Center for Health Outcomes and Interdisciplinary Research (CHOIR) at Massachusetts General Hospital

What Center for Health Outcomes and Interdisciplinary Research (CHOIR) at Massachusetts General Hospital does

The Center for Health Outcomes and Interdisciplinary Research (CHOIR) is a non-profit academic clinical research center housed at Massachusetts General Hospital within the Mass General Brigham healthcare system. Founded in 2018 by Dr. Ana-Maria Vranceanu (originally as the Integrated Brain Health Clinical and Research Program, rebranded as CHOIR in 2024), the center develops and tests technology-enhanced mind-body and lifestyle interventions targeting patients with chronic pain, neurological illness (stroke, traumatic brain injury, dementia, multiple sclerosis, ALS), age-related cognitive decline, and their family caregivers. Interventions are delivered via live video platforms, smartphone applications, web-based platforms, and virtual reality, with mechanistic outcomes measured through an in-house Psychophysiological Core equipped with NIRSport functional near-infrared spectroscopy (fNIRS) and Quantitative Sensory Testing. Research methodology follows the NIH Stage Model of intervention development and the Science of Behavior Change framework, employing user-centered design, mixed methods, and community-engaged research principles.

CHOIR operates across five integrated domains — Research, Training, Community, Physiology, and Clinical — anchored by the MassGeneral Brigham BRIDGE Core (launched 2024), which provides consultations to clinician scientists institution-wide. The center runs a portfolio of fully powered efficacy and comparative effectiveness randomized clinical trials (Recovering Together, Active Brains, Resilient Together-YOD, iHOPE/GetActive+, My Healthy Brain, HABIT, BRISK) and operates the MGH Caregiver Clinic, an outpatient service for care partners of patients with neurodegenerative conditions. A robust training ecosystem includes the Lifespan Health Predoctoral Internship, Clinical-Research Practicum, K Club mentoring program (16 junior investigators), Bridge-the-Gap T32 Postdoctoral Fellowship, Mass-ENVISION RCMAR, CONFIDE-ADRD Roybal Center, and a Dementia Palliative Care Clinical Trials R25 program.

Revenue is grant-based rather than commercial. CHOIR is funded primarily through National Institutes of Health grants (NIA, NINR, NCCIH, NIGMS, NICHD, NIDCR), PCORI comparative effectiveness awards, Department of Defense research funding, and foundation grants (Robert Wood Johnson, ALS Association, National Palliative Care Research Center). As a non-profit research center within Mass General Brigham, CHOIR has no equity investors, sells no products, and reports no revenue figures publicly. Distribution occurs through clinical trials at MGH and partner sites (Duke University, Rush University, MGH Revere community clinics, Black Ministerial Alliance churches, Massachusetts Councils on Aging senior centers), with digital delivery extending reach to research participants regionally across the Northeast United States.

Name

Center for Health Outcomes and Interdisciplinary Research (CHOIR) at Massachusetts General Hospital

Legal name

Center for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital

Website

https://mghchoir.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

11–50 employees

Short description

The Center for Health Outcomes and Interdisciplinary Research (CHOIR) is a non-profit clinical research center at Massachusetts General Hospital that develops, tests, and delivers technology-enhanced mind-body and lifestyle interventions for patients with chronic pain, neurological illness, and age-related cognitive decline, along with their family caregivers, while training the next generation of clinical investigators.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Offices of Mental Health Practitioners (except Physicians) (621330), Offices of Physicians, Mental Health Specialists (621112), Other Individual and Family Services (624190)

SIC

Services-Health Services (8000), Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Home Health Care Services (8082)

akta.pro industry

PRIMARYHLAFACAA

Outpatient Mental Health Clinics & Counseling Centers

Healthcare & Life Sciences/Healthcare Providers & Systems/Behavioral Health & Substance Use Treatment

SECONDARYHSABAEAH

Cognitive Stimulation & Reminiscence Therapy (Non-Clinical)

Home & Personal Services/Elder Care & In-Home Care Services/Dementia & Alzheimer’s In-Home Care

SECONDARYHSADAJAB

Mindfulness-Based Coaching & Training (MBSR/MBCT-style)

Home & Personal Services/Fitness, Wellness & Personal Training/Meditation, Mindfulness & Breathwork

Keywords

• Clinical research programs
• Mind-body interventions
• Behavioral health research
• Caregiver support services
• Clinical psychology training

Headquarters

HQ city

Boston

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Others

Revenue model

1. NIH Research Grants: Major funding from National Institutes of Health including NIA, NINR, NCCIH, NIGMS, NICHD, NIDCR for clinical trials and intervention development research.
2. PCORI Awards: Patient-Centered Outcomes Research Institute funding for comparative effectiveness trials.
3. Department of Defense Grants: DoD funding for research including orthopedics, neurofibromatosis, and military health research.
4. Foundation Grants: Funding from foundations including Robert Wood Johnson Foundation, ALS Association, National Palliative Care Research Center, and others.

Distribution channels4 records

Marketing channels4 records

Core offering

CHOIR is a non-profit clinical research center at Massachusetts General Hospital that develops, tests, and implements technology-enhanced mind-body and lifestyle behavioral interventions (e.g., Active Brains, Recovering Together, Resilient Together, HABIT) for patients with chronic pain, neurological illness, and dementia, as well as their caregivers and dyads. It also operates an outpatient clinical caregiver clinic and a portfolio of clinical research training programs (predoctoral internship, postdoctoral fellowships, K Club mentoring, R25/R32/T32 training grants).

