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NCBI

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uuid02lot4k

Namestring
NCBI
Legal namestring
National Institutes of Health (NIH)
Websiteurl
nih.gov
Company typeenum
Public
Founded yearint
1887
Descriptiontext

NCBI's strategic posture is that of a public-good platform rather than a competitive business: its priorities are database curation breadth, tool reliability, and global accessibility rather than revenue or market share. Strategic signals in the recent period include the April 2025 appointment of Dr. Jay Bhattacharya as 18th NIH Director, the addition of the Comparative Genomics Resource to the product surface, sustained investment in BLAST+, and an NIH-wide website modernization initiative. With 501-1000 employees and a congressionally chartered mandate, NCBI operates as durable, government-backed infrastructure for the global biomedical research community.

Short descriptiontext

NCBI, a division of the U.S. National Library of Medicine at NIH, maintains public biomedical databases and analysis tools including PubMed, BLAST+, GenBank, and the Comparative Genomics Resource, serving researchers, clinicians, and educators worldwide free of charge.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
251–500
akta.pro rankint
HeadquartersBethesda, United States
HQ citystring
Bethesda
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
biomedical databases, bioinformatics tools, genomic data repositories, sequence similarity search, computational biology resources
Industry3 codes
1Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics)
CodeHLAAALADPrimaryYes
2Genomics & Molecular Diagnostics (Trial Support)
CodeHLAGAEADPrimaryNo
3Molecular Diagnostics & Genomics Laboratories
CodeHLAFAMAEPrimaryNo
NAICS code3 codes
  • Scientific Research and Development Services5417
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
  • Research and Development in the Physical, Engineering, and Life Sciences54171
SIC code1 code
  • Services-Commercial Physical & Biological Research8731
Product category
Bioinformatics databases and computational biology tools
GTM motion1 record

Each record includes

Type, Description, Source

Revenue model1 record
1Public Government Funding
TypeSubscription Recurring
Description

NCBI operates as a government-funded entity under the National Institutes of Health, supported by congressional appropriations and taxpayer funding. Services are provided free of charge to researchers, healthcare professionals, and the public worldwide.

linkedin.com
Marketing channels5 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels2 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components4 values
Personnel, Technology or R&D, Infrastructure, Operations
Pricing details1 tier
1Free public access to all databases and tools
ModelFreemiumBilling cadenceMonthly
Notes

All NCBI resources including BLAST+, PubMed, GenBank are provided free of charge to researchers, healthcare professionals, students, and the general public worldwide.

linkedin.com
GTM typeB2C
B2C
Offering typeSoftware
Software
Brand1 of 4 records shown
1PubMed
Description

Free online database of biomedical literature citations and abstracts.

linkedin.com
+3 more records
Core offering1 text field

NCBI provides free public access to authoritative biomedical and genomic databases, including PubMed for literature, GenBank for genetic sequences, and BLAST+ for sequence similarity search. It also offers computational biology tools and APIs that enable researchers, healthcare professionals, and students worldwide to conduct genomic analysis, literature searches, and comparative biology research at no cost.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

NCBI (National Center for Biotechnology Information) is a division of the National Library of Medicine at NIH that serves as a major international resource for biological and medical research data. NCBI provides access to a suite of databases, tools, and computational biology resources including PubMed, BLAST+, GenBank, and the Comparative Genomics Resource. The offering is a platform-plus-resources architecture where users access interconnected databases and analysis tools for genomic, biomedical, and bioinformatics research.

Product and service4 records
1PubMed
CategoryCore Database
Description

A free search engine accessing the MEDLINE database of references and abstracts on life sciences and biomedical topics, maintained by NCBI for researchers, healthcare professionals, and the general public.

2BLAST+
CategoryAnalysis Tool
Description

A bioinformatics tool for comparing gene or protein sequences against databases to find regions of similarity, used by researchers for identifying homologous sequences and functional annotation.

3Comparative Genomics Resource
CategoryCore Database
Description

An NCBI resource that facilitates comparative genomic analyses across species to understand evolutionary relationships and genomic conservation, targeted at computational biology researchers.

