gammaCore

What gammaCore does

gammaCore is the commercial brand of electroCore, Inc., a privately held medical device company headquartered in Rockaway, New Jersey, that develops and sells a non-invasive vagus nerve stimulation (nVNS) device for the treatment and prevention of headache disorders. The handheld device delivers proprietary sine wave electrical pulses through the skin of the cervical (neck) region to activate the vagus nerve, intended to block pain signaling without surgery, implantation, or systemic drugs. The product family — including gammaCore Sapphire and gammaCore Emerald variants, plus proprietary conductive gel — is delivered via prescription only and is cleared by the FDA for 6 indications: preventive and acute treatment of migraine in patients age 12 and older, adjunctive prevention and acute treatment of episodic cluster headache in adults, and treatment of hemicrania continua and paroxysmal hemicrania in adults.

Name

gammaCore

Legal name

electroCore, Inc.

Website

https://gammacore.com

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Short description

gammaCore (electroCore, Inc.) is a private medical device company that sells a prescription-only, handheld non-invasive vagus nerve stimulator for treating and preventing migraine, cluster headache, and related headache disorders in adults and adolescents, distributed in the US, UK, Australia, and Canada.

Ownership category

akta.pro rank

Product category

Non-invasive neuromodulation medical devices

NAICS

Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Implantable Neuromodulation & Neurostimulation (SCS/DBS/VNS/PNS) (HLAHAEAK)

akta.pro secondary industry

Headache & Migraine Medicine (HLAKAIAE)

Keywords

• Non-invasive vagus nerve stimulation
• Neuromodulation medical devices
• Migraine treatment devices
• Cluster headache therapy
• Headache pain management

Headquarters

HQ city

Rockaway

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Operations, Personnel, Marketing or Sales, Infrastructure

Revenue model

1. Medical Device Hardware Sales: gammaCore sells a handheld medical device (gammaCore Sapphire/Emerald) that comes preloaded with therapy duration (3, 12, or 36 months options). The device requires prescription and is ordered through healthcare providers or VA systems.
2. Conductive Gel Refills: Ongoing sales of proprietary conductive gel tubes required for device operation. Patients reorder gel as consumable supply.
3. Device Refills/Refill Cards: Patients can reload their gammaCore device with additional treatment sessions using refill cards, providing recurring revenue from existing customers.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels7 records

Core offering

gammaCore is a handheld, prescription-only, non-invasive vagus nerve stimulation (nVNS) medical device that delivers gentle proprietary sine wave electrical stimulation through the skin of the neck to treat and prevent migraine (ages 12+), cluster headache, hemicrania continua, and paroxysmal hemicrania. The device is sold directly to patients through prescribing healthcare providers, including a dedicated VA/government channel, and generates recurring revenue through conductive gel consumables and refill cards for additional treatment sessions.

Product overview

gammaCore is a single product line consisting of handheld non-invasive vagus nerve stimulator (nVNS) medical devices designed to treat and prevent headache pain. The product family includes gammaCore Sapphire and gammaCore Emerald as device variants, along with conductive gel as a required accessory. All devices work identically using gentle electrical stimulation applied to the vagus nerve through the neck skin to provide drug-free relief for migraine, cluster headache, and other headache conditions.

Differentiator

Problem solved

Functional benefit

Products and services

• gammaCore (nVNS device) Handheld, rechargeable, non-invasive vagus nerve stimulator (nVNS) prescription medical device that delivers gentle proprietary sine wave electrical stimulation through the skin of the neck to treat and prevent migraine (ages 12+), cluster headache, hemicrania continua, and paroxysmal hemicrania without pills, injections, or drug-like side effects. Available in 3-month, 12-month, and 36-month therapy duration options, supports up to 24 stimulations per day, and ships with 6 conductive gel tubes.
• gammaCore Sapphire Variant of the gammaCore nVNS handheld device marketed as gammaCore Sapphire in the United States, United Kingdom, Australia, and Canada for the treatment and prevention of migraine and cluster headache.
• gammaCore Emerald Variant of the gammaCore nVNS handheld device marketed as gammaCore Emerald in the United States for the treatment and prevention of migraine and cluster headache.
• gammaCore Refill Cards Refill cards that allow existing gammaCore patients to reload their device with additional treatment sessions, providing recurring subscription-style revenue from the existing patient base.
• gammaCore Conductive Gel Proprietary conductive gel supplied in tubes (6 tubes shipped with each device) that facilitates electrical signal transmission from the gammaCore device to the vagus nerve; reordered by patients as a recurring consumable supply.

