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Endotronix

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uuid0000kym

Namestring
Endotronix
Legal namestring
Endotronix, Inc.
Websiteurl
endotronix.com
Company typeenum
Private
Founded yearint
2017
Short descriptiontext

Endotronix develops the FDA-approved Cordella Pulmonary Artery Sensor System, an implantable MEMS-based device for remote hemodynamic monitoring of NYHA Class III heart failure patients. Acquired by Edwards Lifesciences in August 2024, it now operates as a wholly owned subsidiary.

Operating statusenum
Acquired
Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersLisle, United States
HQ citystring
Lisle
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices3 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
implantable heart sensors, hemodynamic monitoring systems, heart failure management, pulmonary artery pressure monitoring, remote patient monitoring
Industry4 codes
1Hemodynamic Monitoring & Cardiac Diagnostics (Cath Lab, FFR/IVUS/OCT)
CodeHLAHAFAIPrimaryYes
2Cardiac Assist & Heart Failure Therapies (Implantables, Neuromodulation)
CodeHLAHAFALPrimaryNo
3Cardiometabolic RPM & Chronic Disease Management (diabetes, hypertension, CHF, obesity)
CodeHLALAFAAPrimaryNo
4Medical-Grade Device Connectivity & Device Management (MDM)
CodeHLACAFAGPrimaryNo
NAICS code3 codes
  • Electromedical and Electrotherapeutic Apparatus Manufacturing334510
  • Navigational, Measuring, Electromedical, and Control Instruments Manufacturing3345
  • Surgical and Medical Instrument Manufacturing339112
SIC code2 codes
  • Electromedical & Electrotherapeutic Apparatus3845
  • Surgical & Medical Instruments & Apparatus3841
Product category
Implantable Cardiac Hemodynamic Monitoring
GTM motion2 records

Each record includes

Type, Description, Source

Revenue model3 records
1Cordella PA Sensor Implant
TypeHardware Sales
Description

One-time sale of implantable pulmonary artery pressure sensor for heart failure patients. The sensor is implanted during a catheterization procedure and provides long-term pressure monitoring. Revenue recognized upon device implantation.

endotronix.com
2Remote Patient Monitoring Services
TypeSubscription Recurring
Description

Ongoing remote monitoring services supported by Medicare reimbursement codes including remote monitoring of wireless pulmonary artery pressure sensor and principal/chronic care management (P/CCM). Clinicians bill for clinically necessary services that improve patient monitoring and care coordination.

endotronix.com
3Cordella HF System Platform
TypeSubscription Recurring
Description

System includes patient reader, docking station, and cloud platform for data transmission and clinical review. May involve subscription or per-patient pricing for healthcare provider access to the management platform.

endotronix.com
Marketing channels6 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels3 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components6 values
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Others
Pricing details1 tier
1Medicare reimbursement codes support remote PA pressure monitoring and chronic care management
ModelSubscriptionBilling cadencePer patient encounter
Notes

In the US, Medicare reimbursement supports remote management for ambulatory heart failure patients. New codes such as remote monitoring of wireless pulmonary artery pressure sensor and principal/chronic care management (P/CCM) enable providers to bill for services.

endotronix.com
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Brand1 of 2 records shown
1Cordella
Description

FDA-approved Pulmonary Artery Sensor and Heart Failure System for NYHA Class III heart failure patients, enabling remote hemodynamic monitoring

endotronix.com
+1 more record
Core offering1 text field

Endotronix develops and commercializes the Cordella Pulmonary Artery Sensor System, an FDA-approved implantable medical device that continuously measures, records, and transmits pulmonary artery pressure data from NYHA Class III heart failure patients at home. The system pairs the implantable MEMS-based sensor with a handheld patient reader and a cloud-connected heart failure management platform (myCordella) that integrates vital signs, symptoms, and trend data to enable clinician-directed proactive care and remote medication optimization.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 11 values shown
  • 73% reduction in HF hospitalization rate before and after Cordella use at 12 months
+10 more records
Product overview1 text field

