日本製薬工業（株）

What 日本製薬工業（株） does

日本製薬工業株式会社 (Nihon Seiyaku Kogyo Co., Ltd.) is a privately held Japanese pharmaceutical manufacturer founded in 1947 in Nagoya and headquartered in Komaki City, Aichi Prefecture. The company specializes in traditional Chinese-medicine-style formulations known in Japan as Kampo, producing over-the-counter drugs for cardiovascular indications (牛黄清心元 series, on the market since 1969), nutritional tonics (オキソピンZ, キングホルンZ, 天好), cold remedies (十神湯分包顆粒, マイヘルスゴールド顆粒), and gastrointestinal products, alongside a parallel health-food line spanning functional display foods (爽潤), nutritional supplements (健歩人潤プレミアム, 田七丹), nutritional functional foods (カンリゲンボン), and designated quasi-drugs.

Manufacturing is anchored at the Komaki GMP-compliant factory (new head office and GMP plant completed April 2000), which since October 2023 also produces the flagship 牛黄清心元 entirely in-house. A second factory in Kitami City, Hokkaido (operational since September 2014) processes locally contract-grown Tokoro pink garlic into aged black garlic (熟成黒にんにく) and spray-dried powders. Inputs include rare animal-based crude drugs (bezoar, musk, antelope horn, borneol) combined with 25 plant-based natural materials, plus an in-house 60-meter-deep pure water system. Quality control relies on liquid chromatography, atomic absorption spectrometry, and bacterial culture testing under pharmaceutical GMP standards.

The business model is wholesale-driven, going to market through a captive nationwide retail channel of approximately 710 member pharmacies and drugstores under 全国連合清心会 (Zenren Rengo Seishinkai), which provides in-store Kampo consultation to end consumers. Wholesale distribution is handled by group subsidiary 日本製薬商事 and external partners including 大正製薬, 天野商事, and 奥田製薬. Direct-to-consumer sales are conducted via the company's own e-commerce shop (launched 2022) and Amazon marketplace listings for non-pharmaceutical SKUs. The company is a subsidiary of the NHC Group (株式会社NHC) and operated with 61 employees as of November 2020, reporting no public revenue figures.

Name

日本製薬工業（株）

Legal name

日本製薬工業株式会社

Website

https://sg-nsk.co.jp

Company type

Private

Founded year

1947

Operating status

Operating

Headcount range

1–10 employees

Short description

日本製薬工業株式会社 is a Japanese Kampo pharmaceutical manufacturer (founded 1947) producing OTC cardiovascular, cold and gastrointestinal drugs, plus health foods and supplements, distributed primarily through a nationwide network of approximately 710 specialized Seishinkai pharmacies and direct e-commerce channels.

Ownership category

akta.pro rank

Product category

OTC Pharmaceuticals (Kampō Medicine)

NAICS

Pharmaceutical Preparation Manufacturing (325412), Medicinal and Botanical Manufacturing (325411)

SIC

Pharmaceutical Preparations (2834), Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

OTC Medicines & Consumer Health Products Distribution (CRAOAHAB)

akta.pro secondary industry

Cold, Flu, Cough & Allergy Remedies (Decongestants, Antihistamines, Cough Syrups, Lozenges) (CRADAMAD)

Keywords

• Kampō pharmaceuticals
• OTC herbal medicine
• Natural health supplements
• Traditional Chinese medicine
• Functional food products

Headquarters

HQ city

小牧市

HQ country

Japan

HQ region

Asia

Offices2 records

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. OTC Pharmaceutical Sales: Sales of regulated over-the-counter (General Use) pharmaceuticals including cardiovascular drugs (牛黄清心元 series), nutritional tonics (オキソピンZ, 天好, キングホルンZ), cold remedies (十神湯分包顆粒, マイフーロンゴールド錠), and gastrointestinal drugs. Distributed through nationwide pharmacy network.
2. Health Food and Supplement Sales: Sales of functional foods, nutritional supplements, nutritional function foods, designated quasi-drugs, and other food products. Includes products like 爽潤 (functional display food), 健歩人潤プレミアム, 熟成黒にんにく, ジンカンカDRINK, and others. Distributed through pharmacy network, e-commerce, and Amazon marketplace.
3. Healthcare Product Sales: General sales of healthcare and wellness products alongside pharmaceutical offerings.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels4 records

Core offering

日本製薬工業 manufactures and sells Kampō (traditional Chinese/Japanese herbal) OTC pharmaceuticals and health foods/supplements at two Japan-based facilities. Its flagship cardiovascular drug 牛黄清心元 is produced in-house at the GMP-certified Komaki factory (since October 2023), while the Kitami (Hokkaido) factory produces aged black garlic and related food products from contract-cultivated GI-certified Tokoro pink garlic. Products are distributed through approximately 710 member pharmacies and drugstores nationwide (全国連合清心会), the company's own online shop, and Amazon Japan.

