Eckert & Ziegler Radiopharma Inc

What Eckert & Ziegler Radiopharma Inc does

Eckert & Ziegler Radiopharma Inc is the US operating subsidiary (Wilmington, Massachusetts) of Eckert & Ziegler SE's Medical segment, operating as a vertically integrated platform serving nuclear medicine, radiopharmaceutical manufacturing, and radiation therapy markets. The company operates four business units: Radiopharma (radionuclides and contract manufacturing including GalliaPharm Ge-68/Ga-68 generators, Yttriga Y-90 chloride, Lutetium-177, and Actinium-225); Lab Devices (Modular-Lab radiosynthesis systems, MiniScanPRO and AR-2000 quality control scanners, and GMP-compliant software via Eckert & Ziegler Eurotope); Hot Cells (customized radiation protection and in-cell equipment via Isotope Technologies Dresden, 500+ realized projects); and Radiation Therapy (brachytherapy products including I-125 prostate seeds and Ru-106 ophthalmic plaques via Eckert & Ziegler BEBIG).

The underlying technology centers on the Modular-Lab cassette-based radiosynthesis platform — featuring the Modular-Lab Standard (tubing-based R&D system), PharmTracer (cassette-based routine production), and eazy (compact radiometal synthesizer using pressure-based liquid transfer) — supported by GMP-compliant software with 21 CFR Part 11 and GAMP 5 compliance, and a portfolio of 500+ installed synthesis systems and 2,500+ analytical devices globally. Manufacturing spans GMP facilities in Berlin and Braunschweig (Germany), Wilmington (USA), and a newly opened joint venture site in Jintan, Changzhou (China).

The business model combines direct B2B enterprise sales of hardware (synthesizers, quality control equipment, hot cells, brachytherapy implants), consumable revenues (sterile gamma-irradiated Modular-Lab cassettes with 18-month shelf life), radionuclide sales (GMP and chemical grade), and professional services including contract manufacturing, GMP suite rental, radiopharmaceutical development, and regulatory support. Customers span pharmaceutical enterprises (Bayer, Sirtex Medical, Curium), biotech startups (Curasight, Pentixapharm, Octreopharm/Ipsen), and research institutions (MURR, HZDR, VTT). Pricing is not publicly disclosed and is quote-based; revenue mechanics depend on long-term supply agreements for radionuclides and major engineering/install contracts for hot cells and synthesis systems.

Name

Eckert & Ziegler Radiopharma Inc

Legal name

Eckert & Ziegler Radiopharma GmbH

Website

https://medical.ezag.com

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Short description

Eckert & Ziegler Radiopharma Inc is the US operating subsidiary of Eckert & Ziegler SE's Medical segment, providing GMP radiopharmaceutical manufacturing, radionuclides (Ga-68, Y-90, Lu-177, Ac-225), Modular-Lab radiosynthesis systems, hot cell engineering, and brachytherapy products to pharmaceutical companies, biotechs, and research institutions.

Ownership category

akta.pro rank

Product category

Radiopharmaceuticals and Nuclear Medicine Equipment

NAICS

Pharmaceutical and Medicine Manufacturing (3254), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (3345)

SIC

Electromedical & Electrotherapeutic Apparatus (3845), Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047), Laboratory Analytical Instruments (3826)

akta.pro primary industry

Radiopharmaceutical Manufacturing & CDMO (Synthesis, GMP, Packaging, QA/QC) (EUAKAIAC)

akta.pro secondary industries

Radiopharmaceutical & Nuclear Medicine Distributors (HLAIAJAI), Nuclear Medicine Imaging Tracers & PET/SPECT Supply Chain (FDG, Ga-68, logistics/cold chain) (EUAKAIAE), Radionuclide Supply Chain & Logistics (Shielding/Transport/Distribution) (HLAIAGAH), Radiation Therapy Isotopes & Sources (Brachytherapy seeds, sealed sources for oncology) (EUAKAIAD), Radiopharmacy Compounding & Dispensing (Hospital/Commercial) (HLAIAGAE)

