Institut für Klinische Epidemiologie und Biometrie (IKE-B)

What Institut für Klinische Epidemiologie und Biometrie (IKE-B) does

IKE-B is a university research institute within the Medical Faculty of Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany. Founded in 2011 and operating as a state-affiliated public entity with 1-10 employees, the institute focuses on clinical epidemiology and biometry — the design, statistical evaluation, and methodological analysis of healthcare studies. Its most visible program is its role as the central epidemiological evaluator of the nationwide HI-PLUS study, which examines heart failure care delivery across Germany. In that capacity, IKE-B coordinated 55 cardiology practices, trained 70 medical assistants, and oversaw enrollment of 712 patients, working in close partnership with the Deutsches Zentrum für Herzinsuffizienz (DZHI) Würzburg.

IKE-B does not operate a commercial product, platform, or service. Its outputs are study evaluations, methodological contributions, and academic knowledge rather than sellable goods. The business model, to the extent one exists, is publicly funded academic research: budgets flow from JMU and research-grant channels, and the institute's "customers" are its academic and clinical partners rather than paying buyers. There is no pricing model, no go-to-market motion, and no disclosed revenue. The institute's value lies in its ability to bring rigorous biostatistical and epidemiological expertise to multi-site clinical evaluations, particularly within the German academic cardiology ecosystem anchored by DZHI.

For a PE/VC/M&A audience, IKE-B is effectively non-investable: it is a non-commercial, publicly funded research unit with no revenue base, no product, and no plausible commercialization pathway surfaced in the available data. The relevant strategic question is not growth equity or M&A positioning, but rather the institute's role within Würzburg's broader academic cardiology cluster and its capacity to retain grant funding and methodological relevance against better-resourced competitors.

Name

Institut für Klinische Epidemiologie und Biometrie (IKE-B)

Legal name

Institut für Klinische Epidemiologie und Biometrie (IKE-B)

Website

https://med.uni-wuerzburg.de

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

1–10 employees

Short description

IKE-B is a publicly funded university research institute at Julius-Maximilians-Universität Würzburg that provides clinical epidemiology and biostatistical evaluation of healthcare studies, notably the nationwide HI-PLUS heart failure study, serving academic and clinical partners rather than paying customers.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (54171)

SIC

Services-Health Services (8000)

akta.pro industry

PRIMARYHLACAOAM

Real-World Data (RWD) / Real-World Evidence (RWE) & Observational Research Platforms

Healthcare & Life Sciences/Digital Health & Health IT/Clinical Trials & Research Informatics (eCOA/ePRO/EDC)

SECONDARYBPAIAJAM

Health Data, Vital Statistics & Population Health Informatics

Business & Public Services/Public Sector & Government Administration/Public Health Administration & Regulation

Keywords

• Clinical epidemiology
• Biostatistical analysis
• Health services research
• Clinical study evaluation
• Epidemiological study design

Headquarters

HQ city

Würzburg, Bavaria

HQ country

Germany

HQ region

Europe

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D

Core offering

IKE-B is a university research institute that conducts epidemiological evaluation of large-scale healthcare delivery studies and provides biostatistical analysis and clinical research methodology. Its primary work is designing and executing cluster-randomized evaluations of integrated care models — most notably the HI-PLUS nationwide heart failure study — and generating peer-reviewed evidence for the German healthcare system.

Product overview

The Institut für Klinische Epidemiologie und Biometrie (IKE-B) is a clinical research institute at the University of Würzburg. It provides epidemiological research services, particularly in clinical study evaluation and data analysis. The institute conducts healthcare research including clinical studies, health services research, and epidemiological analyses. It is not a product company but rather an academic research unit focused on evaluating healthcare interventions and clinical research outcomes.

Differentiator

Problem solved

Functional benefit

Products and services

• HI-PLUS Study Evaluation Services Epidemiological and biostatistical evaluation services for the HI-PLUS nationwide healthcare study, assessing whether structured case management with telemonitoring coordinated by trained medical assistants in cardiology practices improves quality of life and reduces hospitalizations for heart failure patients. Delivered for DZHI Würzburg.