4GenBank
CategoryCore Database
Description

An annotated collection of publicly available DNA sequences maintained by NCBI, used by researchers worldwide for genomic and genetic sequence analysis.

Scale indicator2 records

Each record includes

Type, Value, Description, Source

Partnership1 partner
1Accelerating Medicines Partnership (AMP)
Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2014-01-01
Description

AMP is a public-private partnership between NIH, FDA, multiple biopharmaceutical and life science companies, and non-profit organizations to transform the current model for developing new diagnostics and treatments. NIH and AMP partners share expertise and resources to enable best-informed contributions to science. NCBI resources support AMP data infrastructure and research coordination.

nih.gov
Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight6 records

Each record includes

Type, Description

Peers10 records
TypeBroad incumbent
Description

Sanger is a large, publicly funded genomics research institute that operates its own data platforms (e.g., COSMIC, Ensembl) and contributes heavily to shared genomic databases. It is comparable to NCBI as a publicly funded life-science data powerhouse but with a broader wet-lab research portfolio.

TypeEmerging player
Description

DNAnexus is a commercial cloud-based bioinformatics platform offering genomics data management and analysis for pharma, clinical, and research customers. It overlaps with NCBI in serving genomic data workflows but operates as a paid, enterprise SaaS rather than a free public resource.

3Swiss Institute of Bioinformatics (SIB)
TypeDirect peer
Description

SIB maintains widely used bioinformatics resources such as UniProt, STRING, and SWISS-MODEL. It is a publicly funded, non-profit bioinformatics infrastructure provider with a mission and operating model closely aligned to NCBI.

TypeBroad incumbent
Description

The Broad Institute is a leading genomics and biomedical research organization that develops widely used tools (e.g., GATK) and hosts major datasets (e.g., gnomAD). It overlaps with NCBI in serving the computational genomics community and contributing to shared reference resources.

5Galaxy Project
TypeEmerging player
Description

Galaxy is an open, web-based platform for accessible genomic data analysis that integrates public datasets (including those from NCBI). It is comparable as a community bioinformatics resource, though its focus is on user-facing analysis workflows rather than primary data archiving.

6National Genomics Data Center (NGDC, China)
TypeDirect peer
Description

NGDC operates a portfolio of open genomic databases (e.g., GSA, BIG) under the Chinese Academy of Sciences, serving as the primary national counterpart to NCBI/GenBank for genomic data submission, archiving, and analysis in China.

TypeBroad incumbent
Description

The Allen Institute is a non-profit medical research organization producing large, openly available reference datasets (e.g., Allen Brain Atlas). It is comparable as a publicly minded, non-profit producer of high-value reference biological data.

TypeBroad incumbent
Description

JGI is a DOE-funded user facility for genomic sequencing and analysis, producing large-scale datasets that often flow into NCBI's archives. It is comparable as a publicly funded genomics data producer, though its focus is on energy and environmental applications.

9DNA Data Bank of Japan (DDBJ)
TypeDirect peer
Description

DDBJ is one of the three founding partners (with GenBank and ENA) of the International Nucleotide Sequence Database Collaboration. It offers a directly comparable public genetic sequence repository for researchers in Asia and globally.

TypeDirect peer
Description

EMBL-EBI is the European equivalent of NCBI, maintaining complementary biological databases (e.g., ENA, UniProt, Ensembl) under a public-good model funded by EMBL member states. It is NCBI's closest international partner and most direct peer in mission, scope, and user base.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat6 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers2 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment3 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile3 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature1 record

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles1 record

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

Subsidiaries27 records

Each record includes

Name, Acquired on, Relationship type, Type, Business focus

No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

NCBI

Bioinformatics databases and computational biology toolsnih.gov

NCBI, a division of the U.S. National Library of Medicine at NIH, maintains public biomedical databases and analysis tools including PubMed, BLAST+, GenBank, and the Comparative Genomics Resource, serving researchers, clinicians, and educators worldwide free of charge.