Quantifiable outcome

• 40% decrease in cluster headache attack frequency
• +7 more outcomes

Named customers7 records

Segments5 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

One partnership is on record.

• Lovell Government ServicescoreChannel Partner/ Reseller/ DistributorLovell Government Services serves as the government ordering partner for gammaCore within the VA system. They handle procurement for VA facilities (CAGE 71G35, EIN 46-3795418, UEI MNH3STM1FTS6) and process orders for SDVOSB (Service-Disabled Veteran-Owned Small Business) category. Orders can be submitted by phone, fax, or email.

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Inspire Medical Systems: Inspire Medical Systems is an established implantable neurostimulator company (hypoglossal nerve stimulation for sleep apnea). It is comparable as a public, scaled neuromodulation medical device business using electrical stimulation to treat chronic conditions.
• Nevro: Nevro manufactures spinal cord stimulation (HF10 therapy) systems for chronic pain. Comparable as a neuromodulation device company targeting chronic pain conditions through electrical stimulation, addressing patient populations with limited treatment alternatives similar to gammaCore's headache patients.
• LivaNova: LivaNova is the established leader in vagus nerve stimulation with an implantable VNS therapy (originally for epilepsy, with depression and other indications). Although gammaCore is non-invasive and LivaNova is implantable, both target the vagus nerve mechanism and overlap in clinical literature and prescribing physicians.
• Boston Scientific Neuromodulation: Boston Scientific markets spinal cord stimulators and deep brain stimulation systems for chronic pain and movement disorders. Comparable as a large diversified neuromodulation incumbent with overlapping physician channels (neurologists, pain specialists) used by gammaCore.
• Axonics: Axonics develops implantable sacral and tibial neuromodulation devices for bladder/bowel dysfunction. It is a comparable neuromodulation medical device company targeting chronic conditions through electrical stimulation, though focused on urology rather than headache.
• Abbott Neuromodulation: Abbott (formerly St. Jude Medical) operates a large neuromodulation business including spinal cord stimulation and dorsal root ganglion therapy for chronic pain. Comparable as a broad incumbent in the implantable neurostimulation space competing for the same neurology patient channel as gammaCore.

Direct peers

• Theranica: Theranica manufactures Nerivio, a wearable remote electrical neuromodulation device worn on the arm to treat and prevent migraine. Like gammaCore, it is a prescription-only, non-invasive neurostimulation device targeting episodic and chronic migraine patients via headache specialists.
• eNeura: eNeura makes the sTMS mini, a single-pulse transcranial magnetic stimulation device FDA-cleared for acute and preventive treatment of migraine. It is a directly competing non-invasive prescription neurostimulator in the same headache indication space as gammaCore.
• Cefaly: Cefaly makes an external trigeminal nerve stimulation device for migraine prevention and acute treatment. It is the closest direct non-invasive neurostimulator competitor to gammaCore, prescribed through the same headache-specialist channel for the same migraine patient population.

Emerging players

• Cala Health: Cala Health makes wearable non-invasive transcutaneous afferent patterned stimulation (TAPS) therapy initially for essential tremor, with migraine and other neurology indications in development. Comparable as an emerging non-invasive prescription neurostimulator company expanding from one indication into adjacent neurology use cases.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtwitter.com/ElectroCoreVNS
• YouTubeyoutube.com/user/ElectroCoreMedical
• Facebookfacebook.com/gammaCore-Sapphire-152365123593748
• LinkedInlinkedin.com/company/660025
• Instagraminstagram.com/gammacore

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about gammaCore