Onyx Clinical Research Llc

What Onyx Clinical Research Llc does

Onyx Clinical Research LLC is a privately held, founder-led U.S. clinical research organization operating two physical sites — its original office in Flint, Michigan and a newer facility opened in October 2022 in Peoria, Arizona — to conduct and support clinical trials across 17 therapeutic areas including dermatology, cardiology, hepatology, gastroenterology, infectious diseases, immunology, nephrology, neurology, ophthalmology, orthopedics, pediatrics, pharmacology, pulmonology, rheumatology, urology, women's health, and vaccines. The company serves a tri-segment audience: individual patients recruited through community-led, direct-to-consumer engagement (website, blog, YouTube, Instagram, email newsletter, Google reviews); physicians and healthcare providers given a turnkey infrastructure (medical, legal, and regulatory backend) to run trials in-office or online through Onyx's physician network; and pharmaceutical sponsors and CROs seeking recruitment, enrollment, engagement, and retention support across diverse sites.

The underlying technology is described as a "completely tech-enabled" clinical research operations platform covering the full trial lifecycle from patient recruitment through retention, with an emphasis on integrating site and participant perspectives into trial design. The platform is supported by marketing assets including condition-specific educational content (atopic dermatitis, Crohn's disease, IgA nephropathy, lupus, ulcerative colitis, gout) and a dedicated YouTube channel. No proprietary AI/ML capabilities, patents, or third-party platform integrations are disclosed.

The business model is professional-services revenue from sponsored clinical trials — Onyx recruits participants, manages trial operations, and provides research services to pharmaceutical sponsors and CROs in exchange for site fees. Patient participants are reimbursed for time and travel on a per-study basis (amounts vary by protocol and are not publicly disclosed). The company does not disclose revenue, funding, or ownership structure beyond operating as an independent LLC with no parent company, no subsidiaries, and no disclosed institutional investment. Founder Sudeep Upadhye leads the organization, with medical-affairs support including Dr. Albert Cheng.

Name

Onyx Clinical Research Llc

Legal name

Onyx Clinical Research LLC

Website

https://onyxclinical.com

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

11–50 employees

Short description

Onyx Clinical Research LLC is a privately held U.S. clinical research organization operating two sites in Flint, MI and Peoria, AZ that recruits patients and engages physician networks to run clinical trials across 17 therapeutic areas for pharmaceutical sponsors and CROs.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Trial Site Operations & Study Coordination (HLAGACAE)

akta.pro secondary industries

Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Clinical CROs (Phase I–IV) (HLAGAAAA)

Keywords

• Clinical trial services
• Patient recruitment
• Clinical research sites
• Therapeutic area trials
• Site management organization

Headquarters

HQ city

Peoria

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. Clinical Trial Services: Revenue generated from conducting clinical trials for pharmaceutical sponsors and CROs. The company recruits participants, manages trial operations, and provides research services across multiple therapeutic areas including dermatology, cardiology, hepatology, gastroenterology, immunology, nephrology, neurology, ophthalmology, orthopedics, pediatrics, pharmacology, pulmonology, rheumatology, urology, women's health, and vaccines.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels6 records

Core offering

Onyx Clinical Research operates as a clinical trial site organization that recruits patients, coordinates physician investigators, and runs clinical trials on behalf of pharmaceutical sponsors and Contract Research Organizations (CROs). The company delivers end-to-end trial execution across 17 therapeutic areas including dermatology, cardiology, gastroenterology, immunology, nephrology, neurology, women's health, vaccines, and rheumatology, supported by a technology-enabled operations platform and a network of community physicians.

Product overview

Onyx Clinical Research LLC operates as a clinical research organization offering a comprehensive suite of clinical trial services. The company provides a technology-enabled platform that connects patients, physicians, and sponsors/CROs for clinical trial participation. Their portfolio includes core patient recruitment and enrollment services, a physician network enabling clinicians to conduct research, and specialized therapeutic area research programs covering Dermatology, Cardiology/Vascular Diseases, Gastroenterology, Immunology, Nephrology, Neurology, Women's Health, Vaccines, and Rheumatology. The company has two physical locations in Flint, MI and Peoria, AZ serving the clinical trial needs of sponsors, CROs, and participants.

Differentiator

Problem solved

Functional benefit

Products and services

• Clinical Trial Research Services

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Scale indicators1 record

Recent moves5 records

Expansion highlights4 records

Direct peers

• Flourish Research: Multi-site U.S. clinical research organization with therapeutic-area depth in cardiology, neurology, and dermatology; comparable to Onyx in community-based recruitment and site-network operations.
• Optimal Research: Multi-therapeutic clinical trial site network serving sponsors and CROs across dermatology, gastroenterology, vaccines, and women's health — closely aligned with Onyx's TA mix and site-based model.
• Velocity Clinical Research: Multi-site integrated clinical research organization operating numerous locations across the U.S., directly comparable to Onyx in business model (community-based site operations) and multi-therapeutic-area approach.
• CenExel: Network of clinical research sites across multiple therapeutic areas with deep CNS and specialty expertise; comparable as a multi-site, multi-TA clinical research operator.

Broad incumbents

• Medpace: Mid-sized global CRO with significant Phase II/III site network operations; comparable as a contract research organization serving sponsors in multiple therapeutic areas, though at meaningfully greater scale than Onyx.
• IQVIA: Largest global CRO and clinical research site operator with deep sponsor relationships across all therapeutic areas; serves as the benchmark incumbent against which smaller site networks like Onyx compete.
• ICON plc: Global CRO providing full-service clinical development including site management; relevant comparable for the sponsor-facing services Onyx sells, but operates at vastly greater scale and breadth.
• Syneos Health: Full-service biopharmaceutical solutions organization with clinical trial site operations across multiple TAs; comparable to Onyx in the services it sells to sponsors and CROs.

Regional players

• Benchmark Research: Regional U.S. clinical research site network focused on vaccines and infectious diseases; comparable to Onyx as a similarly scaled, multi-site clinical trial operator with community recruitment.

Others

• Acurian (Syneos Health patient recruitment): Patient recruitment and retention service provider to sponsors and CROs; comparable to Onyx's community-led patient recruitment capabilities, though typically functions as a vendor rather than a site operator.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat2 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/channel/UCc9AV6XScuVopz1wIUGwT_g
• LinkedInlinkedin.com/company/onyx-clinical-research
• Instagraminstagram.com/onyxclinicalarizona

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Onyx Clinical Research Llc