What Tofflon Life Science does

Tofflon Life Science (东富龙生命科技) is a Shanghai-headquartered bioprocessing technology supplier that provides integrated equipment, single-use consumables, chromatography resins, filtration products, and bio-reagents for pharmaceutical and biotechnology manufacturers. The company is a life science-focused division within Tofflon Technology Group Co., Ltd., which was founded in 1993 and listed on a Chinese stock exchange in 2010. Tofflon Life Science's product portfolio spans the full drug manufacturing workflow: upstream cell culture and fermentation systems (BRG Glass Bioreactor, SUB Single Use Bioreactor, CES Cell Expansion System), cell and gene therapy equipment (ATF Alternating Tangential Flow, SUC Single-use Cell Processor, GMP Cell Preparation Station), cryogenic storage, synthetic nanodelivery systems (LNP-060L Nanomedicine Production System, DFL-Oligo 150 Nucleic Acid Synthesizer), fill-finish solutions, chromatography resins (Protein A, Purose, Rigose, MMA/MMC series), serum-free culture media, and proprietary filtration products including Valpha® virus removal filters (LRV≥4 for MMV, ≥99% antibody recovery) and TanFlux® TFF cassettes built on independent membrane production capability.

The company operates a B2B enterprise sales model with quote-based pricing and multi-year contracts to pharmaceutical and biotech manufacturers. Its go-to-market targets five primary verticals: monoclonal antibody manufacturers, cell and gene therapy companies, vaccine manufacturers, viral vector producers, and mRNA/nucleic acid drug developers. Distribution is direct-sales driven with regional support via international offices in Singapore, India, Vietnam, Italy, Indonesia, and Australia (all established in 2021), plus manufacturing operations in India and Italy. R&D is anchored by the Hangzhou Research Institute (178,000 sqm under construction) and Chengdu Research Institute. Strategic partnerships include a 2024 collaboration with SINOBAY Biotech and a 2023 strategic cooperation agreement with Xinwan Bio for cell therapy culture media. The company's value proposition centers on supply chain security through localized high-end filtration manufacturing, integrated single-vendor workflow solutions, and cGMP-compliant equipment serving regulated biopharmaceutical production.

Name

Tofflon Life Science

Legal name

东富龙生命科技有限公司 (Tofflon Life Science Technology Co., Ltd.)

Website

https://tofflon-lifescience.com

Company type

Public

Founded year

1993

Operating status

Operating

Headcount range

1–10 employees

Short description

Tofflon Life Science is a Shanghai-headquartered bioprocessing supplier providing integrated equipment, consumables, chromatography resins, filtration products, and bio-reagents to pharmaceutical and biotech manufacturers across monoclonal antibody, cell/gene therapy, vaccine, viral vector, and mRNA drug development verticals globally.

Ownership category

akta.pro rank

Product category

Bioprocessing Equipment

NAICS

Biological Product (except Diagnostic) Manufacturing (325414), Medical Equipment and Supplies Manufacturing (3391), Analytical Laboratory Instrument Manufacturing (334516)

SIC

Biological Products, (No Disgnostic Substances) (2836), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Bioprocess Facility, Cleanroom & Utility Systems (HVAC, WFI, CIP/SIP, containment) (HLAAAJAJ)

akta.pro secondary industries

Aseptic Processing, Fill-Finish & Sterile Manufacturing Tech (isolators, lyophilization interfaces) (HLAAAJAG), mRNA & Nucleic Acid Manufacturing Services (mRNA/saRNA/Plasmid DNA) (HLAGAGAC)

Keywords

• Bioprocessing equipment
• Single-use technology
• Chromatography resins
• Pharmaceutical filtration
• Cell culture media

Headquarters

HQ city

Shanghai

HQ country

China

HQ region

Asia

Offices9 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Bioprocessing Equipment Sales: Sale of capital equipment including bioreactors, filling systems, cell therapy instruments, and cryogenic solutions to pharmaceutical and biotech manufacturers.
2. Single-use Consumables: Sale of single-use components including bioreactor bags, mixing bags, storage bags, filling systems, tubing assemblies, and filters for biopharmaceutical manufacturing processes.
3. Chromatography Resins: Sale of chromatography separation media including gel filtration, ion exchange, hydrophobic interaction, affinity, and multimodal chromatography resins.
4. Cell Culture Media and Reagents: Sale of serum-free cell culture media, supplements, and reagents for cell therapy, vaccine, and antibody manufacturing.
5. Filtration Products: Sale of filtration products including virus removal filters, tangential flow filtration cassettes, depth filters, and sterilization filters.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Tofflon Life Science manufactures and sells bioprocessing equipment (bioreactors, fermenters, cell expansion systems), single-use consumables (bags, tubing assemblies, filling systems), filtration products (virus removal filters, TFF cassettes, depth filters, sterilizing-grade filters), chromatography resins (Protein A, ion exchange, HIC, multimodal), and bio-reagents (serum-free cell culture media) to pharmaceutical and biotech manufacturers. The portfolio spans the full drug manufacturing lifecycle from upstream cell culture through downstream purification to fill-finish, with specialized solutions for monoclonal antibody, cell and gene therapy, vaccine, viral vector, and mRNA/nucleic acid drug production.

