Sino Biological
Sino Biological is a Beijing-based, Shenzhen-listed (301047.SZ) biotechnology company that develops and distributes recombinant proteins, antibodies, ELISA kits, and CRO services for life sciences research and drug discovery customers across more than 90 countries.
- Company typePublic
- Founded2007
- HeadquartersBeijing, China
- Headcount251–500
- GTM typeB2B
- OfferingHardware or Manufacturing
What Sino Biological does
Sino Biological, Inc. is a Beijing-headquartered, Shenzhen Stock Exchange-listed (301047.SZ) biotechnology company founded in 2007 that develops, manufactures, and distributes recombinant proteins, antibodies, ELISA kits, viral antigens, cDNA clones, and cell-free protein synthesis reagents for the global life sciences research market. Its technology platform spans multiple expression systems (E. coli, HEK293, CHO, Baculovirus-Insect) plus proprietary cell-free synthesis (XPressMAX™), endotoxin-free protein production at a Houston Center for Bioprocessing (ProPure™), five antibody discovery platforms (Beacon® single B cell, FACS, phage display, hybridoma, rabbit pAb), and a 1,100+ kinase portfolio acquired through the April 2024 purchase of SignalChem Biotech for $48 million USD. The company also offers GMP-grade cytokines and a growing menu of CRO services spanning high-throughput antibody production, cell-free protein expression, multi-pass transmembrane protein development, and ADC/CAR-T/organoid solution workflows.
The company monetizes through a hybrid catalog-plus-CRO model: one-time catalog purchases of off-the-shelf reagents priced at unit economics with promotional discounting, paired with quote-based CRO services covering expression, purification, antibody development, and kinase assay/screening at scales from micrograms to kilograms. Distribution combines direct e-commerce and field sales in the US (Houston and Paoli), Europe (Eschborn, Germany), Japan (Kawasaki), and South Korea (Seoul) with a distributor network covering 50+ additional countries, serving academic institutions, biotechnology companies, and pharmaceutical organizations in over 90 countries. Compliance posture includes ISO 9001, ISO 13485, GMP, CMA, and CNAS certifications, with FDA DMF filing available for GMP-grade cytokines, enabling progression up the value chain from research-use-only reagents toward clinical and cell-therapy manufacturing customers.
Sino Biological firmographics
Firmographics- Name
- Sino Biological
- Legal name
- Sino Biological, Inc.
- Website
- https://sinobiological.com
- Company type
- Public
- Founded year
- 2007
- Operating status
- Operating
- Headcount range
- 251–500 employees
- Short description
- Sino Biological is a Beijing-based, Shenzhen-listed (301047.SZ) biotechnology company that develops and distributes recombinant proteins, antibodies, ELISA kits, and CRO services for life sciences research and drug discovery customers across more than 90 countries.
- Ownership category
- akta.pro rank
Sino Biological industry classification
Industry- Product category
- Life Science Reagents
- NAICS
- Biological Product (except Diagnostic) Manufacturing (325414), In-Vitro Diagnostic Substance Manufacturing (325413), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Biological Products, (No Disgnostic Substances) (2836), In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)
- akta.pro secondary industries
- Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI), Analytical Development & QC Testing (Release/Stability/Potency) (HLAGAGAF)
Keywords
Where Sino Biological is headquartered
LocationHeadquarters
- HQ city
- Beijing
- HQ country
- China
- HQ region
- Asia
Offices7 records
Markets served
Sino Biological business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Technology or R&D, Operations, Supply Chain, Marketing or Sales, Infrastructure
Revenue model
- Recombinant Protein and Antibody Catalog Sales: Sale of catalog products including recombinant proteins, antibodies, cDNA clones, ELISA kits, and cell culture media. Products sold directly through website and via global distributor network.
- CRO Services: Contract research organization services including recombinant protein expression, antibody production, assay development, and compound screening. Services range from high-throughput screening to large-scale production (μg to kg scale).
