNA-Seq Analysis with R Bioconductor, and Single-cell RNA-seq Analysis with Bioconductor.
• UCSF Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell ResearchcoreStrategic or Co-development PartnerCo-host the annual Genotech Symposium with UCSF IHG, bringing together academic researchers, industry leaders, and the genetics and genomics community for collaboration and scientific exchange.
• Elena Flowers, PhD, RN - UCSF School of NursingcoreStrategic or Co-development PartnerDirector of Genomics Specialty Focus Area at UCSF School of Nursing, integrating genomics education throughout nursing curriculum with required courses N294A, N294B, N294C covering human genomics, clinical implications, and applications across the lifespan.
• Bani Tamraz, PharmD, PhD - UCSF School of PharmacycoreStrategic or Co-development PartnerDiscovery Group Director for Genetics & Genomics at UCSF School of Pharmacy, leading pharmacogenomics integration throughout the PharmD curriculum including inquiry sessions, discovery projects, and clinical rotations.

Scale indicators2 records

Recent moves6 records

Expansion highlights5 records

Market position

Competitive moat4 records

Customer concentration

• Xx.com/IHG_at_UCSF
• YouTubeyoutube.com/watch?v=Ki11ZSjMMy0
• LinkedInlinkedin.com/company/institute-for-human-genetics-at-ucsf

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Institute for Human Genetics at UCSF