Orsini
Orsini is a privately held, independent U.S. specialty pharmacy founded in 1987 providing rare disease and gene therapy pharmacy solutions. It serves biopharma manufacturers, prescribers, payors, and patients across all 50 states via specialty dispensing, a patient services hub, 3PL logistics, home infusion, and the ORBIT analytics platform.
- Company typePrivate
- Founded1987
- HeadquartersElk Grove Village, United States
- Headcount—
- GTM typeB2B and B2C
- OfferingServices
What Orsini does
Orsini is a privately held, independent U.S. specialty pharmacy founded in 1987, headquartered in Elk Grove Village, Illinois, with a second fully redundant facility in Columbus, Ohio launched in October 2025. The company focuses exclusively on rare disease and gene therapy pharmacy solutions, organizing its operations around 15 Therapeutic Centers of Excellence (including Cell & Gene Therapy, Allergy & Immunology, Cardiology, Genetics, Neurology, Hematology, and Pulmonology) and dedicated Therapy Care Teams. Orsini's product surface spans specialty pharmacy dispensing, a Patient Services Hub, Third-Party Logistics (3PL, operated in partnership with Presa Solutions), and a nationwide Home Infusion & Nursing network. The differentiator is ORBIT (Orsini Rare Business Intelligence Technology), an AI-enabled, API-first analytics and real-world data platform that exchanges data with manufacturers, patient engagement systems, and partners such as PicnicHealth.
The business is enterprise-anchored: Orsini signs exclusive or limited-distribution agreements with biopharma manufacturers for high-cost, complex specialty drugs and gene therapies (12+ FDA-approved gene therapies, including Zolgensma, Elevidys, Casgevy, Hemgenix, LYFGENIA, ZYNTEGLO, and SKYSONA) and earns revenue from dispensing fees/margins, managed-services fees for hub/3PL, and home infusion nursing services. Go-to-market is sales-led, targeting biopharma manufacturers for commercialization partnerships, prescribers for referrals, and payors for access. The customer base includes major manufacturers such as Gilead, Roche/Genentech, Ionis, KalVista, Crinetics, Cytokinetics, Zevra, Glaukos, Immedica, Genetix, and Denali. Orsini is licensed and accredited across URAC (including Rare Disease Pharmacy Center of Excellence), ACHC (with Distinction in Rare Diseases and Orphan Drugs), NABP, the Joint Commission, and Legitscript, and serves patients in all 50 states and Puerto Rico.
Orsini firmographics
Firmographics- Name
- Orsini
- Legal name
- Orsini
- Website
- https://orsini.com
- Company type
- Private
- Founded year
- 1987
- Operating status
- Operating
- Short description
- Orsini is a privately held, independent U.S. specialty pharmacy founded in 1987 providing rare disease and gene therapy pharmacy solutions. It serves biopharma manufacturers, prescribers, payors, and patients across all 50 states via specialty dispensing, a patient services hub, 3PL logistics, home infusion, and the ORBIT analytics platform.
- Ownership category
- akta.pro rank
Orsini industry classification
Industry- Product category
- Specialty Pharmacy Services
- NAICS
- Ambulatory Health Care Services (621), Other Ambulatory Health Care Services (6219)
- SIC
- Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047), Services-Nursing & Personal Care Facilities (8050)
- akta.pro primary industry
- Specialty Pharmacy & Complex Therapy Management Platforms (HLACAKAG)
- akta.pro secondary industry
- Medication Pricing, Copay Assistance & Patient Financial Support Tools (HLACAKAN)
Keywords
Where Orsini is headquartered
LocationHeadquarters
- HQ city
- Elk Grove Village
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
Orsini business model
Business model- GTM type
- B2B and B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Specialty Pharmacy Dispensing: Orsini dispenses high-cost, high-complexity specialty pharmaceuticals for rare disease patients. Services include pharmacy distribution, clinical management, reimbursement support, and direct delivery to home or site of administration. Revenue is generated through dispensing fees and margins on specialty medications.
- Patient Services Hub: Integrated hub services for biopharma manufacturers including patient services, benefits verification, financial assistance enrollment, clinical education, nurse coordination, and data services. Provides a single point of contact between manufacturers and patients.