- Cell-Free Protein Synthesis Kits: Sale of XPressMAX™ Cell-Free Protein Synthesis Kit and related reagents for high-throughput protein expression.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | Standard catalog products with periodic promotional discounts |
Go-to-market motion3 records
Distribution channels4 records
Marketing channels7 records
Sino Biological product offering
Product offeringCore offering
Sino Biological manufactures and sells recombinant proteins, antibodies, ELISA kits, kinases, and related bioreagents through a catalog of over 77,000 products, and provides CRO services for antibody development, protein expression, and drug discovery. The company also operates proprietary cell-free protein synthesis (XPressMAX), endotoxin-free protein production (ProPure), and a kinase portfolio acquired via SignalChem, serving life sciences researchers in over 90 countries.
Product overview
Sino Biological is a global life science reagent provider and CRO services company offering a comprehensive portfolio of recombinant proteins, antibodies, and custom services. The core offerings include the XPressMAX™ Cell-Free Protein Synthesis Kit for ultra-fast protein production in 3 hours, ProPure™ Endotoxin-Free Proteins achieving <0.05 EU/mg endotoxin levels, and the largest recombinant Tau protein library. The company operates the SignalChem Biotech kinase portfolio (acquired 2024) providing 1,100+ highly active kinases, along with ELISA/ELISpot assay kits, SwiftFluo® TR-FRET kinase assays, GMP-grade cytokines, and site-specifically labeled proteins. CRO services span antibody development (recombinant, humanization, bispecific), protein expression (mammalian, baculovirus, bacterial, cell-free), single B cell screening (Beacon®, FACS), and specialized services for ADC, CAR-T/CAR-NK, and organoid research. The company operates production facilities in Beijing, Houston (Center for Bioprocessing), Vancouver (SignalChem), and European operations in Germany, serving researchers in over 90 countries.
Differentiator
Problem solved
Functional benefit
Brands
- ProPure™: Endotoxin-free recombinant proteins product line achieving endotoxin levels below 0.05 EU/mg, produced at the Center for Bioprocessing in Texas. Used for preclinical studies, animal immunization, cell-based assays, and sensitive biopharmaceutical applications.
- XPressMAX™
- EliteRmab®
- SwiftFluo®
- Center for Bioprocessing (C4B)
- ProVir®
Products and services
- XPressMAX Cell-Free Protein Synthesis Kit Ultra-fast cell-free protein synthesis kit enabling protein and antibody expression in approximately 3 hours with greater than 99% success rate. Uses optimized E. coli lysates and supports plasmid and linear DNA templates, disulfide bonding, and high-throughput screening for VHH, scFv, Fab, and miniproteins, targeting researchers using AI-driven antibody design.
- ProPure Endotoxin-Free Proteins Endotoxin-free recombinant proteins produced at the Center for Bioprocessing in Texas, achieving endotoxin levels below 0.05 EU/mg (10x below the USP <85> standard of 0.5 EU/mg). Covers ADC targets, cell therapy-related proteins, immune checkpoints, cytokines, and viral antigens for preclinical studies, animal immunization, and cell-based assays.
- Tau Proteins World's largest recombinant Tau protein library featuring diverse isoforms (0N3R, 1N3R, 2N3R, 0N4R, 1N4R, 2N4R), kinase-phosphorylated Tau proteins, Tau mutants (including P301L, P301S), and biotinylated Tau proteins for neurodegenerative disease research.
- Recombinant Proteins Comprehensive catalog of recombinant proteins including cytokines, growth factors, immune checkpoint proteins, enzymes, Fc receptors, signaling proteins, transmembrane proteins, viral antigens, and therapeutic targets, available in multiple expression systems (E. coli, HEK293, CHO, Baculovirus-Insect).
- Antibodies Broad portfolio of antibodies including EliteRmab rabbit monoclonal antibodies, phospho-specific antibodies, primary antibodies, neutralizing antibodies, virus antibodies, control antibodies, and research-grade biosimilar antibodies for various research applications.
- SignalChem Biotech Kinase Portfolio Following the 2024 acquisition, SignalChem Biotech offers 1,100+ highly active kinases covering more than 90% of the human kinome, 400+ clinically relevant mutant kinases, custom enzyme and assay development, and compound screening/profiling services cited in 2,000+ customer publications.
- ELISA Kits and ELISpot Assay Kits High-quality ELISA kits for cytokine quantification (IFN-gamma, TNF-alpha, IL-2, IL-4, IL-6) and ELISpot detection kits with sensitivity for single-cell detection and ready-to-use pre-coated plates for vaccine development and drug screening.
