Positrigo

What Positrigo does

Positrigo AG is a Swiss medical device company founded in 2018 as a spin-off of ETH Zurich, headquartered at Technopark Zurich with a US subsidiary opened in October 2023. The company designs, manufactures, and sells the NeuroLF, an ultra-compact dedicated brain Positron Emission Tomography (PET) scanner that uses silicon photomultiplier (SiPM) detectors and proprietary reconstruction algorithms to enable functional brain imaging at a fraction of the cost, size, and infrastructure requirements of conventional whole-body PET systems. The NeuroLF received FDA 510(k) clearance in July 2024 and CE Mark in October 2024, and is sold primarily to neurology practices, memory and dementia centers, outpatient imaging clinics, and academic medical centers for applications including Alzheimer's disease and other dementias, neuro-oncology, epilepsy, and movement disorders.

Positrigo's revenue model combines capital equipment sales of the NeuroLF system with recurring revenue from service and maintenance contracts (Complete and Preventive Service Programs) and clinical training and application support services. Go-to-market is executed through direct enterprise field sales in the US and key European markets (including a US subsidiary and named reference accounts such as The Neuron Clinic, Beverly Hills Medical Imaging, LMU Hospital Munich, and University Hospital of Genoa), complemented by regional distribution partners APR Salud in Spain and Qualimedis in France. The company invests in clinical education via the Brain PET Talks webinar series, presence at major medical conferences (SNMMI, AAIC, EANM, CTAD, RSNA), whitepapers, and KOL engagement.

The company is venture-backed with approximately CHF 14M+ in disclosed equity and grant funding across rounds led by 4FO Venture Partners, 4FOX Ventures, Zurcher Kantonalbank, ETH Zurich Foundation, HealthCap, and Navivo Capital, supplemented by European Innovation Council and Innosuisse non-dilutive funding. The board includes former Siemens Healthcare CEO Urs Suter as Chairman and senior healthcare operators from GE Healthcare, Siemens, and Roche-affiliated entities, reflecting a deliberate build toward scaled commercialization rather than a research-stage posture.

Name

Positrigo

Legal name

Positrigo AG

Website

https://positrigo.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

11–50 employees

Short description

Positrigo AG develops and sells the NeuroLF, an FDA-cleared and CE-marked ultra-compact dedicated brain PET scanner for neurology practices, imaging centers, and hospitals diagnosing Alzheimer's and other brain disorders.

Ownership category

akta.pro rank

Product category

Nuclear Medicine Imaging Equipment

NAICS

Medical and Diagnostic Laboratories (62151)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Point-of-Care (POC) & Rapid Diagnostics (near-patient, lateral flow) (HLAAALAG)

akta.pro secondary industries

Point-of-Care Testing (POCT) & Near-Patient Labs (HLAFAMAI), Remote Diagnostics & Point-of-Care (Connected Testing, Home Lab Devices) (HLACAPAK)

Keywords

• Dedicated brain PET
• Medical imaging devices
• Functional brain imaging
• PET scanners
• Dementia diagnostic imaging

Headquarters

HQ city

Zürich

HQ country

Switzerland

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. NeuroLF System Hardware Sales: Sale of the NeuroLF dedicated brain PET scanner to healthcare providers including neurology practices, imaging centers, and hospitals. The system is sold as a capital equipment purchase with one-time revenue per unit sold.
2. Service and Maintenance Contracts: Annual service programs including preventive maintenance and technical support. Two service tiers offered: Complete Service Program (covers all technical service costs including annual maintenance inspection) and Preventive Service Program. First year includes factory warranty and free preventive maintenance visit.
3. Clinical Training and Support Services: On-demand clinical training for new staff, continuing education opportunities for trained clinicians, and ongoing clinical application support to ensure efficient system utilization from day one.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

Positrigo develops, manufactures, and sells the NeuroLF, an ultra-compact dedicated brain Positron Emission Tomography (PET) scanner designed for functional brain imaging at the point of care. The system is FDA cleared and CE marked for clinical brain imaging, particularly dementia diagnosis including Alzheimer's disease, with applications in neuro-oncology, epilepsy, movement disorders, and research. Positrigo also provides clinical training/education services and recurring technical maintenance programs as supporting offerings.

Product overview

Positrigo offers a focused portfolio centered on the NeuroLF system, an ultra-compact dedicated brain PET scanner that enables functional brain imaging at a fraction of the cost and space requirements of whole-body PET systems. The product suite includes the NeuroLF hardware system as the core offering, supported by clinical services (training, education, and ongoing support) and technical maintenance services. The NeuroLF system is FDA-cleared and CE-marked, targeting markets in the US and Europe for applications including dementia diagnosis (Alzheimer's disease), neuro-oncology, epilepsy, movement disorders, and clinical research.

Differentiator

Problem solved

Functional benefit

Brands

• NeuroLF: Ultra-compact dedicated brain Positron Emission Tomography (PET) system designed for functional brain imaging, applicable in dementia diagnosis (including Alzheimer's), neuro-oncology, epilepsy, movement disorders, and research.

