SPQI
SPQI (4BioDx) is a French biotech developing ELISA-based 4MID Kits and monoclonal antibodies that quantify the proAKAP4 sperm quality biomarker and Tau protein epitopes for veterinary, animal reproduction, and neuroscience research customers worldwide.
- Company typePrivate
- Founded2016
- HeadquartersLille, France
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What SPQI does
SPQI S.A.S, operating under the 4BioDx brand, is a French biotechnology company founded in June 2016 as a spin-off from Inserm laboratory UMRS1172 in collaboration with CHRU de Lille and the University of Lille. The company develops, produces, and commercializes laboratory reagents, ELISA-based diagnostic kits, and monoclonal/polyclonal antibodies for research use. Its flagship offering is the 4MID Kit family — sandwich ELISA kits that quantify the proAKAP4 biomarker in semen to objectively assess sperm quality and predict fertility. The portfolio addresses three customer segments: veterinary and animal reproduction (livestock breeding, equine centers, companion animals across pig, cat, horse, bull, mouse/rat, camel, and human applications), human male fertility research, and neuroscience research (notably Tau protein pathology via the anti-Tau pS422 monoclonal antibody).
SPQI firmographics
Firmographics- Name
- SPQI
- Legal name
- SPQI S.A.S
- Website
- https://4biodx.com
- Company type
- Private
- Founded year
- 2016
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- SPQI (4BioDx) is a French biotech developing ELISA-based 4MID Kits and monoclonal antibodies that quantify the proAKAP4 sperm quality biomarker and Tau protein epitopes for veterinary, animal reproduction, and neuroscience research customers worldwide.
- Ownership category
- akta.pro rank
SPQI industry classification
Industry- Product category
- Biotechnology Research Reagents
- NAICS
- In-Vitro Diagnostic Substance Manufacturing (325413)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Proteomics & Biomarker Analytical Testing (HLAGADAG)
- akta.pro secondary industry
- Reproductive & Endocrinology Diagnostics (Fertility, Hormones) (HLAMADAF)
Keywords
Where SPQI is headquartered
LocationHeadquarters
- HQ city
- Lille
- HQ country
- France
- HQ region
- Europe
Offices1 record
Markets served
SPQI business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Technology or R&D, Supply Chain, Marketing or Sales, Operations
Revenue model
- 4MID® Kits (ELISA): Sale of ELISA diagnostic kits for assessing sperm quality through proAKAP4 biomarker detection. Kits are available for multiple animal species (cat, mouse, rat, bull, pig, horse, camel) and are sold as research use only products.
- Monoclonal and Polyclonal Antibodies: Sale of research antibodies including anti-AKAP4, anti-proAKAP4, and anti-Tau antibodies for various research applications (Western Blot, IHC, IF, Flow Cytometry).
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | Anti-AKAP4 (clone 7E10) - 100µg |
| Unit Pricing | Pay-as-you-go | 4MID Kits promotional offers |
| Unit Pricing | Pay-as-you-go | Antibodies promotional discount |
Go-to-market motion2 records
Distribution channels6 records
Marketing channels5 records
SPQI product offering
Product offeringCore offering
SPQI (operating under the brand 4BioDx) develops, manufactures and commercializes sandwich ELISA kits (the 4MID® line) that measure the proAKAP4 biomarker in animal and human semen to objectively assess sperm quality and fertility, alongside a portfolio of monoclonal and polyclonal antibodies for reproductive biology and neurodegeneration research. Its products are sold as research-use-only reagents through its e-commerce site and a global distributor network serving veterinary clinics, breeding centers, andrology labs and academic research institutions.
Product overview
SPQI (4BioDx) is a biotechnology company offering a portfolio of ELISA-based diagnostic kits and antibodies for sperm quality assessment and neurodegenerative disease research. The core products include the 4MID Kit family (sandwich ELISA kits quantifying proAKAP4 biomarker in semen) available for multiple species (pig, cat, horse, bull, mouse/rat, camel), and a range of monoclonal/polyclonal antibodies including Anti-AKAP4, Anti-proAKAP4, and Anti-Tau pS422 antibodies. These products serve research institutions, veterinary diagnostic labs, and breeding facilities.
Differentiator
Problem solved
Functional benefit
Products and services
- 4MID Kits (ELISA family) Sandwich ELISA kits that quantify the proAKAP4 protein biomarker in semen to objectively assess sperm quality and male fertility. The family covers multiple species including pig, cat, horse, bull, mouse/rat and camel, and is sold for research use only to veterinary clinics, breeding centers, andrology labs and research institutions.
- Pig 4MID Kit (Ref. 4VDX-17K2) ELISA kit for quantifying proAKAP4 in pig semen to objectively evaluate semen quality, breeding male selection and traceability for swine AI centers and breeding programs.