Differentiator

Problem solved

Functional benefit

Products and services

• 牛黄清心元 (Gōō Seishin Gen) — Cardiovascular OTC Flagship Kampō cardiovascular OTC drug combining 25 types of natural materials including rare animal-based crude drugs. Used for relief of hypertension-related symptoms such as palpitations, numbness, stiff shoulders, dizziness, tinnitus, and head heaviness. Available through pharmacy network as a Category 2 OTC drug.
• 牛黄清心元 日薬金丹 (Gōō Seishin Gen Nicheiyaku Kintan) — Renewed Cardiovascular OTC Renewed version of the flagship 牛黄清心元 cardiovascular Kampō drug, with individual 4-pill packaging for portability and domestic Japanese GMP manufacturing at the Komaki factory. Replaces prior Korean-manufactured version.
• オキソピンZ (Oxisopin Z) Category 3 OTC nutritional tonic for fatigue recovery, appetite loss, and malnutrition. Combines Japanese garlic extract, ginseng, angelica, antler, bezoar, and vitamins B1 and B6.
• 天好 (Tenkō) Kampō nutritional tonic for nourishment and fatigue recovery.
• キングホーレンZ (King Holen Z) Category 2 OTC nutritional tonic drink combining seven herbal ingredients (polygonatum, ginseng, epimedium, mountain cornus, bezoar, antler, mamushi) with taurine and B vitamins. Targets fatigue and nutritional deficiency.
• 蘇源 (Sogen) — Cold Remedy Category 2 OTC cold remedy based on a traditional Chinese formula (和剤 pharmacopeia). Treats common cold symptoms.
• マイフロゴールド錠 (My Flow Gold) — Cold Remedy Cold remedy tablets for relief of common cold symptoms.
• 十神湯分包顆粒 (Jūshin-tō Packet Granules) — Cold Remedy Kampō granule cold remedy based on the traditional 十神湯 formulation for common cold symptoms.
• 爽潤 (Sōjun) — Joint Health Functional Food Functional food supplement for knee joint health. Contains non-denatured type II collagen, N-acetylglucosamine, ceramide, collagen tripeptide, proteoglycan, and mountain ginseng extracts. Sold via pharmacy network and e-commerce.
• 健康人潤プレミアム (Kenkōjin Jun Premium) Grain-type nutritional supplement for joint health support. Combines non-denatured type II collagen, non-denatured proteoglycan, N-acetylglucosamine, chondroitin, and hyaluronic acid.
• ジンカンカDRINK (Jinkanka Drink) Premium Japanese-Chinese herbal health beverage containing 20,000mg of Kanka (desert ginseng) per bottle, blended with Gyokusen Rokuso herbal decoction, trover root, Korean ginseng, and ginkgo leaf. Targeted at health and beauty purposes.
• 熟成黒にんにく (Jukusei Kuro Ninniku / Aged Black Garlic) Aged black garlic produced at the Hokkaido Kitami factory using contract-cultivated GI-certified Tokoro pink garlic. Controlled aging/fermentation produces odorless, sweet-sour black garlic. Certified as an Okhotsk Brand product (2019). Sold via pharmacy network, e-commerce, and Amazon.
• にんにくオリーブオイル (Ninniku Olive Oil) Garlic-infused olive oil made with Hokkaido Tokoro pink garlic from the Kitami factory. Available in multiple package sizes via Amazon Japan.
• 田七丹 (Denchitanchi) Nutritional supplement with Taxus species extract (Yunnan origin) as the main ingredient, in portable grain-type format.
• ロンターゼスリムファイバー (Lontase Slim Fiber) Gastrointestinal drug for chronic constipation that combines dietary fiber with plant-based crude drugs for gentle natural relief.
• カンリゲンボン (Kanri Gen Bon) Peach-flavored nutritional functional food for efficient calcium supplementation with vitamin D support.
• カンリゲンS Bio (Kanri Gen S Bio) Nutritional functional food combining calcium, magnesium, zinc minerals with dandelion, coix seed, angelica keiskei, two types of lactic acid bacteria, and vitamin D3.
• NSK レスveratrol (NSK Resveratrol) Nutritional supplement featuring resveratrol as the key functional ingredient.

