eckert ziegler isotope products

What eckert ziegler isotope products does

Eckert & Ziegler Isotope Products (EZIP) is a US-headquartered manufacturer of sealed radioactive sources used primarily for quality control and calibration of nuclear medicine imaging systems, including PET, SPECT, SPECT/CT, PET/CT, and PET/MR modalities. Founded in 1967 as Isotope Products Laboratories (IPL) and now operating as a division of publicly listed German parent Eckert & Ziegler SE, the company is headquartered in Valencia, California, with 9,000+ sqm of laboratory and storage space and sales in 60 countries. The product portfolio spans Co-57 flood sources (FeatherLite, Perflexion, C-Thru variants), PET sources (Ge-68 and Na-22 line sources, spot markers, and QC phantoms), SPECT sources (Co-57 calibration sources, xSPECT Quant kits, Gd-153 line sources), multimodal fiducial markers (MMS series) for hybrid image coregistration, and accessories and shielding solutions. EZIP holds ISO 9001, ISO 13485, ISO 17025 (DAkkS), EU MDR, and FDA certifications, and operates an in-house ISO 2919 capsule testing laboratory enabling Special Form Certificates and Sealed Source and Device Registrations.

The company is the only OEM-qualified manufacturer for all major medical imaging equipment OEMs, including Siemens Healthineers, GE Healthcare, Philips, Canon Medical Systems, United Imaging, and Spectrum Dynamics Medical, and is the sole GE-approved supplier of Discovery IQ PET/CT QC phantoms. It serves two primary customer segments: OEM medical imaging equipment manufacturers (which receive custom-integrated source solutions) and hospital and healthcare-system nuclear medicine departments (which use the sources for routine gamma camera, PET, and SPECT calibration and quality control). A one-for-one exchange program for depleted sources provides a recurring relationship layer on top of one-time product sales. Revenue is generated through direct enterprise sales with custom quote-based pricing, products shipped F.O.B. from California facilities, with most sources stocked and available to ship within five business days.

EZIP has executed a sustained roll-up acquisition strategy since 1999, adding capabilities in cesium isotopes (Cesio, 1999), the foundational DuPont Source Business (2001), calibration and analytics (CNL Scientific Resources, IPE, Analytics Inc., 2003-2005), European manufacturing (North American Scientifics 2007, nuclitec GmbH 2009), distribution (Chemotrade 2011), and Latin American expansion (REM Nuclear Brazil 2013, Gamma Service Group 2017, Tecnonuclear Argentina 2021). Regional subsidiaries operate in Germany (Braunschweig), France (Courtaboeuf), Brazil (São Paulo), and Argentina (Buenos Aires). The most recent disclosed strategic action is the January 2026 global availability announcement of Gd-153 line sources for Siemens Healthineers Auto QC, resuming supply after an October 2024 interruption.

Name

eckert ziegler isotope products

Legal name

Eckert & Ziegler Isotope Products

Website

https://isotopeproducts.com

Company type

Private

Founded year

1967

Operating status

Operating

Short description

Eckert & Ziegler Isotope Products manufactures sealed radioactive quality control sources for nuclear medicine imaging systems (PET, SPECT, PET/CT, SPECT/CT, PET/MR), serving as the sole OEM-qualified supplier for all major scanner manufacturers and thousands of hospital nuclear medicine departments across 60 countries.

Ownership category

akta.pro rank

Product category

Medical Imaging Quality Control Sources

NAICS

Irradiation Apparatus Manufacturing (334517)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Nuclear Medicine Imaging Tracers & PET/SPECT Supply Chain (FDG, Ga-68, logistics/cold chain) (EUAKAIAE)

akta.pro secondary industries

Industrial Isotope Production & Supply (Co-60, Ir-192, Cs-137, Am-241, etc.) (EUAKAIAB), Nuclear Materials Testing, Assay & Characterization Services (NDA/NDE, radiochemistry, materials analysis) (EUAKAIAL), Radioisotope Production (Reactor/Cyclotron/Gamma) (HLAIAGAD)

Keywords

• Sealed radioactive sources
• Nuclear medicine imaging
• Quality control sources
• Medical imaging isotopes
• Radiation calibration sources

Headquarters

HQ city

Valencia

HQ country

United States

HQ region

North America

Offices8 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Radioactive Source Products: Sale of sealed radiation sources for medical imaging including PET, SPECT, SPECT/CT, PET/CT, PET/MR modalities. Sources include Co-57 flood sources, line sources, point sources, and specialty calibration sources. Revenue is generated through one-time product sales with an associated one-for-one exchange program for returning depleted sources.
2. Accessories and Shielding: Sale of complementary products including ProKase storage cases, flood source shields, Perflexion shield tubes, carrying cases, Pb shippers for returns, and phantom shields. These products support the use and handling of radioactive sources.
3. Medical Imaging Accessories: Sale of accessory products including E-Vials (dose calibrator reference sources), pen point markers, spot markers, flexible markers, flexible rulers, rigid rulers, test tube sources, and rod sources for use in nuclear medicine and SPECT studies.