Product overview

Tofflon Life Science provides a comprehensive portfolio of bioprocessing equipment, single-use consumables, bio-reagents, chromatography resins, and filtration products for the biopharmaceutical and cell and gene therapy industries. The product portfolio includes: Bioprocessing Equipment (BRG Glass Bioreactor, PBS Parallel Bioreactor, SUB Single Use Bioreactor System, CES Cell Expansion System, Single-use Biological Swinger, SUF Single-use Fermentation Reactor System, SuBed-C Fixed Bed Bioreactor) for cell culture and fermentation; Cell and Gene Therapy Equipment (ATF Alternating Tangential Flow System, SUC Single-use Cell Processor, GMP Cell Preparation Station, CRF Controlled Rate Freezer, Cell Thawing System) for advanced therapy manufacturing; Cryogenic Solutions (Automatic Liquid Nitrogen Storage System) for biological sample storage; Synthetic Nanodelivery Systems (LNP-060L Nanomedicine Production System, DFL-Oligo 150 Nucleic Acid Synthesizer) for mRNA and nucleic acid therapeutics; Fill and Finish solutions including MiniKUFill Automatic Filling System; Filtration products (Valpha Virus Removal Filter, TanFlux II TFF Cassette, SaiClear Depth Filter, SaiPress Sterilizing-grade Liquid Filters, Filgiant Gas Filters, Felix Integrity Tester); Chromatography Resins (Protein A Series, Purose and Rigose series for gel filtration, ion exchange, HIC, affinity, and multimodal chromatography); Bio-reagents including Serum-Free MSC Culture Medium, NK Cell Culture Medium, T Lymphocyte Culture Medium, CHO and HEK293 Culture Media Series; and Single-use Consumables including Cell Culture Bags, Bioreactor Bags, Mixing Bags, and Filling Systems. The company supports the entire drug lifecycle from upstream cell culture through downstream purification and final fill.

Differentiator

Problem solved

Functional benefit

Brands

• Valpha: Virus removal filter product line for biological products
• Vshell
• TanFlux
• SaiClear
• SaiPress
• Filgiant
• PolySai
• Saiflow
• Purose
• Rigose
• Magose
• Pucarrier
• Tobitec
• LNP-060L
• DFL-Oligo 150

Products and services

• BRG Glass Bioreactor Glass bioreactor system for cell culture and fermentation processes in biopharmaceutical manufacturing.
• PBS Parallel Bioreactor Parallel bioreactor system for high-throughput cell culture screening and process development.
• SUB Single Use Bioreactor System Single-use bioreactor system for scalable biopharmaceutical production with reduced contamination risk.
• CES Cell Expansion System Automated cell expansion system for large-scale cell therapy and vaccine manufacturing.
• Single-use Biological Swinger Single-use swinging bioreactor for gentle cell culture mixing and suspension culture applications.
• SUF Single-use Fermentation Reactor System Single-use fermentation system for microbial and cell culture applications.
• SuBed-C Fixed Bed Bioreactor Fixed bed bioreactor system for high-density cell culture and productivity optimization.
• ATF Alternating Tangential Flow System Alternating tangential flow perfusion system for continuous cell culture and cell retention in bioprocessing.
• SUC Single-use Cell Processor Closed single-use cell processing system for cell therapy manufacturing.
• GMP Cell Preparation Station cGMP-compliant cell preparation workstation for cell therapy manufacturing.
• CRF Controlled Rate Freezer Controlled rate freezer for reproducible cell and biological sample cryopreservation.
• Cell Thawing System Automated cell thawing system for gentle and controlled recovery of cryopreserved cells.
• Automatic Liquid Nitrogen Storage System Automated cryogenic storage system for biological samples with inventory management.
• LNP-060L Nanomedicine Production System Lipid nanoparticle production system for mRNA and nucleic acid drug manufacturing.
• DFL-Oligo 150 Nucleic Acid Synthesizer Oligonucleotide synthesizer for research and production-scale nucleic acid synthesis.
• MiniKUFill Automatic Filling System Automated small-volume aseptic filling system for vials and syringes.
• Valpha Virus Removal Filter Virus removal filter designed to efficiently remove virus particles from biological products with MMV reduction rate LRV≥4 and antibody protein recovery rate ≥99%.
• Vshell Virus Pre-filter Virus pre-filter for upstream virus removal protection in biopharmaceutical processing.
• TanFlux II TFF Cassette Tangential flow filtration cassette for ultrafiltration and diafiltration in downstream processing.
• SaiClear Depth Filter Depth filter for clarification and impurity removal in biopharmaceutical production.
• SaiPress Sterilizing-grade Liquid Filter Sterilizing-grade liquid filter for bioburden reduction and final product filtration.
• Filgiant Sterilizing-grade Gas Filter PTFE sterilizing-grade gas filter for air and gas filtration in pharmaceutical manufacturing.
• Felix Integrity Tester Portable filter integrity testing device for quality control in pharmaceutical filtration.
• Serum-Free MSC Culture Medium Serum-free culture medium specifically developed for mesenchymal stem cell (MSC) expansion.
• Serum-Free NK Cell Culture Medium Kit Serum-free medium kit for natural killer (NK) cell expansion and activation.
• Serum-Free T Lymphocyte Culture Medium Serum-free medium for T lymphocyte and CAR-T cell expansion culture.
• CHO Cell Line Culture Medium Series Chemically defined, serum-free culture media for CHO cell line cultivation and recombinant protein production.
• HEK293 Cell Line Culture Medium Series Chemically defined medium for HEK293 cell culture used in viral vector and recombinant protein production.
• Protein A Series Antibody Purification Resins Protein A affinity chromatography resin for monoclonal antibody purification.
• Purose High Performance Series High-performance gel filtration chromatography resin for protein separation and purification.
• Single-use Cell Culture Bag Disposable cell culture bag for media storage, cell growth, and process fluid handling in biomanufacturing.
• Single-use Bioreactor Bag Single-use bioreactor bag for scalable cell culture applications in bioreactors.
• Single-use Filling System Complete single-use filling assembly for aseptic pharmaceutical filling operations.
• Single-use Mixing Bag Disposable mixing bag for buffer and media preparation in biopharmaceutical processes.

