RESILIÉLLE COSMETICS LLC

What RESILIÉLLE COSMETICS LLC does

RESILIÉLLE COSMETICS LLC is a privately held regenerative aesthetics company founded in 2020 and headquartered in Rochester, New York. The company develops and sells Age Zero Exosomes, a topical serum line derived from Wharton's jelly of human umbilical cord stem cells, offered in three potency tiers (10 billion, 50 billion, and 100 billion exosomes per vial) alongside the NanoMist SES clinical-grade delivery device and a bundled Protocol Kit. Manufacturing takes place at an FDA-registered, New York-licensed Tissue Bank facility operating under GMP and ISO-aligned quality systems, with third-party CLIA-certified sterility, endotoxin, mycoplasma, and infectious disease testing on every lot.

The company's core technology is built around a low-passage (≤4 passages) stem cell expansion process, cryopreserved (non-lyophilized) exosome integrity validated at Harvard Labs using TEM, Immunogold, and CD63 markers, and a patent-pending manufacturing method. Products are positioned for clinical professionals, MedSpas, dermatology practices, and aesthetic clinics that integrate Age Zero into procedures such as microneedling, RF microneedling, laser and IPL treatments, chemical peels, and hair restoration to enhance patient outcomes and accelerate post-procedure recovery.

RESILIÉLLE operates a hybrid B2B go-to-market model: account-activated direct e-commerce (UPS Next Day Air with dry ice), a certified Exosome Educator sales representative network that provides in-person protocol and staff training, and an international distributor program for markets outside the United States. Revenue mechanics are predominantly unit-pricing on multi-vial boxes ($1,410 to $4,200) plus volume-based and country-tiered distributor pricing, with an Age Zero Membership Club offering contracted shipments at significant discounts. The company has earned media coverage in Vogue, The Cut, and the Journal of Cosmetic Dermatology, and is registered with the FDA under MoCRA.

Name

RESILIÉLLE COSMETICS LLC

Legal name

RESILIÉLLE COSMETICS LLC

Website

https://resilielle.com

Company type

Private

Founded year

2020

Operating status

Operating

Headcount range

11–50 employees

Short description

RESILIÉLLE COSMETICS LLC is a Rochester, NY-based regenerative aesthetics company founded in 2020 that develops and sells Age Zero Exosome topical serums, derived from Wharton's jelly of human umbilical cord stem cells, to clinical professionals, MedSpas, and aesthetic clinics for use alongside energy-based and microneedling treatments.

Ownership category

akta.pro rank

Product category

Regenerative Aesthetics / Topical Exosome Cosmetics

NAICS

Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Stem Cell–Based Regenerative Therapies (HLAAAGAA)

akta.pro secondary industries

Anti-Aging & Firming Treatments (HSALADAC), Regenerative Immunology & Inflammation Modulation (pro-regenerative biologics) (HLAAAGAL)

Keywords

• Exosome skincare serums
• Regenerative aesthetics
• Topical cosmetic serums
• Stem cell exosome therapy
• Clinical aesthetic products

Headquarters

HQ city

Rochester

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Operations, Personnel, Marketing or Sales, Infrastructure

Revenue model

1. Exosome Product Sales: RESILIÉLLE generates revenue through direct sales of Age Zero Exosome products to clinical professionals, MedSpas, and aesthetic clinics. Products are sold in various concentrations (10B, 50B, 100B exosomes) with different vial sizes and quantities. Orders are placed online through accounts with activation support from sales representatives. The company also offers an Age Zero Membership Club providing contracted shipments at significant discounts.
2. Volume and Distributor Pricing: Discounts are available based on annual volume and the size of the country for international distributors. Large volume purchases qualify for additional savings.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

RESILIÉLLE develops and manufactures Age Zero Exosomes — topically applied, cryopreserved exosome serums derived from Wharton's Jelly of human umbilical cord stem cells, sold in three potency tiers (10B, 50B, 100B exosomes) directly to clinical professionals, MedSpas, and aesthetic clinics for use in regenerative skin and scalp treatments. The company also offers the NanoMist SES delivery device and bundled Protocol Kits as part of its professional regenerative aesthetics platform.

