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CryoBio

Full company profile

uuid00pytc3

Namestring
CryoBio
Legal namestring
CryoBio
Websiteurl
cryo.bio
Company typeenum
Private
Founded yearint
2025
Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
1–10
akta.pro rankint
HeadquartersIthaca, United States
HQ citystring
Ithaca
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
agricultural biotechnology, frost protection, crop protection, biological spray, antifreeze proteins
Product category
Agricultural Biological Products
Social media profiles1 record
GTM motion1 record

Each record includes

Type, Description, Source

Revenue model1 record
1Frost Protection Spray Product
TypeOne Time License
Description

CryoBio develops and sells a sprayable biological frost protection product for crops. As a pre-seed company, they are transitioning from lab validation to on-farm trials with plans to commercialize their product for farmers facing frost damage.

igrownews.com
Marketing channels5 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components6 values
Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

CryoBio develops and manufactures a sprayable, food-safe biological frost protection formulation for crops. The product is inspired by naturally occurring antifreeze molecules and prevents ice formation at the molecular level, protecting crops from sub-zero temperatures. Manufacturing is carried out using a microbial fermentation platform, and the spray is designed for use with standard agricultural equipment.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 5 values shown
  • Frost protection up to 8°C compared to 1-2°C maximum for current technologies
+4 more records
Product overview1 text field

CryoBio offers a single unified product: a biological frost protection spray. The company is building the first crop spray that can protect against extreme frost by preventing ice formation at the molecular level. The spray is inspired by naturally occurring antifreeze molecules and is designed to be sprayable, food-safe, and biodegradable, allowing crops to withstand sub-zero temperatures without damage.

Scale indicator8 records

Each record includes

Type, Value, Description, Source

Partnership4 partners
Strategic tierCoreTypeStrategic or Co-development Partner
Description

CryoBio was founded in 2025 as a spin-out from Marble, indicating a close developmental relationship and shared technology origin.

Strategic tierMinorTypeStrategic or Co-development Partner
Description

Listed among supporters of CryoBio, indicating potential research collaboration or academic partnership.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

CryoBio graduated from Creative Destruction Lab of the Rockies accelerator program, receiving mentorship and support for scaling their technology.

Strategic tierMinorTypeStrategic or Co-development Partner
Description

Anshu Kumari, CryoBio's Research Scientist, was formerly employed at the Boyce Thompson Institute, indicating potential research collaboration.

Recent move7 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeBroad incumbent
Description

Syngenta is a global crop protection and seeds major, increasingly investing in biological alternatives to its traditional chemistry portfolio. Its scale and distribution make it the primary incumbent CryoBio must convince or partner with as it scales.

TypeDirect peer
Description

Indigo Ag markets microbial seed coatings and foliar biologicals that improve crop resilience to environmental stress. The biological-crop-protection business model and go-to-market through agricultural distribution channels directly parallel CryoBio's approach.

TypeDirect peer
Description

Pivot Bio develops microbial-based crop nutrition and protection products using fermentation-derived biology. Like CryoBio, it sells biological inputs to row-crop and specialty growers as a replacement for synthetic chemicals.

TypeBroad incumbent
Description

FMC is a global agricultural sciences company with a portfolio of crop protection products, including biologicals acquired from DuPont. Its GTM footprint in fruit and vegetable growers overlaps directly with CryoBio's vineyard and orchard targets.

TypeEmerging player
Description

Vestaron develops peptide-based biopesticides as alternatives to synthetic insecticides, sharing CryoBio's positioning of a science-driven, fermentation-derived biological replacing conventional crop chemistry in specialty crops.

TypeBroad incumbent
Description

BASF Agricultural Solutions is a top-tier crop protection incumbent with an expanding biologicals offering and global distribution. It is a relevant comparison point for go-to-market scale and competitive threat to CryoBio's specialty positioning.

TypeEmerging player
Description

Sound Agriculture develops on-demand crop inputs (including a foliar spray that activates the plant microbiome) that reduce dependence on synthetic fertilizers. It addresses similar grower pain points through a spray-based biological product, though focused on nutrient efficiency rather than frost.

TypeDirect peer
Description

AgBiome discovers and commercializes microbial and biological crop protection products, leveraging a large microbial strain library. Its product categories (biopesticides, biologicals for stress tolerance) overlap with CryoBio's antifreeze-biology platform.

TypeDirect peer
Description

Marrone Bio (now part of Bioceres Crop Solutions) manufactures biological crop protection and plant health products. It is a direct competitor in selling biologically derived spray products to specialty and row-crop growers.

