Zmt Zurich Medtech Ag

What Zmt Zurich Medtech Ag does

ZMT Zurich MedTech AG, founded in 2006 and headquartered in Zurich, Switzerland, develops the Sim4Life multi-physics simulation platform and a complementary line of MRI implant-safety validation hardware for in silico design, testing, and regulatory evidence generation of medical devices. The company operates as a privately held member of the Z43 strategic alliance alongside IT'IS Foundation (tissue-property research and Virtual Population phantoms), SPEAG (electromagnetic measurement systems), and TI Solutions AG (neuromodulation hardware). Sim4Life combines electromagnetic, thermal, acoustic, and neural solvers with AI-driven segmentation from MRI/CT, the proprietary Generalized Activating Function for fast neural response prediction (up to 1000x faster than NEURON at R²=0.99), and a multi-objective genetic algorithm optimizer; the platform is delivered as perpetual desktop licenses and via tiered cloud platforms (sim4life.io commercial, sim4life.science academic, s4l-lite.io free for students). The validation hardware line includes the MITS family (MITS-TT, MITS-TT-LF, MITS1.5, MITS3.0, MITS-HFR, MITS GRADIENT), piX analyzers (including the new piXAV3), TFD temperature-field detectors, ELIT/ASTM/DUAL_CYL phantoms, TSM field probes, and SAIMD reference devices, supporting ISO 10974 Tier 3 compliance and FDA-recognized safety evaluation.

Revenue is generated through three streams: (1) Sim4Life software licensing — recurring cloud subscriptions for commercial and academic users, multi-year/perpetual desktop licenses for enterprise, and free student access serving as a demand-generation funnel; (2) validation hardware sales of MITS and piX systems with direct and channel-reseller support; and (3) professional services in implant safety testing, regulatory evidence production, and device optimization delivered jointly with IT'IS Foundation. The go-to-market combines direct enterprise sales, a global distributor network (notably AUDEN Techno Corp. for Taiwan and China), targeted presence at industry conferences (ISMRM, NANS, Brain Stimulation, Swiss MedTech Day), and freemium student adoption that builds a future academic and industry user pipeline. Named customers span medtech imaging (GE Healthcare, United Imaging), government research (NIST), academic medical centers (University Health Network Toronto), and universities (EPFL, University of Pennsylvania, Gachon, University of Houston). The product portfolio was further expanded in 2024–2026 into temporal interference neuromodulation via TIBS-R hardware and TIP planning software with TI Solutions, plus the BraiNN whole-brain modeling platform.

Name

Zmt Zurich Medtech Ag

Legal name

ZMT Zurich MedTech AG

Website

https://www.zmt.swiss

Company type

Private

Operating status

Operating

Short description

ZMT Zurich MedTech AG develops the Sim4Life multi-physics simulation platform and MRI implant-safety validation hardware used by medical device manufacturers, researchers, and clinicians to perform in silico testing, regulatory safety evaluation, and optimization of implants and neurostimulation technologies.

Ownership category

akta.pro rank

Product category

Medical Device Simulation Software

NAICS

Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Irradiation Apparatus Manufacturing (334517)

SIC

Electromedical & Electrotherapeutic Apparatus (3845), Industrial Instruments For Measurement, Display, And Control (3823)

akta.pro primary industry

Implantable Neuromodulation & Neurostimulation (SCS/DBS/VNS/PNS) (HLAHAEAK)

akta.pro secondary industry

Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim) (HLAHABAH)

Keywords

• Medical device simulation
• Computational life sciences
• MRI implant safety
• Neurostimulation modeling
• In silico testing

Headquarters

HQ city

Zurich

HQ country

Switzerland

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Sim4Life Software Licenses: Cloud-based and desktop software licensing for commercial, academic, and student users. Commercial users access via sim4life.io, academics via sim4life.science, and students via s4l-lite.io (free). Desktop installers available for enterprise deployment.
2. Validation Hardware Systems: Sale of MRI implant safety test systems including piX analyzers, MITS systems (MITS-TT, MITS-TT-LF, MITS1.5, MITS3.0, MITS-HFR, MITS Gradient), TFD systems, phantom models (ELIT1.5, ELIT3.0, ASTM2009, DUAL_CYL_TFD), TSM sensors, and SAIMD reference devices.
3. Professional Services: Testing services and customized research services backed by IT'IS Foundation expertise, including in silico regulatory evidence production, implant safety testing, and device optimization.

Pricing tiers

Go-to-market motion3 records

Distribution channels6 records

Marketing channels7 records

Core offering

ZMT Zurich MedTech AG develops the Sim4Life multi-physics simulation platform and a complementary line of MRI implant safety measurement systems (MITS, piX, TFD, phantoms, TSM, SAIMD). The combined software and hardware portfolio enables medical device manufacturers, academic researchers, and regulators to perform in silico modeling and physical testing of implants, neurostimulation devices, MRI coils, and wireless/wearable devices for anatomical interaction, physiological response prediction, and ISO 10974-compliant safety assessment.