- Third-Party Logistics (3PL): 3PL services to biopharma manufacturers as part of full-service commercialization solutions. Includes supply chain management, inventory control, and logistics coordination from facilities in Illinois and Ohio.
- Home Infusion & Nursing Services: Home infusion services through a nationwide nursing network, with nurse managers overseeing the network. Revenue generated through nursing visit fees and infusion service coordination.
Go-to-market motion3 records
Distribution channels5 records
Marketing channels5 records
Orsini product offering
Product offeringCore offering
Orsini is a nationwide specialty pharmacy that dispenses high-cost, high-complexity medications for rare disease and gene therapy patients, with direct-to-patient delivery, home infusion nursing, and patient support services. It also provides biopharma manufacturers with Patient Services Hub, third-party logistics (3PL), and the ORBIT AI-enabled analytics platform for real-world data and program management.
Product overview
Orsini is a nationwide specialty pharmacy providing integrated rare disease pharmacy solutions with a high-touch care model centered on experienced Therapy Care Teams. The core offering combines specialty pharmacy services with a Patient Services Hub, Third-Party Logistics (3PL), and Home Infusion & Nursing. Central to the platform is ORBIT (Orsini Rare Business Intelligence Technology), an AI-enabled analytics platform that uses an API-forward approach for real-time data exchange with manufacturers and partners. The company organizes services through Therapeutic Centers of Excellence across 15+ specialty areas including Allergy & Immunology, Cardiology, Cell & Gene Therapy, Endocrinology, Genetics, Hematology, Neurology, and Pulmonology. Services are delivered from headquarters in Elk Grove Village, IL and a fully redundant Columbus, OH facility.
Differentiator
Problem solved
Functional benefit
Products and services
- Specialty Pharmacy Services Nationwide specialty pharmacy focused on rare disease patients, providing high-touch, customized dispensing and clinical management from dedicated Therapy Care Teams throughout the treatment journey. Services include prescription processing, benefits investigation, prior authorization support, free overnight delivery, and 24/7 pharmacist access across all 50 states and Puerto Rico.
- Patient Services Hub Integrated patient services hub acting as single point of contact between biopharma manufacturers and patients. Offers benefits verification, patient education, clinical education, adherence calls, financial assistance enrollment, and customized data and insights for manufacturer clients.
- Third-Party Logistics (3PL) 3PL services for biopharma manufacturers with a single point of contact and dedicated subject matter experts, providing supply chain management, inventory control, and logistics. Managed from the Illinois headquarters and the fully redundant Columbus, Ohio facility, powered by Presa Solutions, and includes ultra-cold storage capabilities for gene therapies.
- Home Infusion and Nursing Nationwide home infusion services through a comprehensive nursing network of highly skilled RNs providing disease- and therapy-specific training, in-home infusions, therapy self-administration training, and nurse support hotline. Coordinated through Orsini nurse managers for seamless care delivery.
- ORBIT Technology Platform AI-enabled reporting and analytics platform that leverages real-world data collection with robust analytics to help pharmaceutical manufacturers better understand and address the unique needs of rare disease patients. Uses an API-forward approach for real-time data exchange with pharmacies, patient engagement platforms, and manufacturers' systems, and includes the ORBIT Track feature for partner collaboration and patient case management.
Quantifiable outcome
- Average time to fill: 4 days for pharmacy benefit dispenses, 10 days for medical benefit dispenses
- +3 more outcomes
Companies that use Orsini
Customer profileNamed customers11 records
Segments4 records
Ideal customer profiles4 records
Orsini technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
Integration2 records
AI capability3 records
Feature3 records
Orsini partnerships and signals
Strategic signalScale indicators7 records
Recent moves7 records
Expansion highlights5 records
Orsini competitors and assessment
Company assessmentDirect peers
- Amber Specialty Pharmacy: Amber Specialty Pharmacy (Hy-Vee subsidiary) operates a specialty pharmacy focused on complex patient populations including rare diseases, transplants, and oncology with embedded hub services. Closely aligned with Orsini on specialty dispensing plus integrated hub model.
- Soleo Health: Soleo Health provides specialty home infusion and pharmacy services for patients with complex chronic and rare conditions, including gene therapies. Closely comparable to Orsini's home infusion & nursing network for high-cost specialty biologics.