Endotronix offers a single unified product—the Cordella Heart Failure System—for remote hemodynamic monitoring of heart failure patients. The system comprises three core components: the FDA-approved Cordella PA Sensor (an implantable MEMS-based pulmonary artery pressure sensor), the Cordella Delivery System (for sensor implantation), and the Cordella Patient Reader/Hub (handheld device for daily patient readings). These are integrated into a comprehensive patient management platform that includes the myCordella Hub tablet application for vital sign collection (blood pressure, weight, oxygen, pulse, symptoms) and secure clinician communication. The system is designed for NYHA Class III heart failure patients and enables proactive, PA pressure-guided management to reduce hospitalizations and improve outcomes.

Product and service2 records
1Cordella Pulmonary Artery Sensor System
CategoryImplantable Cardiac Hemodynamic Monitoring
Description

FDA-approved implantable pulmonary artery pressure sensor system for NYHA Class III heart failure patients, comprising an implanted MEMS-based sensor, a handheld patient reader, and a cloud-based HF management platform that allows clinicians to monitor patients at home and guide treatment decisions.

2CordellaCares Patient Access Program
Scale indicator14 records

Each record includes

Type, Value, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Abbott's CardioMEMS HF System is the direct, FDA-approved, commercially entrenched competitor to Cordella — an implantable PA pressure sensor for NYHA Class III heart failure patients supported by the CHAMPION trial. CardioMEMS defines the incumbent standard Cordella must displace in heart failure clinics.

TypeEmerging player
Description

Israel-based developer of the V-LAP, a second-generation left atrial pressure (LAP) sensor implant for heart failure management. Competes head-to-head with Cordella in the wireless implantable hemodynamic monitoring category, with overlapping customer base of heart failure specialists.

TypeBroad incumbent
Description

Diversified medtech incumbent with a heart failure portfolio (including cardiac resynchronization, ICDs, and remote monitoring via CareLink). Competes for the same hospital budget, heart failure specialist relationships, and remote-monitoring reimbursement codes that Cordella targets.

TypeBroad incumbent
Description

Large cardiovascular medtech with heart failure diagnostics and remote monitoring offerings (e.g., LATITUDE patient management system) and structural heart therapies. Overlaps with Cordella in serving advanced heart failure patients and the cardiology channel.

TypeBroad incumbent
Description

Structural heart and critical care medtech leader that acquired Endotronix in August 2024. The relevant comparison is at the parent-portfolio level — Edwards' own heart failure, transcatheter, and monitoring franchises share channels and customers with Cordella.

TypeEmerging player
Description

Developer of a non-invasive cardiac scale for at-home hemodynamic monitoring in heart failure patients. Competes for the same NYHA Class III patient and reimbursement dollars as Cordella, with a fundamentally different (non-implant) workflow that could constrain Cordella adoption if it gains traction.

TypeEmerging player
Description

Non-invasive cardiac output and hemodynamic assessment technology. Targets the same heart failure patient and clinician audience as Cordella with a non-implant workflow, making it a long-tail substitute on the diagnostic-monitoring side of heart failure management.

TypeBroad incumbent
Description

Large imaging, monitoring, and diagnostics incumbent with a portfolio spanning cardiac diagnostics, hospital patient monitoring, and EMR/clinical workflow software. Overlaps with Cordella in hospital procurement, EMR integration, and cardiology department relationships.

TypeBroad incumbent
Description

Global health technology incumbent in cardiac monitoring, connected care, and remote patient management. Overlaps with Cordella in hospital patient monitoring, RPM platforms, and the cardiology channel — and competes for telehealth/RPM budget allocations in heart failure programs.

TypeEmerging player
Description

Digital stethoscope and AI-enabled cardiac auscultation company expanding into heart failure screening and remote cardiac monitoring. A partial-overlap emerging player that targets the same cardiologists and HF patients with non-invasive, lower-cost workflow alternatives to implantable hemodynamic sensors.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Named customers3 records

Each record includes

Name, Industry, Type, Use case, Source, UUID

Segment3 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

Integration1 record

Each record includes

Title, Type, Description, Source

AI maturity
App detail

Has app

Feature4 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
No data
Compliance1 record

Each record includes

Name, Class, Description

Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds10 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors12 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Endotronix

Implantable Cardiac Hemodynamic Monitoringendotronix.com

Endotronix develops the FDA-approved Cordella Pulmonary Artery Sensor System, an implantable MEMS-based device for remote hemodynamic monitoring of NYHA Class III heart failure patients. Acquired by Edwards Lifesciences in August 2024, it now operates as a wholly owned subsidiary.

