Developer docs
API playgroundTry for free, no card

Search company profiles

.406 Ventures

Full company profile

uuid000027c

Namestring
.406 Ventures
Legal namestring
406 Ventures Management, L.P.
Websiteurl
406ventures.com
Company typeenum
Private
Founded yearint
2005
Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
11–50
akta.pro rankint
HeadquartersBoston, United States
HQ citystring
Boston
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
venture capital investing, early-stage funding, seed stage capital, series A investing, healthcare venture capital
Industry2 codes
1Early-Stage Venture Capital (Series A/B)
CodeFSANAAABPrimaryYes
2Sector-Focused Venture Capital (Vertical Specialists)
CodeFSANAAADPrimaryNo
NAICS code1 code
  • Portfolio Management and Investment Advice52394
SIC code1 code
  • Investment Advice6282
Product category
Venture Capital
GTM motion1 record

Each record includes

Type, Description, Source

Revenue model2 records
1Management Fees
TypeSubscription Recurring
Description

Venture capital firms typically charge management fees (typically 2% of assets under management) to cover operational expenses. .406 Ventures manages $1.3B+ in capital.

406ventures.com
2Carried Interest
TypeLicensing Royalties
Description

Performance-based carried interest from successful portfolio company exits. Notable exits include AbleTo (acquired by Optum for $470M), Corvus (acquired by Travelers), Iora Health (acquired by One Medical/Amazon), and Health Dialog (acquired by Bupa). These exits demonstrate successful realization of carried interest.

406ventures.com
Marketing channels6 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components4 values
Personnel, Operations, Marketing or Sales, Others
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

.406 Ventures is a venture capital firm that provides seed and Series A equity capital to early-stage technology companies, primarily in healthcare, data + AI, and cybersecurity sectors. Beyond capital, the firm supplies founders with strategic guidance, talent and customer introductions through its Executive Councils, and operational support via its Executives in Residence and Student Fellows programs. The firm manages over $1.3B in capital across 94 portfolio companies.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

.406 Ventures is an early-stage venture capital firm that operates as a single investment fund/product. The firm provides venture capital investment services alongside complementary programs including the Student Fellows Program for aspiring entrepreneurs, the Executives in Residence (EIR) Program for senior executives, and Executive Councils spanning Healthcare, Data + AI, and Cybersecurity sectors. The firm's primary offering is its VC fund managing $1.3B+ capital across 94 portfolio companies focused on healthcare, data + AI, and cybersecurity.

Product and service1 record
1.406 Ventures VC Fund
CategoryCore product
Description

Venture capital fund investing seed and Series A equity capital into early-stage technology companies in healthcare, data + AI, and cybersecurity. The firm manages over $1.3B in capital across 94 portfolio companies and provides practical resources beyond capital including strategic guidance, network access, and operational support.

Scale indicator8 records

Each record includes

Type, Value, Description, Source

Partnership3 partners
1Healthcare Executive Council Members
Strategic tierCoreTypeStrategic or Co-development Partner
Description

50+ executives from leading healthcare organizations including Amazon Web Services, Ascension, BCBS North Carolina, Boston Children's Hospital, Cigna Evernorth, Cleveland Clinic, and others who provide insights and connections for portfolio companies.

2Data + AI Executive Council Members
Strategic tierCoreTypeStrategic or Co-development Partner
Description

75+ executives from data and AI-focused companies including American Express, AWS, Blue Health Intelligence, Fidelity, IBM, JP Morgan, Netflix, Salesforce, and others who provide market intelligence and potential customer connections.

3Cybersecurity Executive Council Members
Strategic tierCoreTypeStrategic or Co-development Partner
Description

100+ cybersecurity leaders from organizations including JPMC, Wells Fargo, Target, GE, Johnson & Johnson, Oracle, and others who provide expertise and potential customer access for cybersecurity portfolio companies.

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
1Flare Capital Partners
TypeDirect peer
Description

Boston-based early-stage venture firm exclusively focused on healthcare technology and services. Closest direct peer because of overlapping healthcare thesis, similar early-stage check sizes, and shared Boston/Northeast ecosystem that competes for the same founders.

2Define Ventures
TypeDirect peer
Description

Early-stage venture firm dedicated to digital health companies, co-led by Lynne Chou O'Keefe and backed by strategic LPs. Directly comparable in healthcare-only thesis, seed/Series A focus, and portfolio-level category-defining bar.

3LRVHealth
TypeDirect peer
Description

Boston-headquartered early-stage venture firm investing exclusively in healthcare. Co-investor with .406 in Diana Health and operates in the same New England healthcare innovation corridor, creating direct overlap on deals.

4Norwest Venture Partners
TypeBroad incumbent
Description

Large multi-stage venture firm with a dedicated healthcare practice. Lead investor in Diana Health alongside .406; broadly comparable on healthcare investing but competes from a much larger AUM base and writes later/follow-on checks .406 cannot.