TypeBroad incumbent
Description

Bayer's Crop Science division is the largest agricultural inputs company globally, with a portfolio of crop protection chemicals and an emerging biologicals pipeline. CryoBio competes for the same specialty-crop grower wallet but as a tiny niche entrant against a broad incumbent.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat4 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers6 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment2 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature4 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles4 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds1 record

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors6 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

CryoBio

Agricultural Biological Productscryo.bio

CryoBio firmographics

Firmographics
Name
CryoBio
Legal name
CryoBio
Website
https://cryo.bio
Company type
Private
Founded year
2025
Operating status
Operating
Headcount range
1–10 employees
Ownership category
akta.pro rank

Where CryoBio is headquartered

Location

Headquarters

HQ city
Ithaca
HQ country
United States
HQ region
North America

Offices1 record

Markets served

CryoBio business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure

Revenue model

  1. Frost Protection Spray Product: CryoBio develops and sells a sprayable biological frost protection product for crops. As a pre-seed company, they are transitioning from lab validation to on-farm trials with plans to commercialize their product for farmers facing frost damage.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

CryoBio product offering

Product offering

Core offering

CryoBio develops and manufactures a sprayable, food-safe biological frost protection formulation for crops. The product is inspired by naturally occurring antifreeze molecules and prevents ice formation at the molecular level, protecting crops from sub-zero temperatures. Manufacturing is carried out using a microbial fermentation platform, and the spray is designed for use with standard agricultural equipment.

Product overview

CryoBio offers a single unified product: a biological frost protection spray. The company is building the first crop spray that can protect against extreme frost by preventing ice formation at the molecular level. The spray is inspired by naturally occurring antifreeze molecules and is designed to be sprayable, food-safe, and biodegradable, allowing crops to withstand sub-zero temperatures without damage.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

  • Frost protection up to 8°C compared to 1-2°C maximum for current technologies
  • +4 more outcomes

Companies that use CryoBio

Customer profile

Named customers6 records

Segments2 records

Ideal customer profiles2 records

CryoBio technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature4 records

CryoBio partnerships and signals

Strategic signal

Partnerships

Four partnerships are on record, tiered core and minor.

  • MarblecoreStrategic or Co-development PartnerCryoBio was founded in 2025 as a spin-out from Marble, indicating a close developmental relationship and shared technology origin.
  • Cornell UniversityminorStrategic or Co-development PartnerListed among supporters of CryoBio, indicating potential research collaboration or academic partnership.
  • Creative Destruction LabcoreStrategic or Co-development PartnerCryoBio graduated from Creative Destruction Lab of the Rockies accelerator program, receiving mentorship and support for scaling their technology.
  • Boyce Thompson InstituteminorStrategic or Co-development PartnerAnshu Kumari, CryoBio's Research Scientist, was formerly employed at the Boyce Thompson Institute, indicating potential research collaboration.

Scale indicators8 records

Recent moves7 records

Expansion highlights5 records

CryoBio competitors and assessment

Company assessment

Broad incumbents

  • Syngenta: Syngenta is a global crop protection and seeds major, increasingly investing in biological alternatives to its traditional chemistry portfolio. Its scale and distribution make it the primary incumbent CryoBio must convince or partner with as it scales.
  • FMC Corporation: FMC is a global agricultural sciences company with a portfolio of crop protection products, including biologicals acquired from DuPont. Its GTM footprint in fruit and vegetable growers overlaps directly with CryoBio's vineyard and orchard targets.
  • BASF Agricultural Solutions: BASF Agricultural Solutions is a top-tier crop protection incumbent with an expanding biologicals offering and global distribution. It is a relevant comparison point for go-to-market scale and competitive threat to CryoBio's specialty positioning.
  • Bayer Crop Science: Bayer's Crop Science division is the largest agricultural inputs company globally, with a portfolio of crop protection chemicals and an emerging biologicals pipeline. CryoBio competes for the same specialty-crop grower wallet but as a tiny niche entrant against a broad incumbent.

Direct peers

  • Indigo Ag: Indigo Ag markets microbial seed coatings and foliar biologicals that improve crop resilience to environmental stress. The biological-crop-protection business model and go-to-market through agricultural distribution channels directly parallel CryoBio's approach.
  • Pivot Bio: Pivot Bio develops microbial-based crop nutrition and protection products using fermentation-derived biology. Like CryoBio, it sells biological inputs to row-crop and specialty growers as a replacement for synthetic chemicals.
  • AgBiome: AgBiome discovers and commercializes microbial and biological crop protection products, leveraging a large microbial strain library. Its product categories (biopesticides, biologicals for stress tolerance) overlap with CryoBio's antifreeze-biology platform.
  • Marrone Bio Innovations: Marrone Bio (now part of Bioceres Crop Solutions) manufactures biological crop protection and plant health products. It is a direct competitor in selling biologically derived spray products to specialty and row-crop growers.

