What Sanguine does

Sanguine Biosciences Inc. (dba Sanguine Bio) is a private biospecimen procurement platform founded in 2010 and headquartered in San Diego, California, with additional operations in Woburn, Massachusetts (kitting/processing) and Los Angeles, California (apheresis collection). The company operates a direct-to-donor model that recruits and collects human biological samples from a verified community of 70,000+ donors across 100+ disease conditions, bypassing traditional biobank intermediaries. Its catalog spans 979 SKUs across blood-derived products (whole blood, PBMC, plasma, serum, leukopaks, including a GMP-grade line), isolated immune cell populations (CD3+, CD4+, CD8+ T cells, CD19+ B cells, CD56+ NK cells, CD34+ stem cells, cord blood products), and an expanding tissue portfolio (skin punch biopsies, synovial fluid, cerebrospinal fluid).

Sanguine's underlying platform integrates electronic medical records, lab results, and patient-reported outcomes with each sample, and it operates under IRB-approved protocols with 50+ advocacy partnerships (e.g., Lupus LA, ASHA, VF, FSR, IPPF, MPPRN) providing preferential donor access for rare autoimmune and inflammatory diseases. The company monetizes through one-time unit-priced e-commerce sales for in-stock biospecimens (ranging from roughly $132 for healthy serum to $7,140+ for disease-state leukopaks), quote-based prospective custom collections for studies with specific inclusion/exclusion criteria, and bundled lab services (sample processing, cellular analysis, sample testing). GTM is hybrid: a self-serve e-commerce storefront serving mid-market researchers and a consultative enterprise sales motion for custom, longitudinal, and GMP-grade programs.

The company has completed 2,000+ studies with a stated 93% on-spec delivery rate and supports research customers across pharmaceutical/biotech drug discovery, academic medical centers, and CROs. Financing history includes a 2013 seed round, a 2014 Series A of $4M led by Seraph Group, a 2019 NSF grant of $224,981, undisclosed rounds in 2022 and 2023 (BroadOak Capital Partners), and a $10M credit facility from Catalio Capital Management in October 2023. Recent strategic emphasis is on expanding into cell and gene therapy supply (GMP leukopaks, apheresis capacity) and adjacent tissue-based research samples.

Name

Sanguine

Legal name

Sanguine Biosciences Inc.

Website

https://sanguinebio.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

101–250 employees

Short description

Sanguine Biosciences is a direct-to-donor biospecimen procurement platform serving pharmaceutical, biotech, academic, and CRO researchers. It supplies blood-derived, immune cell, and tissue samples with integrated EMR and patient-reported outcome data from a 70,000+ donor community.

Ownership category

akta.pro rank

Product category

Biospecimen Procurement & Research Sample Supply

NAICS

Scientific Research and Development Services (5417)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Trial Sample Collection & Site Phlebotomy Services (HLAGACAJ)

akta.pro secondary industry

Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB)

Keywords

• Human biospecimen procurement
• Biomedical research samples
• Clinical biospecimen supply
• Direct-to-donor biospecimens
• Research sample collection services

Headquarters

HQ city

Woburn

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Biospecimen Product Sales: One-time purchase of human biospecimens including PBMC, serum, plasma, whole blood, leukopaks, and specialized samples like synovial fluid and skin punch biopsies. Products sold in various formats (fresh, frozen, cryopreserved) with prices ranging from approximately $132 for serum to $7,140+ for disease-specific leukopaks.
2. Prospective Custom Collections: Custom collection services where Sanguine recruits donors meeting specific inclusion/exclusion criteria for prospective studies, typically with longer lead times and quote-based pricing.
3. Lab Services: Additional services including sample processing, cellular analysis, and sample testing capabilities that can be bundled with biospecimen purchases.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels4 records

Core offering

Sanguine sells human biospecimens (PBMC, serum, plasma, whole blood, leukopaks, isolated immune cell populations, and tissue fluids such as synovial fluid, cerebrospinal fluid, and skin punch biopsies) directly to biomedical researchers through an e-commerce storefront and custom enterprise quoting. The company pairs every sample with linked Electronic Medical Records and Patient-Reported Outcomes data and offers prospective custom collections, lab processing, cellular analysis, and sample testing as bundled services.