Endotronix firmographics

Firmographics
Name
Endotronix
Legal name
Endotronix, Inc.
Website
https://endotronix.com
Company type
Private
Founded year
2017
Operating status
Acquired
Headcount range
101–250 employees
Short description
Endotronix develops the FDA-approved Cordella Pulmonary Artery Sensor System, an implantable MEMS-based device for remote hemodynamic monitoring of NYHA Class III heart failure patients. Acquired by Edwards Lifesciences in August 2024, it now operates as a wholly owned subsidiary.
Ownership category
akta.pro rank

Endotronix industry classification

Industry
Product category
Implantable Cardiac Hemodynamic Monitoring
NAICS
Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (3345), Surgical and Medical Instrument Manufacturing (339112)
SIC
Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)
akta.pro primary industry
Hemodynamic Monitoring & Cardiac Diagnostics (Cath Lab, FFR/IVUS/OCT) (HLAHAFAI)
akta.pro secondary industries
Cardiac Assist & Heart Failure Therapies (Implantables, Neuromodulation) (HLAHAFAL), Cardiometabolic RPM & Chronic Disease Management (diabetes, hypertension, CHF, obesity) (HLALAFAA), Medical-Grade Device Connectivity & Device Management (MDM) (HLACAFAG)

Keywords

  • Implantable heart sensors
  • Hemodynamic monitoring systems
  • Heart failure management
  • Pulmonary artery pressure monitoring
  • Remote patient monitoring

Where Endotronix is headquartered

Location

Headquarters

HQ city
Lisle
HQ country
United States
HQ region
North America

Offices3 records

Markets served

Endotronix business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Others

Revenue model

  1. Cordella PA Sensor Implant: One-time sale of implantable pulmonary artery pressure sensor for heart failure patients. The sensor is implanted during a catheterization procedure and provides long-term pressure monitoring. Revenue recognized upon device implantation.
  2. Remote Patient Monitoring Services: Ongoing remote monitoring services supported by Medicare reimbursement codes including remote monitoring of wireless pulmonary artery pressure sensor and principal/chronic care management (P/CCM). Clinicians bill for clinically necessary services that improve patient monitoring and care coordination.
  3. Cordella HF System Platform: System includes patient reader, docking station, and cloud platform for data transmission and clinical review. May involve subscription or per-patient pricing for healthcare provider access to the management platform.

Pricing tiers

ModelBillingPrice
SubscriptionPer patient encounterMedicare reimbursement codes support remote PA pressure monitoring and chronic care management

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Endotronix product offering

Product offering

Core offering

Endotronix develops and commercializes the Cordella Pulmonary Artery Sensor System, an FDA-approved implantable medical device that continuously measures, records, and transmits pulmonary artery pressure data from NYHA Class III heart failure patients at home. The system pairs the implantable MEMS-based sensor with a handheld patient reader and a cloud-connected heart failure management platform (myCordella) that integrates vital signs, symptoms, and trend data to enable clinician-directed proactive care and remote medication optimization.

Product overview

Endotronix offers a single unified product—the Cordella Heart Failure System—for remote hemodynamic monitoring of heart failure patients. The system comprises three core components: the FDA-approved Cordella PA Sensor (an implantable MEMS-based pulmonary artery pressure sensor), the Cordella Delivery System (for sensor implantation), and the Cordella Patient Reader/Hub (handheld device for daily patient readings). These are integrated into a comprehensive patient management platform that includes the myCordella Hub tablet application for vital sign collection (blood pressure, weight, oxygen, pulse, symptoms) and secure clinician communication. The system is designed for NYHA Class III heart failure patients and enables proactive, PA pressure-guided management to reduce hospitalizations and improve outcomes.

