Endpoint Preclinical
Endpoint Preclinical is a preclinical consulting network offering integrated surgical, imaging, toxicology, and regulatory services to CROs, pharmaceutical, biotech, medical device, and academic clients. It deploys 100+ on-site specialists across 16+ service domains and provides accredited training programs.
- Company typePrivate
- Founded2023
- HeadquartersLondon, Canada
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Endpoint Preclinical does
Endpoint Preclinical (legal entity Brit Scot Holdings Inc., headquartered in Dallas, TX) operates a preclinical consulting network serving contract research organizations, pharmaceutical companies, biotechnology firms, medical device manufacturers, and academic laboratories. The company provides a single point of contact for integrated preclinical expertise spanning 16+ core service domains, including microsurgery, interventional and minimally invasive surgery, structural heart procedures, ventricular pressure-volume loop analysis, echocardiography, neurosurgery, toxicology, safety pharmacology, ECG and respiratory analysis, radiology, model development, orthopedic surgery, biostatistics, cadaver surgical services, regulatory strategy, and training. Services are delivered on-site at client facilities globally by a network of 100+ board-certified specialists, surgeons, toxicologists, radiologists, and regulatory experts. The company is led by CEO and Co-founder Cole McLarty.
The underlying technology is not a software platform but rather a curated expert network with specialized technical capabilities, including advanced telemetry implantation across DSI, EMKA, and Kaha platforms, pressure-volume loop analysis for cardiac contractility assessment, multimodality radiology interpretation (MRI, PET, SPECT, CT, ultrasound, radiography), and GLP-compliant toxicology study oversight supporting IDE, IND, NDA, PMA, and 510(k) regulatory submissions.
The business model operates through two revenue streams: (1) project-based preclinical consulting engagements (quote-based, sold through enterprise field sales and event-driven channels targeting SOT, ACT, and related conferences), and (2) published-price training programs including the Rodent PV Loop Masterclass (Academic $4,800, Industry $5,800 per participant) and On-Site Kaha Telemetry Training (starting at $4,795 USD). Distribution relies on direct on-site service delivery, conference presence, on-demand webinars, expert network referrals, and academic partnerships with the American Physiological Society and University of British Columbia Okanagan.
Endpoint Preclinical firmographics
Firmographics- Name
- Endpoint Preclinical
- Legal name
- Brit Scot Holdings Inc.
- Website
- https://endpointpreclinical.com
- Company type
- Private
- Founded year
- 2023
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Endpoint Preclinical is a preclinical consulting network offering integrated surgical, imaging, toxicology, and regulatory services to CROs, pharmaceutical, biotech, medical device, and academic clients. It deploys 100+ on-site specialists across 16+ service domains and provides accredited training programs.
- Ownership category
- akta.pro rank
Endpoint Preclinical industry classification
Industry- Product category
- Preclinical Consulting Services
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171), Other Scientific and Technical Consulting Services (54169)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Preclinical CROs (Discovery/Pharmacology/DMPK) (HLAGAAAB)
- akta.pro secondary industries
- Nonclinical Study Management & Regulatory Writing (IND-enabling) (HLAGAFAN), Data Management, Biostatistics & Statistical Programming FSP (HLAGAOAB)
Keywords
Where Endpoint Preclinical is headquartered
LocationHeadquarters
- HQ city
- London
- HQ country
- Canada
- HQ region
- North America
Offices1 record
Markets served
Endpoint Preclinical business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D
Revenue model
- Preclinical Consulting Services: Project-based consulting engagements providing expert preclinical services including surgical procedures, study design, regulatory strategy, imaging interpretation, and data analysis. Services delivered on-site at client facilities or through remote consultation.
