Pentagen

What Pentagen does

PentaGen s.r.o. is a Czech privately-held limited liability company founded in 2007 by Jiří Čížek and Ivana Čížková, headquartered in Kladno, Czech Republic. The company is a specialized distributor of laboratory diagnostic and assisted reproduction (IVF) products, operating two business divisions — Reproduction and Molecular Diagnostics — across four Central/Eastern European markets: the Czech Republic, Slovakia, Hungary, and Poland. PentaGen holds exclusive distribution rights for more than 28 international manufacturers, including Vitrolife (EmbryoScope time-lapse systems, vitrification and culture media), Integrated DNA Technologies (xGen NGS reagents), Devyser (CE-IVDR certified diagnostic kits), MRC Holland (SALSA MLPA and digitalMLPA technology), SeqOne Genomics (NGS interpretation platform), Biotype, Paragon Genomics, Protrans, and Lexogen.

The product portfolio spans the full IVF workflow — oocyte retrieval, culture media, vitrification/warming solutions, slow-freezing kits, ICSI consumables, sperm preparation, EmbryoScope time-lapse incubation systems with AI-augmented evaluation software (KIDScore D3/D5, iDAScore, Guided Annotation), transfer catheters, and endometrial receptivity tests (EndomeTRIO, ora, EMBRACE) — and a comprehensive molecular diagnostics offering including NGS library prep and panels, MLPA/digitalMLPA probemixes, hereditary cancer and CFTR testing, aneuploidy screening, chimerism monitoring, FISH probes, HLA typing, microbiology rapid tests, allergy panels, and karyotyping media. Technical support, installation, troubleshooting, and training are bundled with product distribution as a value-added service.

The business model is sales-led with a territory-based portfolio manager structure (Reproduction Division; Diagnostics Division for CZ/PL and SK/HU), generating revenue primarily through product distribution margins and, secondarily, through professional services (training, technical support, and increasingly direct EmbryoScope service in CZ/SK). The company is ISO 13485:2016 and ISO 9001:2016 certified, founder-owned with no disclosed institutional investors, and operates a multi-language website (CZ/EN/PL/HU) and active conference presence across CEE life-science events.

Name

Pentagen

Legal name

PentaGen s.r.o.

Website

https://pentagen.cz

Company type

Private

Founded year

2007

Operating status

Operating

Headcount range

11–50 employees

Short description

PentaGen s.r.o. is a Czech-based specialized distributor of laboratory diagnostic and assisted reproduction (IVF) products, representing 28+ international manufacturers across Czech Republic, Slovakia, Hungary, and Poland, and serving hospitals, IVF centers, and diagnostic laboratories with full technical and training support.

Ownership category

akta.pro rank

Product category

Medical Device Distribution

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047), In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)

akta.pro secondary industries

Genomics & Molecular Diagnostics (Trial Support) (HLAGAEAD), Molecular Diagnostics & Genomics Laboratories (HLAFAMAE)

Keywords

• Laboratory diagnostics distribution
• IVF products distribution
• Molecular diagnostics supplies
• Assisted reproduction equipment
• Medical device distribution

Headquarters

HQ city

Central

HQ country

Hong Kong SAR China

HQ region

Asia

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Marketing or Sales, Operations, Technology or R&D

Revenue model

1. Product Distribution - Reproduction: Distribution of products for assisted reproduction including media, consumables, instruments, and software for IVF centers. Revenue generated through product sales to fertility clinics and hospitals.
2. Product Distribution - Molecular Diagnostics: Distribution of molecular diagnostic products including NGS reagents, diagnostic kits, and testing solutions to laboratories and hospitals. Revenue generated through product sales and distribution margins.
3. Technical Support and Training Services: Comprehensive training in working with distributed products, including troubleshooting solutions, installation support, and ongoing technical assistance. Provided as value-added service supporting product sales.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