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels5 records

Core offering

Eckert & Ziegler Isotope Products (EZIP) manufactures and supplies sealed radioactive quality control sources used to calibrate, test, and verify the performance of nuclear medicine imaging systems, including PET, SPECT, SPECT/CT, PET/CT, and PET/MR scanners. The portfolio spans Co-57 flood sources (FeatherLite, Perflexion, C-Thru variants), Ge-68/Na-22 PET sources, Gd-153 line sources for Siemens SPECT/CT, xSPECT Quant calibration kits, multimodal fiducial markers (MMS series), complementary accessories (markers, rulers, vials, rods), and source shielding/transport cases. The company sells these manufactured products to hospital nuclear medicine departments worldwide and as OEM-qualified supplies to major imaging equipment manufacturers.

Product overview

Eckert & Ziegler Isotope Products (EZIP) is a global provider of sealed radioactive sources for nuclear medicine and industrial applications. The product portfolio centers on Quality Control Sources, specifically Co-57 Flood Sources available in three variants: FeatherLite (lightweight, up to 60% lighter), Perflexion (patented flexible design), and C-Thru (transparent PETG holder). The company also manufactures PET sources (including Ge-68 and Na-22 spot markers and line sources for Siemens Biograph, GE, United Imaging, and Philips systems), SPECT sources (Co-57 calibration sources, xSPECT Quant calibration/peak source kits, and Gd-153 line sources for Siemens Healthineers Auto QC), and multimodal fiducial markers (MMS01-MMS15 models for image coregistration). Supporting products include accessories (E Vials, pen point markers, spot markers, flexible and rigid rulers, test tube sources, rod sources) and source shielding solutions (ProKase, Perflexion Shield Tube, Flood Source Carrying Case, Pb Shipper, Phantom Shield). The company is ISO 9001 and ISO 13485 certified with DAkkS ISO 17025 accreditation, FDA registered, and EU MDR compliant.

Differentiator

Problem solved

Functional benefit

Brands

• FeatherLite: Lightweight Co-57 flood source weighing up to 60% less than other rigid flood sources, featuring inactive border protection for safer handling.
• Perflexion
• C-Thru
• ProKase

Products and services

• Co-57 Flood Sources Uniform Co-57 sealed flood sources used for daily quality control of gamma cameras in nuclear medicine. Available in three patented variants (FeatherLite, Perflexion, C-Thru) covering flexible, lightweight, and transparent-holder designs, all guaranteed to deliver a coefficient of variation (CV) of 0.8% or lower. For hospital nuclear medicine departments and OEM imaging equipment manufacturers.
• Co-57 Calibration Sources Calibration sources for SPECT systems, including Co-57 QC Rods tailored for Spectrum Dynamics D-Spect and Veriton cameras. Used by hospitals and OEM partners for system calibration and quality assurance.
• xSPECT Quant Calibration/Peaking Source Kits Calibration kits for Siemens xSPECT systems consisting of precision calibration source, shield, dose calibrator source holder, and peaking source. Available with Co-57, Se-75, or Sn-113 isotopes. NIST traceable with +/- 3% activity accuracy, enabling standardization of uptake values across different cameras, dose calibrators, and facilities.
• Gd-153 Line Sources Line sources for Siemens Healthineers Symbia Intevo and Pro.specta SPECT/CT scanners supporting Auto QC workflows for head alignment calibration, verification, and extrinsic sweep verification. Available in 10 mCi and 20 mCi configurations.
• PET QC Phantoms for Discovery IQ PET/CT Custom-designed imaging phantoms exclusively for the GE Discovery IQ PET/CT system, used for accurate calibration of PET detectors and quality control. EZIP is the only GE-approved supplier for Discovery IQ QC phantoms.
• PET Line Sources and Spot Markers Ge-68 and Na-22 PET line sources (transmission rods, normalization pins, rod sources) and Na-22/Ge-68 spot markers in standard nominal activities (10 uCi or 100 uCi) for all major PET modality systems, including Philips Gemini PET/CT scanners. Used for PET transmission scanning and normalization.
• MMS Multimodal Fiducial Marker Series Multimodal fiducial markers (MMS01, MMS02, MMS05, MMS09, MMS11 models) for hybrid PET/CT, SPECT/CT, and PET/MR image coregistration. Include CT-visible bone-equivalent rings and trimodal (MR/CT/radionuclide) markers. Specific models are dedicated to Philips PET scanners (MMS05), Siemens Inveon (MMS11), and NEMA NU4 resolution testing (MMS09).
• Nuclear Medicine Accessories Accessory products including E-Vials (dose calibrator reference sources, NIST traceable within +/- 5%), pen point markers, spot markers, flexible markers, flexible rulers, rigid rulers, test tube sources, and rod sources for use in nuclear medicine and SPECT studies. Markers and rulers support region-of-interest marking and anatomical outlining on patients.
• Source Shielding and Storage Products Shielding and storage solutions for radioactive sources including ProKase portable storage case with swivel wheels, Perflexion flood source shields, tungsten shield tubes, flood source carrying cases, Pb Shipper DOT Type-A certified lead-lined shipping boxes for depleted source returns, and phantom shields for Ge-68 phantoms.

