Institute of Animal Physiology and Genetics, Academy of the Sciences of the Czech Republic

What Institute of Animal Physiology and Genetics, Academy of the Sciences of the Czech Republic does

The Institute of Animal Physiology and Genetics of the Academy of Sciences of the Czech Republic (Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.) is a public research institution operating under the Academy of Sciences of the Czech Republic. It conducts research in animal physiology, developmental biology, molecular genetics, regenerative medicine, and related biomedical fields, organized across more than fifteen specialized laboratories and the PIGMOD Center at Liblice Castle. The institute employs approximately 200 researchers and staff across three sites — Liběchov (headquarters), Prague-Krč, and Brno — and is funded primarily through Czech national grants (GAČR, MZČR, MŠMT, TAČR, MZe) and EU programs including Horizon Europe.

Its core technological capabilities span CRISPR/Cas genome editing, transgenic animal model development in mice, minipigs, and rabbits, molecular biology, genomics, proteomics, and advanced imaging. Proprietary assets include the TgHD transgenic minipig model for Huntington's disease (carrying the mutant human huntingtin fragment) and the MeLiM melanoma-bearing minipig, both developed at the PIGMOD Center and used in preclinical studies that supported European clinical trials. The institute also operates advanced instrumentation including Sciex TripleTOF 5600+ and QTRAP 5500 mass spectrometers, Leica SP5 confocal microscopy, BD FACS Aria cell sorting, light-sheet and electron microscopy, and dedicated surgical facilities.

Commercially, the institute offers contract research services, animal model access, specialized laboratory and equipment rental, and know-how licensing (covering CRISPR/Cas methods, stem cell therapy, novel surgical approaches, genomics, and developmental biology) to academic institutions, hospitals, and pharmaceutical and biotechnology companies. Pricing is set on a pay-as-you-go basis upon request. Distribution is exclusively through direct contracted research cooperation agreements, with no commercial channel structure; the institute markets its capabilities primarily through scientific publications, conferences, public outreach events (Night of Scientists, Children's Day), press releases, and the ReConnect researcher-support program. Recognition includes the European Commission's HR Excellence in Research Award (2021), Otto Wichterle Premium (2024), and multiple Czech learned-society prizes.

Name

Institute of Animal Physiology and Genetics, Academy of the Sciences of the Czech Republic

Legal name

Ústav živočišné fyziologie a genetiky Akademie věd ČR, v. v. i.

Website

https://iapg.cas.cz

Company type

Private

Operating status

Operating

Headcount range

51–100 employees

Short description

The Institute of Animal Physiology and Genetics (ÚŽFG AV ČR) is a Czech public research institution that develops unique transgenic minipig and mouse disease models and offers contract research, preclinical testing, and advanced proteomics/imaging services to academic and pharmaceutical partners.

Ownership category

akta.pro rank

Product category

Biomedical Research Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071), Services-Testing Laboratories (8734)

akta.pro industry

PRIMARYHLAMANAL

Clinical Research, Trials & Translational Services (Veterinary Regenerative)

Healthcare & Life Sciences/Veterinary & Animal Health/Regenerative Medicine for Animals

SECONDARYEDAHAGAI

Biomedical Sciences & Medical Research Institutes (University-Based)

Education/Higher Education (Colleges & Universities)/Medical & Health Sciences Universities

SECONDARYHLAMADAF

Reproductive & Endocrinology Diagnostics (Fertility, Hormones)

Healthcare & Life Sciences/Veterinary & Animal Health/Veterinary Diagnostics (Labs & Imaging)

Keywords

• Animal physiology research
• Transgenic animal models
• Biomedical research services
• Developmental biology studies
• Molecular biology research

Headquarters

HQ city

Liběchov

HQ country

Czechia

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure

Pricing tiers

Distribution channels1 record

Marketing channels5 records

Core offering

The Institute of Animal Physiology and Genetics conducts scientific research in animal physiology, genetics, developmental biology, and molecular biology. It supplies biomedical research services to research institutions and pharmaceutical clients, including proprietary transgenic animal models (minipigs, mice, rabbits), surgical services, access to advanced research equipment, and transfer of know-how.

Product overview

The Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic (ÚŽFG) is a public research institution offering specialized biomedical research services. Its core offerings include unique animal models (MeLiM minipig for melanoma, TgHD minipig for Huntington's disease, transgenic mouse models, and rabbit models), surgical services with advanced operating facilities, access to sophisticated research equipment including mass spectrometers and confocal microscopes, and expert know-how in developmental biology, CRISPR/CAS methods, genomics, proteomics, and preclinical testing. The institute operates the PIGMOD Center specializing in swine biomedical models and provides contract research services to external partners.