Emerging players

  • Vestaron: Vestaron develops peptide-based biopesticides as alternatives to synthetic insecticides, sharing CryoBio's positioning of a science-driven, fermentation-derived biological replacing conventional crop chemistry in specialty crops.
  • Sound Agriculture: Sound Agriculture develops on-demand crop inputs (including a foliar spray that activates the plant microbiome) that reduce dependence on synthetic fertilizers. It addresses similar grower pain points through a spray-based biological product, though focused on nutrient efficiency rather than frost.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

CryoBio social profiles

Digital presence

CryoBio financial estimates

Financial estimate

Revenue estimate

Valuation estimate

CryoBio leadership team

Management profile

Number of profiles

Profiles4 records

CryoBio funding detail

Funding detail

Funding overview

Funding rounds1 record

Investors6 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

CryoBio M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about CryoBio

What does CryoBio do?

CryoBio develops and manufactures a sprayable, food-safe biological frost protection formulation for crops. The product is inspired by naturally occurring antifreeze molecules and prevents ice formation at the molecular level, protecting crops from sub-zero temperatures. Manufacturing is carried out using a microbial fermentation platform, and the spray is designed for use with standard agricultural equipment.

Is CryoBio a public or private company?

CryoBio is a private company. It is classified as venture growth investor backed and is currently operating.

When was CryoBio founded?

CryoBio was founded in 2025. It employs 1 to 10 people.

Where is CryoBio based?

CryoBio is headquartered in Ithaca, United States, in the North America region.

How does CryoBio make money?

One revenue line is on record: frost Protection Spray Product.

Who are CryoBio's main competitors?

Broad incumbents on record are Syngenta, FMC Corporation, BASF Agricultural Solutions and Bayer Crop Science. Direct peers are Indigo Ag, Pivot Bio, AgBiome and Marrone Bio Innovations. Emerging players are Vestaron and Sound Agriculture.

Does CryoBio have an API?

No public API is recorded for CryoBio.

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Live signals
YahooCryoBio CEO Murli Manohar talks CNY-based startup competing in Grow-NYMurli Manohar, CEO of CryoBio, spoke about his Ithaca-based startup that develops sprays to protect crops from frost. The startup is one of four local finalists in the Grow-NY competition, which offers up to $1 million in prizes.iGrow NewsCryoBio Raises $1.3M Pre-Seed Round to Develop Frost Protection SprayCryoBio has raised $1.3 million in an oversubscribed pre-seed funding round from investors including Ag Ventures Alliance, NY Ventures, Launch NY, FuzeHub, and impact-focused angel investors. The company, founded in 2025 as a spin-out from Marble, is developing a sprayable, food-safe frost protection product inspired by naturally occurring antifreeze molecules to address late-spring frost crop losses estimated at up to $30 billion annually across North America and Europe. The funding will support the company's transition from lab validation to on-farm trials.AgFunderNewsAntifreeze for orchards? CryoBio nets $1.3m to develop novel approach to frost protectionCryoBio, a New York-based startup, has raised a $1.3 million pre-seed round to develop and commercialize a novel frost protection solution for high-value crops such as apples and grapes. The technology engineers microbes to produce antifreeze proteins inspired by animals adapted to subzero temperatures, which bind to ice crystals and prevent them from forming larger, damaging crystals. The company plans to conduct field trials in New York, Washington, and Canada before launching with growers in 2027.AGDAILYLouisiana's FarmMind wins $100K in Ag Innovation ChallengeFarmMind, a Louisiana-based ag-tech startup, won the $100,000 grand prize at the 12th annual Farm Bureau Ag Innovation Challenge at the 2026 American Farm Bureau Convention for its AI-powered all-in-one agricultural management platform. The platform consolidates farming workflows including field notes, GIS management, regulatory compliance, financial tracking, and real-time agronomic insights into a single system designed to make advanced technology accessible to agricultural professionals. KiposTech of Pennsylvania was named runner-up and received $25,000 for its plasma-based poultry production technology, while CryoBio of New York and Vivid Machines of Washington each received $10,000 as finalists.FarmsAg Innovation Challenge Final Four 2026 LeadersThe American Farm Bureau Federation has selected four finalists for the 2026 Ag Innovation Challenge, a startup competition to be held on January 11 in Anaheim, California, with prize money of $100,000 for the winner and $25,000 for the runner-up. The finalists include CryoBio (frost protection technology from New York), FarmMind (AI-powered farm management platform from Louisiana), KiposTech (plasma-based poultry health systems from Pennsylvania), and Vivid Machines (AI tools for fruit growers from Washington). The competition, now in its twelfth year, is supported by Farm Credit, Bayer, John Deere, and other sponsors, and provides entrepreneurs an opportunity to present agricultural innovation solutions to investors and industry leaders.Grain JournalAg Innovation Challenge: Meet the Four Teams Vying for the Top PrizeThe 2026 Ag Innovation Challenge will feature four finalist teams pitching their ideas at the American Farm Bureau Convention in Anaheim, California on January 12, 2026. The competition, now in its 12th year, offers a total prize of $125,000 for the top innovations in agricultural technology. Participating teams include CryoBio, FarmSmarter.ai, KiposTech, and Vivid Machines, each developing innovative solutions to improve food production and agricultural practices.