House Rx
House Rx is a San Francisco health technology company that partners with oncology and rheumatology practices to dispense specialty medications in-clinic, using an AI-enabled pharmacy management platform integrated with practice EHRs to accelerate prior authorizations, reduce fulfillment times, and improve medication adherence.
- Company typePrivate
- Founded2021
- HeadquartersSan Francisco, United States
- Headcount51–100
- GTM typeB2B
- OfferingSoftware
What House Rx does
House Rx is a health technology and pharmacy services company founded in 2021 and headquartered in San Francisco that enables medically integrated dispensing of specialty medications inside oncology and rheumatology practices. The company deploys House Rx pharmacists and care coordinators directly into partner clinics, where they dispense oral specialty drugs as part of the patient's care team rather than routing prescriptions through external PBM-owned specialty pharmacies. This model targets the structural friction in traditional specialty pharmacy, including prior authorization delays of three to four weeks, mail-order fulfillment cycles averaging 27 days, medication adherence rates around 70%, and patient financial toxicity from high out-of-pocket costs.
The core product is a cloud-based pharmacy management platform, built by specialty pharmacists and physicians, that integrates with practice EHR systems to connect prescribers and pharmacists on a shared workflow. The platform comprises several modules: Script Management for prescription processing, Prior Authorization Automation using AI to consolidate data and pre-populate forms, Financial Assistance Workflows for copay and grant enrollment, Dispensing Analytics Dashboards for operational metrics, Patient Engagement Tools including pharmacist chat and refill coordination, and Drug Utilization Review for automated safety checking. In April 2025 the company announced what it describes as the first AI-enabled pharmacy management platform, incorporating HIPAA-compliant AI agents that automate eligibility verification, PA submission, and financial assistance enrollment. Underlying integrations include First Databank for drug data, Surescripts for eligibility and e-prescribing, CoverMyMeds for prior authorization services, and Moov for payment processing.
House Rx generates revenue through two primary streams: recurring program fees from partner clinics for managing medically integrated dispensing programs (with a contractual minimum of $1,000 per month per MID location) and subscription licensing of the pharmacy management platform technology. Distribution is direct-to-practice, with a field sales model targeting specialty clinics and channel expansion through industry advisors. By November 2025 the company operated across 80 clinic sites with 1,000+ providers, processing $1.5 billion in specialty prescriptions annually with a stated target to reach $3 billion by end of 2026, supported by approximately $100 million in total venture funding.
House Rx firmographics
Firmographics- Name
- House Rx
- Legal name
- House Rx, Inc.
- Website
- https://houserx.com
- Company type
- Private
- Founded year
- 2021
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- House Rx is a San Francisco health technology company that partners with oncology and rheumatology practices to dispense specialty medications in-clinic, using an AI-enabled pharmacy management platform integrated with practice EHRs to accelerate prior authorizations, reduce fulfillment times, and improve medication adherence.
- Ownership category
- akta.pro rank
House Rx industry classification
Industry- Product category
- Specialty Pharmacy Management Software
- NAICS
- Offices of Physicians (62111), Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- Virtual Pharmacy & Medication Management Integration Platforms (HLALABAL)
- akta.pro secondary industry
- PBM Technology Platforms (ePA/eRx/Real-Time Benefit Tools) (HLAEAKAL)
Keywords
Where House Rx is headquartered
LocationHeadquarters
- HQ city
- San Francisco
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
House Rx business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure
Revenue model
- Pharmacy Services & MID Program Fees: House Rx charges partner clinics program fees for implementing and managing medically integrated dispensing programs. The company provides turnkey pharmacy services including pharmacist staffing, pharmacy management technology, and operational support in exchange for recurring service fees.
- Technology Platform Licensing: Revenue generated from licensing the proprietary pharmacy management platform to partner clinics, including EHR integration tools, analytics dashboards, and patient engagement features.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Monthly | Program fees for medically integrated dispensing services |
Go-to-market motion2 records
Distribution channels1 record
Marketing channels8 records
House Rx product offering
Product offeringCore offering
House Rx provides a cloud-based pharmacy management platform that enables specialty medical practices to dispense medications directly to patients in a medically integrated model. The company partners with oncology, rheumatology, and other specialty clinics to deliver turnkey in-clinic pharmacy services including pharmacist staffing, EHR-integrated technology, prior authorization automation, financial assistance workflows, and operational support in exchange for recurring program fees.
