What picometrics technologies does

Picometrics Technologies, operating commercially as Adelis, is a French private analytical instrumentation company founded in 1999 (legal entity Adelis SAS, headquartered in Grabels, France, SIREN 792 207 599) with a wholly-owned US subsidiary Picometrics, Inc. in Cambridge, MA. The company designs and manufactures capillary electrophoresis platforms and laser/LED-induced fluorescence detectors for high-sensitivity DNA and RNA analysis. Its core technology is the patented μLAS (micro Laboratory for Analysis and Separation of DNA) platform, which uniquely combines hydrodynamic and electrokinetic actuation to concentrate, separate and purify DNA fragments in a single step—eliminating the extraction and sequential workflow required by classical cfDNA protocols and achieving limits of detection down to 1 fg/µL across a size range up to 100+ kbp.

The product portfolio is organized platform-plus-modules: two instrument families (Multi Channel BIABooster and Multi Channel CE), a plugin (BIABooster CE Pack) for Agilent 7100 CE systems, the Zetalif LED/laser detector family, dedicated analytical kits (DNA 1K, DNA 10K, DNA 100K, cfDNA, RNA 10K), proprietary BIABooster Analytics software, and a Smart Fragmentomics workflow for extraction-free cfDNA profiling from 50 µL of plasma. Revenue comes from instrument and consumable sales, contract DNA analysis services (mail-in samples), custom method development and OEM/white-label integration projects; pricing is quote-based for instruments and pay-as-you-go for analytical services, with no public price lists. Distribution is direct (field sales) globally across Europe, North America and Asia, complemented by Agilent channel integration.

Customers span major pharmaceutical and biotech companies (Boehringer Ingelheim, GSK, Janssen, Takeda, Merck, Regeneron, Loba Biotech, OM Pharma, Symphogen), academic medical centers and cancer hospitals (Gustave Roussy, AP-HP, CRCT), government and regulatory bodies (NIH, FDA, CNRS, Inserm), leading universities (MIT, Tsinghua, Charles University, Paris-Saclay, Université de Montpellier, Université de Liège) and clinical/research partners (EFS Lille/Marseille, APHM, ID Solutions Oncology, INRIA-COMPO, IGH, JEA). The company is founder-influenced under Chairman & CEO Philippe Pourquier (since 2018), founder/COO Jean-Charles Garcia and CTO Frédéric Ginot, and is active in scientific publishing, conference sponsorship and clinical study consortia targeting liquid biopsy, immunotherapy monitoring and transplant rejection.

Name

picometrics technologies

Legal name

SAS Jean-Charles Garcia, COO of Adelis

Website

https://picometrics.com

Company type

Private

Founded year

1999

Operating status

Operating

Short description

French private analytical instrumentation firm (Adelis SAS, founded 1999) that builds patented μLAS-based capillary electrophoresis instruments and ultra-sensitive LIF detectors for cfDNA, DNA and RNA analysis, selling to pharma, research institutes and universities globally.

Ownership category

akta.pro rank

Product category

Analytical Instrumentation

NAICS

Analytical Laboratory Instrument Manufacturing (334516), In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

Laboratory Analytical Instruments (3826), In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Analytical Instruments & Chromatography Systems (HLAGAIAA)

akta.pro secondary industry

Mass Spectrometry & Spectroscopy Instruments (HLAGAIAB)

Keywords

• Capillary electrophoresis instruments
• DNA analysis systems
• Fluorescence detection technology
• Liquid biopsy analytics
• Analytical chromatography detectors

Headquarters

HQ city

Grabels

HQ country

France

HQ region

Europe

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Analytical Instruments Sales: Sale of Multi Channel BIABooster and Multi Channel CE analytical platforms along with BIABooster CE Pack plugins for commercial capillary electrophoresis instruments. Instruments are sold directly to pharmaceutical companies, research institutes, universities, and quality control laboratories. Includes proprietary capillary cassettes and complete analytical systems.
2. Consumables and Kits: Sale of analytical kits including DNA 1K, DNA 10K, DNA 100K, cfDNA, and RNA 10K kits. These kits contain reagents, standards, and consumables for specific DNA/RNA size analysis applications. Kits designed for specific size ranges (0.1-1.5 kbp, 1-10 kbp, 1-100 kbp) and sample types (purified DNA, plasma).
3. DNA Analysis Services: Provides cfDNA and DNA analysis services using BIABooster technology with 100-1000x gain of sensitivity compared to best electrophoresis methods. Customers send plasma samples or purified DNA and receive comprehensive reports including quantified concentration and size distribution. Fast, easy, and affordable access to technology as a service.
4. Custom Method Development and Training: Tailor-made analytical methods development based on experience in glycans, antibodies, amino acids, and nucleic acids applications. Consulting services for sample processing and training on CE-LIF systems including labeling processes and analytical methods.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

Picometrics Technologies (Adelis) manufactures and sells analytical chromatography and capillary electrophoresis instruments based on its proprietary μLAS technology. Its BIABooster platform performs simultaneous concentration, separation, and purification of DNA fragments in a single inline step, enabling ultra-sensitive cfDNA analysis from as little as 50 μL of plasma without DNA extraction. The company complements these instruments with Zetalif fluorescence detectors, application-specific analytical kits, and outsourced DNA analysis services targeted at pharmaceutical, biotech, clinical-research, and academic customers.