Differentiator

Problem solved

Functional benefit

Brands

  • Cordella: FDA-approved Pulmonary Artery Sensor and Heart Failure System for NYHA Class III heart failure patients, enabling remote hemodynamic monitoring
  • myCordella

Products and services

  • Cordella Pulmonary Artery Sensor System FDA-approved implantable pulmonary artery pressure sensor system for NYHA Class III heart failure patients, comprising an implanted MEMS-based sensor, a handheld patient reader, and a cloud-based HF management platform that allows clinicians to monitor patients at home and guide treatment decisions.
  • CordellaCares Patient Access Program

Quantifiable outcome

  • 73% reduction in HF hospitalization rate before and after Cordella use at 12 months
  • +10 more outcomes

Companies that use Endotronix

Customer profile

Named customers3 records

Segments3 records

Ideal customer profiles2 records

Endotronix technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Integration1 record

Feature4 records

Endotronix partnerships and signals

Strategic signal

Scale indicators14 records

Expansion highlights5 records

Endotronix competitors and assessment

Company assessment

Direct peers

  • Abbott: Abbott's CardioMEMS HF System is the direct, FDA-approved, commercially entrenched competitor to Cordella — an implantable PA pressure sensor for NYHA Class III heart failure patients supported by the CHAMPION trial. CardioMEMS defines the incumbent standard Cordella must displace in heart failure clinics.

Emerging players

  • Vectorious Medical Technologies: Israel-based developer of the V-LAP, a second-generation left atrial pressure (LAP) sensor implant for heart failure management. Competes head-to-head with Cordella in the wireless implantable hemodynamic monitoring category, with overlapping customer base of heart failure specialists.
  • Bodyport: Developer of a non-invasive cardiac scale for at-home hemodynamic monitoring in heart failure patients. Competes for the same NYHA Class III patient and reimbursement dollars as Cordella, with a fundamentally different (non-implant) workflow that could constrain Cordella adoption if it gains traction.
  • Sensydia: Non-invasive cardiac output and hemodynamic assessment technology. Targets the same heart failure patient and clinician audience as Cordella with a non-implant workflow, making it a long-tail substitute on the diagnostic-monitoring side of heart failure management.
  • Eko Health: Digital stethoscope and AI-enabled cardiac auscultation company expanding into heart failure screening and remote cardiac monitoring. A partial-overlap emerging player that targets the same cardiologists and HF patients with non-invasive, lower-cost workflow alternatives to implantable hemodynamic sensors.

Broad incumbents

  • Medtronic: Diversified medtech incumbent with a heart failure portfolio (including cardiac resynchronization, ICDs, and remote monitoring via CareLink). Competes for the same hospital budget, heart failure specialist relationships, and remote-monitoring reimbursement codes that Cordella targets.
  • Boston Scientific: Large cardiovascular medtech with heart failure diagnostics and remote monitoring offerings (e.g., LATITUDE patient management system) and structural heart therapies. Overlaps with Cordella in serving advanced heart failure patients and the cardiology channel.
  • Edwards Lifesciences: Structural heart and critical care medtech leader that acquired Endotronix in August 2024. The relevant comparison is at the parent-portfolio level — Edwards' own heart failure, transcatheter, and monitoring franchises share channels and customers with Cordella.
  • GE HealthCare: Large imaging, monitoring, and diagnostics incumbent with a portfolio spanning cardiac diagnostics, hospital patient monitoring, and EMR/clinical workflow software. Overlaps with Cordella in hospital procurement, EMR integration, and cardiology department relationships.
  • Philips: Global health technology incumbent in cardiac monitoring, connected care, and remote patient management. Overlaps with Cordella in hospital patient monitoring, RPM platforms, and the cardiology channel — and competes for telehealth/RPM budget allocations in heart failure programs.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

Endotronix social profiles

Digital presence

Endotronix compliance and trust

Trust signal

Compliance1 record

Endotronix financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Endotronix leadership team

Management profile

Number of profiles

Endotronix funding detail

Funding detail

Funding overview

Funding rounds10 records

Investors12 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Endotronix M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Endotronix

What does Endotronix do?

