The Institute For Neurodegenerative Diseases (ind)

What The Institute For Neurodegenerative Diseases (ind) does

The Institute for Neurodegenerative Diseases (IND) of Florida is a 501(c)(3) non-profit research organization operating under the Parkinson's & Alzheimer's Research and Education Foundation (PAREF), founded in 2004 and headquartered in Boca Raton, Florida. IND focuses on the prevention and treatment of neurodegenerative diseases — specifically Alzheimer's disease, Parkinson's disease, Lewy Body Dementia, and Frontotemporal Dementia — serving at-risk individuals, patients already diagnosed, their caregivers, and the broader community.

IND's technical core is a multi-marker blood-based biomarker testing program that measures more than 120 novel brain proteins, including Amyloid beta 40/42 and phosphorylated tau 217/181, to assess neurodegenerative disease risk and track intervention effectiveness. The program is operationalized through the Biorepository Study (over 100 individuals contributing samples) and a longitudinal study that has enrolled 400 participants. IND also uses N-of-1 observational trials that evaluate interventions using the individual as the sole unit of observation, with biomarker tracking as the outcome measure. Beyond the laboratory, IND delivers free online brain health courses (women's brain health, exercise, nutrition), in-person wellness classes at the Parkinson's Wellness Center in Boca Raton, patient and caregiver support groups, and quarterly educational symposia across Florida, New York, and California. Initial research findings on 75 participants were presented at the 2024 American Academy of Neurology Meeting and the 2024 Alzheimer's Association International Conference.

IND's revenue model is donation-based, with the Altman Family contributing over $1 million since 2015 and the Memories for Mary campaign (David and Kathy Twardock) raising over $500,000, supplemented by individual donors at tiered levels ($25–$1,000), named scholarships (Dr. Manfred Muenter Summer Scholarship), employee matching, and student-run fundraisers (Aces for Alzheimer's). All community programs are provided free of charge. The organization is led by Dr. Richard S. Isaacson (Director of Research, Harvard-trained) and Dr. Stuart H. Isaacson (Physician Researcher, Best Doctors in America), with Stanley Prusiner listed as a founding director, and is supported by an interdisciplinary team of clinicians, researchers, biostatisticians, and operations staff.

Name

The Institute For Neurodegenerative Diseases (ind)

Legal name

Parkinson's Research and Education Foundation

Website

https://ind.org

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

1–10 employees

Short description

The Institute for Neurodegenerative Diseases (IND) is a non-profit research organization developing multi-marker blood-based biomarker tests and delivering free community education for the prevention of Alzheimer's, Parkinson's, and related neurodegenerative diseases.

Ownership category

akta.pro rank

Product category

Neurodegenerative Disease Research and Education

NAICS

Voluntary Health Organizations (813212), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Cognitive & Behavioral Neurology (Dementia/Memory Disorders) (HLAKAIAH)

akta.pro secondary industry

Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS) (BPAGACAA)

Keywords

• Neurodegenerative disease research
• Alzheimer's prevention clinic
• Parkinson's disease research
• Blood biomarker testing
• Brain health education

Headquarters

HQ city

Boca Raton

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Donations and Charitable Contributions: IND's non-profit parent organization, Parkinson's & Alzheimer's Research and Education Foundation (PAREF), is a 501(c)(3) charitable organization (EIN: 20-0888895) that accepts donations at various levels ($25, $50, $100, $500, $1000) via PayPal, check, donor advised funds, employee matching, stock, or planned gifts.
2. Named Scholarships and Research Grants: IND receives funding through named scholarships such as the Dr. Manfred Muenter Summer Scholarship, as well as support from major donors including the Altman Family (over $1,000,000 since 2015) and the Memories for Mary campaign (over $500,000).

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels7 records

Core offering

IND conducts clinical research on neurodegenerative disease biomarkers using proprietary multi-marker blood-based biomarker panels measuring over 120 brain proteins in its Boca Raton laboratory, and operates the Biorepository Study for Neurodegenerative Diseases enrolling over 100 participants. It also delivers free educational courses (women's brain health, exercise and movement, brain healthy foods), in-person wellness classes at the Parkinson's Wellness Center, patient and caregiver support groups, and quarterly educational symposia in Florida, New York, and California. All community-facing programs are provided free of charge, funded by charitable donations to the parent 501(c)(3) PAREF foundation.