- Cat 4MID Kit (Ref. 4VDX-19K10) ELISA kit with 0–150 ng detection range for quantifying proAKAP4 in cat/feline semen as a functional marker of sperm quality and fertility, aimed at feline breeding programs and reproductive research.
- Mouse/Rat 4MID Kit (Ref. 4BDX-18K8) ELISA kit for quantifying proAKAP4 in mouse, rat, hamster and guinea pig semen, used in preclinical, toxicological and experimental reproductive biology studies.
- Monoclonal Antibodies (research reagent line) Catalog of mouse monoclonal antibodies — Anti-AKAP4 (clone 7E10), Anti-proAKAP4 (clone 6F12) and Anti-Tau pS422 (clone 2H9) — for Western Blot, immunohistochemistry, immunofluorescence, flow cytometry, ELISA and electron microscopy applications in reproductive biology and neurodegeneration research.
- Anti-AKAP4 Antibody (clone 7E10, Ref. 4BDX-1602) Mouse monoclonal antibody targeting the carboxy-terminal region of AKAP4, validated for Western Blot, immunohistochemistry, immunofluorescence, ELISA, electron microscopy and flow cytometry. Priced at €289.00 for 100 µg.
- Anti-proAKAP4 Antibody (clone 6F12, Ref. 4BDX-1701) Mouse monoclonal antibody specific to the proAKAP4 precursor form of AKAP4, validated for Western Blot, immunofluorescence, immunohistochemistry and flow cytometry in reproductive biology research.
- Anti-Tau pS422 Antibody (clone 2H9, Ref. 4BDX-1501) Monoclonal antibody detecting the pathological phospho-epitope of Tau at Serine 422, used as a marker of neurofibrillary degeneration in Alzheimer's disease research, drug development and immunotherapy applications.
- Polyclonal Antibodies Polyclonal antibodies directed against phosphorylated forms of APP and other targets relevant to neurodegenerative disease research, used alongside the company's monoclonal reagents in academic and pharma research labs.
Quantifiable outcome
- ProAKAP4 concentration correlates with sperm motility and fertility rates in bulls, horses, pigs, and humans
- +2 more outcomes
Companies that use SPQI
Customer profileNamed customers6 records
Segments3 records
Ideal customer profiles3 records
SPQI technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
SPQI partnerships and signals
Strategic signalPartnerships
24 partnerships are on record, tiered regional and core.
- Inqaba Biotechnical Industries (Pty) LtdregionalDistributor for South Africa and Sub-Saharan Africa. All 4BioDx products available through this partner.
- Cosmo Bio USAcoreLong-standing partner since company inception. Distributes all 4BioDx products in North America (USA and Canada).
- Cosmo Bio CocoreMain distributor of 4BioDx products in Japan. One of the biggest distributors of laboratory reagents in Japan with 30+ years experience.
- BioScotia Technologies Inc.regionalNew partner for sale and promotion of 4BioDx products in Canada.
- Novis Animal SolutionsregionalProvides proAKAP4 analysis as fee-for-service in USA for companion animals.
- BioNovus Life ScienceregionalMain distributor of 4BioDx products in Australia.
- Li StarFishregionalDistributes 4BioDx products in Italy. Italian company in medical and veterinary research field.
- DiagenregionalMain distributor of 4BioDx products in Turkey since 2017. Also covers Uzbekistan, Kyrgyzstan, and Turkmenistan.
- GreenPureregionalDistributes all 4BioDx products in South Korea. Well-renowned Korean company in medical and veterinary research.
- Tsingmu Biotechnology (Wuhan) Co., Ltd (青木生物技术（武汉）有限公司)regionalDistributes 4BioDx products in China (area of animal reproduction).
- Beijing ALT Biotech Co., LtdregionalDistributes 4BioDx products in China.
- BiolinkkregionalPromotes and sells all 4BioDx products in India.
- Hölzel Diagnostika Handels GmbHregionalDistributes 4BioDx products in Germany, Austria, and Switzerland.
- BIOFAR LaboratorisregionalVeterinary diagnostic laboratory offering Pig 4MID Kit analysis for boar semen quality in Spain.
- Filgen, IncregionalDistributes 4BioDx products in Japan.
- Aloquence, spol. s r.o.regionalDistributes all 4BioDx products in Slovakia and Czech Republic.
- XL Biotec Co LtdregionalPromotes and sells 4BioDx products in Thailand.
- PT Afirmus Biotek IndonesiaregionalDistributes 4BioDx products in Indonesia.
- Scientific Hub Services (SHS)regionalPromotes and sells 4BioDx products in Singapore.
- EVRA TechnologiesregionalHas been commercializing 4MID Kits since 2017 in France.
- LNCR (Laboratoire National de Contrôle des Reproducteurs)regionalFrench national laboratory offering proAKAP4 analysis for pig, bull, small ruminants, and dog.
- ANIREPROregionalFrench company performing proAKAP4 analysis for canine semen at major veterinary hospitals in France.
