ALS ONE
ALS ONE is a Massachusetts-based nonprofit that unites ALS researchers, clinicians, care providers, corporate leaders, and affected families through Research, Care, and Fundraising pillars to accelerate ALS treatment discovery and deliver resources to the ALS community.
- Company typePrivate
- Founded2015
- HeadquartersWhitman, United States
- Headcount1–10
- GTM typeB2B and B2C
- OfferingServices
What ALS ONE does
ALS ONE is a Massachusetts-based nonprofit organization founded around 2015 that unites world-leading ALS researchers, clinicians, care providers, corporate leaders, and families affected by ALS to accelerate treatment discovery and deliver practical care resources. It operates through three integrated pillars: Research (a collaborative partnership drawing on ALS Therapy Development Institute, UMass Medical School, Massachusetts General Hospital / Healey Center for ALS, and Compassionate Care ALS), Care (provision of equipment, resources, and support services to families living with ALS), and Fundraising (donation campaigns that underwrite both research and care programs).
Its core technology stack is non-software: the principal proprietary contribution disclosed is PERLA®, a new class of organ preservation solution (PPS) co-developed with Barcelona-based IDIBAPS that has received CE marking for clinical use in organ transplantation, signaling activity beyond pure ALS into adjacent translational research. The organization is community-led, headcount is 1–10, and revenue is sourced from donations and fundraising rather than commercial product sales; services to families are provided at no cost.
On February 11, 2026, ALS ONE announced a strategic integration with the ALS Network under which ALS ONE will become part of the ALS Network — combining Massachusetts-based research strength and Salesforce-linked corporate technology access with the ALS Network's national operational scale (California, Hawaii, and beyond). Chairman Mark Sullivan (Salesforce President/CRO of Regulated Industries) and Board Member Scott Gosnell will join the ALS Network Board of Directors, with Michael Braun as Advisory Trustee; the integration is expected to close in 2026 pending state and federal regulatory approvals.
ALS ONE firmographics
Firmographics- Name
- ALS ONE
- Legal name
- ALS ONE
- Website
- https://ALSONE.org
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- ALS ONE is a Massachusetts-based nonprofit that unites ALS researchers, clinicians, care providers, corporate leaders, and affected families through Research, Care, and Fundraising pillars to accelerate ALS treatment discovery and deliver resources to the ALS community.
- Ownership category
- akta.pro rank
ALS ONE industry classification
Industry- Product category
- Nonprofit Disease Research and Patient Care
- NAICS
- Voluntary Health Organizations (813212), Other Individual and Family Services (624190)
- SIC
- Services-Misc Health & Allied Services, Nec (8090)
- akta.pro primary industry
- Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS) (BPAGACAA)
- akta.pro secondary industry
- Health & Medical Research Grantmaking Foundations (BPAGAKAL)
Keywords
Where ALS ONE is headquartered
LocationHeadquarters
- HQ city
- Whitman
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
ALS ONE business model
Business model- GTM type
- B2B and B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Others
Revenue model
- Donations and Fundraising: As a nonprofit organization, ALS ONE raises funds through donations, fundraising campaigns, and charitable contributions to support ALS research and care programs
Go-to-market motion1 record
Distribution channels2 records
Marketing channels4 records
ALS ONE product offering
Product offeringCore offering
ALS ONE is a Massachusetts-based nonprofit organization that funds ALS research and delivers care resources to individuals and families impacted by ALS. It operates through three program pillars—Research, Care, and Fundraising—bringing together leading ALS researchers, clinicians, care providers, corporate leaders, and families under a shared mission to accelerate treatment discovery, provide critical equipment and resources, and foster a connected community.
Product overview
ALS ONE is a Massachusetts-based nonprofit organization that operates through three integrated pillars: Research (collaborative partnership of world-leading ALS researchers from institutions including ALS Therapy Development Institute, UMass Medical School, Massachusetts General Hospital, and Compassionate Care ALS), Care (providing critical equipment, resources, and support services for people living with ALS), and Fundraising (critical funding to advance united research and care initiatives). The organization unites researchers, clinicians, care providers, corporate leaders, and families impacted by ALS to accelerate treatment discovery and provide immediate practical support. ALS ONE is currently undergoing a strategic integration with the ALS Network (expected to complete in 2026) to expand national impact while maintaining its Massachusetts research partnerships.
Differentiator
Problem solved
Functional benefit
Products and services
- Research A collaborative partnership of world-leading ALS researchers focused on finding a cure, leveraging expertise from leading Massachusetts institutions including ALS Therapy Development Institute, UMass Medical School, Massachusetts General Hospital (Healey Center for ALS), and Compassionate Care ALS.
- Care Provision of critical care, essential equipment, technology, and support resources for individuals and families affected by ALS, delivered through the Compassionate Care ALS (CCALS) partnership.
- Fundraising Charitable fundraising initiatives to support ALS research and care programs, enabling collaboration among researchers, clinicians, caregivers, corporate leaders, and families through individual donations, corporate sponsorships, and foundation grants.
Quantifiable outcome
- Expanded national impact through integration with ALS Network
- +1 more outcomes
Companies that use ALS ONE
Customer profileSegments2 records
Ideal customer profiles3 records
ALS ONE technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature1 record
ALS ONE partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core and minor.
