Say YES to HOPE

What Say YES to HOPE does

Say YES to HOPE is a U.S. nonprofit organization founded in 2007 and headquartered in Canton, Texas, that provides support and educational services to patients diagnosed with advanced or metastatic cancer. The organization runs a national toll-free survivor line (1-877-937-7478) and a comprehensive content portal covering 15 cancer types (bladder, brain, breast, cervical, colorectal, esophageal, GIST, liver, lung, melanoma, neuroendocrine, ovarian, pancreatic, prostate, renal cell) and how each may metastasize to six secondary sites (bones, brain, liver, lungs, peritoneum, skin). Core services include peer matching to long-term survivors, survivor bag fulfillment, a Find Assistance referral service, insurance appeals support, and multidisciplinary treatment information spanning medical, surgical, and radiation oncology plus interventional radiology.

The operating model is donation-funded and free to patients. Revenue is generated exclusively through charitable contributions solicited via the website's prominent donate button; there is no disclosed pricing, contract, or fee-for-service component, and the organization is described as private/non-profit with no parent company, venture backing, or public listing. The technology stack is a content/SEO-driven WordPress-style website (asset URLs under sayyestohope.org/wp-content/uploads) with no mobile app, no public API, and no SDK — the platform's value lies in editorial depth and curated referral pathways rather than software capabilities.

The organization embeds into the patient-decision content for three named medical-device manufacturers — Sirtex Medical (SIR-Spheres), Boston Scientific (Therasphere), and GT Medical Technologies (GammaTile) — and maintains a national referral directory of interventional radiology treatment centers that administer SIRT (Yttrium-90) therapy. Staffing is small (approximately 5 employees), with no management team or executive roster disclosed in the available inputs, suggesting a lean operations structure supported by volunteers and partner organizations.

Name

Say YES to HOPE

Legal name

Say YES to HOPE

Website

https://sayyestohope.org

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Short description

Say YES to HOPE is a Canton, Texas-based nonprofit (founded 2007, ~5 employees) that provides free education, peer support, and referral services to U.S. patients with advanced or metastatic cancer via a toll-free survivor line and a content portal covering 15 cancer types and six metastatic sites.

Ownership category

akta.pro rank

Product category

Cancer Patient Support Services (Nonprofit)

NAICS

Voluntary Health Organizations (813212), Other Individual and Family Services (624190)

SIC

Services-Health Services (8000), Services-Social Services (8300)

akta.pro industry

PRIMARYBPAGACAA

Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS)

Business & Public Services/Nonprofit, NGO & Social Services/Health & Medical Nonprofits

SECONDARYBPAGACAK

Palliative Care, Hospice & Serious Illness Support

Business & Public Services/Nonprofit, NGO & Social Services/Health & Medical Nonprofits

Keywords

• Metastatic cancer support
• Cancer patient education
• Survivor peer matching
• Insurance appeals assistance
• Nonprofit cancer helpline

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Supply Chain, Others

Revenue model

1. Donations: The organization operates as a nonprofit and relies on charitable donations from individuals and organizations. The website prominently features a donate button.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels3 records

Core offering

Say YES to HOPE is a nonprofit that provides free education, peer support, and practical assistance to patients with advanced or metastatic cancer and their caregivers. Its core offerings include a structured educational resource on 15 cancer types and 6 metastatic sites, a toll-free survivor helpline, survivor-to-patient peer matching, survivor bags, insurance appeals guidance, and personalized find-assistance referrals. All services are delivered at no cost to the patient and funded through charitable donations.

Product overview

Say YES to HOPE is a nonprofit organization providing advanced cancer support and information to patients with metastatic cancer that has spread. The organization operates a toll-free survivor line (1-877-937-7478) and offers a comprehensive digital resource hub featuring detailed information on 15 cancer types and how cancers spread to different body parts (bones, brain, liver, lungs, peritoneum, skin). Services include survivor support with peer connections and survivor bags, personalized assistance finding, and insurance appeals help. The organization also provides extensive educational materials on multidisciplinary treatment approaches including medical oncology, surgical oncology, radiation oncology, and interventional radiology options.