- SwiftFluo TR-FRET Kinase Assay Kits Ready-to-use time-resolved fluorescence resonance energy transfer (TR-FRET) kits for high-throughput screening of kinase inhibitors, profiling over 60 tyrosine kinases, 150 serine/threonine kinases, and 15 cyclin-dependent kinases.
- GMP-grade Cytokines Good Manufacturing Practice grade cytokines including EGF, Activin A, and others with ISO 9001, ISO 13485, and GMP certification, FDA DMF filing available, suitable for cell therapy manufacturing and clinical applications.
- Beacon Single B Cell Screening CRO Service Single B cell discovery CRO service enabling obtainment of positive clones within 35 days with 99.5% monoclonality rate for antibody discovery campaigns.
- Cell-Free Protein Expression CRO Service Contract research service using cell-free expression technology delivering proteins in as fast as 5 days with greater than 99% success rate for high-throughput antibody discovery and protein production.
- High-Throughput Antibody Production CRO Service Recombinant antibody production service from gene to purified antibody in as fast as 10 days, supporting more than 10,000 antibodies per month in formats including IgG, bispecific antibodies, VHH, and scFv.
- ProPure Endotoxin-Free Protein Expression CRO Service Custom endotoxin-free protein expression service at Center for Bioprocessing (C4B) in Texas using mammalian expression systems (HEK293, ExpiCHO) achieving greater than 90% purity and endotoxin levels below 0.05 EU/mg with delivery in as fast as 2 weeks.
- Multi-pass Transmembrane Protein Development CRO Service Specialized service for expression and purification of challenging multi-pass transmembrane proteins using VLP-based technology platform for drug discovery and structural biology applications.
- ProVir Viral Reagent Bank Comprehensive viral reagent collection covering more than 50 viruses including influenza, SARS-CoV-2 variants, RSV, MPXV, Nipah virus, herpes virus, VZV, RABV, HPV, Hantavirus, and CHIKV for infectious disease research, vaccine development, and diagnostic applications.
- Site-specifically Labeled Proteins Proteins with site-specific labeling (biotin, fluorophores) for precise detection and quantification in assay development, with consistent labeling efficiency and retention of biological activity.
- Influenza Vaccine Strain Antigens 2026-2027 Recombinant antigens for the 2026-2027 Northern Hemisphere influenza vaccine strains following WHO recommendations, covering H1N1 (A/Missouri/11/2025), H3N2 subclade K, and B/Victoria lineage strains to support global flu vaccine development.
- Anti-G4S and Anti-Whitlow/218 Linker Rabbit mAbs (CAR Linker Antibodies) Universal CAR detection antibodies specifically binding to G4S or Whitlow/218 linkers between heavy and light chains of scFv fragments, available in multiple conjugates (FITC, PE, APC, AF488, AF647, Biotin) for flow cytometry applications across CAR-T development workflows.
- EliteScience VIP Partnership Program Premium partnership service program for European researchers offering prioritized production and shipping, risk-free CRO services with a no-results-no-fee policy, and priority access to more than 77,000 in-stock reagent samples, including 24-hour local technical assistance.
Quantifiable outcome
- Protein synthesis in 3 hours with >99% success rate
- +4 more outcomes
Companies that use Sino Biological
Customer profileNamed customers3 records
Segments4 records
Ideal customer profiles3 records
Sino Biological technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability1 record
Feature5 records
Sino Biological partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- SignalChem Biotech Inc.coreSino Biological finalized acquisition of Vancouver-based SignalChem Biotech Inc. for $48 million USD, making it a wholly-owned subsidiary. The acquisition enhances Sino Biological's enzyme production capabilities and broadens its technology platform for life sciences research and drug discovery. SignalChem brings expertise in bioactive enzymes, 1,100+ highly active kinases, and 400+ clinically relevant mutant kinases.
Scale indicators15 records
Recent moves6 records
Expansion highlights6 records
Sino Biological competitors and assessment
Company assessmentDirect peers
- Bio-Techne: Direct competitor in recombinant proteins, antibodies, ELISA kits, and cytokines (R&D Systems brand). Most comparable public peer for Sino Biological's core catalog and CRO services.
