What one.bio does

one.bio is a Sacramento-based biotechnology company founded in 2019 as a spinout of UC Davis, operating as a fiber science platform under parent entity One Unlimited. The company builds a proprietary data asset called the Glycopedia, which maps dietary fiber molecular structures to gut microbiome fermentation pathways and specific biological outcomes (inflammation reduction, beneficial bacteria feeding, gut barrier strengthening, immune signaling). This database underpins a portfolio of formulated fiber ingredients, of which one.bio 01 is the clinically validated lead product—a prebiotic oat fiber with documented digestive comfort, blood sugar stabilization, and mood outcomes in a 14-day, 63-adult clinical study. The company's formulation science is positioned around 'invisible' fiber technology, enabling high-dose fiber addition (up to 50g) in foods and beverages without affecting taste, texture, or color.

The business operates a dual go-to-market: B2B ingredient sales of one.bio 01 to food and beverage manufacturers, and direct-to-consumer sales through GoodVice, a wholly owned consumer protein shake brand launched in February 2026 via DrinkGoodVice.com. GoodVice functions as a visible reference design and proof-of-concept for the underlying fiber platform, with 10g of prebiotic oat fiber and 15g of grass-fed milk protein per serving. The company is venture-backed, having raised approximately $44 million across a 2019 Gates Foundation grant and three equity rounds (2020, 2022, 2024), with the $27M Series A in December 2024 led by Alpha Edison and including strategic investors Leaps by Bayer and DSM-Firmenich Venturing. Co-founders are Matt Amicucci, PhD (CSO, UC Davis-originated Glycopedia research) and Matt Barnard (CEO, prior vertical-farming operator), supported by co-founders David Mills, Bruce German, and Carlito Lebrilla, and a President (Steven Watkins).

Name

one.bio

Website

https://one.bio

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

11–50 employees

Short description

one.bio is a UC Davis spinout building a fiber science platform anchored by the Glycopedia database, which maps fiber molecular structures to gut microbiome outcomes and underpins clinically validated prebiotic oat fiber ingredients sold B2B to food and beverage manufacturers and D2C through its GoodVice brand.

Ownership category

akta.pro rank

Product category

Prebiotic Fiber Ingredients

NAICS

Dairy Product (except Frozen) Manufacturing (31151), Food Manufacturing (311)

SIC

Dairy Products (2020), Miscellaneous Food Preparations & Kindred Products (2090)

akta.pro primary industry

Prebiotics & Dietary Fibers (Inulin, FOS/GOS, Resistant Starch, Beta-Glucan, Psyllium) (AFAJAKAF)

akta.pro secondary industries

Probiotic, Prebiotic & Gut-Health Foods Manufacturing (Fermented Functional Foods, Synbiotics) (AFAKAJAH), Probiotic/Prebiotic Functional Beverage Production (Non-Fermented) (AFAFAFAE), Probiotics (Strains, Spore-Formers, Synbiotic Components) (AFAJAKAE)

Keywords

• Prebiotic fiber ingredients
• Functional food ingredients
• Dietary fiber science
• Food biotechnology
• Gut health ingredients

Headquarters

HQ city

Sacramento

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain

Revenue model

1. B2B Ingredient Sales: one.bio sells its proprietary prebiotic oat fiber ingredient (one.bio 01) to food and beverage manufacturers who want to add functional fiber benefits to their products. The ingredient is designed to be invisible in final products, allowing brands to enhance nutritional profiles without affecting consumer experience.
2. Direct-to-Consumer Consumer Products: One.bio parent One Unlimited sells finished consumer products (GoodVice protein shakes) directly to consumers through DrinkGoodVice.com, positioning products as proof-of-concept for the fiber science platform.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels4 records

Core offering

one.bio develops and sells proprietary prebiotic oat fiber ingredients (one.bio 01, OneBio Invisible Oat Fiber) to food and beverage manufacturers, with the capability to deliver clinically validated fiber signals (gut, metabolic, immune health) at high doses without affecting taste, texture, or color of finished products. The company also sells GoodVice branded protein shakes directly to consumers as a proof-of-concept showcase for the underlying fiber science platform.

Product overview

one.bio is a fiber science platform consisting of a core ingredient technology (one.bio 01 prebiotic oat fiber) and a proprietary Glycopedia database that maps fiber molecular structures to gut microbiome behavior. The company also operates GoodVice, a consumer brand that serves as proof-of-concept for the technology through nutritional shakes. The platform enables the formulation of fiber ingredients that are imperceptible in foods and beverages while delivering targeted biological signals for gut, metabolic, and immune health.

