The Science Behind
The Science Behind is a Cardiff-based specialist clinical research services provider that integrates non-invasive neurostimulation (TMS), EEG, and Quantitative Sensory Testing into Phase I CNS drug trials for biotech, pharma, and CRO clients.
- Company typePrivate
- Founded2016
- HeadquartersCardiff, United Kingdom
- Headcount1–10
- GTM typeB2B
- OfferingServices
What The Science Behind does
The Science Behind is a Cardiff, UK-based specialist clinical research services provider focused on Phase I (early-phase) clinical trials for central nervous system (CNS) drug candidates. It operates as a trading division of Brainbox Ltd (registered in England and Wales, company number 07288205) and was established in 2016. Its core offer is a portfolio of non-invasive neurostimulation and neuroimaging service modules — Pharmaco-TMS (Transcranial Magnetic Stimulation including TMS-EDMs and Threshold Tracking Paired Pulse protocols), Pharmaco-EEG (32-channel qEEG with 10-20 electrode placement and auditory habituation paradigms), Cognitive and Physiological Assessments, and Quantitative Sensory Testing (static and dynamic somatosensory protocols such as temporal summation and conditioned pain modulation). These modalities are offered standalone or in integrated multimodal combinations, including TMS-EEG, to capture both motor and non-motor cortical regions and deliver objective, quantifiable pharmacodynamic readouts in early-phase CNS studies.
The firm delivers these services through a turnkey, study-by-study professional services model, supplying protocol design, equipment, trained EEG and TMS technicians, site training, data collection, quality control, and analysis, which removes the need for clients to make capital investment in specialised neuroscience infrastructure. Customers are CNS-focused pharmaceutical and biotechnology sponsors (e.g., Synendos Therapeutics on SYT-510; Autifony Therapeutics on AUT00201 in MEAK) and Contract Research Organisations (Richmond Pharmacology, Simbec-Orion), with additional academic drug-discovery engagement (Cardiff University's Medicines Discovery Institute on MDI-26478 for cognitive decline in schizophrenia). The company is ISO 9001:2015 and ISO 27001:2013 certified and draws on an extended consulting network of academic neuroscientists from Oxford, Bristol, Trinity College Dublin, King's College London, the University of Nottingham, and the University of Cagliari.
Revenue mechanics are split between two professional services streams — clinical research services sold to sponsors and CROs, and technical consultancy for IND-enabling and proof-of-concept trial design (biomarker strategy, dose optimization, population enrichment) — delivered via direct enterprise sales and amplified through content marketing (website blog/news), LinkedIn, technical webinars, and industry conferences such as Anglonordic Life Science Conference 2026. Pricing is quote-based and not publicly disclosed; no revenue, funding, or headcount growth figures are available in the public record.
The Science Behind firmographics
Firmographics- Name
- The Science Behind
- Legal name
- Brainbox Ltd
- Website
- https://thesciencebehind.com
- Company type
- Private
- Founded year
- 2016
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- The Science Behind is a Cardiff-based specialist clinical research services provider that integrates non-invasive neurostimulation (TMS), EEG, and Quantitative Sensory Testing into Phase I CNS drug trials for biotech, pharma, and CRO clients.
- Ownership category
- akta.pro rank
The Science Behind industry classification
Industry- Product category
- Clinical Research Services (CNS / Neuroscience)
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171), Scientific Research and Development Services (5417)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Medical Laboratories (8071)
- akta.pro primary industry
- Clinical Trial Site Operations & Study Coordination (HLAGACAE)
- akta.pro secondary industries
- Clinical Biomarker Testing Services (central labs, trial enrollment/monitoring assays) (HLAAAMAC), Clinical Development (Phase I–III Trial Design & Execution) (HLAIALAE)
Keywords
Where The Science Behind is headquartered
LocationHeadquarters
- HQ city
- Cardiff
- HQ country
- United Kingdom
- HQ region
- Europe
Offices1 record
Markets served
The Science Behind business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales
Revenue model
- Clinical Research Services: Specialist neuroscience support services provided to pharmaceutical companies and CROs on a study-by-study basis. Services include protocol design, equipment provision, site training, data collection, quality control, and analysis for Phase I clinical trials. No capital investment required from clients.
- Technical Consultancy: Expert consultancy services for clinical trial design, particularly for IND-enabling and proof-of-concept trials. Includes biomarker strategy, dose optimization, and population enrichment strategies.
Go-to-market motion2 records
Distribution channels1 record
Marketing channels4 records
The Science Behind product offering
Product offeringCore offering
The Science Behind provides specialist neuroscience clinical research services for early-phase (Phase I) CNS drug trials, integrating non-invasive neurostimulation (TMS), neuroimaging (EEG), cognitive and physiological assessments, and Quantitative Sensory Testing (QST) to deliver objective pharmacodynamic and target-engagement readouts. Offerings are delivered study-by-study and span protocol design, provision of specialized equipment, site staff training, on-study deployment, and centralized data analysis for pharmaceutical and biotech sponsors and CROs.
