enQuire BioReagents

What enQuire BioReagents does

enQuire BioReagents is a privately held specialty bioreagent supplier founded in 2015 and headquartered in Denver, Colorado. The company manufactures and distributes primary antibodies, recombinant proteins, isotype controls, secondary antibodies, and supporting reagents (buffers, substrates, siRNA) for biomedical research laboratories and in vitro diagnostics (IVD) assay developers. Its core technology differentiator is MS-QAVA™, a mass spectrometry-based antibody validation workflow that measures non-specific binding against thousands of proteins, with the company claiming less than 13% non-specific binding versus an industry average of over 30%. Ultraspecific antibodies are tested against more than 19,000 full-length human proteins using HuProt™ Arrays, targeting S-scores above 2.5. The company historically offered SingleStep™ Poly-HRP conjugated secondary antibodies for IHC signal amplification, though this line has been discontinued.

The business model is direct-to-consumer e-commerce through enquirebio.com, with a catalog exceeding 1,000 antibody SKUs and thousands of recombinant proteins. Pricing is unit-based and pay-as-you-go: antibodies typically range from $98-$559, isotype controls from $68-$368, recombinant proteins from $69 upward, and certain specialty SKUs up to $9,999. Customer segments are horizontal, with Research Laboratories as the primary segment (IHC, Flow Cytometry, Western Blot, Immunofluorescence use cases) and IVD manufacturers/clinical labs as a secondary segment served through GMP-grade secondary antibodies. The company ships globally with no disclosed geographic restrictions, uses SEO-optimized product pages and email registration for promotions as its marketing channels, and reports no funding rounds, M&A activity, or partnership disclosures in the available data.

Name

enQuire BioReagents

Legal name

enQuire BioReagents

Website

https://enquirebio.com

Company type

Private

Founded year

2015

Operating status

Operating

Headcount range

1–10 employees

Short description

enQuire BioReagents is a Denver-based specialty bioreagent company that supplies primary antibodies, recombinant proteins, and GMP IVD reagents to research and diagnostic assay developers through a direct global e-commerce storefront, differentiated by MS-QAVA™ mass spectrometry-based antibody validation.

Ownership category

akta.pro rank

Product category

Life Science Research Reagents (Antibodies and Recombinant Proteins)

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industry

IVD Reagents, Assay Kits & Consumables (Non-instrument) (HLAHAAAM)

Keywords

• Antibody reagents
• Recombinant proteins
• IVD reagents
• Immunohistochemistry antibodies
• Flow cytometry reagents

Headquarters

HQ city

Denver

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Supply Chain, Marketing or Sales, Infrastructure

Revenue model

1. Antibody Sales: Sale of primary antibodies for IHC and Flow Cytometry applications. Products include monoclonal antibodies validated through independent testing with MS-QAVA™ technology.
2. Recombinant Protein Sales: Sale of recombinant proteins including cytokines, growth factors, and signaling molecules. Products are tested for purity and bioactivity.
3. Support Products: GMP secondary antibodies for IVD and research, isotype controls, buffers, and substrates validated by antibody and protein experts.

Pricing tiers

Go-to-market motion2 records

Distribution channels1 record

Marketing channels3 records

Core offering

enQuire BioReagents manufactures and sells validated bioreagents — primary antibodies for IHC and Flow Cytometry, thousands of recombinant proteins, and support reagents including GMP secondary antibodies, isotype controls, buffers, substrates, and siRNA — to research and IVD assay developers. Products are differentiated by proprietary MS-QAVA™ mass-spectrometry validation and HuProt™ Array specificity screening carried out by in-house PhD researchers.

Product overview

enQuire BioReagents is a biotech reagent company specializing in antibodies and recombinant proteins for research and diagnostics. The core product portfolio consists of Primary Antibodies for immunohistochemistry (IHC) and flow cytometry, Recombinant Proteins tested for purity and bioactivity, Support Products including isotype controls and secondary antibodies, and TranslationBlocker siRNA products for gene silencing research. Additional offerings include chemiluminescent substrates. The company positions itself on quality through independent validation supported by PhD researchers, with products ranging from research-use-only antibodies to GMP-grade reagents for IVD applications.