5Cyberstarts
TypeDirect peer
Description

Early-stage venture firm exclusively focused on cybersecurity with concentrated thesis in offensive and defensive security software. Direct peer in the cybersecurity vertical of .406's three-pillar model.

6Bessemer Venture Partners
TypeBroad incumbent
Description

Multi-stage venture firm with deep healthcare, data, and cybersecurity exposure and similar long-dated early-stage posture. Broader incumbent that overlaps on theses and exits but competes from significantly larger AUM and global footprint.

7M12 (Microsoft's Venture Fund)
TypeEmerging player
Description

Corporate venture fund backed by Microsoft investing in enterprise software, AI infrastructure, and cybersecurity. Comparable through its AI/data and cybersecurity focus, but offers portfolio companies hyperscaler distribution that .406 cannot match on its own.

8Andreessen Horowitz (a16z)
TypeBroad incumbent
Description

Multi-stage venture firm with dedicated bio/health, infrastructure, and security funds that mirror .406's three pillars. Much larger AUM and broader platform; competes for the same category-defining breakout rounds but typically at growth-stage check sizes.

9Bain Capital Ventures
TypeBroad incumbent
Description

Multi-stage venture arm of Bain Capital with fintech, application software, and infra practices. Overlaps with .406 on the data/AI and enterprise security theses at larger check sizes and from a broader LP base.

10New Markets Venture Partners
TypeDirect peer
Description

Early-stage venture firm focused on healthcare innovation in underserved markets. Co-investor with .406 in FamilyWell Health's Series A; comparable on healthcare-only vertical and similar seed/Series A posture.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers13 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment4 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile3 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
No
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles15 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment220 records

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

.406 Ventures

Venture Capital406ventures.com

.406 Ventures firmographics

Firmographics
Name
.406 Ventures
Legal name
406 Ventures Management, L.P.
Website
https://406ventures.com
Company type
Private
Founded year
2005
Operating status
Operating
Headcount range
11–50 employees
Ownership category
akta.pro rank

.406 Ventures industry classification

Industry
Product category
Venture Capital
NAICS
Portfolio Management and Investment Advice (52394)
SIC
Investment Advice (6282)
akta.pro primary industry
Early-Stage Venture Capital (Series A/B) (FSANAAAB)
akta.pro secondary industry
Sector-Focused Venture Capital (Vertical Specialists) (FSANAAAD)

Keywords

  • Venture capital investing
  • Early-stage funding
  • Seed stage capital
  • Series A investing
  • Healthcare venture capital

Where .406 Ventures is headquartered

Location

Headquarters

HQ city
Boston
HQ country
United States
HQ region
North America

Offices1 record

Markets served

.406 Ventures business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Operations, Marketing or Sales, Others

Revenue model

  1. Management Fees: Venture capital firms typically charge management fees (typically 2% of assets under management) to cover operational expenses. .406 Ventures manages $1.3B+ in capital.
  2. Carried Interest: Performance-based carried interest from successful portfolio company exits. Notable exits include AbleTo (acquired by Optum for $470M), Corvus (acquired by Travelers), Iora Health (acquired by One Medical/Amazon), and Health Dialog (acquired by Bupa). These exits demonstrate successful realization of carried interest.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels6 records

.406 Ventures product offering

Product offering

Core offering

.406 Ventures is a venture capital firm that provides seed and Series A equity capital to early-stage technology companies, primarily in healthcare, data + AI, and cybersecurity sectors. Beyond capital, the firm supplies founders with strategic guidance, talent and customer introductions through its Executive Councils, and operational support via its Executives in Residence and Student Fellows programs. The firm manages over $1.3B in capital across 94 portfolio companies.

Product overview

.406 Ventures is an early-stage venture capital firm that operates as a single investment fund/product. The firm provides venture capital investment services alongside complementary programs including the Student Fellows Program for aspiring entrepreneurs, the Executives in Residence (EIR) Program for senior executives, and Executive Councils spanning Healthcare, Data + AI, and Cybersecurity sectors. The firm's primary offering is its VC fund managing $1.3B+ capital across 94 portfolio companies focused on healthcare, data + AI, and cybersecurity.

Differentiator

Problem solved

Functional benefit

Products and services

  • .406 Ventures VC Fund Venture capital fund investing seed and Series A equity capital into early-stage technology companies in healthcare, data + AI, and cybersecurity. The firm manages over $1.3B in capital across 94 portfolio companies and provides practical resources beyond capital including strategic guidance, network access, and operational support.