Product overview

ZMT Zurich MedTech AG offers Sim4Life as its core multi-physics simulation platform for medical technology and computational life sciences, available in desktop (Sim4Life), cloud (Sim4Life.web), academic (Sim4Life Science), and free student (Sim4Life Lite) versions. The platform integrates with anatomical models from IT'IS Foundation and supports neurostimulation, MRI safety, and implant analysis workflows. Complementing the software, ZMT provides a comprehensive Validation Hardware product line including MITS systems (MITS-TT, MITS-TT-LF, MITS1.5, MITS3.0, MITS-HFR, MITS GRADIENT) for MRI implant safety testing, piX analyzers for RF heating measurements, TFD systems, test phantoms, TSM field probes, and SAIMD reference devices. The product portfolio also includes TIBS-R neuromodulation hardware and TIP planning software developed in partnership with TI Solutions AG for temporal interference brain stimulation applications, along with BraiNN for whole-brain network modeling. This integrated hardware-software ecosystem enables medtech companies and researchers to perform in silico testing, device optimization, and regulatory safety assessments.

Differentiator

Problem solved

Functional benefit

Brands

• Sim4Life: Premier multi-physics simulation platform for medical technology development, device interaction with anatomy, and physiological response prediction
• MITS
• piX System

Products and services

• Sim4Life (desktop simulation platform) Premier multi-physics simulation platform for medical technology development, neurostimulation modeling, MRI safety, and implant safety evaluation. Combines electromagnetic (high/low frequency), thermal, acoustic, and electrophysiological solvers with neural tissue models, targeted at medtech R&D engineers, regulatory specialists, and academic researchers.
• Sim4Life.web (cloud commercial platform) Cloud-based commercial version of the Sim4Life platform accessible via web browser with full features including HPC/GPU compute, advanced multi-objective optimization, and integrated AI workflows. Sold to enterprise medtech customers on annual subscription via sim4life.io.
• Sim4Life Science (academic cloud platform) Academic cloud version of Sim4Life providing researchers with free cloud credit eligibility, full ViP model library access, JupyterLab integration, and the Sim4Life Python API. Targeted at university and clinical research labs.
• Sim4Life Lite (student platform) Free cloud-based version of Sim4Life for undergraduate and graduate students from registered universities; limited to 20 million grid cells with no HPC/cloud computing and renewable annually until one year after graduation. Builds future commercial and academic users.
• MITS Systems (MITS-TT, MITS-TT-LF, MITS1.5, MITS3.0, MITS-HFR, MITS GRADIENT) Family of Medical Implant Test Systems used to evaluate RF and gradient safety of active and passive implants in 1.5T, 3.0T, high-field, and 0.55T MRI environments per ISO 10974. Sold to medtech manufacturers, test labs, and regulatory teams.
• piX System (incl. piXAV3) Vector network analyzer-based system for precise in vivo prediction of RF heating and induced voltage during MRI, supporting ISO 10974 implant risk evaluations across conventional and low-field MRI. Sold to implant manufacturers and test labs.
• TFD System Temperature Field Detector system for thermal measurements in MRI environments, used to calibrate and validate MRI-induced heating predictions in phantoms and implants.
• Test Phantoms (ELIT1.5, ELIT3.0, ASTM2009, DUAL_CYL_TFD) Physical test phantoms for electromagnetic measurements and calibration, including ELIT1.5, ELIT3.0, ASTM2009, and DUAL_CYL_TFD models. Sold to implant manufacturers, MRI vendors, and test laboratories.
• TSM Test System Modules Modular electromagnetic field probes including TLe and TGe series probes and HSL300 for field measurements across various frequencies and applications. Sold as OEM-grade measurement components.
• SAIMD Reference Devices Surface Active Implantable Medical Device reference devices (SAIMD-1-200mm, SAIMD-1-100mm, SAIMD-U, SAIMD-U-Wire) used for calibration and validation of implant safety testing systems.
• TIBS-R (Temporal Interference Brain Stimulator for Research) Multichannel neuromodulation research device for advanced temporal interference brain stimulation studies, developed with TI Solutions AG and Z43 alliance partners. Offered to neuromodulation research labs and centers.
• TIP (Temporal Interference Planning tool) Planning software for personalized temporal interference stimulation modeling with surrogate-model-based optimization, local personalization, and full Sim4Life workbench integration. Used by clinical researchers in neuromodulation.
• BraiNN Personalized whole-brain network modeling solution combining EEG-informed and state-aware neuromodulation, GPU-accelerated for clinically affordable personalized treatment planning in functional neuroscience.
• Professional Testing and Research Services Project-based testing services and customized research engagements backed by IT'IS Foundation expertise, including in silico regulatory evidence production, implant safety testing, MRI safety evaluations, and device optimization consulting. Sold to medtech companies and regulatory submitters.