Quantifiable outcome

• Valpha® Virus Removal Filter achieves LRV≥4 for Mice Minute Virus (MMV) removal and ≥99% antibody protein recovery
• +1 more outcomes

Named customers1 record

Segments5 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Two partnerships are on record, tiered core.

• SINOBAY BiotechcoreStrategic or Co-development Partner · 11 November 2024Strategic partnership between SINOBAY Biotech and Tofflon Life Science announced in November 2024. The partnership focuses on collaboration in the biopharmaceutical manufacturing sector, combining SINOBAY's biotech capabilities with Tofflon's bioprocessing equipment and solutions.
• 鑫湾生物 (Xinwan Bio)coreStrategic or Co-development Partner · 20 December 2023Strategic cooperation agreement between Tofflon Life Science and Xinwan Bio signed in December 2023. Tofflon's T lymphocyte culture medium demonstrated superior performance in Xinwan Bio's immune cell projects with excellent purity and cell expansion results. Tofflon's culture medium will serve as the preferred choice for Xinwan Bio's clinical trials and market approval of cell therapy products.

Scale indicators2 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Eppendorf: Specializes in bioreactors, fermentation systems, and cell processing equipment for biopharma and academic markets. Competes with Tofflon's bioreactor (BRG, SUB, PBS) and cell expansion product lines, particularly in process development and small-to-mid scale production.
• Cytiva (Danaher): Global bioprocessing leader offering bioreactors, single-use systems, filtration, chromatography, and cell therapy equipment. Direct overlap with Tofflon across nearly every product category, with deeper market share and longer-tenured customer relationships in Western markets.
• Tosoh Bioscience: Major chromatography resin manufacturer with strong presence in ion exchange, hydrophobic interaction, and gel filtration media. Competes with Tofflon's Rigose, Purose, and multimodal chromatography resin product lines.
• Sartorius: German bioprocessing specialist with strong portfolios in bioreactors, single-use solutions, and filtration. Competes head-to-head with Tofflon in upstream equipment and consumables, particularly for cell and gene therapy applications.
• Asahi Kasei Medical (incl. Planova): Leading supplier of virus removal filters (Planova) and bioprocess filtration products. Direct competitor to Tofflon's Valpha® virus removal filter franchise in the downstream bioprocessing space.
• Pall Corporation (Danaher): Specializes in filtration, separation, and purification for biopharmaceutical manufacturing. Competes with Tofflon's TanFlux® TFF cassettes, depth filters, and sterilization filter product lines.

Broad incumbents

• Thermo Fisher Scientific: Diversified life sciences conglomerate with bioproduction capabilities (formerly Patheon) plus extensive lab instruments and consumables. Overlaps with Tofflon in cell therapy manufacturing equipment and bioprocessing consumables as part of a much broader portfolio.
• Merck KGaA (Life Science / MilliporeSigma): Operates one of the broadest bioprocessing portfolios globally through its Life Science sector, including filtration, single-use systems, chromatography, and cell culture media. Directly comparable to Tofflon's product range but at significantly larger scale.

Regional players

• WuXi Biologics: China-based global biologics CDMO with growing internal bioprocessing capabilities and supply partnerships. Relevant as a regional competitor and potential large customer in the Chinese biopharma ecosystem where Tofflon is most established.
• GenScript ProBio: Asia-Pacific focused CDMO offering cell therapy, viral vector, and biologics manufacturing services with proprietary bioprocessing equipment portfolios. Comparable as a regional competitor in gene/cell therapy equipment and consumables, primarily serving APAC customers.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks4 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/tofflon-lifescience

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Tofflon Life Science