- Training Programs: Multi-day specialized training programs including the Rodent Pressure-Volume Loop Masterclass and Qualitative ECG Training. Offered in various formats (on-site, virtual, hybrid) with tiered pricing for academic vs industry participants.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Multi-year contract | Rodent PV Loop Masterclass - Academic |
| Unit Pricing | Multi-year contract | Rodent PV Loop Masterclass - Industry |
| Unit Pricing | Pay-as-you-go | On-Site Kaha Telemetry Training |
| Other | Multi-year contract | Qualitative ECG Training for Preclinical Research |
| Other | Multi-year contract | Consulting Services |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels5 records
Endpoint Preclinical product offering
Product offeringCore offering
Endpoint Preclinical operates a centralized preclinical consulting network that delivers expert surgical, imaging, toxicology, pathology, biostatistics, and regulatory services to pharmaceutical, biotech, CRO, medical device, and academic clients. Specialists are deployed on-site at client facilities to design studies, execute surgical procedures, interpret imaging and telemetry data, and support regulatory submissions. The firm also runs multi-day training programs in microsurgery, rodent PV loops, qualitative ECG analysis, and telemetry operation.
Product overview
Endpoint Preclinical is a preclinical consulting network providing surgical, analytical, and regulatory services to CROs, pharmaceutical companies, biotech firms, medical device manufacturers, and academic labs. The company offers a comprehensive portfolio of specialized services organized around core areas: Surgical Services (microsurgery, general reconstructive surgery, interventional & minimally invasive surgery, orthopedic surgery, and cadaver services); Cardiac Services (structural heart procedures, ventricular PV loops, echocardiography, and safety pharmacology); Neurosurgery & Neurotechnology; Toxicology Services; Imaging & Diagnostics (radiology, ECG & respiratory analysis); Model Development; and Training Programs (microsurgical training, PV loop masterclasses, ECG training, and telemetry training). The company positions itself as a single point of contact simplifying preclinical research complexity, with experts performing on-site procedures directly in client laboratories. Services span from experimental design and surgical execution through data analysis, interpretation, and regulatory submission support.
Differentiator
Problem solved
Functional benefit
Products and services
- Microsurgery Services Precision microsurgical techniques for preclinical research, including microvascular anastomoses, nerve repair, intrathecal drug delivery, telemetry integration, and multi-system model development. Designed for pharmaceutical, biotech, CRO, medical device, and academic clients needing advanced surgical models.
- General & Reconstructive Surgery Broad open surgical interventions for preclinical research, including organ resection, transplantation, gastrointestinal surgery, soft tissue reconstruction, and hybrid surgical methods. Targeted at advanced preclinical research programs across CRO, pharma, biotech, device, and academic clients.
- Interventional & Minimally Invasive Surgery Catheter-based, endoscopic, and hybrid surgical interventions for preclinical studies, including transcatheter device implantation, balloon angioplasty, laparoscopic procedures, and robotic-assisted interventions used in device and therapeutic studies.
- Structural Heart Procedures Precision evaluation and intervention in preclinical cardiac models, including valve replacement and repair (TAVR, TMVR), septal defect closures, hemodynamic support, and cardiac model development for medical device and pharmaceutical clients.
- Ventricular PV Loops Pressure-Volume loop analysis providing comprehensive evaluation of cardiac contractility with both load-dependent and load-independent indices for device development and therapeutic assessment. Used by preclinical researchers evaluating cardiovascular interventions.
- Echocardiography Services Cardiovascular imaging support using portable ultrasound systems with advanced measurements including tissue Doppler imaging, speckle-tracking strain, and integrated hemodynamic analysis for therapeutic and device evaluations.
- Neurosurgery & Neurotechnology Precision surgical interventions and device evaluations across the nervous system for preclinical research, including open cranial procedures, spinal interventions, targeted drug delivery, neurovascular access, and electrophysiological mapping.
- Toxicology Services Comprehensive toxicology consulting supporting medical devices, drug-device combinations, and pharmaceuticals from feasibility through regulatory submission, including GLP/non-GLP studies, biocompatibility, E/L analysis, and risk assessment.
- ECG & Respiratory Analysis Precise evaluation of cardiac electrical activity and respiratory function with qualitative and quantitative analyses, including arrhythmia detection, heart rate variability, and S7B/E14-compliant GLP reporting for safety pharmacology studies.