- Calibre ScientificregionalGlobal distributor representing niche life science companies. Offers 4BioDx products through their platform.
- Linalux Mont-le-SoieregionalEuropean equine center in Belgium using 4MID Kit products to improve reproductive evaluation and breeding of horses.
Scale indicators2 records
Recent moves6 records
Expansion highlights6 records
SPQI competitors and assessment
Company assessmentBroad incumbents
- Zoetis: Global animal health leader offering diagnostics, vaccines, and reproductive tools across livestock and companion animals. Overlaps with SPQI on veterinary reproductive diagnostics and animal health research reagents, though as part of a far broader portfolio.
- Thermo Fisher Scientific: Dominant life-science tools and diagnostics company offering ELISA kits, antibodies, and biomarker assays through brands such as Invitrogen and Thermo Scientific. Directly comparable to SPQI's 4MID ELISA kits and monoclonal antibody catalog, but as a broad incumbent rather than a niche specialist.
- IDEXX Laboratories: Leading veterinary diagnostics company providing in-clinic lab tests and reference-lab services for companion animals and livestock. Comparable to SPQI as a veterinary diagnostics provider but operates at much larger scale and with regulated IVD assays rather than research-use kits.
- Bio-Rad Laboratories: Established life-science research and clinical diagnostics company with a sizable ELISA kit and antibody portfolio. Comparable to SPQI's biomarker detection kits and research antibodies, but operating at enterprise scale across many research areas.
Others
- Calibre Scientific: Global distributor representing niche life-science companies and selling research reagents and diagnostics through its platform; SPQI's products are already sold through Calibre Scientific. Comparable as a distribution channel and as a partner for niche reagent brands.
Direct peers
- Cell Signaling Technology: Premium research antibody company focused on validated reagents for signaling pathways and disease research, including phospho-specific Tau antibodies. Direct peer to SPQI's antibody catalog serving neuroscience and academic researchers globally.
- Santa Cruz Biotechnology: Research reagent supplier offering monoclonal and polyclonal antibodies across many research areas including neurodegeneration. Comparable to SPQI's antibody catalog as a research-use-only reagent provider with global e-commerce distribution.
- Abcam: Specialist research antibody vendor offering monoclonal and polyclonal antibodies for academic and pharma research, including neuroscience targets. Closely comparable to SPQI's monoclonal antibody business (anti-AKAP4, anti-proAKAP4, anti-Tau pS422) with similar research-use-only go-to-market.
- IMV Technologies: Specialist in animal reproduction equipment, semen analysis, and AI consumables serving livestock and equine markets globally. Comparable to SPQI's animal reproduction customer base and sperm-quality use case, with overlap in cryopreservation and AI-center workflows.
- Hamilton Thorne (Minitube): Animal reproduction technology company offering sperm analysis instruments, CASA systems, and AI consumables for livestock and research species. Comparable to SPQI as a provider of sperm quality assessment tools to AI centers and breeding facilities, but focused on hardware/CASA rather than biomarker ELISA.
Market position
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
SPQI social profiles
Digital presenceSPQI financial estimates
Financial estimateRevenue estimate
Valuation estimate
SPQI leadership team
Management profileNumber of profiles
Profiles3 records
SPQI funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
SPQI M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about SPQI
What does SPQI do?
SPQI (operating under the brand 4BioDx) develops, manufactures and commercializes sandwich ELISA kits (the 4MID® line) that measure the proAKAP4 biomarker in animal and human semen to objectively assess sperm quality and fertility, alongside a portfolio of monoclonal and polyclonal antibodies for reproductive biology and neurodegeneration research. Its products are sold as research-use-only reagents through its e-commerce site and a global distributor network serving veterinary clinics, breeding centers, andrology labs and academic research institutions.
Is SPQI a public or private company?
SPQI is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was SPQI founded?
SPQI was founded in 2016. It employs 1 to 10 people.
Where is SPQI based?
SPQI is headquartered in Lille, France, in the Europe region.
How does SPQI make money?
Two revenue lines are on record. 4MID® Kits (ELISA) is the primary driver. The others are monoclonal and Polyclonal Antibodies.
Who are SPQI's main competitors?
Broad incumbents on record are Zoetis, Thermo Fisher Scientific, IDEXX Laboratories and Bio-Rad Laboratories. Calibre Scientific is listed as an others. Direct peers are Cell Signaling Technology, Santa Cruz Biotechnology, Abcam, IMV Technologies and Hamilton Thorne (Minitube).
Does SPQI have an API?
No public API is recorded for SPQI.
What industry is SPQI in?
SPQI's product category is Biotechnology Research Reagents. Its primary akta.pro industry code is HLAGADAG, Proteomics & Biomarker Analytical Testing, with a secondary code of HLAMADAF, Reproductive & Endocrinology Diagnostics (Fertility, Hormones). Its NAICS code is 325413 and its SIC code is 2835.