What NCBI does

NCBI's strategic posture is that of a public-good platform rather than a competitive business: its priorities are database curation breadth, tool reliability, and global accessibility rather than revenue or market share. Strategic signals in the recent period include the April 2025 appointment of Dr. Jay Bhattacharya as 18th NIH Director, the addition of the Comparative Genomics Resource to the product surface, sustained investment in BLAST+, and an NIH-wide website modernization initiative. With 501-1000 employees and a congressionally chartered mandate, NCBI operates as durable, government-backed infrastructure for the global biomedical research community.

NCBI firmographics

Firmographics
Name
NCBI
Legal name
National Institutes of Health (NIH)
Website
https://nih.gov
Company type
Public
Founded year
1887
Operating status
Operating
Headcount range
251–500 employees
Short description
NCBI, a division of the U.S. National Library of Medicine at NIH, maintains public biomedical databases and analysis tools including PubMed, BLAST+, GenBank, and the Comparative Genomics Resource, serving researchers, clinicians, and educators worldwide free of charge.
Ownership category
akta.pro rank

NCBI industry classification

Industry
Product category
Bioinformatics databases and computational biology tools
NAICS
Scientific Research and Development Services (5417), Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171)
SIC
Services-Commercial Physical & Biological Research (8731)
akta.pro primary industry
Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD)
akta.pro secondary industries
Genomics & Molecular Diagnostics (Trial Support) (HLAGAEAD), Molecular Diagnostics & Genomics Laboratories (HLAFAMAE)

Keywords

  • Biomedical databases
  • Bioinformatics tools
  • Genomic data repositories
  • Sequence similarity search
  • Computational biology resources

Where NCBI is headquartered

Location

Headquarters

HQ city
Bethesda
HQ country
United States
HQ region
North America

Offices1 record

Markets served

NCBI business model

Business model
GTM type
B2C
Offering type
Software
Cost components
Personnel, Technology or R&D, Infrastructure, Operations

Revenue model

  1. Public Government Funding: NCBI operates as a government-funded entity under the National Institutes of Health, supported by congressional appropriations and taxpayer funding. Services are provided free of charge to researchers, healthcare professionals, and the public worldwide.

Pricing tiers

ModelBillingPrice
FreemiumMonthlyFree public access to all databases and tools

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

NCBI product offering

Product offering

Core offering

NCBI provides free public access to authoritative biomedical and genomic databases, including PubMed for literature, GenBank for genetic sequences, and BLAST+ for sequence similarity search. It also offers computational biology tools and APIs that enable researchers, healthcare professionals, and students worldwide to conduct genomic analysis, literature searches, and comparative biology research at no cost.

Product overview

NCBI (National Center for Biotechnology Information) is a division of the National Library of Medicine at NIH that serves as a major international resource for biological and medical research data. NCBI provides access to a suite of databases, tools, and computational biology resources including PubMed, BLAST+, GenBank, and the Comparative Genomics Resource. The offering is a platform-plus-resources architecture where users access interconnected databases and analysis tools for genomic, biomedical, and bioinformatics research.

Differentiator

Problem solved

Functional benefit

Brands

  • PubMed: Free online database of biomedical literature citations and abstracts.
  • BLAST+
  • NCBI Bioinformatics Workflows
  • NCBI Databases

Products and services

  • PubMed A free search engine accessing the MEDLINE database of references and abstracts on life sciences and biomedical topics, maintained by NCBI for researchers, healthcare professionals, and the general public.
  • BLAST+ A bioinformatics tool for comparing gene or protein sequences against databases to find regions of similarity, used by researchers for identifying homologous sequences and functional annotation.
  • Comparative Genomics Resource An NCBI resource that facilitates comparative genomic analyses across species to understand evolutionary relationships and genomic conservation, targeted at computational biology researchers.
  • GenBank An annotated collection of publicly available DNA sequences maintained by NCBI, used by researchers worldwide for genomic and genetic sequence analysis.

Companies that use NCBI

Customer profile

Named customers2 records

Segments3 records

Ideal customer profiles3 records

NCBI technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature1 record

NCBI partnerships and signals

Strategic signal

Partnerships

One partnership is on record.