PentaGen is a specialized Central European distributor that supplies laboratory diagnostics products and assisted reproduction (IVF) solutions to hospitals, diagnostic laboratories, and fertility clinics in Czech Republic, Slovakia, Hungary, and Poland. The portfolio spans two divisions — Reproduction (IVF culture media, vitrification/warming solutions, time-lapse incubators with AI software, transfer catheters, sperm preparation) and Molecular Diagnostics (NGS reagents and panels, MLPA/digitalMLPA probemixes, HLA typing kits, FISH probes, BRCA/CFTR genetic tests, microbiology rapid tests, and bioinformatics software). The company represents over 28 international manufacturers, provides installation, training, and ongoing technical support, and holds ISO 13485:2016 and ISO 9001:2016 certifications for medical device distribution.

Product overview

Pentagen offers a comprehensive portfolio of laboratory diagnostic products and assisted reproduction (IVF) solutions across two main categories. For reproduction/IVF, the portfolio includes culture media (G-IVF™PLUS, G-2™PLUS, G-MOPS™PLUS, EmbryoGlue™), vitrification and warming solutions (RapidVit™/RapidWarm™ Omni, Ultra RapidWarm™ Blast), slow freezing kits, sperm preparation products (SpermGrad™, SpermFreeze), oocyte retrieval needles, ICSI solutions (ICSI™, HYASE™), EmbryoScope time-lapse incubation systems with AI-powered evaluation software (KIDScore D3/D5, iDAScore, Giuded Annotation), transfer catheters, and endometrial/receptivity tests (EndomeTRIO, ora™, EMBRACE). For molecular diagnostics, the portfolio encompasses NGS library prep and panels (xGen™ products from IDT, CORALL RNA-Seq), MLPA and digitalMLPA technology (SALSA® MLPA® probemixes), bioinformatics software (SeqOne platform), hereditary cancer testing (Devyser BRCA NGS, Devyser CFTR NGS), aneuploidy screening (Devyser Compact, Devyser Complete CE-IVDR), reproductive genetics panels, chimerism monitoring (Mentype® Chimera®), FISH probes (FastProbe kits), microbiology rapid tests (eazyplex® panels), allergy testing (Allergy-Q Panels), karyotyping media, HLA typing solutions (Protrans), and sperm quality analyzers. The company operates as a distributor representing international manufacturers including Vitrolife, IDT, Devyser, MRC Holland, Biotype, and others across Czech Republic, Slovakia, Hungary, and Poland.