Quantifiable outcome

• 712 patients enrolled in the HI-PLUS study over three years; 585 completed 12-month follow-up; 55 cardiology practices recruited; 48 actively participating; 70 medical assistants trained across 7 courses; study published in Clinical Research in Cardiology (2026)

Segments2 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Two partnerships are on record, tiered core and minor.

• Deutsches Zentrum für Herzinsuffizienz (DZHI) WürzburgcoreStrategic or Co-development PartnerIKE-B conducts the evaluation of the HI-PLUS nationwide healthcare study led by DZHI Würzburg. The study investigates whether structured case management with telemonitoring, coordinated by specially trained medical assistants in cardiology practices, can improve quality of life for heart failure patients. IKE-B evaluates the study outcomes, data, and results. This is a core research collaboration within the German healthcare system.
• Academic Teaching Hospitals (Lehrkrankenhäuser) of the Medical Faculty of WürzburgminorOthersThe Medical Faculty of Würzburg maintains a network of affiliated teaching hospitals (Lehrkrankenhäuser) across the region, including University Hospital Würzburg, Klinikum Würzburg Mitte, Leopoldina Krankenhaus Schweinfurt, Klinikum Main-Spessart, Main-Klinik Ochsenfurt, Klinik Rothenburg, and others. These hospitals support practical year (PJ) training for medical students and may serve as clinical research sites.

Recent moves3 records

Expansion highlights2 records

Direct peers

• Institut für Medizinische Biometrie, Epidemiologie und Informatik (IMBEI), Universitätsmedizin Mainz: University institute combining biometry, epidemiology, and medical informatics for clinical and population health research. Comparable in disciplinary scope and academic integration within a German university medical center.
• Kompetenznetz Herzinsuffizienz (KNHI): German nationwide research network dedicated to heart failure, coordinating multicenter studies and translational research. Highly comparable because IKE-B evaluates the HI-PLUS heart failure study within the same disease area and collaborates with overlapping cardiology practice networks.
• Institut für Medizinische Biometrie und Statistik (IMBS), Universität zu Lübeck: University institute focused on medical biometry and statistics with active clinical trial methodology and epidemiological research. Comparable in function (biometric/epidemiological support for clinical studies) and academic operating model.
• Institut für Klinische Epidemiologie und angewandte Biometrie (IKEAB), Universität Tübingen: University institute at a German medical faculty with a nearly identical name and remit — clinical epidemiology and applied biometry, with active health services and methodological research. Directly comparable in scope, organizational setting, and customer base (German public healthcare research).
• Institut für Klinische Epidemiologie, Martin-Luther-Universität Halle-Wittenberg: A clinical epidemiology institute at a German university medical faculty, sharing the same narrow disciplinary focus and academic operating model as IKE-B. Directly comparable in research scope, funding model, and integration with regional healthcare research networks.
• Zentrum für Evidenzbasierte Gesundheitsversorgung (ZEGV), Universitätsklinikum Carl Gustav Carus Dresden: University hospital center conducting health services research, epidemiological studies, and evaluation of integrated care models in the German healthcare system. Comparable in disease-management evaluation focus and integration with regional physician networks.

Broad incumbents

• Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG): Federal German institute for health technology assessment and evidence-based healthcare evaluation. Comparable as a producer of rigorous evidence informing German healthcare policy, though operating at a much larger national scale than IKE-B.
• Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK): National German research center for cardiovascular disease, encompassing a much broader portfolio of basic, translational, and clinical cardiovascular research than IKE-B. Comparable as an ecosystem player in German cardiovascular research and a likely coordinator/funder of large multicenter studies.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights5 records

Customer concentration

• LinkedInlinkedin.com/company/ike-b

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Institut für Klinische Epidemiologie und Biometrie (IKE-B)