Product overview
The Science Behind is a specialist neuroscience services provider offering an integrated portfolio of non-invasive neurostimulation and neuroimaging solutions for Phase I clinical trials. The core offering comprises four interconnected service modules: Pharmaco-TMS (transcranial magnetic stimulation for cortical excitability assessment), Pharmaco-EEG (quantitative EEG for brain activity monitoring), Cognitive & Physiological Assessments (cognitive test batteries and physiological monitoring), and Quantitative Sensory Testing (standardised pain and sensory threshold evaluation). These multimodal solutions are designed to work independently or in combination, enabling clients to obtain objective measures of target engagement, dose response, and drug effect timing in early-phase CNS drug development.
Differentiator
Problem solved
Functional benefit
Quantifiable outcome
- EEG biomarkers consistent with anxiolytic drug profiles demonstrated in Phase I trials
- +1 more outcomes
Companies that use The Science Behind
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles3 records
The Science Behind technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
The Science Behind partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Brainbox Ltdparent companyBrainbox Ltd is the parent company of The Science Behind. The Science Behind operates as a trading name of Brainbox Ltd, registered in England and Wales.
Scale indicators3 records
Recent moves6 records
Expansion highlights6 records
The Science Behind competitors and assessment
Company assessmentDirect peers
- IXICO: Specialist neuroimaging biomarker CRO serving CNS clinical trials including Alzheimer's and other neurological indications. Comparable to The Science Behind's neuroimaging-enabled Phase I support and similar asset-light deployment model.
- Biotrial: France-headquartered early-phase CRO with strong CNS and neurology expertise. Competes for Phase I CNS trial work and offers similar EEG/TMS-adjacent capabilities to The Science Behind.
- QPS Holdings: Early-phase CRO with strong neuroscience and biomarker capabilities including CNS trials. Directly comparable to The Science Behind's Phase I CNS service offering.
- Beacon Biosignals: US-based CNS trial analytics company specializing in EEG-based biomarkers for clinical trials. Directly comparable to The Science Behind's Pharmaco-EEG offering and competing for the same CNS Phase I/II sponsor budgets.
- Cumulus Neuroscience: Provides EEG and cognitive biomarker platforms specifically for CNS clinical trials. Competes head-to-head with The Science Behind's Pharmaco-EEG and cognitive assessment services for sponsor and CRO clients.
- Richmond Pharmacology: UK-based Phase I clinical trial CRO — also an existing partner of The Science Behind. Directly competes for Phase I CNS work and represents both a customer and a comparable service provider.
- Celerion: Global early-phase clinical research CRO with CNS and neuroscience experience. Comparable service portfolio and target customers (biotech/CRO sponsors running Phase I studies).
- Simbec-Orion: Welsh-based early-phase clinical research CRO with a Phase I accredited unit — also an existing partner. Overlaps with The Science Behind on Phase I CNS trial delivery.
Broad incumbents
- Worldwide Clinical Trials: Mid-size global CRO with a dedicated CNS/neuroscience therapeutic area. Larger and broader than The Science Behind but competes for the same Phase I/II neuroscience trial work.
- Clario: Large clinical trial technology and biomarker company offering EEG, imaging, and digital endpoints across CNS trials. Overlaps with The Science Behind's CNS electrophysiology work as a much larger established player.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights6 records
Customer concentration
The Science Behind social profiles
Digital presenceThe Science Behind compliance and trust
Trust signalCompliance2 records
The Science Behind financial estimates
Financial estimateRevenue estimate
Valuation estimate
The Science Behind leadership team
Management profileNumber of profiles
Profiles7 records
The Science Behind funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
The Science Behind M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about The Science Behind
What does The Science Behind do?
The Science Behind provides specialist neuroscience clinical research services for early-phase (Phase I) CNS drug trials, integrating non-invasive neurostimulation (TMS), neuroimaging (EEG), cognitive and physiological assessments, and Quantitative Sensory Testing (QST) to deliver objective pharmacodynamic and target-engagement readouts. Offerings are delivered study-by-study and span protocol design, provision of specialized equipment, site staff training, on-study deployment, and centralized data analysis for pharmaceutical and biotech sponsors and CROs.
Is The Science Behind a public or private company?
The Science Behind is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was The Science Behind founded?
The Science Behind was founded in 2016. It employs 1 to 10 people.
Where is The Science Behind based?
The Science Behind is headquartered in Cardiff, United Kingdom, in the Europe region.
How does The Science Behind make money?
Two revenue lines are on record. Clinical Research Services are the primary driver. The others are technical Consultancy.
Who are The Science Behind's main competitors?
Direct peers on record are IXICO, Biotrial, QPS Holdings, Beacon Biosignals, Cumulus Neuroscience, Richmond Pharmacology, Celerion and Simbec-Orion. Broad incumbents are Worldwide Clinical Trials and Clario.
Does The Science Behind have an API?
No public API is recorded for The Science Behind.
What industry is The Science Behind in?
The Science Behind's product category is Clinical Research Services (CNS / Neuroscience). Its primary akta.pro industry code is HLAGACAE, Clinical Trial Site Operations & Study Coordination, with a secondary code of HLAAAMAC, Clinical Biomarker Testing Services (central labs, trial enrollment/monitoring assays). Its NAICS code is 541714 and its SIC code is 8731.