cristiana bio tech

What cristiana bio tech does

Cristiana Bio Tech is a privately held Romanian biotechnology company founded in 2006 in Bucharest by Nicolae Nicolescu and Ion Nicolescu. The business operates two intertwined lines: the distribution of Hilotherm hilotherapy medical devices (Professional, HomeCare, and ChemoCare units, plus anatomical cuffs and service kits) to Romanian hospitals, private clinics, and specialty practices; and an in-house biotechnology research capability housed in a Bucharest R&D facility with ISO-certified cleanrooms, chromatography units, and real-time spectrophotometry. The research arm is built around four pillars — cloud-native machine-learning molecular modeling, lipid nanoparticle (LNP) matrix technology for targeted molecular delivery, customized enzymatic bio-catalysis for circular chemical recycling, and clinical pipeline development.

The company's go-to-market is a B2B enterprise field sales motion targeting Romanian healthcare providers, supplemented by event-driven demand generation through clinical workshops, product demonstration days, and medical conferences such as the KLS Martin CMF Symposium. Pricing is quote-based with no public list, and revenue is generated from one-time hardware sales, recurring service plans, training, and consumables (cuffs and accessories) on the medical device side, and managed R&D services on the biotechnology side. Core partnerships include the long-standing exclusive distribution relationship with Hilotherm, a collaboration with KLS Martin Group for craniomaxillofacial surgery products and events, and a historical relationship anchored in the Alpha Bio dental implant heritage.

The company peaked in 2019 with over 15 specialists nationwide and record turnover, then contracted to a 5-person core team. In 2024, the founders announced a strategic pivot toward higher-value medical and life-science biotechnology. The company is bootstrapped with no disclosed external funding, ownership is concentrated between the two co-founders, and operations are exclusively domestic to Romania.

Name

cristiana bio tech

Legal name

Cristiana Bio Tech

Website

https://cdbiotech.ro

Company type

Private

Founded year

2006

Operating status

Operating

Short description

Cristiana Bio Tech is a privately held Romanian biotechnology company founded in 2006 that distributes the Hilotherm hilotherapy medical device line to Romanian hospitals and specialty clinics while operating a Bucharest-based R&D facility focused on molecular modeling, lipid nanoparticle delivery, and bio-catalysis.

Ownership category

akta.pro rank

Product category

Medical Device Distribution and Biotechnology Research Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Preclinical CROs (Discovery/Pharmacology/DMPK) (HLAGAAAB)

akta.pro secondary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

Keywords

• Medical device distribution
• Hilotherapy equipment
• Biotechnology research services
• Molecular modeling
• Post-operative cold therapy

Headquarters

HQ city

Bucharest

HQ country

Romania

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Supply Chain, Personnel, Marketing or Sales, Technology or R&D, Infrastructure, Operations

Revenue model

1. Hilotherapy Medical Device Sales: Distribution and sales of Hilotherm hilotherapy devices (Professional, HomeCare, ChemoCare) and accessories (cuffs, service kits) to Romanian healthcare providers. One-time hardware sales with associated consumables and service plans.
2. Service Plans & Training: Service plans, clinical training, and support services for medical staff using hilotherapy equipment. Ongoing revenue from service contracts and spare parts.
3. Biotechnology R&D Services: Research and development services in computational bio, sustainable innovation, and health/life sciences for partners and clients.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels6 records

Core offering

Cristiana Bio Tech distributes the Hilotherm hilotherapy medical device family (Professional, HomeCare, ChemoCare) and accessories to Romanian healthcare providers, and conducts in-house biotechnology R&D at its ISO-certified Bucharest facility. Its research spans cloud-native ML molecular modeling, lipid nanoparticle (LNP) targeted delivery matrices, and bio-catalysis for circular chemical recycling, offered as services to partners alongside clinical product distribution.

Product overview

Cristiana Bio Tech operates as a biotechnology company distributing medical devices and related products, primarily the Hilotherm hilotherapy product line, alongside biotechnology research and development services. The Hilotherm product family consists of three core temperature-controlled cooling devices (Professional, HomeCare, and ChemoCare) supported by anatomical cuffs, accessories, and service kits. The company also provides biotechnology research services including molecular modeling, bio-catalysis, and clinical pipeline development through its Bucharest R&D facility.