Differentiator

Problem solved

Functional benefit

Products and services

• EmbryoScope Time-Lapse Incubation Systems Vitrolife-branded time-lapse embryo incubators (EmbryoScope D, EmbryoScope+, EmbryoScope8) with integrated camera systems for continuous embryo monitoring and development tracking in IVF labs.
• KIDScore D3/D5 and iDAScore AI Evaluation Software AI-assisted embryo evaluation software modules (KIDScore D3/D5, iDAScore, Giuded Annotation) that analyze morphokinetic parameters from EmbryoScope time-lapse imagery to select the best embryo for transfer.
• RapidVit / RapidWarm Omni Vitrification Solutions CE-certified vitrification (RapidVit Omni) and warming (RapidWarm Omni) media for embryo and oocyte cryopreservation, plus Rapid-i Kit closed carriers.
• Ultra RapidWarm Blast Single-step warming solution for vitrified blastocysts, simplifying IVF lab workflow while maintaining clinical outcomes.
• FREEZE-Kit Cleave and THAW-Kit Cleave CE-certified slow freezing and thawing kits for cleavage-stage embryos.
• Vitrolife G-Series IVF Culture Media Sequential IVF culture media portfolio (G-IVF PLUS, G-2 PLUS, G-MOPS PLUS, EmbryoGlue) for oocyte/embryo handling and embryo transfer.
• OVOIL Culture Oil Ultra-pure paraffin oil for embryo culture.
• ICSI and HYASE Micromanipulation Solutions ICSI sperm handling solution and HYASE hyaluronidase enzyme for oocyte denudation during ICSI procedures.
• SpermGrad and SpermFreeze Sperm Preparation Solutions Gradient medium (SpermGrad) for sperm preparation/selection and cryopreservation solution (SpermFreeze) for sperm freezing.
• Oocyte Retrieval Needles Conventional single-lumen, double-lumen, and Sense echogenic oocyte retrieval needles for IVF pickup.
• LensHooke CA0 Sperm Selection Device MDR-certified separation dish for selecting the best sperm without centrifugation.
• Frydman and FULL ECHO PRO Transfer Catheters Single-piece (Frydman) and three-piece echogenic (FULL ECHO PRO) embryo transfer catheters for controlled embryo transfer.
• Semen Quality Analyzer X1/X3/X12 PRO Sperm quality analyzers compliant with WHO 6th Edition for semen analysis.
• EMBRACE Non-Invasive PGT Test Non-invasive preimplantation genetic test for assessing embryo euploidy without biopsy.
• EndomeTRIO and ora Endometrial Receptivity Tests EndomeTRIO provides comprehensive endometrial analysis for receptivity testing; ora is a non-invasive endometrial receptivity test.
• EmbryoMap and KaryoMap v2 PGT Solutions EmbryoMap for PGT-A and PGT-SR aneuploidy/structural chromosomal diagnosis; KaryoMap v2 for PGT-M monogenic disease diagnosis.
• SALSA MLPA and digitalMLPA Probemixes Gold-standard MRC Holland probemixes for quantifying copy numbers in up to 60 different genomic DNA sequences simultaneously; digitalMLPA panels for hereditary cancer and hematological CNV analysis.
• xGen NGS Library Prep Kits IDT xGen DNA EZ, cfDNA & FFPE DNA Library Prep, and Methyl-Seq kits for streamlined NGS library preparation from various input types.
• xGen Custom Hyb Capture Panels and Exome Hyb Panel v2 IDT-manufactured custom hybrid capture NGS panels and whole exome panel covering 19,435 genes.
• Archer VariantPlex and FusionPlex NGS Panels Archer NGS panels using AMP technology for SNV/InDel/CNV detection (VariantPlex, hematological and solid tumors) and gene fusion/alternative splicing detection (FusionPlex).
• Devyser BRCA and CFTR NGS Kits IVDR-certified Devyser NGS kits for detecting germline/somatic SNVs and CNVs in BRCA1/BRCA2 and CFTR genes.
• Devyser Compact CE-IVDR Aneuploidy Test CE-IVDR-certified QF-PCR test for prenatal diagnosis of aneuploidy of chromosomes 13, 18, 21, X, and Y.
• Mentype Chimera Chimerism Monitoring Kit Qualitative and quantitative detection of 12 STR markers for chimerism monitoring after hematopoietic stem cell transplantation.
• GynTect, ScreenYuGyn, and CISCER Cervical Cancer Tests Kits for determining risk of cervical cancer using bisulfite conversion, rtPCR, and methylation markers (PAX1, JAM3).
• eazyplex Microbiology Panels Rapid LAMP-based molecular diagnostic panels for infectious diseases including Candida auris, Pneumocystis jirovecii, C. difficile, MRSA, VRE, and STDs.
• FastProbe FISH Probe Kits FISH probes with shortened hybridization time and high specificity for pathology and hemato-oncology applications.
• Protrans HLA NGS Typing Kits NGS systems for efficient HLA typing including N5/N5LR11 versions and celiac disease HLA typing.
• DNA Profiling Kits Kits for detection of autosomal and gonosomal STR markers applied in DNA profiling, forensics, and paternity testing.
• SeqOne Genomic Analysis Platform Bioinformatics software with intuitive user interface and automated processes for clinical and research NGS data interpretation.
• CORALL RNA-Seq Library Prep Kits Lexogen library preparation kits for whole transcriptome sequencing by analysis of total RNA or mRNA.
• Cytogen Karyotyping Media (CytogenPrena, CytogenAmnio, CytogenMarrow, CytogenLympho) Specialized media for karyotyping including chorionic tissue, amniotic fluid, bone marrow cell, and lymphocyte culture.
• Allergy-Q Panels PROTIA-certified panels for detection of specific IgE antibodies against various allergens based on immunoblot technology.
• SISCONE Sonohysterography Solution Medical device solution for sonohysterography with reduced media leakage.
• VitroTemp Digital Temperature Monitoring Instrument Digital readout instrument and probe kit for temperature monitoring during embryo culture.