Quantifiable outcome

• 5x reduction in energy consumption for spinal cord stimulation while maintaining equal recruitment
• +4 more outcomes

Named customers8 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration7 records

AI capability11 records

Feature7 records

Partnerships

Eight partnerships are on record, tiered core, major and minor.

• TI Solutions AGcoreStrategic or Co-development Partner · 7 July 2026TI Solutions AG develops and sells the Temporal Interference Brain Stimulator for Research (TIBS-R) and collaborates on the TIP (Temporal Interference Planning) tool. Jointly exhibits at neuromodulation conferences. Part of Z43 alliance since 2019.
• IT'IS FoundationcoreStrategic or Co-development Partner · 26 May 2026IT'IS Foundation is the key strategic research partner providing the Virtual Population (ViP) computational phantoms, tissue properties databases (MRIxViP), and customized research services. Jointly develops Sim4Life capabilities and provides validation services. Founded in 2000, part of Z43 alliance.
• SPEAG (Schmid & Partner Engineering AG)coreStrategic or Co-development PartnerSPEAG provides electromagnetic phantoms, cSAR3D measurement systems, and DASY8 platform for SAR testing. Co-hosts annual distributor week and develops complementary measurement tools. Founding member of Z43 alliance (30 years in 2024).
• AUDEN Techno Corp.majorChannel Partner/ Reseller/ DistributorAUDEN Techno Corp. is the primary distributor and workshop organizer for Taiwan and China markets. Has hosted the 19th consecutive annual workshop series with Z43, organizing events in Taipei, Beijing, Shanghai, and Shenzhen.
• TUOPUMEDmajorStrategic or Co-development PartnerTUOPUMED collaborates with ZMT on medical industry workshops, focusing on computational life sciences and Sim4Life training in the China market. First year of joint medical industry session organization in 2026.
• Swiss MedtechminorGTM or Marketing PartnerParticipated in Swiss MedTech Day 2026 to present in silico medtech computational modeling tools to Swiss medtech industry audience.
• NeuroRestore (EPFL/CHUV)minorStrategic or Co-development PartnerNeuroRestore collaborated with IT'IS researchers on developing the GAF method for clinical spinal cord stimulation planning, validating the approach against published clinical workflows.
• Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)minorStrategic or Co-development PartnerFAU researchers collaborated on developing the GAF fast predictor for MRG axon models, contributing to the clinical applicability of neural response prediction.

Scale indicators4 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• ANSYS: ANSYS is the leading horizontal CAE platform with HFSS for electromagnetic simulation, increasingly applied to medical device design and MRI safety. Comparable as a multiphysics simulation platform serving overlapping customers (med device R&D, MRI manufacturers), but operates at much broader scope and scale than ZMT's medtech specialization.
• Altair Engineering: Altair offers Feko for electromagnetic simulation, including biomedical and MRI-related use cases. Comparable as an EM simulation vendor serving some overlapping customers in wireless device design and implant analysis, though broader in scope and less specialized in neurostimulation-specific workflows than ZMT.
• COMSOL: COMSOL provides a multiphysics simulation platform with biomedical modules used by researchers and engineers for bioelectromagnetics, neurostimulation, and implant analysis. Directly competes with Sim4Life in academic and commercial simulation workflows, but offers a broader horizontal platform without ZMT's neurostimulation-specific solver stack or integrated ViP anatomical models.
• Dassault Systèmes (SIMULIA): Dassault's SIMULIA portfolio includes the Living Heart Project, a validated in silico cardiac simulation initiative with FDA engagement. Comparable as an in silico medical device simulation platform with regulatory pathway ambitions, but focused on cardiovascular structural modeling rather than ZMT's neurostimulation and MRI safety specialization.

Others

• Siemens Healthineers: Siemens Healthineers is a major MRI manufacturer and is referenced in ZMT's standards ecosystem (ISO 10974, MR safety). Not a direct simulation competitor, but a critical customer-adjacent partner whose MRI product roadmaps (including low-field systems) shape demand for ZMT's validation hardware and MRI safety simulation tools.
• GE Healthcare: GE Healthcare is a leading MRI manufacturer and an existing ZMT customer (ISMRM Safety Subgroup representation). Not a simulation competitor, but an ecosystem partner whose MRI system design decisions (5T, low-field variants) drive demand for both Sim4Life and ZMT's MITS/piX validation hardware.
• SPEAG (Schmid & Partner Engineering AG):

Direct peers

• Remcom: Remcom provides electromagnetic simulation software (XFdtd, Wireless InSite) used for MRI safety analysis, wireless device design, and biomedical EM applications. Comparable as a specialized EM simulation vendor with overlap in MRI safety and implant analysis workflows, though smaller scale and less specialized in neurostimulation-specific solvers than Sim4Life.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks1 record

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/channel/UC1qJCi7lu_UUS6wlMoxK_DA
• LinkedInlinkedin.com/company/zurich-med-tech

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zmt Zurich Medtech Ag