- PantherRx Rare: PantherRx Rare is a specialty pharmacy dedicated to rare and orphan disease therapies, providing dispensing, hub, and clinical management. A direct competitor to Orsini in rare disease specialty distribution with similar independence positioning.
- Biologics by McKesson: Biologics by McKesson is an independently operated specialty pharmacy focused on oncology, rare disease, and chronic complex conditions, providing dispensing and patient support services. Closely comparable to Orsini in business model, though Biologics leans more oncology, while Orsini leans rare/gene therapy.
Regional players
- Onco360 Oncology Pharmacy: Onco360 is one of the largest independent specialty pharmacies focused on oncology, with select rare disease coverage. Indirect peer to Orsini due to overlapping specialty drug distribution and hub services, but more concentrated in oncology rather than rare/gene therapy.
Broad incumbents
- US Bioservices (AmerisourceBergen): US Bioservices, part of AmerisourceBergen / Cencora, provides specialty pharmacy and patient support services for chronic and rare conditions. Comparable to Orsini's hub and specialty dispensing for rare disease therapies, with broader distribution scale.
- Diplomat Specialty Pharmacy (now Optum): Diplomat was an independent specialty pharmacy leader in rare disease before being acquired by UnitedHealth/Optum. Provides relevant historical and structural comparability for Orsini's rare disease niche, even as it has been folded into a payor-aligned platform.
- CVS Specialty: CVS Specialty, part of CVS Health/Caremark, dispenses high-cost specialty and rare disease therapies and provides patient hub services. Operates as a direct competitor to Orsini in rare disease distribution and hub services, with stronger payor integration but less focus as an independent specialist.
- Accredo (Express Scripts specialty pharmacy): Accredo is one of the largest specialty pharmacies in the US, dispatching high-cost and rare disease therapies via its Evernorth-backed distribution network. Directly comparable to Orsini on specialty distribution and hub services for rare disease, though at meaningfully greater scale and with a payor-aligned ownership structure.
- Walgreens Specialty Pharmacy: Walgreens Specialty Pharmacy (now part of Shields Health Solutions under Walgreens-owned specialty strategy) dispenses specialty and rare disease therapies and offers hub/adherence support. A direct broad peer to Orsini with national reach and access to specialty infusion.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Orsini social profiles
Digital presenceOrsini compliance and trust
Trust signalCompliance4 records
Orsini financial estimates
Financial estimateRevenue estimate
Valuation estimate
Orsini leadership team
Management profileNumber of profiles
Profiles9 records
Orsini funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Orsini M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Orsini
What does Orsini do?
Orsini is a nationwide specialty pharmacy that dispenses high-cost, high-complexity medications for rare disease and gene therapy patients, with direct-to-patient delivery, home infusion nursing, and patient support services. It also provides biopharma manufacturers with Patient Services Hub, third-party logistics (3PL), and the ORBIT AI-enabled analytics platform for real-world data and program management.
Is Orsini a public or private company?
Orsini is a private company. It is classified as management employee owned and is currently operating.
When was Orsini founded?
Orsini was founded in 1987.
Where is Orsini based?
Orsini is headquartered in Elk Grove Village, United States, in the North America region.
How does Orsini make money?
Four revenue lines are on record. Specialty Pharmacy Dispensing is the primary driver. The others are patient Services Hub, third-Party Logistics (3PL) and home Infusion & Nursing Services.
Who are Orsini's main competitors?
Direct peers on record are Amber Specialty Pharmacy, Soleo Health, PantherRx Rare and Biologics by McKesson. Onco360 Oncology Pharmacy is listed as a regional player. Broad incumbents are US Bioservices (AmerisourceBergen), Diplomat Specialty Pharmacy (now Optum), CVS Specialty, Accredo (Express Scripts specialty pharmacy) and Walgreens Specialty Pharmacy.
Does Orsini have an API?
Yes. ORBIT (Orsini Rare Business Intelligence Technology) uses an API-forward approach to exchange real-time data with pharmacies, patient engagement platforms, manufacturers' systems, and other business associates.
What industry is Orsini in?
Orsini's product category is Specialty Pharmacy Services. Its primary akta.pro industry code is HLACAKAG, Specialty Pharmacy & Complex Therapy Management Platforms, with a secondary code of HLACAKAN, Medication Pricing, Copay Assistance & Patient Financial Support Tools. Its NAICS code is 621 and its SIC code is 5047.