Endotronix develops and commercializes the Cordella Pulmonary Artery Sensor System, an FDA-approved implantable medical device that continuously measures, records, and transmits pulmonary artery pressure data from NYHA Class III heart failure patients at home. The system pairs the implantable MEMS-based sensor with a handheld patient reader and a cloud-connected heart failure management platform (myCordella) that integrates vital signs, symptoms, and trend data to enable clinician-directed proactive care and remote medication optimization.

Is Endotronix a public or private company?

Endotronix is a private company. It is classified as corporate owned and is currently acquired.

When was Endotronix founded?

Endotronix was founded in 2017. It employs 101 to 250 people.

Where is Endotronix based?

Endotronix is headquartered in Lisle, United States, in the North America region.

How does Endotronix make money?

Three revenue lines are on record. Cordella PA Sensor Implant is the primary driver. The others are remote Patient Monitoring Services and cordella HF System Platform.

Who are Endotronix's main competitors?

Abbott is listed as a direct peer. Emerging players are Vectorious Medical Technologies, Bodyport, Sensydia and Eko Health. Broad incumbents are Medtronic, Boston Scientific, Edwards Lifesciences, GE HealthCare and Philips.

Does Endotronix have an API?

No public API is recorded for Endotronix.

What industry is Endotronix in?

Endotronix's product category is Implantable Cardiac Hemodynamic Monitoring. Its primary akta.pro industry code is HLAHAFAI, Hemodynamic Monitoring & Cardiac Diagnostics (Cath Lab, FFR/IVUS/OCT), with a secondary code of HLAHAFAL, Cardiac Assist & Heart Failure Therapies (Implantables, Neuromodulation). Its NAICS code is 334510 and its SIC code is 3845.