Product overview

RESILIÉLLE COSMETICS LLC offers the Age Zero™ Exosome platform — a portfolio of topically applied, cryopreserved exosome serums derived from Wharton’s Jelly of human umbilical cord stem cells. The core product line consists of three potency tiers (10 Billion, 50 Billion, and 100 Billion exosomes) sold in multi-vial boxes, along with an optional Protocol Kit that bundles the serums with the NanoMist SES™ clinical-grade delivery device, rack cards, and digital protocol materials. All products are manufactured in the company’s FDA-registered, ISO cleanroom facility in New York and are shipped frozen on dry ice.

Differentiator

Problem solved

Functional benefit

Brands

• Age Zero™: Flagship exosome product platform including Age Zero Exosomes serum derived from Wharton’s Jelly stem cells for topical skincare applications.

Products and services

• Age Zero Exosomes Topically applied exosome serum derived from Wharton's Jelly of human umbilical cord stem cells, suspended in sterile saline, used to restore skin firmness and texture, reduce recovery time, and enhance rejuvenating effects of aesthetic treatments.
• Resiliélle 10 Billion Exosomes, 5mL Multi-use 10 billion exosome vials in 5mL format for daily use and a wide range of procedures; available in 6-vial or 9-vial boxes at $1,410.00 per box, providing up to 18 facial treatments per 9-vial box.
• Resiliélle 50 Billion Exosomes, 5mL 50 billion exosome vials in 5mL format, sold in 6-vial boxes at $4,200.00 per box; intended for facial and hair restoration treatments.
• Resiliélle 100 Billion Exosomes, 2.5mL 100 billion exosome vials in 2.5mL format, sold in 3-vial boxes at $4,200.00 per box; the highest potency offering in the Age Zero line.
• Resiliélle Age Zero™ Protocol Kit Bundled launch kit for clinics combining 9 vials of 10B/5mL exosomes, 1 vial of 50B/5mL exosomes, the Resiliélle NanoMist SES™ clinical-grade delivery device, 10 office rack cards, digital brochures, and a digital protocol book; sold at $2,190.00 per kit.

Quantifiable outcome

• 88% of patients reported noticeable improvement in skin firmness
• +2 more outcomes

Named customers3 records

Segments2 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• ExoCoBio: ExoCoBio is a Korean-origin exosome biotechnology company with global aesthetic distribution (including its EXOBIO and post-procedure exosome serums), offering a directly comparable stem-cell-derived exosome skincare product set aimed at clinics and consumers.
• AnteAGE: AnteAGE (by Cellese) sells stem cell growth factor and exosome-based professional skincare serums and microneedling solutions to MedSpas and dermatology practices, overlapping with RESILIÉLLE on regenerative aesthetics positioning and clinician channel.
• Kimera Labs: Kimera Labs is a US manufacturer of mesenchymal stem cell-derived exosome products for clinical and aesthetic use, positioning in the same exosome-for-skin/hair professional channel as RESILIÉLLE and competing on purity, source material, and lot-level testing.
• BENEV: BENEV is a US-based medical aesthetics company selling exosome-based regenerative complex products (e.g., Exosome Regenerative Complex) to clinics and MedSpas for skin and hair rejuvenation, directly competing with RESILIÉLLE's Age Zero platform in the professional exosome aesthetics channel.
• Rion Aesthetics (Plated Skin Science): Rion Aesthetics (Plated Skin Science) sells platelet-derived growth factor/exosome serums for in-office and daily-use skin rejuvenation, competing with RESILIÉLLE in the regenerative aesthetics professional channel with similar claims around post-procedure recovery and skin quality.
• Calecim (Cellese): Calecim, from Cellese, markets stem cell-conditioned media-derived skincare products to aesthetic clinics for skin rejuvenation and post-procedure recovery, sharing RESILIÉLLE's regenerative biologics approach and professional-channel sales motion.

Broad incumbents

• SkinMedica (Allergan Aesthetics): SkinMedica, part of Allergan Aesthetics, is an established physician-dispensed skincare brand spanning anti-aging, post-procedure, and rejuvenation lines. It serves the same clinical professional channel as RESILIÉLLE but with a much broader, non-exosome product portfolio.
• Galderma (aesthetic and skincare portfolio): Galderma is a global dermatology and aesthetics company with a broad portfolio spanning injectable aesthetics, therapeutic dermatology, and skincare. It competes indirectly via its aesthetics-adjacent skincare and post-procedure offerings that overlap with regenerative aesthetics adjacencies RESILIÉLLE targets.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks7 records

Key highlights7 records

Customer concentration

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about RESILIÉLLE COSMETICS LLC