Product overview
House Rx offers a unified cloud-based pharmacy management platform designed specifically for medically integrated dispensing in specialty clinics. The core House Rx Platform serves as the central system, integrating with clinic EHRs to connect prescribers and pharmacists. The platform comprises several integrated modules: Script Management for prescription processing, Dispensing Analytics Dashboards for operational insights, Prior Authorization Automation for AI-driven PA workflows, Patient Engagement Tools for scalable outreach, Financial Assistance Workflows for copay and grant support, and Drug Utilization Review for safety checking. Together, these components enable clinics to dispense specialty medications in-house while maintaining 95% medication adherence rates and reducing total healthcare costs by 13%.
Differentiator
Problem solved
Functional benefit
Products and services
- House Rx Platform Cloud-based pharmacy management platform built by specialty pharmacists and physicians that enables medically integrated dispensing. Integrates with clinic EHRs to support prior authorization, financial counseling, fulfillment, patient engagement, and real-time analytics for specialty medical practices.
- Script Management Module within the House Rx Platform that manages specialty medication prescriptions from receipt through fulfillment, enabling pharmacists and care coordinators to process scripts efficiently within the integrated care team workflow.
- Prior Authorization Automation AI-powered workflow automation that consolidates data from multiple sources, pre-populates authorization forms, tracks status, and sends renewal reminders to reduce administrative burden and avoid treatment gaps for specialty clinics.
- Financial Assistance Workflows Automation tools that screen patient eligibility, enroll patients in financial assistance programs, track grants and foundations, and optimize copays to reduce financial barriers to specialty therapy.
- Drug Utilization Review Clinical decision support module integrated with EHR data that automatically checks drug contraindications against patient allergies, medications, diagnoses, age, and pregnancy status and flags exceptions for pharmacist review.
- Dispensing Analytics Dashboards Real-time analytics dashboards built into the House Rx Platform that surface actionable insights from clinic dispensing data, tracking operational and quality metrics to optimize dispensing and clinical operations.
- Patient Engagement Tools Scalable patient engagement features including private chat/text with pharmacists, proactively coordinated refills, copay processing, pickup/delivery coordination, and digital side-effect and adherence monitoring.
- AI-Enabled Pharmacy Management Platform First AI-enabled pharmacy management platform announced in April 2025, incorporating artificial intelligence to automate prior authorization workflows, benefit investigation, and financial assistance enrollment for specialty clinics.
Quantifiable outcome
- 95% medication adherence rate observed in medically integrated dispensing model as compared to 70% in traditional specialty pharmacy
- +6 more outcomes
Companies that use House Rx
Customer profileNamed customers15 records
Segments3 records
Ideal customer profiles1 record
House Rx technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration4 records
AI capability4 records
Feature8 records
House Rx partnerships and signals
Strategic signalPartnerships
Ten partnerships are on record, tiered core and advisory.
- First Databank, Inc.coreLicensed FDB Databases of medical, pharmaceutical and nutritional information for sublicense to House Rx customers as part of the pharmacy management platform.
- Relay Health / SurescriptscoreLicensed services for pharmacy benefit management data and eligibility verification through the Surescripts network.
- CoverMyMedscoreLicensed prior authorization services including PA assistance, benefit verification, patient financial assistance, and prescription management.
- MoovcoreLicensed financial technology platform for payment processing and ACH transfers related to pharmacy transactions.
- Jeff Hunnicutt (Highlands Oncology Group)advisoryCEO of Highlands Oncology Group serving as advisor. Provides strategic guidance on medically integrated dispensing from frontline oncology practice perspective.
- Josh Cox, PharmD, BCPS (Dayton Physicians Network)advisoryDirector of Pharmacy and Research at Dayton Physicians Network serving as advisor. Brings pharmacy operations and clinical expertise.
- Alti Rahman (American Oncology Network)advisoryChief Strategy & Innovation Officer at American Oncology Network serving as advisor on specialty pharmacy strategy.
- Bob Phelan (Cancer Specialists of North Florida)advisoryCEO of Cancer Specialists of North Florida serving as advisor on oncology practice operations.
- Bobby Green, MD (Thyme Care)advisoryPresident & Chief Medical Officer of Thyme Care serving as advisor on care coordination and clinical quality.
- Mark Nelson, PharmD (Northwest Medical Specialties)advisoryCEO of Northwest Medical Specialties serving as advisor on pharmacy integration and practice management.
Scale indicators13 records
Recent moves8 records
Expansion highlights6 records
House Rx competitors and assessment
Company assessmentEmerging players
- Alto Pharmacy: Alto Pharmacy is a digital pharmacy platform focused on patient experience, free same-day delivery, and provider-friendly technology. While not clinic-embedded, it competes for specialty pharmacy share via technology-driven convenience and price transparency, overlapping with House Rx's technology-first, patient-centric approach.