  • Accelerating Medicines Partnership (AMP)flagshipStrategic or Co-development Partner · 1 January 2014AMP is a public-private partnership between NIH, FDA, multiple biopharmaceutical and life science companies, and non-profit organizations to transform the current model for developing new diagnostics and treatments. NIH and AMP partners share expertise and resources to enable best-informed contributions to science. NCBI resources support AMP data infrastructure and research coordination.

Scale indicators2 records

Recent moves6 records

Expansion highlights6 records

NCBI competitors and assessment

Company assessment

Broad incumbents

  • Wellcome Sanger Institute: Sanger is a large, publicly funded genomics research institute that operates its own data platforms (e.g., COSMIC, Ensembl) and contributes heavily to shared genomic databases. It is comparable to NCBI as a publicly funded life-science data powerhouse but with a broader wet-lab research portfolio.
  • Broad Institute: The Broad Institute is a leading genomics and biomedical research organization that develops widely used tools (e.g., GATK) and hosts major datasets (e.g., gnomAD). It overlaps with NCBI in serving the computational genomics community and contributing to shared reference resources.
  • Allen Institute: The Allen Institute is a non-profit medical research organization producing large, openly available reference datasets (e.g., Allen Brain Atlas). It is comparable as a publicly minded, non-profit producer of high-value reference biological data.
  • Joint Genome Institute (JGI): JGI is a DOE-funded user facility for genomic sequencing and analysis, producing large-scale datasets that often flow into NCBI's archives. It is comparable as a publicly funded genomics data producer, though its focus is on energy and environmental applications.

Emerging players

  • DNAnexus: DNAnexus is a commercial cloud-based bioinformatics platform offering genomics data management and analysis for pharma, clinical, and research customers. It overlaps with NCBI in serving genomic data workflows but operates as a paid, enterprise SaaS rather than a free public resource.
  • Galaxy Project: Galaxy is an open, web-based platform for accessible genomic data analysis that integrates public datasets (including those from NCBI). It is comparable as a community bioinformatics resource, though its focus is on user-facing analysis workflows rather than primary data archiving.

Direct peers

  • Swiss Institute of Bioinformatics (SIB): SIB maintains widely used bioinformatics resources such as UniProt, STRING, and SWISS-MODEL. It is a publicly funded, non-profit bioinformatics infrastructure provider with a mission and operating model closely aligned to NCBI.
  • National Genomics Data Center (NGDC, China): NGDC operates a portfolio of open genomic databases (e.g., GSA, BIG) under the Chinese Academy of Sciences, serving as the primary national counterpart to NCBI/GenBank for genomic data submission, archiving, and analysis in China.
  • DNA Data Bank of Japan (DDBJ): DDBJ is one of the three founding partners (with GenBank and ENA) of the International Nucleotide Sequence Database Collaboration. It offers a directly comparable public genetic sequence repository for researchers in Asia and globally.
  • EMBL-EBI (European Bioinformatics Institute): EMBL-EBI is the European equivalent of NCBI, maintaining complementary biological databases (e.g., ENA, UniProt, Ensembl) under a public-good model funded by EMBL member states. It is NCBI's closest international partner and most direct peer in mission, scope, and user base.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat6 records

Key risks5 records

Key highlights6 records

Customer concentration

NCBI social profiles

Digital presence

NCBI financial estimates

Financial estimate

Revenue estimate

Valuation estimate

NCBI leadership team

Management profile

Number of profiles

Profiles1 record

NCBI subsidiaries and ownership

Company hierarchy

Subsidiaries27 records

NCBI funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

NCBI M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NCBI

What does NCBI do?

NCBI provides free public access to authoritative biomedical and genomic databases, including PubMed for literature, GenBank for genetic sequences, and BLAST+ for sequence similarity search. It also offers computational biology tools and APIs that enable researchers, healthcare professionals, and students worldwide to conduct genomic analysis, literature searches, and comparative biology research at no cost.

Is NCBI a public or private company?