Keywords

• Radiopharmaceutical manufacturing
• Nuclear medicine products
• Radiosynthesis systems
• Hot cell engineering
• Brachytherapy devices

Headquarters

HQ city

Wilmington, Massachusetts

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Technology or R&D, Personnel, Infrastructure, Marketing or Sales

Revenue model

1. Radionuclide and Radiopharmaceutical Sales: Sale of radiopharmaceuticals and radiochemicals including Ge-68/Ga-68 generators (GalliaPharm), Yttrium-90 (Yttriga), Lutetium-177, Actinium-225, and other radionuclides for research, diagnostic, and therapeutic applications. Also includes sale of radiochemicals in GMP and chemical grade.
2. Lab Device Sales and Service: Sale and service of Modular-Lab synthesis systems (Standard, PharmTracer, eazy), quality control equipment (MiniScanPRO, AR-2000, HPLC), associated software, and disposable cassettes. Service includes Modular-Lab Life Support Program (Basic, Basic-Pro, Premium tiers) covering maintenance, remote support, and training.
3. Hot Cell and Engineering Solutions: Design, engineering, manufacturing, installation, and testing of customized hot cells and in-cell equipment for healthcare, industry, and research institutions. Covers alpha, beta, and gamma shielding solutions. Services include full project management and training.
4. Contract Manufacturing Organization (CMO) Services: Clinical and commercial supply for projects using alpha, beta, or gamma radiation. Services span from early development through commercial distribution, including radiolabeled pharmaceuticals, GLP and cGMP-compliant production infrastructure, and regulatory support. Also encompasses GMP suite rental with equipped space and experienced personnel.
5. Radiopharmaceutical Development Services: Support for early development and pre-clinical stages. Based on specified biomolecules and radioisotopes, develops robust radioconjugates, optimizes manufacturing and testing methods. Includes process design, scale-up, automation, and validation for PET tracers, kits, and radiopharmaceuticals.
6. Radiation Therapy Products: Brachytherapy products including permanent prostate implants (I-125 seeds in loose and stranded form), ophthalmic applicators (ruthenium-106 plaques), and radiotherapy accessories (gold markers). Products supported by patient information services, aftercare passports, and implantation cards.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels6 records

Core offering

Eckert & Ziegler Medical manufactures and supplies radioisotopes and radiopharmaceuticals (Ge-68/Ga-68 generators, Y-90, Lu-177, Ac-225), radiosynthesis and quality control laboratory equipment (Modular-Lab systems, TLC scanners, HPLC detectors), customized hot cells and radiation protection solutions, and brachytherapy devices (I-125 prostate seeds, Ru-106 ophthalmic plaques). The company also provides contract manufacturing organization (CMO) services, GMP suite rental, radiopharmaceutical development, and regulatory support for clinical and commercial supply of radiopharmaceuticals.

Product overview

Eckert & Ziegler Medical operates as a platform-plus-modules architecture offering comprehensive products and services for nuclear medicine and radiation therapy. The core Modular-Lab synthesis platform includes three distinct systems: Modular-Lab Standard (research-focused tubing-based system), Modular-Lab PharmTracer (cassette-based routine production system), and Modular-Lab eazy (compact radiometal synthesizer). These are complemented by dedicated software (Modular-Lab Software), quality control products (MiniScanPRO TLC Scanner, AR-2000 TLC Scanner, FlowCountPRO, RaPET Chromatography Software), and consumables (Modular-Lab Cassettes). The radioisotope portfolio includes GalliaPharm (Ge-68/Ga-68 generator), Yttriga (Yttrium-90 chloride), and Lutetium-177, supported by GMP Suites and Contract Manufacturing services. The radiation therapy portfolio includes prostate seed brachytherapy (I-125 seeds), ophthalmic brachytherapy (Ru-106 plaques), and radiotherapy accessories. Engineering capabilities via Isotope Technologies Dresden (ITD) provide hot cells and radiation protection solutions. Services span from radiopharmaceutical development through clinical phases to commercial manufacturing.