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Live signals
The Daily RecordMD heart care advances with minimally invasive tech, clinical trialsThree Maryland healthcare organizations are advancing heart care through remote monitoring technology and minimally invasive procedures: the University of Maryland Medical System has been implanting FDA-approved CardioMEMS devices since 2022 for remote pulmonary artery pressure monitoring, while the UM Center for Aortic Disease performs complex procedures including the Endo-Bentall and TAMBE using 3D-printed patient-specific models. MedStar Health is conducting over 30 cardiovascular clinical trials evaluating devices including Abbott's Navitor Vision TAVR valve and Endotronix's Cordella pulmonary artery sensor, aiming to expand access to minimally invasive heart valve replacements. Cardiovascular disease remains the leading cause of death in the U.S., accounting for more than 25% of all deaths in 2023.PR NewswireLES DONNÉES À UN AN MONTRENT D'EXCELLENTS RÉSULTATS POUR LE SYSTÈME DE CAPTEUR D'ARTÈRE PULMONAIRE CORDELLA D'ENDOTRONIXEndotronix, a subsidiary of Edwards Lifesciences, reported one-year clinical results from the PROACTIVE-HF study showing that its Cordella pulmonary artery sensor system significantly reduced heart failure hospitalization and mortality rates. The data indicated a 49% reduction in combined events compared to pre-specified thresholds, alongside improvements in patient quality of life and biomarker levels.PR NewswireExcelentes resultados del sistema de sensor de arteria pulmonar Endotronix de CordellaEndotronix, a company of Edwards Lifesciences, announced one-year results from the PROACTIVE-HF clinical trial evaluating the Cordella pulmonary artery sensor system, with data presented at the HFSA Annual Scientific Meeting. The trial of 456 patients showed a 49% reduction in heart failure hospitalizations and all-cause mortality (36 events per 100 patients versus 70 expected). Secondary endpoints demonstrated significant improvements in quality of life metrics and biomarker levels, including a 5.7-point improvement in the Kansas City Cardiomyopathy Questionnaire and a 5.7% reduction in NT-proBNP levels.PR NewswireEIN-JAHRES-DATEN ZEIGEN HERVORRAGENDE ERGEBNISSE FÜR DAS CORDELLA PULMONALARTERIEN-SENSORSYSTEM VON ENDOTRONIXEndotronix, a company owned by Edwards Lifesciences, announced 1-year clinical results from the PROACTIVE-HF study evaluating the Cordella Pulmonary Artery Sensor System in 456 heart failure patients. The study demonstrated a 49% reduction in heart failure hospitalizations and overall mortality rates (36 events per 100 patients versus the预设的70 events per 100 patients), alongside significant improvements in quality of life, exercise capacity, and biomarkers including a 5.7% reduction in NT-proBNP levels.BenzingaEdwards Lifesciences Stock Tumbles, Highlights Slowdown In TAVR Business - Edwards Lifesciences (NYSE:EW)Edwards Lifesciences reported second-quarter adjusted EPS of 70 cents, beating consensus, but sales of $1.632 billion fell short of expectations due to slower-than-anticipated TAVR growth. The company lowered its full-year TAVR growth guidance to 5%-7% from 8-10%, citing hospital workflow pressures rather than competitive losses, while simultaneously acquiring JenaValve Technology and exercising options for Endotronix. Analysts view the procedural demand constraints as validation for Edwards' broader structural heart therapies despite the near-term headwind.BenzingaWhy Edwards Lifesciences Shares Are Trading Lower? Here Are Other Stocks Moving In Thursday's Mid-Day SesEdwards Lifesciences shares fell 26.9% to $63.60 after the company reported second-quarter sales of $1.632 billion, missing analyst estimates, and issued third-quarter guidance below expectations. Despite beating earnings per share consensus with 70 cents per share, the negative outlook drove the sharp decline. The company also announced acquisitions of JenaValve and Endotronix.QuantisnowEdwards Lifesciences Expands Structural Heart Portfolio With Acquisitions of JenaValve and EndotronixEdwards Lifesciences announced a $1.2 billion strategic investment to acquire JenaValve Technology and exercise its option to purchase Endotronix, expanding its structural heart portfolio into aortic regurgitation and heart failure treatments. The acquisitions aim to address significant unmet patient needs, with Edwards anticipating FDA approval for the JenaValve system in late 2025 and minimal immediate revenue contribution from the deals.Mpo-magEdwards to Buy JenaValve & Endotronix for $1.2BEdwards Lifesciences announced the acquisition of JenaValve and the exercise of its option to acquire Endotronix for an aggregate upfront price of approximately $1.2 billion. These transactions aim to expand Edwards' portfolio into structural heart therapeutic areas, specifically targeting aortic regurgitation and heart failure management. The companies expect minimal revenue contribution from these deals in 2025, with key regulatory approvals anticipated later that year.PR NewswireEndotronix recibe la aprobación IDE para el ensayo clínico de ampliación de mercado PROACTIVE-HF 2Endotronix, Inc. received FDA Investigational Device Exemption (IDE) approval for the PROACTIVE-HF 2 clinical trial to evaluate its Cordella pulmonary artery pressure sensor in heart failure patients. The multicenter trial will enroll up to 1,500 patients in the US and Europe, expanding access to NYHA Class II patients and comparing pressure-guided therapy against a telehealth control arm. The company also presented positive 12-month substudy data from its pivotal PROACTIVE-HF trial showing a low heart failure hospitalization rate of 0.34 and significant reductions in mean pulmonary artery pressure, with PMA submission to the FDA planned for year-end.PR NewswireEndotronix reçoit l'approbation IDE pour l'essai clinique PROACTIVE-HF 2 qui élargit le marchéEndotronix received FDA IDE approval for the PROACTIVE-HF 2 multicenter clinical trial, which will evaluate the Cordella sensor for pulmonary artery pressure-guided therapy in NYHA Class II heart failure patients with up to 1,500 patients in the US and Europe. The company also presented positive 12-month substudy data from its pivotal PROACTIVE-HF trial showing a low hospitalization rate of 0.34 at 12 months and significant improvements in mean pulmonary artery pressure among Class III NYHA patients. Endotronix plans to submit a PMA application to the FDA by year-end and targets a mid-2024 commercial launch for Cordella.