- GenScript: Direct competitor headquartered in New Jersey with major operations in China. Offers gene synthesis, recombinant proteins, antibodies, and CRO services — virtually identical product set to Sino Biological.
- ACROBiosystems: Direct competitor in recombinant proteins, especially for biologics, bispecific antibodies, and cell therapy targets. Closest pure-play peer given similar China-rooted operations and biopharma-focused catalog.
- Abcam: Direct peer in research-use antibodies and related reagents (now part of Danaher). Comparable catalog breadth and academic/biopharma customer overlap with Sino Biological's antibody business.
- Cell Signaling Technology: Direct peer in signaling-pathway antibodies, phospho-specific reagents, and kinase-related tools. Overlaps with Sino Biological's kinase portfolio (SignalChem) and signaling protein catalog.
- PeproTech: Specialist in recombinant cytokines and growth factors, now part of Thermo Fisher. Overlaps directly with Sino Biological's cytokine catalog and GMP-grade cytokine positioning.
Broad incumbents
- Thermo Fisher Scientific: Broad life sciences incumbent (Gibco, Invitrogen, Thermo Scientific brands) offering proteins, antibodies, and CRO services as part of a much larger portfolio. Key competitive constraint on Sino Biological's enterprise wins.
- Bio-Rad Laboratories: Broad incumbent in life science research reagents, including antibodies, proteins, and instrumentation. Competes with Sino Biological across multiple product lines but as one of many priorities.
Emerging players
- Miltenyi Biotec: Privately-held peer with strong positions in cell/gene therapy reagents and flow cytometry antibodies. Emerging competitor in adjacent CAR-T and cell therapy reagent markets where Sino Biological is also investing.
- Repligen: Specialist in bioprocessing and biomanufacturing consumables including proteins, enzymes, and chromatography reagents. Comparable in bioprocess reagent focus but with stronger upstream biomanufacturing positioning.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
Sino Biological social profiles
Digital presenceSino Biological compliance and trust
Trust signalCompliance6 records
Sino Biological financial estimates
Financial estimateRevenue estimate
Valuation estimate
Sino Biological leadership team
Management profileNumber of profiles
Profiles4 records
Sino Biological subsidiaries and ownership
Company hierarchySubsidiaries5 records
Sino Biological funding detail
Funding detailFunding overview
Funding rounds2 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Sino Biological M&A and investment
M&A and investmentM&A1 record
Investments3 records
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Sino Biological
What does Sino Biological do?
Sino Biological manufactures and sells recombinant proteins, antibodies, ELISA kits, kinases, and related bioreagents through a catalog of over 77,000 products, and provides CRO services for antibody development, protein expression, and drug discovery. The company also operates proprietary cell-free protein synthesis (XPressMAX), endotoxin-free protein production (ProPure), and a kinase portfolio acquired via SignalChem, serving life sciences researchers in over 90 countries.
Is Sino Biological a public or private company?
Sino Biological is a public company. It is classified as public and is currently operating.
When was Sino Biological founded?
Sino Biological was founded in 2007. It employs 251 to 500 people.
Where is Sino Biological based?
Sino Biological is headquartered in Beijing, China, in the Asia region.
How does Sino Biological make money?
Three revenue lines are on record. Recombinant Protein and Antibody Catalog Sales are the primary driver. The others are CRO Services and cell-Free Protein Synthesis Kits.
Who are Sino Biological's main competitors?
Direct peers on record are Bio-Techne, GenScript, ACROBiosystems, Abcam, Cell Signaling Technology and PeproTech. Broad incumbents are Thermo Fisher Scientific and Bio-Rad Laboratories. Emerging players are Miltenyi Biotec and Repligen.
Does Sino Biological have an API?
No public API is recorded for Sino Biological.
What industry is Sino Biological in?
Sino Biological's product category is Life Science Reagents. Its primary akta.pro industry code is HLAGAIAI, Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes), with a secondary code of HLAAAJAI, Bioprocess Consumables & Reagents (resins, membranes, media components, buffers). Its NAICS code is 325414 and its SIC code is 2836.