What Rachael does

Selleck Chemicals LLC is a privately held U.S.-based supplier of research biochemicals and reagents, headquartered in Houston, Texas, with global operations spanning more than 20 countries through dedicated regional websites (including Korea, China, Japan, Australia, Germany, France, UK, and others). Founded in 2013, the company sells a catalog of small-molecule inhibitors, antibodies, proteins, kits, compound libraries, and bioreagents to academic, pharmaceutical, and biotechnology researchers worldwide. Its products are cited in Nature, Science, and Cell, and 17 Nobel Prize laureates have published 60 papers using Selleck reagents — a credential footprint that drives organic demand from the research community.

The core product platform is a 3,000+ SKU catalog organized by signaling pathway (PI3K/Akt/mTOR, JAK/STAT, MAPK, Epigenetics, Cell Cycle, DNA Damage/Repair, etc.), therapeutic area (multiple oncology indications plus diabetes, Alzheimer's, anti-aging), and product type (kinase inhibitors, molecular glues, PROTACs, ADC linkers, CFTR modulators, RNA methyltransferase inhibitors). Technical differentiators include high-purity products (97-99%+) with full Certificate of Analysis, NMR, and HPLC documentation; mutant-selective tool compounds such as Tersolisib (STX-478); pan-RAF-MEK molecular glues such as NST-628; and a comprehensive ADC linker portfolio for antibody-drug conjugate synthesis. All products are sold research-use-only.

Selleck operates a direct-to-consumer e-commerce model through country-specific storefronts with local language support, pay-as-you-go unit pricing, bulk-order availability, and temperature-controlled global shipping. Revenue derives from one-time catalog sales with no disclosed subscription or licensing component. The customer base is segmented horizontally across academic institutions, pharmaceutical/biotech companies, and disease-specific research programs. No external investors, funding rounds, or financial disclosures are present in the available data, and ownership is not publicly disclosed.

Name

Rachael

Legal name

Selleck Chemicals LLC

Website

https://selleck.kr

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

51–100 employees

Short description

Selleck Chemicals LLC is a privately held U.S. supplier of 3,000+ research biochemicals — inhibitors, antibodies, proteins, kits, and reagents — sold via 20+ country-specific e-commerce sites to academic, pharmaceutical, and biotechnology researchers worldwide.

Ownership category

akta.pro rank

Product category

Research Biochemicals and Reagents

NAICS

Other Chemical and Allied Products Merchant Wholesalers (424690), Drugs and Druggists' Sundries Merchant Wholesalers (42421)

SIC

Wholesale-Chemicals & Allied Products (5160), Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122), Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Impurity / Reference Standard Synthesis & Characterization (HLAGAHAG)

akta.pro secondary industry

Chiral / Asymmetric Synthesis & Complex Chemistry Services (HLAGAHAE)

Keywords

• Biochemical inhibitors
• Research reagents
• Kinase inhibitors
• Antibodies proteins kits
• Life sciences catalog

Headquarters

HQ city

Houston

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Research biochemicals and reagents sales: Selleck Chemicals generates revenue through the sale of biochemical inhibitors, antibodies, proteins, kits, and reagents to research institutions, pharmaceutical companies, and academic laboratories worldwide. Products are sold as catalog items with standard pricing for research use only.
2. Product catalog sales: Revenue from catalog products including kinase inhibitors, molecular biology reagents, cell biology products, and custom synthesis services for research applications.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Selleck Chemicals supplies a research-use-only catalog of biochemical inhibitors (kinase, CFTR, RAF/MEK, PDK, CDK, RNA methyltransferase), antibodies, proteins, kits, molecular glues/PROTACs, and ADC linkers to academic, pharmaceutical, and biotechnology research laboratories worldwide. Products are sold per-vial/unit with purity and activity documentation (COA, NMR, HPLC, IC50) through the company's e-commerce storefront and ~20 regional country-specific websites for in vitro and in vivo research, not for human use.

Product overview

Selleck Chemicals is a research biochemical supplier offering inhibitors, antibodies, proteins, kits, reagents, compound libraries, and bioreagents. The product portfolio includes kinase inhibitors (PI3K, RAF, MEK, PDK, CDK), CFTR modulators and inhibitors, RNA methyltransferase inhibitors, molecular glues for protein degradation, ADC linkers for antibody-drug conjugate synthesis, and carbohydrate metabolism modulators. The company supplies products used in cancer research, cystic fibrosis treatment development, metabolic disease research, and antiviral studies, with compounds cited in publications including Nature, Science, and Cell.

Differentiator

Problem solved

Functional benefit

Brands

• Selleck Korea: Korean regional website for Selleck Chemicals products and services