- Radiology Services Expert interpretation, scoring review, analysis, and reporting of preclinical imaging data across MRI, PET, SPECT, CT, ultrasound, and radiography modalities, delivered by board-certified veterinary radiologists.
- Model Development Services Comprehensive design, optimization, and validation of preclinical disease models across cardiac, renal, pulmonary, neurological, musculoskeletal, and multi-organ systems using advanced surgical techniques.
- Orthopedic Surgery High-precision musculoskeletal interventions for preclinical research, including tendon repair, vertebral disc interventions, bone grafting, and plate/pin implantation for reproducible orthopedic studies.
- Rodent Pressure-Volume Loop Masterclass Comprehensive multi-day training program on rodent cardiac PV loops combining lectures with hands-on laboratory training, taught by Dr. Chris West and Dr. Oliver Wearing at the University of British Columbia Okanagan.
- Qualitative ECG Training for Preclinical Research Four-day course in foundations of qualitative ECG analysis covering comparative electrophysiology, species-specific data, and applied case review, led by Dr. Stacy Hosking. Offered on-site, virtually, and in hybrid formats.
- On-Site Kaha Telemetry Training Customized hands-on telemetry training for Kaha Sciences and ADInstruments users, covering arterial cannulation, pressure catheterization, and data collection strategies, with one-day and two-day formats starting at $4,795 USD.
- Multimodal Biostatistics Statistical analysis across cardiovascular, pulmonary, and neurological applications using SAS, Prism, and other platforms for individual and integrated multimodal preclinical datasets.
- Cadaver Surgical Services Ex vivo surgical simulations and device evaluations on cadaver models for procedural simulation, technique refinement, device evaluation, and hands-on surgical training in preclinical research.
- Safety Pharmacology Evaluation of cardiovascular, respiratory, and CNS functional endpoints with advanced telemetry, core battery assessment, integrated respiratory analysis, and GLP-compliant reporting for safety pharmacology studies.
- Training Services Expert training programs delivered on-site, remotely, or through specialized multi-day sessions covering surgical techniques, imaging modalities, data interpretation, and regulatory compliance for preclinical teams.
Quantifiable outcome
- Reduced study variability through expert-driven execution and standardized protocols
- +2 more outcomes
Companies that use Endpoint Preclinical
Customer profileNamed customers5 records
Segments5 records
Ideal customer profiles5 records
Endpoint Preclinical technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
Endpoint Preclinical partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core.
- American Physiological Society (APS)coreAPS partners with Endpoint Preclinical to create and support training programs, enabling professionals to expand skills, advance their careers, and foster the future of basic and translational research. The Rodent PV Loop Masterclass is recognized by APS.
- University of British Columbia OkanagancoreHost institution for the Rodent Pressure-Volume Loop Masterclass, held at the Translational Integrative Physiology Laboratory at UBC Okanagan's Reichwald Health Sciences Centre in Kelowna, BC, Canada.
Scale indicators4 records
Recent moves6 records
Expansion highlights5 records
Endpoint Preclinical competitors and assessment
Company assessmentBroad incumbents
- Eurofins Discovery: Part of Eurofins Scientific, offering preclinical drug discovery, in vitro toxicology, and safety pharmacology services. Competes for pharma/biotech preclinical services budget, particularly in regulatory toxicology and safety assessment packages.
- Fortrea: Clinical and preclinical CRO (formerly Labcorp Drug Development) offering toxicology, bioanalytical, and safety pharmacology services. Comparable as a large preclinical services competitor with established pharma relationships and GLP infrastructure.
- WuXi AppTec: Global CRO/CDMO with extensive preclinical toxicology, DMPK, and safety pharmacology capabilities. Competes for the same pharmaceutical preclinical services spend, particularly among biotech sponsors seeking integrated IND-enabling packages.