Differentiator

Problem solved

Functional benefit

Brands

• PIGMOD: Center focused on pig models for biomedical research, including minipig models for Huntington's disease, cancer research, and other biomedical applications.

Products and services

• MeLiM Minipig Model

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Ten partnerships are on record, tiered core and minor.

• Ludwig-Maximilians-Universität München (LMU)coreStrategic or Co-development Partner · 1 October 2024Joint participation in the EU Horizon Europe project NHPig (Reducing Non-Human Primates in Non-Clinical Safety Assessment: The European Initiative on Minipig and Micropig Models). LMU is the project leader; Ing. Zdenka Ellederová, Ph.D. from ÚŽFG AV ČR serves as co-investigator. The project runs from October 2024 to September 2029 and focuses on improving the use of minipig and micropig models for non-clinical safety studies.
• ExRegMed Consortium (Excellence in Regenerative Medicine)coreStrategic or Co-development Partner · 1 October 2023ÚŽFG AV ČR is a partner in the ExRegMed project (Excelentní výzkum v regenerativní medicíně), funded by OP JAK. The project involves multiple Czech institutions led by Ústav experimentální medicíny AV ČR. ÚŽFG contributes research under direction No. 3 – Retinal degenerative diseases, led by Prof. Jan Motlík.
• PIGMOD Center (Centre for Pig Models)coreStrategic or Co-development PartnerThe PIGMOD Center at the Liblice Castle is a specialized research center of ÚŽFG AV ČR dedicated to pig models of human diseases. It organizes scientific workshops and international conferences, and collaborates with Norwegian Funds on project funding. The center develops and works with unique minipig models including TgHD and MeLiM.
• Česká zemědělská univerzita v Praze (Czech University of Life Sciences Prague)minorStrategic or Co-development PartnerCo-research partnership in MZe project QK22010270 on optimization of managed reproductive performance in dairy cattle. Doc. Ing. Luděk Stádník Ph.D. is the principal investigator, with Mgr. Tereza Toralová, Ph.D. from ÚŽFG AV ČR as co-investigator.
• Univerzita Karlova (Charles University)minorStrategic or Co-development PartnerMultiple collaborative projects including LUAUS23052 (interdisciplinary research on anaerobic fungi with University of California Santa Barbara), LTAUSA projects with UC San Diego, and various MŠMT INTER-EXCELLENCE projects. ÚŽFG researchers serve as co-investigators in projects led by Charles University.
• Akademie věd České republiky (Academy of Sciences of the Czech Republic)coreStrategic or Co-development PartnerÚŽFG AV ČR is a public research institute (v. v. i.) under the Academy of Sciences of the Czech Republic. The AV ČR provides institutional funding, strategic oversight, and collaborative platforms including the AV ČR Bulletin and AV ČR annual events.
• Všeobecná fakultní nemocnice v Praze (General University Hospital in Prague)minorStrategic or Co-development PartnerCollaboration in MZČR project NW24-10-00118 on porous gyroid surface structures for implant stability in osteoporotic bone. MUDr. MDDr. Martin Bartoš, Ph.D. is the principal investigator, with MVDr. Jana Juhásová, Ph.D. from ÚŽFG AV ČR as co-investigator.
• Masaryk University (Masarykova univerzita)minorStrategic or Co-development PartnerMultiple collaborative projects including MZČR project on Bardet-Biedl syndrome (with Mgr. Michaela Bosáková as co-investigator), INTER-COST project on senescence and proteases, and various other MŠMT and GAČR projects with researchers from both institutions.
• Fakultní nemocnice Ostrava (University Hospital Ostrava)minorStrategic or Co-development PartnerCollaboration in MZČR project NW24-10-00204 on orofacial anomalies in correlation with oncological diseases. Doc. RNDr. Marcela Buchtová, Ph.D. from ÚŽFG AV ČR is the principal investigator.
• Středočeské Inovační Centrum (Central Bohemian Innovation Center)minorStrategic or Co-development PartnerCollaboration through MERIT program (Mobility Programme for Excellence in Research, Innovation and Technology) launched January 2023. Projects include 'Vzory rediploidizace genomu v neopolyploidech' led by Dr. Vladimir Trifonov and 'Clihavole' project led by Lison Margot Josepha Zunino.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Market position

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/institute-of-animal-physiology-and-genetics-academy-of-the-sciences-of-the-czech-republic

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Institute of Animal Physiology and Genetics, Academy of the Sciences of the Czech Republic