Product overview

CHOIR (Center for Health Outcomes and Interdisciplinary Research) is a clinical research center at Massachusetts General Hospital that offers a portfolio of research programs, clinical services, and training opportunities. The core research programs include Active Brains, Recovering Together, Resilient Together, iHOPE/GetActive+, My Healthy Brain, and HABIT - all mind-body and behavioral interventions targeting patients, caregivers, and dyads across the health-illness continuum. The center operates the BRIDGE Core infrastructure providing consultations across Research, Training, Community, Physiology, and Clinical domains. CHOIR provides the MGH Caregiver Clinic for outpatient psychological services. The training ecosystem includes Mass-ENVISION RCMAR, Bridge-the-Gap T32 Fellowship, CONFIDE-ADRD Roybal Center, Dementia PCCT R25 Program, K Club mentoring program, Lifespan Health Predoctoral Internship, and Clinical-Research Practicum. CHOIR also hosts the Pain Working Group and Psychophysiological Domain for mechanistic research.

Differentiator

Problem solved

Functional benefit

Products and services

• Active Brains
• Recovering Together
• Resilient Together: Young Onset Dementia (RT-YOD)
• iHOPE / GetActive+
• My Healthy Brain
• HABIT (Healthy Aging as Black Adults: In It Together)
• BRISK (Building Resilience in Skilled Nursing Care)
• MGH Caregiver Clinic
• BRIDGE Core (Biobehavioral Research: Intervention Design, Guidance, and Execution)
• Mass-ENVISION RCMAR (Research and Education Component)
• Bridge-the-Gap T32 Postdoctoral Fellowship
• CONFIDE-ADRD Roybal Center
• Dementia Palliative Care Clinical Trials Training Program R25
• K Club
• Lifespan Health Predoctoral Internship
• Clinical-Research Practicum

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• Duke UniversitycoreStrategic or Co-development Partner · 5 June 2024Multi-site collaboration on R01 grant from NCCIH for mind-body and activity program for chronic pain, alongside MGH and Rush University.
• Black Ministerial Alliance of Greater BostoncoreStrategic or Co-development PartnerCommunity partnership for delivering Healthy Activity Improves Lives (HAIL) study through predominantly Black churches in Greater Boston, adapting Fit and Strong! program for older Black adults.
• MGH Revere Community ClinicscoreStrategic or Co-development PartnerImplementation partner for GetActive+ program serving underserved English and Spanish-speaking older adults with chronic musculoskeletal pain.
• Rush UniversitycoreStrategic or Co-development PartnerMulti-site collaboration on NCCIH R01 grant for mind-body and activity program for chronic pain, alongside MGH and Duke University.
• Spaulding Rehabilitation HospitalminorStrategic or Co-development PartnerClinical training site for geropsychology rotations and research collaboration for stroke inpatient services.
• Mass Eye and EarminorStrategic or Co-development PartnerClinical collaboration for embedded psychologist services and research on ophthalmology-related conditions.
• Massachusetts Councils on AgingminorStrategic or Co-development PartnerPartner for 'Prevention Starts Here' study piloting My Healthy Brain program through senior centers in Massachusetts.

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Center for Mind-Body Medicine: Nonprofit organization that develops and disseminates mind-body medicine interventions, trains healthcare professionals and conducts community-based research. Comparable mission around evidence-based mind-body interventions and training of clinician scientists.
• Family Caregiver Alliance: National nonprofit operating the National Center on Caregiving, providing caregiver services, policy research and intervention development. Comparable caregiver-focused research, training and service-delivery mission to CHOIR's dyadic and caregiver clinic work.
• UCSF Memory and Aging Center: UCSF center running NIH-funded research on dementia, mild cognitive impairment and caregiver dyadic interventions. Highly comparable research portfolio, particularly to CHOIR's Resilient Together-YOD, Active Brains and CONFIDE-ADRD programs.
• Osher Center for Integrative Health at UCSF: UCSF-based integrative medicine research center running NIH-funded trials of mind-body and lifestyle interventions, training clinicians and partnering with UCSF Memory and Aging Center on caregiver research. Closely comparable academic medical center model.
• Osher Center for Integrative Health at Harvard Medical School and Brigham and Women's Hospital: Harvard-affiliated integrative medicine center conducting clinical research on mind-body and lifestyle interventions for chronic pain, aging and caregiver populations. Directly comparable research portfolio, training pipeline and Harvard Medical School affiliation.
• Benson-Henry Institute for Mind Body Medicine at Massachusetts General Hospital: Co-located at Massachusetts General Hospital and focused on mind-body interventions for stress, chronic illness and behavior change. Most directly comparable to CHOIR given shared institution, similar intervention philosophy and overlapping clinical/research footprint.
• Osher Center for Integrative Health at Northwestern: Northwestern-affiliated Osher Center conducting clinical research on integrative therapies, pain and lifestyle interventions for chronic conditions. Directly comparable academic medical center integrative medicine research and training operation.

Broad incumbents

• Alzheimer's Association: Large national nonprofit funding dementia research, caregiver programs and policy advocacy. Comparable focus on dementia caregiver populations and research funding, but operates as a national funder and advocacy organization rather than a clinical trials center.
• Massachusetts General Hospital Department of Psychiatry: Same-institution behavioral health clinical and research operation providing outpatient mental health services and conducting intervention research. Comparable clinical psychology training and behavioral intervention research, though broader in scope than CHOIR's mind-body focus.

Emerging players

• RAND Center for Caregiver Excellence: RAND research initiative focused on caregiver research, intervention evaluation and policy. Comparable research mission around caregiver outcomes and intervention development though broader policy and evaluation lens rather than clinical trials.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/mghchoir

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Center for Health Outcomes and Interdisciplinary Research (CHOIR) at Massachusetts General Hospital