Differentiator

Problem solved

Functional benefit

Brands

• GalliaPharm: GMP Gallium-68 Generator for production of Gallium-68 without a cyclotron
• Yttriga
• Modular-Lab
• MiniScanPRO
• AR-2000
• RaPET
• Theralugand

Products and services

• Modular-Lab Standard Tubing-based radiosynthesizer designed for research and development of new radiopharmaceuticals, enabling custom synthesis processes from unit operation modules with GAMP 5 and Part 11 compliance. For pharma companies, biotech, and research institutions developing PET tracers.
• Modular-Lab PharmTracer Cassette-based radiosynthesizer for efficient routine production and research of radiopharmaceuticals without cross-contamination, supporting 18F, 68Ga, 111In, 177Lu, 90Y tracers. For pharma and clinical radiopharmacy customers.
• Modular-Lab eazy Smallest radiosynthesis system on the market for efficient routine production of radiometals, featuring innovative cassette design and pressure-based liquid transfer technology. For clinical and research radiopharmaceutical production of 68Ga and other radiometals.
• GalliaPharm Ge-68/Ga-68 generator for GMP-compliant production of Gallium-68 without a cyclotron. For hospitals, radiopharmacies, and pharma companies producing Ga-68 radiopharmaceuticals for PET imaging.
• Yttriga Sterile Yttrium-90 chloride solution for radiopharmaceutical production. For pharma companies and radiopharmaceutical developers (e.g., SIR-Spheres by Sirtex Medical).
• Medical Radioisotopes Portfolio Wide range of radioisotopes including Gallium-68 generators, Yttrium-90, Lutetium-177, Actinium-225 for research, development, clinical trials and routine applications. GMP and chemical grade.
• Theralugand Carrier-free Lutetium-177 chloride solution for clinical activities. For pharma companies and clinical radiopharmacies.
• MiniScanPRO TLC Scanner GMP-compliant Thin Layer Chromatography scanner for detection of various radioisotopes (68Ga, 18F, 99mTc, 123I, 90Y, 177Lu, 64Cu, 111In) with dual-channel capability. For nuclear medicine QA/QC labs.
• AR-2000 TLC Scanner Industry gold standard radio-TLC imaging scanner for detection of radiolabeled compounds in TLC plates, including PET radiopharmaceuticals and alpha/beta emitters. Linear over 4-5 decades of activity. For nuclear medicine QC labs.
• FlowCountPRO HPLC Remote Detection Unit Standalone HPLC remote detection unit for real-time activity measurement of various radionuclides with touchscreen interface and up to six detectors. Compatible with all chromatography data systems via pulse output up to 500 kHz.
• Modular-Lab Software GMP-compliant programming software for Modular-Lab synthesis systems with graphical drag-and-drop interface, supporting compliance with GMP, cGMP, GAMP 5 and 21 CFR Part 11 regulations. Includes user management with four security levels, automated audit trail, available in editable and non-editable versions.
• RaPET Chromatography Software Chromatography data collection and evaluation software for radio-HPLC and TLC systems with GMP database, 21 CFR Part 11 compliance, batch reporting, and export functions to word processing and spreadsheet applications.
• Modular-Lab Cassettes Disposable, GMP-compliant synthesis cassettes for Modular-Lab systems, customizable according to specifications including filters, cartridges, and reagents. Gamma-sterilized per AAMI TIR33/ISO 11137 with 18-month shelf life and barcode identification.
• Hot Cells and Radiation Protection Solutions Customized hot cell solutions and in-cell equipment for handling radioactive material, provided by Isotope Technologies Dresden (ITD) with shielding for alpha, beta, and gamma emitters. Covers shielding from simple configurations to complex manufacturing or disposal processes. Full project management from design through installation and training.
• Prostate Seed Brachytherapy Products Permanent prostate implants (I-125 seeds) in loose and stranded form for LDR brachytherapy treatment of localized prostate cancer. Supported by patient information services, aftercare passports, and implantation cards.
• Ophthalmic Brachytherapy Products Ruthenium-106 radioactive plaques for treatment of eye tumors including uveal melanomas, retinoblastomas, and conjunctival melanomas.
• Radiotherapy Accessories Gold markers in pre-loaded needles for target visualization during external beam radiation therapy and brachytherapy procedures.
• GMP Suites Licensed radioisotope laboratories for development and manufacturing of batches for clinical trials, equipped with hot cells for alpha, beta, and gamma emitters under GMP conditions.
• Contract Manufacturing (CMO) Services Clinical and commercial supply services for projects using alpha, beta, or gamma radiation, including GLP and cGMP-compliant production infrastructure and regulatory support. Spans from early development through commercial distribution.
• Radiopharmaceutical Development Services Services from pre-clinical development to process design and scale-up with support through all clinical phases and commercial distribution. Develops robust radioconjugates and optimizes manufacturing and testing methods.