Differentiator

Problem solved

Functional benefit

Products and services

• Primary Antibodies Monoclonal and polyclonal primary antibodies targeting various biomarkers for immunohistochemistry (IHC) and flow cytometry applications, validated and independently tested by an in-house team of PhD researchers using MS-QAVA™ mass spectrometry and HuProt™ Array specificity screening. Aimed at academic and industrial biomedical research laboratories.
• Recombinant Proteins Thousands of recombinant proteins including cytokines, growth factors, and signaling molecules from human, mouse, rat, and other species, expressed in E. coli, mammalian, yeast, and baculovirus systems and tested for purity and bioactivity. Aimed at life-science research laboratories.
• Support Products (Buffers, Substrates, Secondary Antibodies) GMP secondary antibodies for IVD and research applications, along with buffers and substrates validated by antibody and protein experts. Provides ancillary reagents used alongside primary antibodies and recombinant proteins by research and IVD laboratories.
• Isotype Controls Isotype control antibodies for flow cytometry applications, including Rat IgG1 (HRPN), Rat IgG2a (2A3), Rat IgG2b (LTF-2), Mouse IgG1 (MOPC-21), Mouse IgG2a (C1.18.4), Mouse IgG2b (MPC-11), and Armenian Hamster IgG (PIP), available in multiple conjugates.
• TranslationBlocker siRNA siRNA duplexes for gene silencing research, targeting genes such as Human PD-L1/CD274, Human BAX, Human p53, Human Amyloid beta A4 protein (APP), Human ALK tyrosine kinase receptor, and Human HIF-1 alpha. Targeted at molecular biology and cell signaling researchers.
• Femto Chemiluminescent Substrate High-sensitivity chemiluminescent substrate for Western Blot (WB) protein detection, used by research laboratories performing immunoblotting.

Quantifiable outcome

• Less than 12.9% non-specific binding for MS-QAVA™ validated antibodies versus industry average of over 30%
• +2 more outcomes

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators3 records

Recent moves5 records

Expansion highlights4 records

Direct peers

• Cell Signaling Technology: CST produces highly validated antibodies for applications including IHC, Western blot, and flow cytometry — directly overlapping enQuire's core antibody offering with a similar focus on validation rigor.
• Bethyl Laboratories: Bethyl Laboratories specializes in highly validated polyclonal antibodies for research applications, sharing enQuire's positioning around rigorous antibody validation and specificity for IHC/WB use cases.
• SouthernBiotech: SouthernBiotech manufactures secondary antibodies and isotype controls for flow cytometry and immunoassays — directly comparable to enQuire's support products including isotype controls and GMP secondary antibodies.
• Rockland Immunochemicals: Rockland Immunochemicals manufactures antibodies and antibody-based reagents for research and IVD applications — directly comparable to enQuire's GMP secondary antibody and research antibody lines.
• Proteintech: Proteintech is a direct peer selling validated antibodies and recombinant proteins with a strong e-commerce presence, comparable to enQuire's product-led growth model and antibody catalog focus.
• Abcam: Abcam is a leading global supplier of research-grade antibodies and related reagents, directly comparable to enQuire's primary antibody catalog targeting academic and industrial research laboratories.
• GenScript: GenScript supplies recombinant proteins, antibodies, and gene synthesis services for life science research — overlapping with enQuire's recombinant protein catalog and custom antibody capabilities.
• Santa Cruz Biotechnology: Santa Cruz Biotechnology is a long-standing direct competitor in research antibodies with a broad catalog serving academic researchers, overlapping enQuire's primary antibody and IHC product lines.

Broad incumbents

• Bio-Techne: Bio-Techne (parent of R&D Systems, Novus Biologicals, and Tocris) is a broad incumbent offering proteins, antibodies, and GMP reagents, with overlapping product categories to enQuire's full catalog including IVD reagent potential.
• Thermo Fisher Scientific: Thermo Fisher's Invitrogen and Pierce brands dominate the global antibody, protein, and IVD reagent markets — a broad incumbent competitor that overlaps across enQuire's entire product portfolio.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/enQuireBio
• LinkedInlinkedin.com/company/enquire-bioreagents

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about enQuire BioReagents