Quantifiable outcome

• Company holds ISO 13485:2016 and ISO 9001:2016 certifications for quality management

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature4 records

Partnerships

27 partnerships are on record, tiered core, major and minor.

• VitrolifecoreChannel Partner/ Reseller/ DistributorGlobal company providing products and services for assisted reproduction. PentaGen distributes Vitrolife products including EmbryoScope time-lapse systems, vitrification media (RapidVit, RapidWarm), culture media (G-Series), and related IVF consumables in Czech Republic, Slovakia, Hungary, and Poland.
• Integrated DNA Technologies (IDT)coreChannel Partner/ Reseller/ DistributorAmerican company offering xGen NGS reagents, xGen panels, and Archer AMP panels including pre-designed and custom panels. PentaGen distributes IDT products for NGS workflows in its served territories.
• DevysercoreChannel Partner/ Reseller/ DistributorSwedish manufacturer of diagnostic kits based on QF-PCR, AS, and NGS technologies. Products include BRCA testing, CFTR testing, aneuploidy screening kits, and thrombophilia tests, all CE-IVDR certified.
• MRC HollandcoreChannel Partner/ Reseller/ DistributorDutch manufacturer of products based on MLPA and digitalMLPA technology for copy number analysis. PentaGen distributes SALSA MLPA probemixes and digitalMLPA products.
• IgenomixcoreChannel Partner/ Reseller/ DistributorInternational biotechnology company specializing in advanced genetic testing in reproductive medicine. Now part of Vitrolife Group.
• SeqOne GenomicscoreTechnology or IntegrationFrench company focused on genomic analysis tools for NGS data interpretation. PentaGen distributes the SeqOne platform for clinical and research applications in its territories.
• BIOTYPE GmbHmajorChannel Partner/ Reseller/ DistributorGerman company focusing on hemato-oncology diagnostics. Products include Mentype series kits for chimerism, AML, and other hematological applications.
• ExperteammajorChannel Partner/ Reseller/ DistributorItalian manufacturer of AS-FA, PCR, rtPCR, and QF-PCR based diagnostic kits including FRAXA, UPD 15, and LabGscan products.
• Paragon GenomicsmajorChannel Partner/ Reseller/ DistributorManufacturer of NGS kits based on amplicon sequencing using patented CleanPlex and OmniFusion technologies.
• ProtransmajorChannel Partner/ Reseller/ DistributorGerman specialist in HLA typing solutions including Protrans XMatch, Protrans HLA NGS N5/N5LR11, and celiac disease HLA typing products.
• Yikon GenomicsminorChannel Partner/ Reseller/ DistributorManufacturer of products based on whole-genome sequencing and MALBAC technology for preimplantation genetic testing (PGTA) and NICSA.
• Wuhan HealthCareminorChannel Partner/ Reseller/ DistributorCompany specializing in production of FISH probes with shortened hybridization time and high specificity for pathology and hemato-oncology.
• LexogenminorChannel Partner/ Reseller/ DistributorAustrian expert on RNA analysis including whole transcriptome sequencing solutions.
• Inti LabsminorChannel Partner/ Reseller/ DistributorCompany founded by IVF field leaders, striving to improve treatment success through non-invasive and precise diagnostic solutions.
• PROTIA Inc.minorChannel Partner/ Reseller/ DistributorSouth Korean biotechnology company focused on in vitro diagnostic tests, particularly in allergy and immunology diagnostics.
• AmplexDiagnostics GmbHminorChannel Partner/ Reseller/ DistributorPrivately owned German company specializing in rapid molecular diagnostic solutions based on Loop-mediated Isothermal Amplification (LAMP) technology.
• Loop DiagnosticsminorChannel Partner/ Reseller/ DistributorInnovative diagnostic solutions for early detection of severe infections.
• LaCAR MDxminorChannel Partner/ Reseller/ DistributorBelgian manufacturer of CE-IVD kits based on LAMP technology.
• Salus BioMedminorChannel Partner/ Reseller/ DistributorBiotechnology company focused on development of advanced solutions in genomics and next-generation sequencing (NGS).