Differentiator

Problem solved

Functional benefit

Products and services

• Hilotherm Professional Flagship portable single-cuff hilotherapy device for clinical practice, sports clubs, home or hospital use, providing precision temperature-controlled cold-water therapy for post-surgical recovery. Distributed by Cristiana Bio Tech in Romania.
• Hilotherm HomeCare Compact single-channel hilotherapy unit designed for at-home recovery, delivering continuous temperature-controlled cold-water therapy through anatomically-shaped cuffs. Available in Romania via Cristiana Bio Tech.
• Hilotherm ChemoCare Clinical hilotherapy device providing scalp and extremity cooling to support patients during chemotherapy treatment, reducing side effects. Distributed by Cristiana Bio Tech in Romania.
• Hilotherm Cuffs & Accessories Anatomically-shaped single-use and reusable cuffs covering full-face, eye, trapezius/shoulder, chest, forearm, area (large/small), calf, and foot/slipper areas, compatible with all Hilotherm devices. Sold by Cristiana Bio Tech in Romania.
• Hilotherm Service Kits & Transport Bags Service kits and carrying cases for Hilotherm devices including maintenance supplies (brushes, tank caps, vaseline, wipes) and padded transport bags for device portability. Distributed by Cristiana Bio Tech in Romania.
• Biotechnology R&D Services Research and development services in computational bio, sustainable innovation, and health/life sciences delivered from Cristiana Bio Tech's ISO-certified Bucharest R&D hub for partners and clients.
• Service Plans, Clinical Training & Support Ongoing service plans, clinical staff training, and support services for medical staff using Hilotherm equipment, including spare parts and consumables. Delivered by Cristiana Bio Tech in Romania.

Quantifiable outcome

• 70% reduction in in-vitro testing cycles through molecular modeling
• +2 more outcomes

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability1 record

Feature4 records

Partnerships

Three partnerships are on record, tiered core and minor.

• KLS Martin GroupcoreChannel Partner/ Reseller/ DistributorKLS Martin Group is a medical technology company specializing in craniomaxillofacial (CMF) surgery solutions. Cristiana Bio Tech partners with KLS Martin as an industry collaborator, distributing their products (patient-specific implants, cutting guides) and participating in joint CMF symposiums and educational events in Romania. The partnership serves Romanian maxillofacial surgery specialists.
• HilothermcoreChannel Partner/ Reseller/ DistributorHilotherm is a manufacturer of precision temperature-controlled hilotherapy (continuous cold-water therapy) medical devices. Cristiana Bio Tech serves as the Romanian distributor for the full Hilotherm product line including Professional, HomeCare, and ChemoCare devices along with anatomical cuffs and accessories. This is a core distribution partnership for post-surgical recovery products.
• Alpha BiominorChannel Partner/ Reseller/ DistributorAlpha Bio is a dental implant company. Cristiana Bio Tech was founded building on the Alpha Bio dental implant heritage (2006), indicating historical partnership or distribution relationship for dental biotechnology products. The company has since expanded beyond dental implants.

Scale indicators4 records

Recent moves7 records

Expansion highlights4 records

Direct peers

• Hilotherm GmbH: Manufacturer of the Hilotherm hilotherapy device line that Cristiana Bio Tech distributes exclusively in Romania. Direct counterparty and potential channel bypass risk — Hilotherm could enter Romania directly or shift distributors, making it the single most comparable company for benchmarking the device distribution business.
• KLS Martin Group: German medical technology company specializing in craniomaxillofacial surgery solutions. KLS Martin is one of CDB's core strategic partners and its products are co-distributed through the same Romanian clinical network; comparison is direct on go-to-market approach for surgical specialist channels.

Broad incumbents

• Eurofins Scientific: Global contract laboratory testing and R&D services group with deep European footprint. Comparable as a broad incumbent offering scientific R&D services similar in nature to CDB's biotech R&D arm, but at vastly greater scale.
• Charles River Laboratories: Major preclinical CRO providing discovery, pharmacology, and DMPK services — directly overlapping the category coded to CDB's biotech research activity. Useful benchmark for unit economics and capabilities expected of a credible preclinical research services provider.
• Bio-Techne: Manufacturer of reagents, proteins, and assay kits used in biotechnology research. Comparable for the LNP matrices, enzymatic agents, and bio-catalysis reagents that CDB describes as part of its research portfolio — illustrates the scale and breadth a specialist reagent supplier typically needs.
• QIAGEN: Provider of molecular biology reagents, sample technologies, and bioinformatics — adjacent to CDB's molecular modeling and LNP delivery research. Useful benchmark for the commercial trajectory of a mid-cap life science tools company serving discovery-stage research customers.
• Sartorius AG: Bioprocessing and laboratory equipment supplier. Relevant comparator for the lab infrastructure side of CDB's Bucharest R&D hub (cleanrooms, chromatography, spectrophotometry) and for valuation framing of capital-intensive life science tools businesses.
• IQVIA: Largest global clinical CRO with significant European operations. Comparable as a broad incumbent in the contract research space, providing perspective on the scale gap between a five-person Bucharest team and the leading CROs in the same value chain.

Regional players

• MedLife: Largest private healthcare provider in Romania, with hospital, clinic, and laboratory operations nationwide. Regional comparison for the local healthcare ecosystem that CDB serves and a benchmark for the addressable Romanian clinical market.
• Synevo Romania: Medical laboratory network operating across Romania and CEE as part of the Medicover group. Regional comparison point for laboratory and clinical testing services in Romania, illustrating the scale of established lab-services operators in CDB's home market.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/cristianabiotech

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about cristiana bio tech