Product overview

Picometrics Technologies (operating as Adelis) offers a platform-plus-modules architecture centered on the BIABooster analytical system. The core µLAS technology provides simultaneous DNA concentration and separation through dual hydrodynamic and electrokinetic actuation. The product portfolio comprises two main instrument lines: the Multi Channel BIABooster and Multi Channel CE platforms for high-sensitivity DNA/RNA analysis, supplemented by the BIABooster CE Pack for integration with commercial CE instruments. Supporting hardware includes Zetalif LED and Laser fluorescence detectors offering up to 100,000x greater sensitivity than UV detection. A comprehensive range of analytical kits (DNA 1K, DNA 10K, DNA 100K, cfDNA, RNA 10K) serve different size ranges and sample types. Services include DNA analysis outsourcing and custom method development. The ecosystem is tied together by BIABooster Analytics software and enables Smart Fragmentomics for liquid biopsy applications.

Differentiator

Problem solved

Functional benefit

Brands

• BIABooster: Multi-channel capillary electrophoresis platform for DNA and RNA analysis with ultra-sensitive detection capabilities
• Multi Channel CE
• Zetalif Detectors
• μLAS Technology
• BIABooster Kits

Products and services

• Multi Channel BIABooster Four-channel capillary electrophoresis instrument designed for DNA and RNA analysis using BIABooster/μLAS technology, featuring detection down to 1 fg/μL and size range up to 100+ kbp. Targeted at pharmaceutical R&D, biotech, and clinical-research laboratories needing ultra-sensitive cfDNA analysis.
• Multi Channel CE Versatile four-channel capillary electrophoresis instrument equipped with LEDIF detection, enabling parallel processing of 4 samples with robotic fluid handling and support for multiple CE modes (CZE, CGE, MEKC, CEC, CITP, TDA). Suited to biopharmaceutical QC and analytical-development labs.
• BIABooster CE Pack Plugin module for commercial capillary electrophoresis instruments (Agilent 7100 CE) that brings BIABooster inline DNA concentration and separation with automated analytical methods. Allows existing CE users to upgrade to high-sensitivity cfDNA workflows.
• Zetalif LED Detector Ultra-sensitive LED-induced fluorescence detector offering 10-100x greater sensitivity than conventional fluorescence and up to 100,000x more than UV detection, with wavelengths from 275-640 nm for various biomolecule applications. Integrates with capillary electrophoresis and HPLC systems.
• Zetalif Laser Detector Ultra-sensitive laser-induced fluorescence detector for HPLC, fast-LC, and CE systems with excitation wavelengths from 266 nm to 785 nm, enabling the highest-sensitivity detection of labeled biomolecules.
• DNA 1K Kit DNA sizing kit for analysis of purified DNA in the 0.1-1.5 kbp size range with LOD of 10 pg/mL at 1 kbp, designed for use with BIABooster CE or Multi Channel BIABooster platforms.
• DNA 10K Kit DNA sizing kit for analysis of purified DNA in the 1-10 kbp size range with LOD of 10 pg/mL at 10 kbp, designed for use with the BIABooster CE platform.
• DNA 100K Kit DNA sizing kit for analysis of genomic DNA up to 100 kbp size range with LOD of 50 pg/mL at 100 kbp, designed for use with the Multi Channel BIABooster platform.
• cfDNA Kit Cell-free DNA analysis kit for direct plasma analysis in the 0.1-1.5 kbp size range with LOD of 5 pg/mL at 1 kb, enabling extraction-free cfDNA analysis from biological fluids using BIABooster platforms.
• RNA 10K Kit Capillary electrophoresis kit for RNA analysis offering resolution up to 13 kb with LOD of 30 pg/μL, compatible with any CE instrument and the Multi Channel platforms.
• DNA Analysis Services Mail-in DNA analysis service using BIABooster technology providing 100-1,000x sensitivity gain compared to standard electrophoresis methods, including comprehensive reports with concentration and size distribution analysis. Customers send plasma or purified DNA samples to Adelis's technical laboratory in Labège.
• Analytical Methods Customization Custom analytical method development and consulting services for glycans, antibodies, amino acids, and nucleic acids applications, including training on CE-LIF systems covering labeling processes and analytical methods.
• BIABooster Analytics Software Proprietary software that converts raw fluorescence data into concentration distribution according to DNA size, featuring automation, QC experiments, sample comparisons, data export, and reporting capabilities. Bundled with BIABooster analytical platforms.