NCBI is a public company. It is classified as state government owned and is currently operating.

When was NCBI founded?

NCBI was founded in 1887. It employs 251 to 500 people.

Where is NCBI based?

NCBI is headquartered in Bethesda, United States, in the North America region.

How does NCBI make money?

One revenue line is on record: public Government Funding.

Who are NCBI's main competitors?

Broad incumbents on record are Wellcome Sanger Institute, Broad Institute, Allen Institute and Joint Genome Institute (JGI). Emerging players are DNAnexus and Galaxy Project. Direct peers are Swiss Institute of Bioinformatics (SIB), National Genomics Data Center (NGDC, China), DNA Data Bank of Japan (DDBJ) and EMBL-EBI (European Bioinformatics Institute).

Does NCBI have an API?

No public API is recorded for NCBI.

What industry is NCBI in?

NCBI's product category is Bioinformatics databases and computational biology tools. Its primary akta.pro industry code is HLAAALAD, Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics), with a secondary code of HLAGAEAD, Genomics & Molecular Diagnostics (Trial Support). Its NAICS code is 5417 and its SIC code is 8731.

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Live signals
LinkedInNational Center for Biotechnology Information (NCBI)The article describes the National Center for Biotechnology Information (NCBI) as an entity established in 1988 by the US Congress under the National Institutes of Health. It serves as a major international resource for biological and medical research data, offering access to databases, tools, and research in computational biology.Analytics InsightBest Bioinformatics Tools for 2026The article reviews key bioinformatics tools anticipated to be prominent in 2026, including AlphaFold 3 from DeepMind, Galaxy Platform, BLAST+ from NCBI, GATK from the Broad Institute, QIIME 2, Cytoscape, and Snakemake.Aimed-AnalyticsThe Future of Bioinformatics: AI and Cloud ComputingA review by Xu-Kai Ma and colleagues outlines the future of bioinformatics software development, emphasizing the pivotal role of artificial intelligence and cloud computing in managing exponential biomedical data growth. The article highlights the importance of open science principles, such as FAIR guidelines, and tools like GitHub for collaboration, while noting past challenges with reproducibility in widely used software like NCBI BLAST+. It concludes by introducing a new AI-powered, cloud-based platform designed to make complex genomic analysis accessible to researchers without coding expertise.MantellassociatesThe Future of the Small Molecule MarketThe global Small Molecule API market was valued at USD 175.31 billion in 2021 and is projected to reach USD 282.50 billion by 2030, growing at a CAGR of 5.44%. The National Center for Biotechnology Information confirms that small molecules constitute 75% of FDA-approved drugs, with half of these approvals originating from small-to-mid-size companies utilizing CDMOs. This growth is driven by rising chronic disease prevalence and the continued dominance of small molecules over biologics in oncology and other therapeutic areas.GitHubGitHub - ncbi/blast_plus_docsThe article provides documentation for using the NCBI BLAST+ Docker image to run sequence analysis on Google Cloud Platform (GCP) and Amazon Web Services (AWS). It details the setup process for creating a virtual machine on GCP, including activating a $300 credit for new users, as well as step-by-step instructions for running BLAST analyses using Docker. This resource aids users in conducting reproducible bioinformatics analyses in the cloud.NatureHigh-coverage, long-read sequencing of Han Chinese trio reference samplesA single-molecule long-read sequencing dataset was generated for a Han Chinese son-father-mother trio using the Pacific Biosciences Sequel System. The data, including raw reads and alignments to GRCh37 and GRCh38 references, is publicly available via NCBI to support the development and evaluation of long-read bioinformatics methods.NatureHigh throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundariesResearchers developed FastANI, a novel algorithm that estimates Average Nucleotide Identity (ANI) using alignment-free approximate sequence mapping, achieving speedups of up to three orders of magnitude over traditional alignment-based methods. By analyzing 8 billion pairwise comparisons across 90,000 prokaryotic genomes in the NCBI database, the study confirms clear genetic discontinuity with distinct species boundaries defined by >95% intra-species and <83% inter-species ANI values.