Differentiator

Problem solved

Functional benefit

Products and services

• Cancer Type Information Hub Detailed educational resource on 15 metastatic cancer types for cancer patients and their families, providing information on each cancer type and the available multidisciplinary treatment options.
• Cancer Metastasis Information Educational resources explaining how cancer spreads to specific body parts (bones, brain, liver, lungs, peritoneum, skin), with information on symptoms, tests, and treatment approaches, for metastatic cancer patients and their families.
• Toll-Free Survivor Line A helpline (1-877-937-7478) providing personalized assistance, survivor bags, peer connections, and support for cancer patients and their families at no cost.
• Survivor Support Program Program offering survivor bags, peer matching with others who have experienced similar cancers, and connections to survivors for emotional support for patients with metastatic cancer.
• Find Assistance Service Personalized assistance service connecting metastatic cancer patients with resources and support tailored to their specific needs.
• Insurance Appeals Assistance Help and guidance for cancer patients navigating insurance appeal processes and coverage challenges, provided at no cost.
• Multidisciplinary Treatment Information Detailed information on multidisciplinary treatment options including medical oncology, surgical oncology, radiation oncology, and interventional radiology approaches for various cancer metastases.

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature1 record

Partnerships

Four partnerships are on record, tiered core.

• Sirtex Medical (SIR-Spheres)coreStrategic or Co-development PartnerSIRT (Selective Internal Radiation Therapy) is highlighted as a key treatment option. The organization provides extensive information about Yttrium 90 microspheres (SIR-Spheres) from Sirtex Medical, including detailed pre-treatment, treatment day, and post-treatment guidance. Patients are referred to Sirtex for more information at 1-888-474-7839 or www.sirtex.com.
• Boston Scientific (Therasphere)coreStrategic or Co-development PartnerThe organization provides detailed information about Therasphere (Yttrium 90 microspheres) from Boston Scientific as another treatment option for liver tumors. Patients are referred to Boston Scientific at 1-888-272-1001 or www.therasphere.com.
• GT Medical Technologies (GammaTile)coreStrategic or Co-development PartnerGammaTile Therapy is featured as a Surgically Targeted Radiation Therapy (STaRT) option for operable brain tumors. GT Medical Technologies provides radiation sources embedded in collagen tiles for immediate post-surgical radiation treatment.
• Treatment Centers (SIRT Facilities)coreChannel Partner/ Reseller/ DistributorThe organization maintains a list of treatment centers near patients for SIRT (Yttrium 90) therapy. These are interventional radiology centers specially trained to administer the microspheres treatment. Patients are referred for evaluation and treatment at these facilities.

Scale indicators2 records

Recent moves5 records

Expansion highlights4 records

Broad incumbents

• Susan G. Komen: Disease-specific (breast cancer) nonprofit with research, community health, and patient support programs. Comparable disease-specific focus model, but operates at massive scale with established brand.
• American Cancer Society: Largest U.S. cancer nonprofit offering research funding, patient support, and education across all cancer types. Dominant incumbent that competes for donor dollars and patient mindshare; overlaps in education and support but at vastly larger scale.

Direct peers

• Imerman Angels: Nonprofit providing one-on-one peer mentor matching for cancer patients and caregivers. Most direct overlap with Say YES to HOPE's peer connection program; similarly small-team operated with national reach.
• Livestrong Foundation: Long-established cancer survivorship nonprofit providing navigation, education, and survivor support services. Comparable in survivor-support mission; operates at much larger scale and brand recognition.
• Cancer Support Community: National nonprofit providing psychosocial support, education, and community for cancer patients of all types and stages. Most direct comparable to Say YES to HOPE in mission and service model, though broader in scope across cancer types and stages.
• CancerCare: National nonprofit offering free, professional support services including counseling, support groups, educational workshops, and financial assistance for cancer patients. Comparable to Say YES to HOPE's combined education-plus-practical-support model.
• Pancreatic Cancer Action Network (PanCAN): Disease-specific cancer nonprofit offering patient services, research funding, and advocacy for pancreatic cancer patients. Comparable disease-specific model with strong patient services focus similar to Say YES to HOPE's pancreatic cancer content.

Emerging players

• Triage Cancer: Nonprofit providing cancer-related insurance, financial, and legal navigation resources to patients and caregivers. Directly comparable to Say YES to HOPE's insurance appeals assistance offering, though narrower in scope.
• Stupid Cancer: Nonprofit focused on young adult cancer (ages 15-39), offering peer support, education, and community programs. Comparable community-driven model, but narrower demographic focus than Say YES to HOPE.
• Bone Marrow & Cancer Foundation: Smaller nonprofit providing financial assistance, support programs, and educational resources for cancer patients undergoing bone marrow/stem cell transplants. Comparable in small-team, support-focused operating model.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/say-yes-to-hope

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Say YES to HOPE