Product overview

Sanguine Biosciences operates a direct-to-donor biospecimen procurement platform providing human biological samples for research. The core product portfolio centers on blood-derived products including Whole Blood, PBMC, Plasma, Serum, Leukopak, GMP Leukopak, and various isolated immune cell populations (CD3+, CD4+, CD8+ T cells, CD19+ B cells, CD56+ NK cells, CD34+ stem cells, and cord blood products). The company expanded into tissue samples with Skin Punch Biopsy, Synovial Fluid, and Cerebrospinal Fluid offerings. Services include Prospective Biospecimen Collection enabling custom inclusion/exclusion criteria and longitudinal studies, OnSite and Community Access collection programs, and Lab Services for processing, cellular analysis, and testing. The platform integrates comprehensive donor data including Electronic Medical Records and Patient-Reported Outcomes. With access to over 70,000 donors across 150+ disease conditions and 50+ advocacy partnerships, the company operates collection facilities in San Diego (HQ), Woburn, MA, and Los Angeles, CA.

Differentiator

Problem solved

Functional benefit

Products and services

• PBMC (Peripheral Blood Mononuclear Cells) Cryopreserved or fresh human peripheral blood mononuclear cells isolated from whole blood, available in cell counts from 5x10^6 to 4x10^9 cells per vial or in bulk format, for immunology, cell therapy, and translational research.
• Whole Blood Human whole blood samples collected from healthy donors and patients with various disease conditions, available in volumes from 20mL to 100mL in fresh or frozen format, for downstream isolation and analysis.
• Plasma Human blood plasma samples collected via standard phlebotomy or apheresis (up to 150mL), available frozen or cryopreserved in 1mL to 60mL volumes, for biomarker, therapeutic, and analytical studies.
• Serum Human blood serum samples processed from whole blood, available frozen, cryopreserved, or fresh in 1mL to 60mL volumes, for diagnostic, biomarker, and disease-state research.
• Leukopak Concentrated white blood cell products collected via apheresis, available in full or half bag sizes in cryopreserved or fresh format, for immunotherapy and cell therapy research applications.
• GMP Leukopak Good Manufacturing Practice (GMP) compliant leukopak products for clinical and commercial cell therapy manufacturing, currently offered for healthy donors.
• CD3+ T Cells Isolated CD3+ T cell populations from peripheral blood for immunotherapy and immunology research.
• CD4+ T Cells Isolated CD4+ helper T cell populations for immunology and vaccine research.
• CD8+ T Cells Isolated CD8+ cytotoxic T cell populations for cancer immunotherapy research.
• CD19+ B Cells Isolated CD19+ B cell populations for antibody therapy and immunology research.
• CD56+ NK Cells Isolated CD56+ natural killer cell populations for cancer immunotherapy and innate immunity research.
• CD34+ Cells Isolated CD34+ hematopoietic stem and progenitor cells for regenerative medicine and cell therapy research.
• Cord Blood Whole cord blood samples containing hematopoietic stem cells for stem cell research and transplantation studies.
• Skin Punch Biopsy Human skin punch biopsy samples in 2mm or 3mm sizes, available fresh or frozen, for dermatology and autoimmune disease research.
• Synovial Fluid Human synovial fluid samples collected from joints, available fresh or frozen in 1mL volumes, for rheumatology and autoimmune research.
• Cerebrospinal Fluid Human cerebrospinal fluid samples for neurological and neurodegenerative disease research.
• Prospective Biospecimen Collection Services Custom biospecimen collection services enabling researchers to specify inclusion/exclusion criteria, conduct longitudinal studies, and access recallable participants with prospective study design.
• Sample Processing Services Laboratory processing services for collected biospecimens including cell isolation and preservation, bundled with biospecimen purchases.
• Cellular Analysis Services Cell analysis laboratory services including characterization and functional testing of cells, offered as a value-add with biospecimen orders.
• Sample Testing Services Testing services for biospecimens including infectious disease screening and quality control prior to delivery to researchers.
• Electronic Medical Records (EMR) Data Access Access to electronic medical and health records data for matched biospecimens to enhance research value and enable clinical correlation studies.
• Patient-Reported Outcomes (PRO) and Surveys Patient-reported outcome data collection via surveys and questionnaires to provide comprehensive research datasets linked to biospecimens.