Quantifiable outcome

• CV of 0.8% or lower guaranteed on all flood sources
• +3 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Six partnerships are on record, tiered core.

• Siemens HealthineerscoreOEM/ Whitelabel/ Licensing PartnerOEM-qualified supplier of Quality Control Sources for Siemens Healthineers SPECT/CT scanners. Provides Gd-153 line sources for Auto QC feature for Symbia Intevo and Pro.specta systems, as well as Co-57 calibration sources for Siemens Symbia Auto QC systems. Two configurations available: 10 mCi (HEGL-0133) and 20 mCi (HEGL-0151) Gd-153 line sources.
• GE HealthcarecoreOEM/ Whitelabel/ Licensing PartnerOEM partner providing QC phantoms and sources for Discovery IQ PET/CT systems. EZIP is the ONLY GE-approved supplier for Discovery IQ QC phantoms. Also provides sources for various GE PET systems.
• Philips HealthcarecoreOEM/ Whitelabel/ Licensing PartnerOEM partner providing dedicated sources for Philips PET and PET/CT scanners including MMS05 trimodal fiducial marker. Also provides specialized sources for Philips Brightview XCT systems.
• Canon Medical SystemscoreOEM/ Whitelabel/ Licensing PartnerCustomer for nuclear medicine sources used in Canon Medical Systems imaging equipment. Source solutions tailored to Canon scanner specifications.
• United ImagingcoreOEM/ Whitelabel/ Licensing PartnerOEM partner providing phantom and transmission rod sources for United Imaging uMI 550 and uMI 780 full body PET/CT systems. Custom phantom and transmission rod sources available for United Imaging scanners.
• Spectrum Dynamics MedicalcoreOEM/ Whitelabel/ Licensing PartnerOEM partner providing Co-57 calibration sources and QC Rods for Spectrum Dynamics D-Spect and Veriton cameras.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• Curium Pharma: Curium Pharma is a major radiopharmaceutical manufacturer focused on diagnostic and therapeutic nuclear medicine products. While not a direct competitor in QC sources, Curium overlaps with EZIP's parent (EZAG SE) in the broader nuclear medicine supply chain and competes in adjacent sealed-source segments.
• SPECTRAL Instruments: Spectral Instruments manufactures preclinical and nuclear medicine imaging systems and related calibration tools. Its gamma camera and imaging systems overlap with EZIP's customer base in the preclinical and OEM imaging segment.
• Berthold Technologies: Berthold Technologies manufactures radiation measurement, detection, and calibration equipment for nuclear medicine, industry, and research. Its calibration sources and phantoms partially overlap with EZIP's QC source portfolio, particularly for non-OEM hospital customers.

Others

• GE Healthcare: GE Healthcare is both a key OEM customer (Discovery IQ PET/CT) and a broad incumbent in medical imaging equipment. Its nuclear medicine division competes at the scanner level and qualifies EZIP as an approved source supplier, making it both peer and customer.
• Canon Medical Systems: Canon Medical Systems is an OEM customer for nuclear medicine scanners and a broad incumbent in diagnostic imaging equipment. EZIP provides tailored source solutions for Canon PET and SPECT platforms.
• Siemens Healthineers: Siemens Healthineers is a core OEM customer (Symbia, Biograph, xSPECT product lines) and a broad incumbent in nuclear medicine imaging. Its PET and SPECT/CT scanner platforms drive demand for EZIP's Gd-153 line sources and Co-57 calibration sources.
• Philips Healthcare: Philips Healthcare is an OEM customer for PET and PET/CT scanners (Brightview, Gemini) and a broad incumbent in diagnostic imaging. EZIP supplies dedicated multimodal sources (MMS05) and Na-22 spot markers to Philips nuclear medicine platforms.
• Gamma Service Group: Gamma Service Group (now part of Eckert & Ziegler following the 2017 acquisition) provides service and support for sealed radioactive sources. As a sister company within the parent group, it represents an adjacent ecosystem participant rather than an external competitor.

Broad incumbents

• Mirion Technologies: Mirion Technologies is a broad incumbent in radiation detection, measurement, and sealed source manufacturing across medical, industrial, and security end markets. Their medical imaging QC source portfolio overlaps with EZIP's Co-57 and calibration product lines, though Mirion is a much larger diversified player.

Direct peers

• Curiem: Curiem (formerly RadQual) is the most direct peer, manufacturing sealed radioactive sources including Co-57 flood sources and calibration sources for nuclear medicine imaging QC — overlapping product categories and serving the same hospital and OEM customer base as EZIP.

Market position

Strengths5 records

Weaknesses4 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/showcase/eckert-&-ziegler-isotope-products

Compliance6 records

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries10 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

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