Bison Ventures

What Bison Ventures does

Bison Ventures is a venture capital firm founded in 2023 by Tom Biegala and Ben Hemani, both previously investors at Cascade Asset Management Company, which manages assets for the Gates Foundation and Gates family members. The firm invests in early-stage frontier technology companies that use innovative science and deep technology to address large-scale global challenges including climate change, untreatable diseases, food security, and AI compute demand. Bison Ventures is structured as Bison Ventures Management Company, LLC, headquartered in San Francisco with a regional office in Seattle, and operates with a six-person team (two founding partners, one partner, two principals, and operations support).

The firm's portfolio spans 17+ companies across seven thematic focus areas: AI in the Physical World (robotics, AI-first scientific tools), Techbio (biological engineering for health and climate), Climate & Sustainability (AI/ML, automation, new materials), Digital + Bio (full-stack hardware), 10x Hardware (step-change hardware innovation), Food & Agriculture, and Connectivity. Disclosed rounds between August 2024 and March 2026 include a $14M seed lead in Great Sky (superconducting optoelectronic AI compute), a $20M Series A co-lead in Grid Aero (autonomous cargo aircraft), a $33.5M Series B lead in Juvena Therapeutics (AI-enabled regenerative biologics), a $20M Series A extension participation in Allonnia (bio-remediation), a $15M Series A lead in Bonsai Robotics (autonomous farming), a $6.8M seed lead in Cadstrom (AI hardware verification), and a $30M participation in InnerPlant (synthetic biology). The firm typically acts as lead or co-lead investor from seed through Series B.

As a venture capital firm, Bison Ventures generates revenue through traditional fund economics — management fees on committed capital and carried interest on fund returns — applied to its approximately $135M founding fund. The firm differentiates from generalist VCs through the deep technical backgrounds of its partners (engineers-turned-investors across materials science, biomedical engineering, and systems engineering) and through the founders' prior track record backing category-defining companies at Cascade Asset Management, including Ginkgo Bioworks (IPO), Schrodinger (IPO), and ChargePoint (SPAC).

Name

Bison Ventures

Legal name

Bison Ventures Management Company, LLC

Website

https://bison.vc

Company type

Private

Founded year

2023

Operating status

Operating

Headcount range

11–50 employees

Short description

Bison Ventures is a San Francisco- and Seattle-based venture capital firm founded in 2023 by former Gates Foundation investors that manages a $135M fund, investing in early-stage frontier technology companies across AI compute, biotech, climate, aerospace, and advanced hardware.

Ownership category

akta.pro rank

Product category

Venture Capital

akta.pro primary industry

Corporate Strategic Partnership & Ecosystem Investment Arms (FSANAHAF)

Keywords

• Venture capital investing
• Deep tech investment
• Early-stage funding
• Frontier technology venture
• Startup equity investment

Headquarters

HQ city

Seattle

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Distribution channels1 record

Marketing channels4 records

Core offering

Bison Ventures is a venture capital firm that deploys patient capital into early-stage frontier technology companies across AI in the physical world (robotics, AI-first scientific tools), techbio, climate and sustainability, digital + bio, 10x hardware, food and agriculture, and connectivity. The firm typically acts as lead or co-investor in seed through Series B rounds and provides strategic and operational support to portfolio founders.

Product overview

Bison Ventures operates as a single unified investment platform, not a product company with multiple modules. As a venture capital firm, it provides funding and strategic support to frontier technology startups. The firm's investment focus spans AI in the Physical World (robotics, AI-first scientific tools), Techbio (biological engineering for health and climate), Climate & Sustainability (AI/ML, automation, new materials), Digital + Bio (full-stack hardware solutions), 10x Hardware (step-change hardware innovations), Food & Agriculture, and Connectivity. The portfolio includes companies across robotics, biotech, AI computing, aerospace, and advanced materials sectors.

Differentiator

Problem solved

Functional benefit

Products and services

• Bison Ventures Investment Services

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Scale indicators2 records

Recent moves4 records

Expansion highlights5 records

Direct peers

• Lux Capital: Long-standing deep-tech and frontier-science venture firm investing across AI, robotics, biotech, climate, and space. Directly comparable to Bison in thesis (science-based, contrarian bets) and stage focus (seed through Series B).
• DCVC (Data Collective): Deep-tech-focused venture firm backing founders using computational, physical, and life-science innovations. Closely aligned with Bison's emphasis on 'deep' technologies that compound from science rather than incremental software.
• Innovation Endeavors: Early-stage deep-tech investor founded by Eric Schmidt, focusing on AI, frontier compute, biotech, and climate. Direct comparable on thesis and stage; Bison has even co-invested alongside Innovation Endeavors (e.g., Cadstrom).
• Material Impact: Venture fund investing in hard-tech and deep-tech startups across materials, robotics, climate, and advanced manufacturing. Directly comparable as a deep-tech-only specialist at similar fund sizes.
• Breakthrough Energy Ventures: Climate-focused deep-tech fund backed by Bill Gates with scientific founders investing patient capital in frontier climate solutions. Highly comparable to Bison's climate-and-sustainability theme and Gates Foundation heritage.
• Susa Ventures: Early-stage venture firm investing in software-centric and frontier-tech companies, with a thesis around category-defining infrastructure and data businesses. Comparable on stage and orientation toward technical founders.

Broad incumbents

• Khosla Ventures: One of the largest and longest-tenured deep-tech VC firms, with broad exposure across AI, biotech, climate, robotics, and frontier science. Operates at much larger AUM but competes head-to-head on the same thesis categories as Bison.
• Andreessen Horowitz (a16z): Mega-VC with dedicated bio/health and deep-tech franchises (a16z Bio, a16z Infra) investing across frontier science and infrastructure. Overlaps with Bison in AI compute, biotech, and frontier verticals but at vastly greater scale and breadth.
• Founders Fund: Peter Thiel-led venture firm known for contrarian, frontier-leaning bets in aerospace, biotech, crypto, and AI. Comparable in contrarian science/tech thesis, though typically operating at Series B and later rather than seed/Series A.

Emerging players

• Eniac Ventures: Seed-stage venture firm backing technical founders across AI, robotics, and frontier software. Comparable on stage and seed-led approach, though with less of a hardware/deep-tech emphasis than Bison.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/bisonvc

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments17 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bison Ventures