Quantifiable outcome

• 93% of samples delivered according to study specifications
• +2 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• Lupus LAcoreStrategic or Co-development PartnerPatient advocacy partnership providing access to lupus patient community for biospecimen recruitment and supporting lupus research initiatives.
• American Sjögren's Foundation (ASHA)coreStrategic or Co-development PartnerAdvocacy partnership supporting Sjögren's syndrome research through patient community access and biospecimen recruitment collaboration.
• Vasculitis Foundation (VF)coreStrategic or Co-development PartnerPartnership with Vasculitis Foundation to support research into vasculitis diseases through patient engagement and sample collection programs.
• Foundation for Scleroderma Research (FSR)coreStrategic or Co-development PartnerAdvocacy partnership supporting scleroderma research through community access and biospecimen programs for scleroderma patients.
• International Pemphigus and Pemphigoid Foundation (IPPF)coreStrategic or Co-development PartnerPartnership with IPPF supporting pemphigus and pemphigoid research through patient advocacy network and biospecimen collection collaboration.
• Myositis Patient-Partnered Research Network (MPPRN)coreStrategic or Co-development PartnerPartnership supporting myositis research through patient engagement and collaborative biospecimen programs.
• Various US Clinical PartnersminorStrategic or Co-development PartnerPartnerships across the United States for sample collection and clinical data, enabling synovial fluid and skin punch biopsy offerings for autoimmune, dermatology, rheumatology, and inflammation research.

Scale indicators7 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• iSpecimen: Operates a marketplace platform connecting researchers with biospecimen suppliers and biobanks. Directly comparable to Sanguine's e-commerce/marketplace model for human biospecimens serving pharma, biotech, and academic researchers.
• BioIVT: One of the largest commercial suppliers of human biospecimens and tissue samples to the research and diagnostic industry. Directly comparable to Sanguine's catalog of blood, plasma, serum, and disease-state samples for pharma/biotech research customers.
• Discovery Life Sciences: Global biospecimen provider offering tissue, blood, and cellular products with integrated lab services for research and clinical diagnostics. Comparable as a vertically integrated biospecimen + lab services competitor in oncology, autoimmune, and rare disease samples.
• Cureline: Specialty human biospecimen provider focused on disease-state tissue and biofluids for pharmaceutical and biotech research. Comparable to Sanguine in prospective collection, disease-state biospecimens, and clinical sample procurement for translational research.
• BioChain Institute: Supplier of biospecimens, FFPE tissues, and molecular derivatives for biomedical research. Comparable to Sanguine in catalog biospecimen sales (tissue, blood products) and disease-state sample offerings for research customers.
• ProteoGenex: Provider of human tissue samples and biofluids with clinical data for pharmaceutical research and biomarker discovery. Comparable to Sanguine in custom prospective collections, matched clinical data, and disease-state sample offerings.

Broad incumbents

• Stemcell Technologies: Broader life science tools provider of primary cells, cell culture media, and reagents for research. Overlaps with Sanguine's isolated immune cell products (CD3+, CD4+, CD8+, CD19+, NK cells) and serves similar pharma/biotech researchers, though as part of a wider portfolio.
• Lonza Bioscience Solutions: Global CDMO and bioscience solutions provider offering primary cells, media, and biospecimens through its Bioscience segment. Comparable as a larger incumbent supplying leukopaks, primary cells, and cell therapy starting materials to research and clinical customers.
• Precision Medicine Group: Provider of biospecimen, biomarker, and translational research services to pharma/biotech. Comparable to Sanguine's higher-end prospective collection and lab services (cellular analysis, sample testing) bundled with biospecimens for clinical research customers.

Emerging players

• Boca Biolistics: Specialty biospecimen provider offering disease-state and normal human samples with donor data for research. Comparable to Sanguine in catalog biospecimen sales and prospective collection services, though with a smaller portfolio and more limited apheresis infrastructure.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/sanguinebio
• Facebookfacebook.com/SanguineBio

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds8 records

Investors10 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Sanguine