• Superbio BiomedicalminorChannel Partner/ Reseller/ DistributorSpecialist in forensic DNA testing for criminal investigation, blood centers, research, and forensic genetic laboratories.
• Medicover GeneticsminorChannel Partner/ Reseller/ DistributorManufacturer of TarCET IVD NGS panels for diagnosis of a wide range of diseases including cardiovascular, metabolic, infertility, and hereditary cancer conditions.
• Univ8 GenomicsminorChannel Partner/ Reseller/ DistributorManufacturer of Euro-Clonality NDC for examination of lymphoproliferative diseases.
• CISPOLYminorChannel Partner/ Reseller/ DistributorInnovative company in women's reproductive health offering methylation tests for early detection of gynecological tumors.
• 4bases SAminorChannel Partner/ Reseller/ DistributorManufacturer of a wide range of NGS panels certified for diagnostic use.
• Nucleix Ltd.minorChannel Partner/ Reseller/ DistributorNon-invasive DNA methylation detection company for cancer diagnosis.
• epitype GmbHminorChannel Partner/ Reseller/ DistributorInnovation in DNA methylation diagnostics.
• AMDminorChannel Partner/ Reseller/ DistributorBritish manufacturer of diagnostic kits for infectious diseases based on PCR.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Vitrolife: Swedish global manufacturer of IVF media, consumables, and time-lapse systems (EmbryoScope). PentaGen is a key CEE distributor of Vitrolife; the two share the IVF/ART product line and target fertility clinics but at different levels of the value chain.
• Merck KGaA (Life Science): Global life science tools and IVF/ART products distributor and manufacturer. The Sigma-Aldrich/Merck portfolio of IVF and molecular biology reagents competes with and overlaps several of PentaGen's distributed lines.
• QIAGEN: Global provider of molecular diagnostics sample-prep, assays, and bioinformatics (similar in NGS workflow positioning to PentaGen's SeqOne + IDT + MRC Holland stack). Overlaps in hospital diagnostic lab customers across CEE.
• Bio-Techne: Global developer and distributor of reagents, assays, and instruments for life science and molecular diagnostics. Comparable in its mix of proprietary reagents and distribution of complementary technologies to research and clinical labs.
• CooperSurgical: US-headquartered global leader in IVF/ART and reproductive genetics consumables, devices, and services. Comparable product breadth and fertility-clinic customer base to PentaGen, but operating globally rather than regionally in CEE.
• Thermo Fisher Scientific: Global life sciences tools and diagnostics distributor/manufacturer with broad NGS, PCR, and clinical diagnostics portfolios that overlap with many of PentaGen's molecular diagnostics lines. Serves the same hospital and reference-lab customers at scale.

Regional players

• Diagnostica Stago (or comparable CEE-focused IVD distributor): European specialty IVD and lab diagnostics distributors operating in CEE with hospital and lab relationships. Comparable business model to PentaGen as a regional specialty distributor of advanced diagnostics products.
• BioVendor Group: Czech-based diagnostics and research reagent developer and distributor serving Central and Eastern European clinical and research labs. Closest geographic and product-mix comparable to PentaGen in the CEE region.

Direct peers

• Esco Medical: Manufacturer of MIRI time-lapse incubators and ART workstations. Competes with EmbryoScope in the same IVF time-lapse segment that PentaGen distributes and serves the same CEE clinic base.
• Genea Biomedx: Developer and supplier of IVF lab equipment and consumables (Geri time-lapse incubators, Gems media). Direct comparable in the IVF/ART product category PentaGen distributes, serving the same fertility clinic end market.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/pentagen

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pentagen