Products and services

• NeuroLF Brain PET System Ultra-compact dedicated brain Positron Emission Tomography (PET) scanner for point-of-care functional brain imaging. FDA cleared and CE marked. Indicated for clinical brain imaging including dementia diagnosis (Alzheimer's disease, Lewy body, vascular, frontotemporal dementias), neuro-oncology, epilepsy, movement disorders, and research applications. Designed for installation in neurology practices and outpatient imaging centers with limited space requirements, intuitive usability, and a seated patient position.
• Clinical Services Clinical training and ongoing application support for NeuroLF customers, including initial product training, on-demand training for new staff, continuing education opportunities for trained clinicians, webinars (Brain PET Talks), case studies, and clinical whitepapers to ensure efficient system utilization from day one. Targeted at clinical users and nuclear medicine teams at NeuroLF customer sites.
• Technical Maintenance Services Annual technical service programs for installed NeuroLF systems. Includes a Complete Service Program (covers all technical service costs including annual maintenance inspection) and a Preventive Service Program. First year of ownership includes a factory warranty and a free preventive maintenance visit. Provided to NeuroLF customer sites to maintain uptime and performance.

Quantifiable outcome

• 9 out of 10 patients prefer sitting position during scanning vs lying down required by conventional PET systems
• +3 more outcomes

Named customers5 records

Segments6 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators8 records

Recent moves8 records

Expansion highlights7 records

Broad incumbents

• Siemens Healthineers: Global leader in medical imaging including whole-body PET/CT and PET/MR. Sells the broadest installed base of clinical PET scanners worldwide and previously developed the ECAT HRRT dedicated brain PET. Competes with Positrigo for brain imaging volume, but lacks Positrigo's point-of-care compact form factor and outpatient workflow fit. Positrigo's chairman Urs Suter is a former Siemens Healthcare CEO.
• GE HealthCare: Major PET/CT and PET/MR manufacturer with broad hospital and imaging-center footprint. Two of Positrigo's commercial leaders (Global CCO Jerome Descheirder and VP US Sales Brian Oswald) previously held senior roles at GE HealthCare, indicating the talent and customer relationships overlap. Competes with Positrigo on oncology-dominated whole-body PET scanners that also serve brain imaging.
• Philips: Global medical imaging incumbent selling PET/CT and PET/MR systems alongside a broad diagnostic imaging portfolio. Competes for hospital and imaging center capital equipment budgets that could otherwise be deployed for Positrigo's NeuroLF, though Philips does not offer a dedicated brain-only PET system.
• Canon Medical Systems: Sells PET/CT systems as part of a broad diagnostic imaging portfolio (formerly Toshiba Medical). Competes with Positrigo for clinical brain imaging referrals through hospital-based whole-body PET installations, though Canon does not currently offer a dedicated point-of-care brain PET.

Direct peers

• United Imaging Healthcare: Chinese-headquartered medical imaging company rapidly expanding in PET/CT and PET/MR, including dedicated head/neuro PET configurations (e.g., uMI-Panvivo and brain-focused systems). Most direct head-to-head competitor in dedicated brain PET positioning globally, with broader product portfolio and aggressive pricing.

Emerging players

• Cubresa: Canadian-based developer of compact preclinical PET scanners for research and translational imaging. Comparable to Positrigo in miniaturization and SiPM detector focus, though Cubresa targets research institutions and preclinical applications rather than clinical brain imaging. Represents a relevant technical peer in compact PET engineering.
• RefleXion Medical: US-based company developing PET-guided radiation therapy systems for oncology. Shares the PET imaging engineering heritage and ETH Zurich spin-off DNA with Positrigo, though its application (radiotherapy guidance) is materially different. Reflects the broader innovation wave in dedicated and PET-integrated medical imaging devices.

Others

• Bruker: Major scientific instruments company with a significant preclinical PET and PET/MR business (legacy Bruker Biospin / PET technology). Sells compact PET systems primarily to research institutions and pharmaceutical R&D, overlapping with Positrigo's research customer segment but not directly competing in clinical brain imaging.
• Mediso Medical Imaging Systems: Hungarian medical imaging company selling preclinical and clinical PET, SPECT, and hybrid systems. Offers compact and dedicated organ-focused imaging systems that share Positrigo's philosophy of purpose-built imaging. Primarily preclinical/clinical research focus, with some specialty clinical applications overlapping with NeuroLF's research use cases.
• Hermes Medical Solutions: Leading vendor of PET and SPECT image processing, quantification, and visualization software widely used in nuclear medicine and neurology. Complementary rather than competitive with Positrigo, as Hermes software is often deployed alongside PET scanners including NeuroLF for clinical interpretation and quantification (Centiloid scaling, amyloid/tau analysis).

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/playlist?list=PLQP-FmNJLFTZUcSe-rQnD7rVh-qyJqw_f
• LinkedInlinkedin.com/company/positrigo

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Subsidiaries1 record

Funding overview

Funding rounds10 records

Investors12 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Positrigo