- Citoxlab (now part of Charles River): Preclinical CRO (acquired by Charles River) with deep expertise in toxicology, safety pharmacology, and surgical models across European and North American markets. Comparable as a competitor in the same preclinical services space, especially for European-headquartered pharma clients.
- Inotiv: Established preclinical CRO offering toxicology, pathology, and surgical services across research models. Comparable as a direct competitor in the preclinical CRO space, though Inotiv operates owned vivaria and a much larger full-time employee base than Endpoint's consulting network model.
- Charles River Laboratories: Largest global preclinical CRO offering discovery, safety assessment, and surgical services to pharma and biotech. Competitor in preclinical toxicology and surgical model development, but with substantially broader infrastructure and full-service delivery rather than a specialist consulting network.
Direct peers
- ToxStrategies: Scientific and regulatory consulting firm providing toxicology, risk assessment, and regulatory strategy support to pharmaceutical, chemical, and medical device companies. Closely comparable to Endpoint Preclinical in its consulting-network model and focus on nonclinical study management and regulatory submission support.
- Seventh Wave Laboratories: Preclinical CRO specializing in cardiovascular, metabolic, and renal safety pharmacology with surgical model expertise. Closely aligned with Endpoint's cardiac, telemetry, and safety pharmacology focus, serving similar pharma/biotech clients in early-stage drug development.
- Absorption Systems: Preclinical CRO specializing in ADME, pharmacokinetics, and drug-device combination testing. Comparable as a specialized preclinical services provider serving pharma and biotech, though Endpoint's network model and on-site surgical focus differ from Absorption's lab-centric delivery.
- Halloran Consulting Group: Life sciences consulting firm advising biopharma on regulatory strategy, clinical development, and quality. Comparable as a scientific/regulatory consulting partner for emerging biotech, though Halloran focuses more on clinical/CMC strategy than preclinical execution.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks5 records
Key highlights6 records
Customer concentration
Endpoint Preclinical social profiles
Digital presenceEndpoint Preclinical financial estimates
Financial estimateRevenue estimate
Valuation estimate
Endpoint Preclinical leadership team
Management profileNumber of profiles
Profiles1 record
Endpoint Preclinical funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Endpoint Preclinical M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Endpoint Preclinical
What does Endpoint Preclinical do?
Endpoint Preclinical operates a centralized preclinical consulting network that delivers expert surgical, imaging, toxicology, pathology, biostatistics, and regulatory services to pharmaceutical, biotech, CRO, medical device, and academic clients. Specialists are deployed on-site at client facilities to design studies, execute surgical procedures, interpret imaging and telemetry data, and support regulatory submissions. The firm also runs multi-day training programs in microsurgery, rodent PV loops, qualitative ECG analysis, and telemetry operation.
Is Endpoint Preclinical a public or private company?
Endpoint Preclinical is a private company. It is classified as unknown and is currently operating.
When was Endpoint Preclinical founded?
Endpoint Preclinical was founded in 2023. It employs 11 to 50 people.
Where is Endpoint Preclinical based?
Endpoint Preclinical is headquartered in London, Canada, in the North America region.
How does Endpoint Preclinical make money?
Two revenue lines are on record. Preclinical Consulting Services are the primary driver. The others are training Programs.
Who are Endpoint Preclinical's main competitors?
Broad incumbents on record are Eurofins Discovery, Fortrea, WuXi AppTec, Citoxlab (now part of Charles River), Inotiv and Charles River Laboratories. Direct peers are ToxStrategies, Seventh Wave Laboratories, Absorption Systems and Halloran Consulting Group.
Does Endpoint Preclinical have an API?
No public API is recorded for Endpoint Preclinical.
What industry is Endpoint Preclinical in?
Endpoint Preclinical's product category is Preclinical Consulting Services. Its primary akta.pro industry code is HLAGAAAB, Preclinical CROs (Discovery/Pharmacology/DMPK), with a secondary code of HLAGAFAN, Nonclinical Study Management & Regulatory Writing (IND-enabling). Its NAICS code is 541714 and its SIC code is 8731.