Companies that use .406 Ventures

Customer profile

Named customers13 records

Segments4 records

Ideal customer profiles3 records

.406 Ventures technology and API

Technology

Technology focussed No

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

.406 Ventures partnerships and signals

Strategic signal

Partnerships

Three partnerships are on record, tiered core.

  • Healthcare Executive Council MemberscoreStrategic or Co-development Partner50+ executives from leading healthcare organizations including Amazon Web Services, Ascension, BCBS North Carolina, Boston Children's Hospital, Cigna Evernorth, Cleveland Clinic, and others who provide insights and connections for portfolio companies.
  • Data + AI Executive Council MemberscoreStrategic or Co-development Partner75+ executives from data and AI-focused companies including American Express, AWS, Blue Health Intelligence, Fidelity, IBM, JP Morgan, Netflix, Salesforce, and others who provide market intelligence and potential customer connections.
  • Cybersecurity Executive Council MemberscoreStrategic or Co-development Partner100+ cybersecurity leaders from organizations including JPMC, Wells Fargo, Target, GE, Johnson & Johnson, Oracle, and others who provide expertise and potential customer access for cybersecurity portfolio companies.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

.406 Ventures competitors and assessment

Company assessment

Direct peers

  • Flare Capital Partners: Boston-based early-stage venture firm exclusively focused on healthcare technology and services. Closest direct peer because of overlapping healthcare thesis, similar early-stage check sizes, and shared Boston/Northeast ecosystem that competes for the same founders.
  • Define Ventures: Early-stage venture firm dedicated to digital health companies, co-led by Lynne Chou O'Keefe and backed by strategic LPs. Directly comparable in healthcare-only thesis, seed/Series A focus, and portfolio-level category-defining bar.
  • LRVHealth: Boston-headquartered early-stage venture firm investing exclusively in healthcare. Co-investor with .406 in Diana Health and operates in the same New England healthcare innovation corridor, creating direct overlap on deals.
  • Cyberstarts: Early-stage venture firm exclusively focused on cybersecurity with concentrated thesis in offensive and defensive security software. Direct peer in the cybersecurity vertical of .406's three-pillar model.
  • New Markets Venture Partners: Early-stage venture firm focused on healthcare innovation in underserved markets. Co-investor with .406 in FamilyWell Health's Series A; comparable on healthcare-only vertical and similar seed/Series A posture.

Broad incumbents

  • Norwest Venture Partners: Large multi-stage venture firm with a dedicated healthcare practice. Lead investor in Diana Health alongside .406; broadly comparable on healthcare investing but competes from a much larger AUM base and writes later/follow-on checks .406 cannot.
  • Bessemer Venture Partners: Multi-stage venture firm with deep healthcare, data, and cybersecurity exposure and similar long-dated early-stage posture. Broader incumbent that overlaps on theses and exits but competes from significantly larger AUM and global footprint.
  • Andreessen Horowitz (a16z): Multi-stage venture firm with dedicated bio/health, infrastructure, and security funds that mirror .406's three pillars. Much larger AUM and broader platform; competes for the same category-defining breakout rounds but typically at growth-stage check sizes.
  • Bain Capital Ventures: Multi-stage venture arm of Bain Capital with fintech, application software, and infra practices. Overlaps with .406 on the data/AI and enterprise security theses at larger check sizes and from a broader LP base.

Emerging players

  • M12 (Microsoft's Venture Fund): Corporate venture fund backed by Microsoft investing in enterprise software, AI infrastructure, and cybersecurity. Comparable through its AI/data and cybersecurity focus, but offers portfolio companies hyperscaler distribution that .406 cannot match on its own.

Market position

Strengths5 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

.406 Ventures social profiles

Digital presence

.406 Ventures financial estimates

Financial estimate

Revenue estimate

Valuation estimate

.406 Ventures leadership team

Management profile

Number of profiles

Profiles15 records

.406 Ventures funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

.406 Ventures M&A and investment

M&A and investment

M&A

Investments220 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about .406 Ventures

What does .406 Ventures do?

.406 Ventures is a venture capital firm that provides seed and Series A equity capital to early-stage technology companies, primarily in healthcare, data + AI, and cybersecurity sectors. Beyond capital, the firm supplies founders with strategic guidance, talent and customer introductions through its Executive Councils, and operational support via its Executives in Residence and Student Fellows programs. The firm manages over $1.3B in capital across 94 portfolio companies.

Is .406 Ventures a public or private company?

.406 Ventures is a private company. It is classified as founder individual operated bootstrapped and is currently operating.

When was .406 Ventures founded?

.406 Ventures was founded in 2005. It employs 11 to 50 people.

Where is .406 Ventures based?

.406 Ventures is headquartered in Boston, United States, in the North America region.

How does .406 Ventures make money?

Two revenue lines are on record. Management Fees are the primary driver. The others are carried Interest.

Who are .406 Ventures's main competitors?