Quantifiable outcome

• 710 pharmacies and drugstores nationwide in the Seishinkai network providing in-store Kampō consultation
• +1 more outcomes

Named customers1 record

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• 日本製薬商事株式会社coreChannel Partner/ Reseller/ Distributor · 10 June 1957Group subsidiary established February 2012, serving as the company's primary sales and distribution subsidiary. Handles wholesale distribution of pharmaceutical and health food products across the nationwide network of pharmacy members.
• 株式会社NHCcoreOthers · 10 June 1957Parent/group company. 日本製薬工業 is part of the NHC Group which includes 株式会社日本自然発酵, 株式会社日本自然発酵知多, 株式会社名駅都市開発, and 株式会社南国発酵. NHC Group manages and oversees group companies.
• JAところ（常呂町農業協同組合）coreOthersPartnership with Tokoro Agricultural Cooperative for contract cultivation of Hokkaido pink garlic. JA Tokoro and the Tokoro Garlic Growers Association supply the pink garlic used in aged black garlic, garlic olive oil, and other products. The company has been expanding production annually through this partnership.
• 韓国新薬 (Korea New Drug Co., Ltd.)minorStrategic or Co-development PartnerPrior manufacturing partner for 妙泉牛黄清心元. Established May 2004. Korea New Drug held both Korean pharmaceutical GMP and Japanese pharmaceutical GMP certifications. Manufacturing partnership ended in 2023 with transition to fully domestic in-house production at the Komaki factory.
• 大正製薬株式会社minorChannel Partner/ Reseller/ DistributorMajor Japanese pharmaceutical company listed as a main client/distribution partner in the company's official company profile.
• 天野商事株式会社minorChannel Partner/ Reseller/ DistributorTrading company listed as a main client/distribution partner.
• 奥田製薬株式会社minorChannel Partner/ Reseller/ DistributorPharmaceutical company listed as a main client/distribution partner.

Scale indicators4 records

Recent moves8 records

Expansion highlights5 records

Broad incumbents

• Sato Pharmaceutical: Established Japanese OTC pharmaceutical manufacturer with household-name brands in cold remedies, gastrointestinal, and topical products. Comparable in OTC pharmacy distribution, though broader in scope and scale.
• Kobayashi Pharmaceutical: Major Japanese consumer health and OTC company with strong drugstore channel presence. Comparable overlap in OTC pharmacy retail and functional health products, though broader portfolio and much larger scale.
• Daiichi Sankyo Healthcare: OTC and consumer healthcare arm of Daiichi Sankyo, offering a broad range of cold remedies, gastrointestinal products, and supplements. Comparable in Japanese OTC pharmacy category presence; much larger and broader.
• Taiho Pharmaceutical: Major Japanese pharmaceutical company with consumer health (OTC, Kampō) division. Comparable in OTC drug manufacturing and pharmacy distribution, though primarily oncology-focused overall.
• Taisho Pharmaceutical: Large Japanese OTC pharmaceutical and consumer health company with broad portfolio including tonics, cold remedies, and energy drinks. Comparable in OTC categories like cold remedies and nutritional tonics, though much larger and more diversified.

Direct peers

• Tsumura & Co. Japan's largest Kampō medicine manufacturer, producing and distributing prescription and OTC Kampō formulations. Directly comparable as a Japanese Kampō-focused pharmaceutical company with a long product heritage and nationwide distributor/physician relationships.
• Yomeishu Seizo (Yomeishu Pharmaceutical): Long-established Japanese herbal tonic and Kampō-based health drink manufacturer. Direct overlap in the Kampō tonic and herbal health beverage category, including similar ginseng/herbal formulations and Japanese pharmacy distribution.
• Kracie Pharmaceutical (Kracie Holdings): Major Japanese Kampō and OTC pharmaceutical company with a broad portfolio of traditional herbal medicines and consumer health products. Comparable as a multi-channel Kampō brand operator serving both pharmacy and consumer channels.
• Kotaro Pharmaceutical (Kotaro Seiyaku): Japanese Kampō pharmaceutical manufacturer specializing in traditional Chinese medicine formulations. Similar mid-sized Japanese focused Kampō company with prescription and OTC overlap.
• Ohta Pharmaceutical (Ohta Seiyaku): Listed as a major distribution partner for the subject company. Japanese pharmaceutical manufacturer with OTC and health food overlap, comparable in pharmacy-channel product distribution.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/%E6%97%A5%E6%9C%AC%E8%A3%BD%E8%96%AC%E5%B7%A5%E6%A5%AD%EF%BC%88%E6%A0%AA%EF%BC%89

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about 日本製薬工業（株）