- Arine: Arine is an AI-driven medication management platform serving health plans and providers to optimize medication therapy and adherence. It is comparable to House Rx in applying AI/automation to pharmacy and medication management workflows, though Arine is payer-focused rather than provider/clinic-embedded.
- Capsule: Capsule is a digital-first pharmacy offering same-day delivery and a technology-driven patient experience. It overlaps with House Rx in offering an alternative to traditional specialty pharmacy via technology, though Capsule is consumer-facing and primarily retail/specialty rather than clinic-embedded.
Broad incumbents
- Biologics by McKesson: Biologics by McKesson is an established specialty pharmacy focused on oncology, rheumatology, and other specialty conditions. As a McKesson-owned pharmacy, it operates at broader scale than House Rx and represents the incumbent distribution-and-specialty-pharmacy model House Rx's decentralized clinic-embedded approach challenges.
- US Bioservices (AmerisourceBergen / Cencora): US Bioservices, part of Cencora (formerly AmerisourceBergen), is a specialty pharmacy serving patients with chronic and complex conditions. It competes with House Rx in dispensing specialty medications and provides clinical and adherence support, but operates via centralized mail-order rather than clinic-embedded dispensing.
- CVS Specialty (Caremark): CVS Specialty, part of CVS Health, is one of the largest specialty pharmacy providers and is closely tied to the Caremark PBM. It represents the incumbent PBM-owned specialty pharmacy model that House Rx explicitly positions against as a decentralized alternative.
Direct peers
- Onco360: Onco360 is a specialty pharmacy focused on oncology and other complex conditions, providing oral oncolytic dispensing, patient education, and adherence support. While not clinic-embedded in the same way as House Rx, it competes for the same oncology specialty prescription volume and similar clinical outcomes.
- Trellis Rx (CPS Solutions): Trellis Rx (acquired by CPS Solutions) is a direct peer that provides technology-enabled specialty pharmacy services embedded in hospital outpatient clinics. Both companies focus on medically integrated dispensing for high-cost specialty drugs, leveraging EHR-integrated platforms to manage prior authorization and patient support.
- Shields Health Solutions: Shields Health Solutions is a direct peer — it partners with hospital systems and health systems to build and operate in-clinic/outpatient specialty pharmacies, with a similar model of embedding pharmacists into provider workflows and technology-enabled dispensing. Both target complex specialty medications and emphasize adherence and clinical outcomes.
Others
- RxBenefits: RxBenefits is a pharmacy benefits administrator focused on self-funded employer health plans, providing PBM procurement and management services. While not a direct dispensing competitor, it operates in the specialty pharmacy value chain and represents a potential partner or adjacent player for House Rx's specialty pharmacy services.
Market position
Strengths5 records
Weaknesses4 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
House Rx social profiles
Digital presenceHouse Rx financial estimates
Financial estimateRevenue estimate
Valuation estimate
House Rx leadership team
Management profileNumber of profiles
Profiles14 records
House Rx funding detail
Funding detailFunding overview
Funding rounds4 records
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
House Rx M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about House Rx
What does House Rx do?
House Rx provides a cloud-based pharmacy management platform that enables specialty medical practices to dispense medications directly to patients in a medically integrated model. The company partners with oncology, rheumatology, and other specialty clinics to deliver turnkey in-clinic pharmacy services including pharmacist staffing, EHR-integrated technology, prior authorization automation, financial assistance workflows, and operational support in exchange for recurring program fees.
Is House Rx a public or private company?
House Rx is a private company. It is classified as venture growth investor backed and is currently operating.
When was House Rx founded?
House Rx was founded in 2021. It employs 51 to 100 people.
Where is House Rx based?
House Rx is headquartered in San Francisco, United States, in the North America region.
How does House Rx make money?
Two revenue lines are on record. Pharmacy Services & MID Program Fees are the primary driver. The others are technology Platform Licensing.
Who are House Rx's main competitors?
Emerging players on record are Alto Pharmacy, Arine and Capsule. Broad incumbents are Biologics by McKesson, US Bioservices (AmerisourceBergen / Cencora) and CVS Specialty (Caremark). Direct peers are Onco360, Trellis Rx (CPS Solutions) and Shields Health Solutions. RxBenefits is listed as an others.
Does House Rx have an API?
No public API is recorded for House Rx.
What industry is House Rx in?
House Rx's product category is Specialty Pharmacy Management Software. Its primary akta.pro industry code is HLALABAL, Virtual Pharmacy & Medication Management Integration Platforms, with a secondary code of HLAEAKAL, PBM Technology Platforms (ePA/eRx/Real-Time Benefit Tools). Its NAICS code is 62111 and its SIC code is 7372.