Differentiator

Problem solved

Functional benefit

Brands

• GoodVice: Functional dairy beverage line featuring one.bio 01 prebiotic oat fiber, launched as proof-of-concept for one.bio's fiber science platform.

Products and services

• one.bio 01 Clinically validated prebiotic oat fiber ingredient designed to deliver gut, metabolic, and immune health benefits while remaining imperceptible in taste and texture. Demonstrated digestive comfort, stabilized blood sugar, and improved mood in a 14-day clinical study with 63 adults. Sold to food and beverage manufacturers as a B2B ingredient.
• OneBio Invisible Oat Fiber Clean, versatile prebiotic oat fiber ingredient launched to deliver gut health, metabolic wellness, and nutritional benefits to food and beverage products without affecting taste, texture, or color. Positioned for the 'fibermaxxing' consumer trend and supports high-dose fiber inclusion in finished formulations.
• GoodVice Consumer nutritional shake brand featuring one.bio 01 prebiotic oat fiber, offering 10g prebiotic fiber and 15g grass-fed milk protein per serving, plus creatine and magnesium. Serves as proof-of-concept for one.bio's fiber science platform, demonstrating 'Effortless Indulgence' without trade-offs between taste and health. Sold direct-to-consumer through DrinkGoodVice.com.
• one.bio Fiber Formulations Collection of proprietary fiber formulations (FIBER 01, 03, 05, 06, 08, 12, 23, 24) with specific molecular structures designed to produce targeted biological signals including reduced inflammation, beneficial bacteria feeding, gut barrier strengthening, and immune system communication via short-chain fatty acid production (butyrate, propionate, acetate).

Quantifiable outcome

• Significant improvements in mood, focus, and mental clarity in two weeks
• +3 more outcomes

Named customers1 record

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Tate & Lyle: Global ingredient supplier with a major specialty food ingredients portfolio including fibers and prebiotics. Directly comparable as a B2B supplier of functional fiber ingredients to CPG manufacturers, but operates across a much broader ingredient portfolio rather than specializing in prebiotic fibers.
• Ingredion: Major ingredient supplier offering corn, tapioca, and oat-based fibers for food and beverage formulation. Comparable B2B motion and customer base; serves the same CPG manufacturers with functional fiber ingredients but across a much wider ingredient catalog.
• Cargill: Global agribusiness with significant food ingredients operations including prebiotic and soluble fibers for CPG applications. Competes directly in the B2B functional fiber space but as one ingredient category within a vast portfolio spanning oils, proteins, and sweeteners.
• Roquette: Global starch and ingredient company with a substantial portfolio of plant-based functional ingredients including prebiotic and soluble fibers. Comparable B2B supplier of functional fibers for food and beverage formulation across global CPG customers.
• ADM: Major global ingredient supplier with a wide portfolio spanning flavors, fibers, and prebiotics for CPG applications. Comparable in customer base and B2B ingredient motion, though one.bio is significantly more specialized in prebiotic oat fiber.

Direct peers

• BENEO: Specializes in functional ingredients including prebiotic chicory root fibers (inulin, oligofructose) and oat beta-glucan for gut health and metabolic wellness applications. One of the closest comparables to one.bio 01 in target customer, mechanism, and health positioning.
• Clasado Biosciences: Specialist prebiotic ingredient company centered on galactooligosaccharide (GOS) prebiotics for gut health. Directly comparable as a science-led, niche-focused prebiotic B2B ingredient supplier targeting the same health-claim-driven CPG customers.
• Prenexus Health: Developer of prebiotic ingredients (e.g., Prebiotic Fibersol) for food, beverage, and supplement applications. Closely comparable as a science-backed specialty prebiotic ingredient supplier selling into the same gut-health-focused B2B market.

Emerging players

• Olipop: Functional beverage brand built around prebiotic fiber positioning for gut health. Comparable to GoodVice as a consumer-facing brand demonstrating proof-of-concept for prebiotic fiber science, although Olipop is in carbonated sodas rather than protein shakes.
• Poppi: Prebiotic soda brand positioning itself around apple cider vinegar and prebiotic fiber for gut health. Comparable to GoodVice as a category-defining consumer brand proving out the prebiotic/fiber wellness trend, though in carbonated beverages rather than shakes.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks7 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/onebioinc

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries1 record

Funding overview

Funding rounds4 records

Investors16 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about one.bio