Products and services

• Tersolisib (STX-478) Highly potent, mutant-selective, allosteric inhibitor of PI3Kα targeting prevalent mutant forms including H1047R, with an IC50 of 9.4 nmol/L and 14-fold selectivity for mutant PI3Kα over wild-type. Sold as a research-use-only catalog item to academic, biotech, and pharmaceutical labs studying PI3K/Akt/mTOR signaling and oncology.
• Deutivacaftor (VX-561) Deuterated CFTR modulator (ivacaftor-D9) with an EC50 of 255 nM for CFTR potentiation in G551D/F508del HBE cells, sold as a research-use-only catalog item for cystic fibrosis treatment research.
• STC-15 Oral small-molecule inhibitor of the RNA methyltransferase METTL3 that inhibits tumor growth by activating anti-cancer immune responses associated with interferon signaling and synergizes with T-cell checkpoint blockade. Sold as a research-use-only catalog item to oncology and immunology researchers.
• RAF265 (CHIR-265) Selective C-Raf/B-Raf/B-Raf V600E inhibitor with IC50 of 3-60 nM and VEGFR2 phosphorylation inhibition at EC50 of 30 nM; induces cell-cycle arrest and apoptosis. Sold as a research-use-only catalog item for oncology and angiogenesis research.
• NST-628 Pan-RAF-MEK molecular glue that functions as a single-agent inhibitor of both RAF and MEK, blocking MEK phosphorylation and activation by RAF. Sold as a research-use-only catalog item for MAPK-pathway and oncology research.
• MY-1B Covalent inhibitor of the RNA methyltransferase NSUN2 with an IC50 of 1.3 μM, stereoselectively targeting active-site cysteine C271 of NSUN2 for RNA-methylation research. Sold as a research-use-only catalog item to epigenetics and RNA-biology researchers.
• ADC Linkers Category of antibody-drug-conjugate (ADC) synthesis reagents including DSS Crosslinker, MC-VC-PAB-PNP, MC-Val-Cit-PAB, Fmoc-Val-Ala-PAB, Boc-Val-Cit-PAB-PNP, Sulfo-SMCC sodium, Succinic anhydride, Fmoc-Val-Cit-PAB, DSP Crosslinker, and PDEC-NB. Sold as research-use-only catalog items to ADC discovery and bioconjugation groups.
• Molecular Glues Category of molecular-glue degraders and cereblon modulators including Lenalidomide, Pomalidomide, Iberdomide, VAV1 degrader-3, XYD049, HbF inducer 2, dCeMM1, Thalidomide, CC-90009, Mezigdomide, MRT-2359, DEG-77, Lenalidomide hemihydrate, NVP-DKY709, GBD-9, SJ6986, PT-179, HGC652, and NST-628. Sold as research-use-only catalog items for targeted protein degradation research.
• PDK Inhibitors Phosphoinositide-dependent kinase (PDK) inhibitor catalog including BX-795 (PDPK1 inhibitor), JX06 (PDK1 covalent inhibitor), Sodium Dichloroacetate (PDK2/PDK4 inhibitor), and KPLH1130, sold as research-use-only catalog items for kinase, metabolism, and inflammation research.
• Compound screening libraries Multi-pathway screening libraries grouped by signaling area (PI3K/Akt/mTOR, Epigenetics, JAK/STAT, MAPK, Cell Cycle, DNA Damage/Repair, etc.) and disease area, supplied as catalog items for high-throughput screening and drug-discovery campaigns.
• Antibodies (primary, in vivo functional, biosimilar) Catalog of primary antibodies, in vivo functional (inhibitory) antibodies, and biosimilar therapeutic antibodies supplied as research-use-only catalog items to academic and pharmaceutical laboratories.
• Biological reagents (bioreagents) Catalog of biological reagents, proteins, and kits supplied as research-use-only items alongside inhibitors and antibodies for life-science research workflows.

Quantifiable outcome

• 17 Nobel Prize laureates have published 60 papers using Selleck products
• +2 more outcomes

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• AdooQ Bioscience: Niche research-use inhibitor and biochemical catalog serving academic and early-stage biotech discovery customers. Smaller and more specialty than Selleckchem but competes for the same catalog dollars with overlapping pathway coverage.
• MedChemExpress (MCE): China-headquartered catalog supplier of research-use biochemical inhibitors, modulators, and natural products serving the same academic and pharma discovery customers as Selleckchem. Often cited as the largest direct competitor on SKU breadth and pricing.
• Cell Signaling Technology (CST): Specialty antibody and reagent supplier focused on cell signaling, with adjacent kinase-inhibitor offerings for translational research. Overlaps with Selleckchem in pathway-targeted research reagents and the same PI3K/MAPK/JAK pathway biology.
• Enzo Life Sciences: Research reagents and assay kits supplier covering biochemicals, antibodies, and small-molecule tools. Comparable catalog model and academic/biotech customer base to Selleckchem.
• Tocris Bioscience: Established research-use biochemicals catalog (kinase inhibitors, ion channel tools, neurotransmitters) owned by Bio-Techne. Closest pure-play analog by catalog positioning, branding, and academic customer base.
• Cayman Chemical: Catalog supplier of research biochemicals, assay kits, antibodies, and natural products to academic and pharma researchers. Overlaps with Selleckchem on inhibitors, reference standards, and disease-area research reagents.
• Santa Cruz Biotechnology: Long-standing research-reagent catalog spanning antibodies, biochemicals, and labware to academic and biotech customers. Directly comparable in breadth, channel mix (catalog + online), and customer composition.

Broad incumbents

• Sigma-Aldrich (MilliporeSigma / Merck KGaA): Global incumbent for research chemicals, reagents, and analytical standards — including the Sigma-Aldrich and Supelco brands. Overlaps with Selleckchem on inhibitors, standards, and biochemicals but operates across a far broader portfolio.
• Bio-Techne: Public life-sciences tools holding company owning Tocris, R&D Systems, ProteinSimple, and other research-reagent brands. Comparable through its Tocris subsidiary and an indication of the strategic exit path for specialty catalogs like Selleckchem.
• Abcam: Research antibody specialist serving academic and pharma researchers globally. Adjacent to Selleckchem on the antibody category and overlapping customer pool, but with negligible small-molecule inhibitor catalog.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/RachaelJon65966
• Facebookfacebook.com/profile.php

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Rachael