Product overview

The Institute for Neurodegenerative Diseases of Florida (IND) operates as a nonprofit research organization offering a combination of clinical research services and free educational resources. Its core offerings include multi-marker blood biomarker testing panels for detecting neurodegenerative disease risk, supported by the Biorepository Study. Complementing this are free online educational courses covering women's brain health, exercise and movement, and nutrition, along with in-person wellness classes at the Parkinson's Wellness Center, support groups, and quarterly educational symposiums. The organization does not operate a unified software product but rather provides research programs and educational content aimed at preventing and treating Alzheimer's, Parkinson's, and Lewy Body Dementia.

Differentiator

Problem solved

Functional benefit

Brands

• Parkinson's Wellness Center: A wellness center in Boca Raton, Florida offering daily classes, support groups, and resources free of charge to the community, including guided exercises, activities, and techniques that facilitate movement, promote mindfulness, and strengthen memory.

Products and services

• Multi-Marker Blood Biomarker Panels

Quantifiable outcome

• Up to 40% of Alzheimer's disease cases may be preventable based on modifiable risk factors (2020 Lancet Commission Report)
• +1 more outcomes

Named customers1 record

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Banner Alzheimer's Institute: Nonprofit research and clinical care organization focused on Alzheimer's prevention and treatment. Comparable to IND's prevention-clinic, blood-biomarker, and translational research model in a similar non-academic non-profit setting.
• Alzheimer's Association: The largest U.S. nonprofit focused on Alzheimer's care, support, and research. Highly comparable to IND's disease-specific non-profit model for AD, with overlapping education, research funding, and community support programs at much larger national scale.
• Michael J. Fox Foundation for Parkinson's Research: Nonprofit funding Parkinson's research and biomarker initiatives. Directly comparable to IND on disease-specific (PD) research funding, patient engagement, and clinical-trial enablement, and IND's Dr. Stuart Isaacson has worked with the foundation.
• UsAgainstAlzheimer's: Patient-advocacy and policy nonprofit focused on Alzheimer's prevention and treatment. Comparable to IND in the nonprofit, prevention-focused, advocacy-aligned space targeting AD risk reduction and research.
• Lewy Body Dementia Association: Nonprofit dedicated to Lewy Body Dementia awareness, support, and research. Directly comparable on the disease-specific community, education, and research support mission that IND also pursues for LBD.
• Fisher Center for Alzheimer's Research at Rockefeller University: Nonprofit research program producing Alzheimer's basic and translational research. Comparable to IND on the nonprofit-driven neurodegenerative research and education axis, though anchored to a university rather than a community clinic.

Broad incumbents

• Mayo Clinic Alzheimer's Disease Research Center: NIA-funded academic research center running longitudinal biomarker studies and clinical trials. Comparable to IND's biorepository and longitudinal AD research model but at far greater scale within an academic medical center.
• Cleveland Clinic Lou Ruvo Center for Brain Health: Hospital-affiliated center delivering clinical care, research, and education across neurodegenerative diseases. Comparable to IND on combining clinical research with community education, but operates within a much larger health system.

Emerging players

• Quanterix: Commercial ultra-sensitive biomarker detection platform used in neurodegeneration and other disease research. Comparable as an enabling/competing technology player in the blood-based biomarker space IND is pursuing.
• C2N Diagnostics: Commercial diagnostics company offering the PrecivityAD blood test for amyloid pathology. Closest commercial comparator to IND's biomarker panel work, directly addressing IND's primary technology axis with a marketed product.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/people/The-Institute-for-Neurodegenerative-Diseases-IND/61578054517410
• LinkedInlinkedin.com/company/the-institute-for-neurodegenerative-diseases

Revenue estimate

Valuation estimate

Number of profiles

Profiles17 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about The Institute For Neurodegenerative Diseases (ind)