Quantifiable outcome

• 500+ synthesis systems and 2,500+ analytical devices deployed worldwide
• +3 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration5 records

Feature10 records

Partnerships

Ten partnerships are on record, tiered core and minor.

• DC PharmacoreStrategic or Co-development Partner · 1 January 2026Eckert & Ziegler and DC Pharma opened a commercial medical isotope production site in Jintan, Changzhou, China in June 2026, expanding production capacity into the Chinese market.
• Ipsen (via Octreopharm Sciences acquisition)coreStrategic or Co-development Partner · 1 January 2015Prior to Ipsen's acquisition of Octreopharm Sciences in 2015, Eckert & Ziegler invested in OPS, provided laboratory space and equipment, and helped expedite development of NET management compounds. Eckert & Ziegler continues cooperation as a contract manufacturer for Ipsen/OPS.
• BayercoreStrategic or Co-development PartnerEckert & Ziegler serves as manufacturing partner for clinical supply of Bayer's innovative Targeted Thorium Conjugates (TTCs) in Europe. TTCs are a next-generation targeted alpha therapy using the alpha-emitter Thorium-227. Eckert & Ziegler provides infrastructure for handling, manufacture, and distribution of TTCs for clinical trials in Europe.
• CurasightcoreStrategic or Co-development PartnerCurasight is a pioneer working on exploitation of the novel PET imaging target uPAR for improved diagnosis of various cancers. Eckert & Ziegler provides qualified personnel, laboratory space, and equipment to get the uPAR PET ligand ready for market, executing experimental work and regulatory preparation.
• Sirtex MedicalcoreStrategic or Co-development PartnerSirtex manufactures SIR-Spheres Y-90 resin microspheres for Selective Internal Radiation Therapy (SIRT) of liver cancer. Eckert & Ziegler is in a long-term supply agreement for Yttrium-90, supplying Sirtex's sites in Frankfurt, Boston, and Singapore as a reliable partner.
• CuriumminorStrategic or Co-development PartnerEckert & Ziegler cooperated with Curium to establish STRIASCAN production by providing a Modular-Lab PharmTracer system based on process and laboratory environment specifications. Developed a special single-use cassette and application design for Modular-Lab Software, provided documentation for qualification and risk analysis, and trained Curium's employees.
• PentixapharmminorStrategic or Co-development PartnerPrior to Eckert & Ziegler acquiring a majority stake, Pentixapharm rented a GMP suite for research work. Eckert & Ziegler then supported development of a fully automated production process for the company's lead investigational product on the Modular-Lab platform, with custom cassettes manufactured in GMP clean rooms.
• Physikalisch-Technische Bundesanstalt (PTB)minorStrategic or Co-development PartnerPTB's project on European standardization of dosimetry for electronic brachytherapy includes scientific evaluation of five intraoperative systems providers, including Eckert & Ziegler. This provides physical measurements and useful information about the company's own system.
• GEC-ESTRO (BRAPHYQS project)minorStrategic or Co-development PartnerThe BRAPHYQS project WP22 on ocular brachytherapy with Ru-106 was advanced with two international surveys analyzing clinical practice in physics and physician use. The project was supported by industry, in particular by Eckert & Ziegler. First results have been published in Radiotherapy and Oncology.
• Victoria Cohen Eye Cancer Charitable Trust (VCECCT)minorGTM or Marketing PartnerThe VCECCT helps aspiring ocular oncologists by awarding scholarships for fellowships worldwide. Eckert & Ziegler is proud to support the VCECCT and its cause, supporting education in ophthalmic brachytherapy.