- ALS NetworkcoreStrategic integration where ALS ONE becomes part of the ALS Network. The combination unites ALS ONE's Massachusetts-based research strength and corporate technology expertise with the ALS Network's national operational scale. Integration expected to complete in 2026 pending regulatory approvals. ALS ONE board members will join ALS Network Board of Directors.
- Massachusetts General Hospital (MGH)coreKey research partner hosting the Healey Center for ALS. Dr. Merit Cudkowicz serves as Executive Director of Mass General Brigham Neuroscience Institute and Director of the Sean M. Healey & AMG Center for ALS. MGH researchers collaborate through ALS ONE's partnership model.
- ALS Therapy Development InstitutecoreLeading ALS research institution included in ALS ONE's collaborative partnership of top ALS experts from Massachusetts institutions.
- UMass Medical SchoolcoreKey Massachusetts research institution partner in ALS ONE's collaborative research partnership focused on therapeutic development.
- Compassionate Care ALS (CCALS)coreCare organization partner providing technology, equipment and support services. Founder Ron Hoffman advocates for connecting scientific progress with practical support for ALS families.
- IDIBAPS (Barcelona)minorBarcelona-based research institute that collaborated with ALS (ALS ONE) to develop PERLA®, a new class of organ preservation solution. PERLA® received CE marking for clinical use in organ transplantation.
- SalesforceminorMark Sullivan, President and CRO of Regulated Industries at Salesforce, serves as Chairman of the ALS ONE Board of Directors. Salesforce network provides technology connections and corporate funding opportunities for ALS research.
Scale indicators2 records
Recent moves6 records
Expansion highlights5 records
ALS ONE competitors and assessment
Company assessmentDirect peers
- ALS Therapy Development Institute: Boston-based ALS drug discovery nonprofit that is both a research partner of ALS ONE and a comparable organization with translational science as its core mission.
- ALS Association: The largest U.S. ALS-focused nonprofit, funding research, care services, and advocacy nationwide. Directly comparable mission, donation-driven model, and disease-specific focus.
- Target ALS: ALS-focused nonprofit accelerating therapeutic development through partnerships and core facilities. Comparable translational research funding mission.
- ALS Network: California-based ALS nonprofit (formerly ALS Golden West) that is absorbing ALS ONE through a 2026 strategic integration. Closest peer in mission, scope, and integration counterpart.
- Robert Packard Center for ALS Research: Johns Hopkins-based ALS research center funding collaborative science. Comparable academic-anchored ALS research funding model.
- Project ALS: Nonprofit funding collaborative ALS research at leading academic and industry labs. Comparable research-funding model and disease-specific mission.
- Compassionate Care ALS: Massachusetts-based ALS care nonprofit that is both a partner and a peer; provides direct equipment, education, and support to people living with ALS.
- Les Turner ALS Foundation: Chicago-based ALS-specific nonprofit funding research and providing patient services. Comparable disease-specific scope, regional anchor, and care-plus-research model.
- Answer ALS Foundation: ALS research consortium producing large-scale multi-omic data for ALS therapeutics. Comparable research-grantmaking focus on a single disease.
Broad incumbents
- Muscular Dystrophy Association: Larger neuromuscular disease nonprofit funding research and care across ALS, MD, and related conditions. Broader portfolio but overlaps on ALS research and patient services.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks4 records
Key highlights5 records
Customer concentration
ALS ONE social profiles
Digital presenceALS ONE financial estimates
Financial estimateRevenue estimate
Valuation estimate
ALS ONE leadership team
Management profileNumber of profiles
Profiles4 records
ALS ONE funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ALS ONE M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ALS ONE
What does ALS ONE do?
ALS ONE is a Massachusetts-based nonprofit organization that funds ALS research and delivers care resources to individuals and families impacted by ALS. It operates through three program pillars—Research, Care, and Fundraising—bringing together leading ALS researchers, clinicians, care providers, corporate leaders, and families under a shared mission to accelerate treatment discovery, provide critical equipment and resources, and foster a connected community.
Is ALS ONE a public or private company?
ALS ONE is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was ALS ONE founded?
ALS ONE was founded in 2015. It employs 1 to 10 people.
Where is ALS ONE based?
ALS ONE is headquartered in Whitman, United States, in the North America region.
How does ALS ONE make money?
One revenue line is on record: donations and Fundraising.
Who are ALS ONE's main competitors?
Direct peers on record are ALS Therapy Development Institute, ALS Association, Target ALS, ALS Network, Robert Packard Center for ALS Research, Project ALS, Compassionate Care ALS, Les Turner ALS Foundation and Answer ALS Foundation. Muscular Dystrophy Association is listed as a broad incumbent.
Does ALS ONE have an API?
No public API is recorded for ALS ONE.
What industry is ALS ONE in?
ALS ONE's product category is Nonprofit Disease Research and Patient Care. Its primary akta.pro industry code is BPAGACAA, Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS), with a secondary code of BPAGAKAL, Health & Medical Research Grantmaking Foundations. Its NAICS code is 813212 and its SIC code is 8090.