Direct peers on record are Flare Capital Partners, Define Ventures, LRVHealth, Cyberstarts and New Markets Venture Partners. Broad incumbents are Norwest Venture Partners, Bessemer Venture Partners, Andreessen Horowitz (a16z) and Bain Capital Ventures. M12 (Microsoft's Venture Fund) is listed as an emerging player.

Does .406 Ventures have an API?

No public API is recorded for .406 Ventures.

What industry is .406 Ventures in?

.406 Ventures's product category is Venture Capital. Its primary akta.pro industry code is FSANAAAB, Early-Stage Venture Capital (Series A/B), with a secondary code of FSANAAAD, Sector-Focused Venture Capital (Vertical Specialists). Its NAICS code is 52394 and its SIC code is 6282.

Unlock the full company data

50 free credits on sign-up, no credit card required.

Contact sales
Live signals
BioSpaceTeal Health Raises $22 Million Series A to Expand Access to the Most Accurate FDA-Authorized At-Home HPV Cervical Cancer ScreeningTeal Health raised $22 million in Series A funding led by .406 Ventures to expand access to its FDA-authorized at-home HPV cervical cancer screening device. The round brings total funding to $45 million and supports partnerships ahead of broad insurance coverage in January 2027.Pulse 2.0.406 Ventures Marks 20 Years With 100th Investment In Teal Health And Promotion Of Kathryn Taylor Reddy.406 Ventures is celebrating its 20th anniversary with its 100th portfolio investment in Teal Health and the promotion of Kathryn Taylor Reddy to Partner. The firm has raised over $1.3 billion across five core funds and three opportunity funds, with six portfolio companies achieving unicorn status. It will host a private celebration at Boston's Institute of Contemporary Art.Morningstar.406 Ventures Marks 20 Years With 100th Investment and Promotion of Kathryn Taylor ReddyOn September 22, 2026, .406 Ventures celebrated its 20th anniversary with its 100th portfolio investment in Teal Health and the promotion of Kathryn Taylor Reddy to Partner. The firm has raised over $1.3 billion across five core funds and made 100 investments, six of which have reached unicorn status.VenturecapitalTeal Health Raises $22 Million in Series A Funding Led by .406 VenturesTeal Health raised $22 million in Series A funding led by .406 Ventures to expand access to at-home HPV screening. The round brings total funding to $45 million, with new participation from MPower Partners. The company plans to expand payor partnerships and direct-purchase options, aiming to make screening routine nationwide.Tracxn2026 Funding Rounds & List of InvestorsHYPR has raised multiple funding rounds from 2014 to 2024, with the most recent being a Series D in June 2024. The rounds include Series A through Series D, with lead investors such as RRE Ventures, Mastercard, and .406 Ventures.StartupmagCybersecurity firm Mindgard raises £22.2m led by Album VC and Karma VenturesMindgard, a cybersecurity startup spun out of Lancaster University, raised £22.2m in a Series A round led by Album VC with participation from Karma Ventures. The funding will scale its AI security platform, which has identified over 150 vulnerabilities in AI applications. The company plans to expand globally as enterprises adopt AI.Venture Capital Access OnlineMindgard Raises $30M Series A by Turning Attacker Behavioral Intelligence into Effective AI DefenseMindgard closed a $30 million Series A led by Album VC, using funds to scale product, engineering, sales, and marketing. Its platform has disclosed over 150 high-impact vulnerabilities in AI products, including a zero-day in Cursor IDE and guardrail failures in ChatGPT.FinSMEsMindgard Raises $30M in Series A FundingMindgard, an AI security platform provider, raised $30M in Series A funding led by Album VC. The company will use the funds to scale product, engineering, sales, and marketing. Its platform offers shadow AI discovery, red teaming, and run-time protection for AI systems.Pulse 2.0RELAI Raises $6.9 Million And Launches Verifiable Continual Learning Platform For AI AgentsRELAI announced the launch of a verifiable continual learning platform for AI agents that continuously improves from real-world failures while preventing regressions, alongside securing $6.9 million in total funding including a $5.4 million pre-seed round led by .406 Ventures with participation from AITFund, Non sibi Ventures, and TEDCO. The Bethesda, Maryland-based company reported early customer deployments showing validation score improvements from 39% to 80% for a financial services agent and from 62% to 96% for a healthcare proof-of-concept. RELAI, founded by University of Maryland associate professor Soheil Feizi, plans a broader public release on June 22 and will use the capital to expand its engineering team and accelerate go-to-market initiatives.FinSMEsRelai Raises $5.4M in Pre-Seed FundingRelai, a Bethesda-based AI agent continual learning infrastructure company, raised $5.4M in pre-seed funding led by .406 Ventures. The round brings total funding to $6.9M, and the company will use the funds to expand its engineering team and develop the platform.