Quantifiable outcome

• 100-1000x sensitivity gain compared to best electrophoresis methods
• +5 more outcomes

Named customers27 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration6 records

Feature5 records

Partnerships

Eight partnerships are on record, tiered core.

• APHM (Assistance Publique - Hôpitaux de Marseille)coreStrategic or Co-development PartnerClinical study partner in SChISM (Size cfDNA Immunotherapies Signature Monitoring) study evaluating cfDNA for predicting patient response to immunotherapy treatments and longitudinal therapy response monitoring.
• EFS Lille (Établissement Français du Sang)coreStrategic or Co-development PartnerPartner in DIAL (DNA size baseline) study establishing typical cfDNA profile (concentration and size distribution) in healthy subjects regardless of age, sex, morphology, or mass index.
• EFS Marseille (Établissement Français du Sang)coreStrategic or Co-development PartnerPartner in LARA study to identify and validate new biomarkers in cfDNA to predict acute cellular rejection in lung transplant patients. Also partner in DIAL study.
• ID Solutions OncologycoreStrategic or Co-development PartnerPartner in SChISM clinical study and DIAL study for oncology applications of cfDNA analysis using BIABooster platform.
• INRIA-COMPOcoreStrategic or Co-development PartnerResearch partner in SChISM clinical study for immunotherapy response monitoring using cfDNA analysis.
• Gustave Roussy Cancer CentercoreStrategic or Co-development PartnerMajor French cancer research center and sponsor of 2nd Gustave Roussy Liquid Biopsy Symposium Paris 2026. Adelis sponsored the event featuring experts in cfDNA fragmentomics, MRD monitoring, and precision oncology.
• CRCT (Cancer Research Center of Toulouse)coreStrategic or Co-development PartnerPartner in organizing Innovation in Liquid Biopsy and Fragmentomics seminar (November 2025) showcasing latest developments in cfDNA analysis.
• Agilent TechnologiescoreTechnology or IntegrationInterface partnership with Agilent 7100 CE system for BIABooster CE Pack integration. The BIABooster capillary device cassette fits the Agilent CE7100 instrument and Zetalif detectors for full automation.

Scale indicators2 records

Recent moves7 records

Expansion highlights7 records

Direct peers

• Agilent Technologies: Agilent is a leading manufacturer of capillary electrophoresis systems (7100 CE) and a broad analytical instrument portfolio. Adelis's BIABooster CE Pack integrates directly with the Agilent 7100 CE, positioning Agilent as both a partner and the most direct competitive reference point in the CE market.
• Prince Technologies (PrinCE): Prince Technologies manufactures PrinCE Next capillary electrophoresis instruments. Adelis Zetalif detectors integrate with PrinCE Next systems, making PrinCE a direct CE platform peer and integration partner for fluorescence-based detection.
• WynSep: WynSep develops the Wyn-CE capillary electrophoresis platform. Adelis Zetalif detectors are compatible with WynSep Wyn-CE, making WynSep a niche CE instrument peer and integration partner.

Broad incumbents

• Thermo Fisher Scientific: Thermo Fisher is a dominant life sciences instrumentation company offering CE, HPLC, and analytical instruments across pharma, biotech, and clinical markets. It is a broad incumbent with overlapping analytical instrument capabilities relevant to Adelis's DNA analysis customers.
• Bio-Rad Laboratories: Bio-Rad manufactures capillary electrophoresis systems (BioFocus, Experion) and a broad life science research instrument portfolio. It serves pharma QC, research, and clinical diagnostics customers with overlapping analytical instrument offerings to Adelis.
• SCIEX (Danaher): SCIEX, part of Danaher, produces capillary electrophoresis and mass spectrometry systems for biopharma and academic research. Its CE-LIF-MS workflows directly overlap with Adelis's HPLC/CE-LIF product positioning.
• Beckman Coulter (Danaher): Beckman Coulter, owned by Danaher, is a long-established manufacturer of capillary electrophoresis instruments (PA 800 Plus, MDQ) for biopharmaceutical characterization and clinical diagnostics. It is a broad incumbent CE peer.
• PerkinElmer: PerkinElmer offers a broad analytical instrument portfolio including chromatography and detection systems for life sciences and diagnostics. Its fluorescence detection capabilities overlap with Adelis's Zetalif detector products.
• Shimadzu: Shimadzu manufactures HPLC, UHPLC, and analytical instruments for pharmaceutical and biotech markets. It is a broad incumbent in the liquid chromatography and detection space where Adelis's Zetalif detectors compete.
• Hitachi High-Tech: Hitachi High-Tech produces capillary electrophoresis systems (e.g., DS3000) and analytical instruments for genomics and biotech. It is a broad incumbent in the CE instrument market overlapping with Adelis's BIABooster platform.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/picometrics-s-a

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about picometrics technologies