Scale indicators6 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• GE HealthCare: Diversified medical imaging and radiopharmaceutical incumbent with broad PET tracer portfolio and proprietary stable isotope production. Overlaps with E&Z in nuclear medicine imaging tracers and broader radiopharma manufacturing, but as part of a much wider medtech portfolio.
• Cardinal Health (Nuclear Pharmacy Services): Operates the largest nuclear pharmacy network in the United States, distributing radiopharmaceuticals to hospitals and clinics. Comparable in radiopharma distribution and downstream nuclear medicine supply chain, though as part of a much broader healthcare distributor.
• Bracco Imaging: Global imaging agent manufacturer with a growing radiopharmaceutical portfolio and contract manufacturing capabilities. Comparable in nuclear medicine imaging tracer supply and radiopharma manufacturing, though within a much broader diagnostic imaging business.
• Bayer (Radiology / Targeted Alpha Therapy): Pharma incumbent developing Targeted Thorium Conjugates (TTCs) with E&Z as their manufacturing partner. Comparable in radiopharmaceutical therapeutic development and commercial ambitions, though Bayer operates at a vastly larger scale and across many non-nuclear franchises.

Direct peers

• Nordion: Major supplier of medical isotopes (Mo-99, I-131, Xe-133) and gamma sterilization services. Comparable to E&Z in upstream radioisotope production, distribution, and radiopharmaceutical supply, with similar exposure to reactor-based supply chains.
• Sirtex Medical: Developer and manufacturer of SIR-Spheres Y-90 resin microspheres for liver cancer SIRT, with multi-site manufacturing in Frankfurt, Boston, and Singapore. Direct overlap with E&Z as Y-90 customer; comparable in radioligand therapy manufacturing and commercial radiopharma distribution.
• Curium: One of the largest nuclear medicine companies globally, manufacturing radiopharmaceuticals and operating SPECT/PET radiopharmacies. Direct overlap with E&Z in radiopharma manufacturing, Ga-68 generator supply, and contract manufacturing services — E&Z also serves as a supplier (Modular-Lab PharmTracer for STRIASCAN).
• ITM Isotope Technologies Munich: Emerging European radiopharmaceutical manufacturer specializing in Lu-177 and other therapeutic radionuclides. Comparable to E&Z in radioisotope production, GMP manufacturing, and target customers in theranostics — though more narrowly focused on therapeutic isotopes.
• Lantheus Holdings: Radiopharmaceutical-focused company with commercial diagnostic products (DEFINITY, PYLARIFY) and growing radioligand therapy pipeline. Directly comparable to E&Z Radiopharma in radiopharma manufacturing capabilities and target market of nuclear medicine clinicians.
• Telix Pharmaceuticals: Commercial-stage radiopharmaceutical company developing diagnostic and therapeutic products (Illuccix, etc.) with proprietary manufacturing. Overlaps with E&Z in radiopharma manufacturing capabilities and theranostic targeting.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/@EUZBebig
• LinkedInlinkedin.com/company/eckert-&-ziegler-radiopharma-inc

Compliance8 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Eckert & Ziegler Radiopharma Inc